LOCUS       NM_028982               4225 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus family with sequence similarity 234, member B
            (Fam234b), transcript variant 2, mRNA.
ACCESSION   NM_028982
VERSION     NM_028982.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4225)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4225)
  AUTHORS   Yu,X., Bauer,K., Koczan,D., Thiesen,H.J. and Ibrahim,S.M.
  TITLE     Combining global genome and transcriptome approaches to identify
            the candidate genes of small-effect quantitative trait loci in
            collagen-induced arthritis
  JOURNAL   Arthritis Res Ther 9 (1), R3 (2007)
   PUBMED   17244351
REFERENCE   3  (bases 1 to 4225)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC131718.5, AK039401.1 and BC079676.1.
            
            On Oct 22, 2009 this sequence version replaced NM_028982.3.
            
            Transcript Variant: This variant (2) uses an alternate splice
            junction in the 3' end compared to variant 1, that causes a
            frameshift. The resulting isoform (2) has a shorter and distinct
            C-terminus compared to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079676.1, AK039401.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-65                AC131718.5         13505-13569         c
            66-2218             AK039401.1         2-2154
            2219-4225           BC079676.1         2146-4152
FEATURES             Location/Qualifiers
     source          1..4225
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 66.02 cM"
     gene            1..4225
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /note="family with sequence similarity 234, member B"
                     /db_xref="GeneID:74525"
                     /db_xref="MGI:MGI:1921775"
     exon            1..115
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..1953
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /note="isoform 2 is encoded by transcript variant 2;
                     protein FAM234B"
                     /codon_start=1
                     /product="protein FAM234B isoform 2"
                     /protein_id="NP_083258.2"
                     /db_xref="CCDS:CCDS39681.1"
                     /db_xref="GeneID:74525"
                     /db_xref="MGI:MGI:1921775"
                     /translation="MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQQK
                     NGGVKNGKSALGDLPEPDSDADVAGAAKPHLSEVTPEGFPSEPLGGLEQKATSPLVSY
                     VRTSVFLLTLVISMVLVLLCAFLIPCPPRDLHSAWSRRLGSQGGGDLSPLELADVNRD
                     GLRDVLLTFVTTRNGTEGGVGSQPTADLVCLSGMNGSTLWSSPLPEEAQDVTCLDLIP
                     GSVAKTICLVTGTRKMLSAFNATSGKVLWTLNPNHLSNGTLAAPVVVLPDLDEDGVRD
                     LVVLAIGELQPDLCFLLVSGRTGSPVGRPVKYNIVGVGNLIGPQVYITASGAVYILFG
                     FGNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKHRSVNLSELIDVYSDGVELLQLV
                     KAPDSNSSSLLITTRQGLVLLRGQDLTPHWKLNLQGLRSQPTPGYFTDDQTLDFLLQT
                     QDGDGMKKMTVVDGGSGSIVWSYSIPCHMKETPTTSAITSDQKSVFLFWAEALTAASL
                     SSDDSSGAEPPGLYHLYLLHPAFPSILLDLSNTTGIVTASEVGINDIWKDAFYVTRTT
                     GMSPEGHPTSLVVSKLSLRWALMEGQMVQLKETTPKIGRGELRRFLSRIKFVDSPYQI
                     "
     exon            116..514
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            515..613
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            614..805
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            806..936
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            937..1084
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1226
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1370
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            1371..1452
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            1453..1608
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            1609..1726
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            1727..1947
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            1948..4209
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4187..4192
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /note="hexamer: AATAAA"
     polyA_site      4207
                     /gene="Fam234b"
                     /gene_synonym="8430419L09Rik; mKIAA1467"
                     /note="major polyA site"
ORIGIN      
        1 gcagccccac gcgcggttcg cagcgaacta cacttcccgg caggacgcgg cgcgcgcacg
       61 cgcacggggg cctccgccat ggcgacagtg ctgtccaggg ctctcaagct cccggggaag
      121 aagagcccag acctcggtga gtacgacccc ctcacgcagg ccgacagtga tgagagcgaa
      181 gatgatctcg tgcttaactt gcagcagaag aatggagggg tcaaaaacgg gaagagtgcc
      241 ctgggagacc tgccagagcc cgactcagat gccgatgtgg ctggggcggc aaagccacat
      301 ctttcagaag tcaccccaga gggtttcccc tcggaacccc ttgggggcct ggagcagaag
      361 gccacctctc ccctggtgtc ctatgtgcgc acgtctgtct tcctgctgac actggtgatc
      421 tccatggttc tggtattgct ctgcgccttc ctcatcccct gccctcccag agacctgcat
      481 agcgcttgga gccggcgcct gggctcccaa ggaggcgggg acctgtctcc cctggagttg
      541 gctgacgtga atagagatgg tctgcgggac gtgctgctca cctttgtgac aaccaggaat
      601 gggactgaag gaggtgttgg ctcacaacca actgcagatc tggtgtgcct ttcggggatg
      661 aacggcagca cactgtggtc cagtcccctc ccagaggagg ctcaagatgt cacatgctta
      721 gatctgatac caggaagtgt ggccaaaacc atctgccttg tgacggggac tcgcaagatg
      781 ctcagcgcat tcaatgcgac gtcagggaaa gtcctctgga ctctgaaccc aaaccatctg
      841 tccaacggta ccttggcagc cccggttgtg gtgctgccag accttgatga agatggtgtc
      901 agagatctgg tggtgctggc cattggagaa ctgcagccag atctgtgttt tctgctggta
      961 tctggccgga cagggagtcc tgtgggccga cctgtgaagt ataacatcgt gggagtaggg
     1021 aatctgattg gtccccaggt ttacatcacc gccagtggag ctgtctacat cctgtttggc
     1081 tttggaaaca tacaagctgt cgccctgcgg gacatttttg ttcaggccca aaatcgggac
     1141 agctcgccac cctctctgca gatagaggag ccggagtggg agaagcacag atctgtcaac
     1201 ctttcagagc tcatcgatgt ttacagtgat ggagttgagc ttctccagtt ggtgaaggcg
     1261 ccagattcca acagcagcag cctcctgatt acaacccgac aaggcctggt cctgcttaga
     1321 ggacaagatc ttacgcctca ttggaaactg aaccttcagg gcctgcgcag ccagcccact
     1381 cctgggtatt tcactgatga ccagacattg gacttccttc tgcagacaca agatggagat
     1441 gggatgaaaa agatgacagt ggtagatgga ggttctggct ccatcgtctg gagttacagt
     1501 attccatgtc acatgaagga aacgccaacc acttctgcaa ttacttcaga ccagaagtct
     1561 gtcttcctct tctgggcaga ggcactgact gctgcatctc tcagttctga cgacagctca
     1621 ggagcggagc ctcctggcct ttaccacctt tacctcctgc acccagcctt cccctccatc
     1681 ctcctggacc tgagcaacac cactggcata gtgacagctt cggaggttgg aatcaacgac
     1741 atctggaaag atgcctttta tgtcaccagg acaacaggga tgagccctga aggacaccct
     1801 acctctctgg tggtcagcaa gcttagcctg cgctgggcac tcatggaagg ccagatggtc
     1861 cagctgaagg agaccacccc taaaattggc cgtggggaac tgcgaagatt cctgtctagg
     1921 ataaagtttg ttgattctcc ctaccagatc tagtgcaacg gaattctccg gattcagaac
     1981 aacttgacgg actggctcct gtctctcctg catcagttct cttgagagag gatgacttca
     2041 gggttgtgca gcacttggga tcactgtcct gcggcagcgt gttgaagctg agatgtagca
     2101 tggtccgctt agctggggaa cctcacgacc tttccgtccc cacgctaacc ccttctcccg
     2161 agaactctgt gtggatactt tggaaatgtg aatcttatag ctgttttaat ttttttttgt
     2221 acctttaatt tataaaccct tgtggggaaa gccagtgacc tacaagcagg atatatgttg
     2281 ttttgcctta ggccctgtgt gtctctctgt gtatgtgtgt gtgtctctgt atgtgtgtgt
     2341 gtgcccagtg ttgtaacaat tattcttgag atatgcccca agcttcaggg attccgtttc
     2401 ctgtcctggt gaagttcatc tggcttggcc atcttgatgc ggctggatgg cctatctctg
     2461 gtcctgaggg tcgcgcacca ctgttttccc tctgcccgcc tatactgtgg ttcctttcca
     2521 cagcagtgag gaacactgga ggttgtgctg ggggctcgtt atcctgtgtg ctcatctgtc
     2581 tgtctcctag actctccacc cgcagagtgc agacacgctt ctatcacaga gagagcaagg
     2641 gtgcctcgga ccagggcctt gtgccaagcc cttagagctt tgatggctct gcagctgtga
     2701 tctttgattc tgcagcaatg gcagagggtt tgcatgcgca ctgtcctcag tcccatggcc
     2761 ttgtcctgcc gtagctctgc cctctcgccc tgagtctttc ttctctgggg catctccatc
     2821 tcttcccgct tcctctctta ttcagggatc tgtttctgga cttctgcttc ttgggtccgg
     2881 tatgcaacca ctctggcccc gtgtccttcc ctccttgtag agctttgaaa gcatattctg
     2941 agaaagttct cttgtaaata ctgtaacttt tttataatga ccaagttctt tagaattatt
     3001 gccatccttt tctgccccct tctaggtaag tgtgtgacct cttttaactc tttcaaatgt
     3061 ctatgtcatt atctgtcatg ctgtctgttc tcatggtggc caatgaaaac acacttctct
     3121 tgagggaaag ccagattctc atctcacttg ggcatgtatg tctttttagc ttctgttaat
     3181 aaatttcagg aaacgtagat tctaggttta aggggctaac tatgagttgc ccacaagagg
     3241 tgttatgggt agcagaggtt ggtccttgga ccacccagca gattggcctc accagacttg
     3301 ttggtacgtc tgccagaaag agcagaaaag catatttgga agtcatatgg gaccaggttg
     3361 accttgggga gggggaaaca atgaatagga tcctttagag tctggagatg attctaggtt
     3421 atttctagta agttgaattt ctgccagtga aagggtttag aatatagttt ggagtgtgga
     3481 ctagttttca gtggaccaac acgggagatg ggtgggggtc ctctggcctg cttgagccct
     3541 tgtaggccca gtgttctctg cagtgttgtt ctcagagaag ccagcctgtg caggaagggg
     3601 gaagatacaa ggctgctcaa tggagtgctt gggttgttgc tcggcctgga ggctgtttat
     3661 gctggttgag tcttagctga gaggaagctc cacagacaat atccctgaat taacatccta
     3721 acttcttcct agaagtgtga atcgcttccc tgctgaatgc aatgcaaact ctaggcttac
     3781 ttcctgttgc agctggttat agaaaggtag ctgagggttg agatggcttc atctggcctc
     3841 ctgtcaaagg cctcctctaa accctcctcc ttgtaggcaa caacttcccc agatattcaa
     3901 gataggaagt gttcaatgag ggcagcccac agaatcagcc tgagcacacc tcagtagtgc
     3961 tgtctgcatg gcaagggtct cccctcctct cagcctctcc cttccttcct ttgtaagccc
     4021 tcctgcctct gccctgcaca gcacccccac aggcccccaa acatgtggtg cggtgatacc
     4081 gactaacccc aggaatgtga attgctgtcc acgttacctg cattgaggag cagcccgggg
     4141 tttgttgcca ggaagtaagg tttaaaatgt gaactgctac agaacaaata aatgctgtgt
     4201 acaggaataa aaaaaaaaaa aaaaa
//
