LOCUS       NM_207217               2662 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus family with sequence similarity 234, member A
            (Fam234a), transcript variant 2, mRNA.
ACCESSION   NM_207217 XM_128606
VERSION     NM_207217.5
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2662)
  AUTHORS   Gineste,C., De Winter,J.M., Kohl,C., Witt,C.C., Giannesini,B.,
            Brohm,K., Le Fur,Y., Gretz,N., Vilmen,C., Pecchi,E., Jubeau,M.,
            Cozzone,P.J., Stienen,G.J., Granzier,H., Labeit,S.,
            Ottenheijm,C.A., Bendahan,D. and Gondin,J.
  TITLE     In vivo and in vitro investigations of heterozygous nebulin
            knock-out mice disclose a mild skeletal muscle phenotype
  JOURNAL   Neuromuscul Disord 23 (4), 357-369 (2013)
   PUBMED   23375831
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC126438.3.
            
            On Jan 20, 2022 this sequence version replaced NM_207217.4.
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Variants 1-3 and 5-7 all encode the same
            isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK029427.1, SRR7974084.6257.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-155               AC126438.3         61092-61246
            156-455             AC126438.3         84672-84971
            456-572             AC126438.3         86501-86617
            573-767             AC126438.3         86934-87128
            768-904             AC126438.3         87822-87958
            905-1037            AC126438.3         88561-88693
            1038-1167           AC126438.3         88934-89063
            1168-1308           AC126438.3         89927-90067
            1309-1384           AC126438.3         90525-90600
            1385-1540           AC126438.3         90769-90924
            1541-1643           AC126438.3         91346-91448
            1644-2662           AC126438.3         91535-92553
FEATURES             Location/Qualifiers
     source          1..2662
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 13.07 cM"
     gene            1..2662
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /note="family with sequence similarity 234, member A"
                     /db_xref="GeneID:106581"
                     /db_xref="MGI:MGI:2146854"
     exon            1..155
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            156..455
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     CDS             188..1855
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /note="isoform 1 is encoded by transcript variant 2;
                     protein ITFG3; protein FAM234A"
                     /codon_start=1
                     /product="protein FAM234A isoform 1"
                     /protein_id="NP_997100.1"
                     /db_xref="CCDS:CCDS37512.1"
                     /db_xref="GeneID:106581"
                     /db_xref="MGI:MGI:2146854"
                     /translation="MMDNKDLEAEIHPLKNEDKKSQENPGNLPRNEDNLKSKPVPSRL
                     SRCRTVAFFLSLFTCLFVVFVLSFIIPCPDRPSSQGTWKLDYNNAVMYDFLALGDINK
                     DKVQDVLFLYKNTNSSNNLTRSCADEGFSTPCAFVVAVSGANGSVLWERPVAQDVALV
                     KCAMPQTLDSDEVSSACIVVGRAGSFVAVSFFTGETLWSHPSSFSGNVSILSPLLQVP
                     DIDGDGDGTPDLLILAQEGQEVSGALYSGSTGYQIGHRGSLGVDGDGVALLHVTRTGA
                     QYILLPCASALCGFSVKSLYERITGRDGHFKEDPYWENMLNHSVHRRLLHRLGAVRYL
                     MNIPGKAGQDLLLVTSEACVLLDGQDLEPRWTLGEVQVLRKPILGHYKPDTLAVVIEN
                     GTSIDRQILLLDLSTGSILWSQPLPSLPGGPPSTSLMTADHRSAFFFWGLHDLVSTNE
                     MDPPDVQHSLYMFHPTLPGILLELANVSANIVAFDAVLLEPSRHAAYVLLTGPASSDV
                     PGLVSVTKHKVQDLVPGSRVIHLGEGSSDSDQAIRDRFSRLRYRSEM"
     exon            456..572
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            573..767
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            768..904
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            905..1037
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1038..1167
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1168..1308
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1309..1384
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1385..1540
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1541..1643
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1644..2662
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2616..2621
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /note="hexamer: AATAAA"
     polyA_site      2662
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /note="major polyA site"
ORIGIN      
        1 gctgtccggc gtagtctgta ctcctgttca gccgctgtcc tcccgggaac cttggggatg
       61 tggatcccgg attccaggga ccgcagttga gccagcctcg ccagtcctgt accacttgct
      121 gaggagcagg atctcgcgga caggtccgag agcagtggcc acagttaagc tctggaatgt
      181 gctcaggatg atggacaaca aggacttaga agctgaaata caccccttga agaatgagga
      241 caagaaatca caggaaaacc caggaaacct accaagaaac gaagataact tgaagagcaa
      301 gcctgtgcct tcccgcttgt cccggtgccg cacagtggca tttttccttt ccctgttcac
      361 ctgcctcttc gtggtgtttg tcctgtcttt catcatccca tgtccagacc gtccctcctc
      421 acagggcacg tggaagcttg actacaacaa tgcagtcatg tacgacttcc tggctctggg
      481 agacataaac aaggacaagg ttcaggacgt tctttttctt tacaaaaata ccaacagcag
      541 taacaatctc accagatcct gtgctgatga aggcttttcc actccttgtg cctttgtggt
      601 tgcggtgtca ggagccaatg gcagcgtgct ctgggagaga cccgtggccc aagatgtcgc
      661 ccttgtaaag tgtgccatgc cacagacact ggacagtgac gaggtgtctt ctgcctgtat
      721 cgttgtggga agagctggtt ctttcgttgc ggtcagcttt tttacaggag aaaccctgtg
      781 gagccatccc agcagcttta gtgggaacgt ttccatcctg agccctctgc tccaggtgcc
      841 tgacattgat ggtgatggtg acggtactcc agacctcctg atcctcgccc aggagggaca
      901 ggaggtcagt ggagctctct attcaggtag cactgggtac cagattggcc acagaggcag
      961 ccttggtgtg gatggagatg gtgtcgccct ccttcatgtg accagaactg gtgctcagta
     1021 tattctcctg ccctgtgcaa gtgccctctg tggcttctct gtgaagagtc tctatgagag
     1081 aattactggg cgagatggcc attttaagga agacccctac tgggagaaca tgctcaatca
     1141 ctctgtccac aggaggcttc tgcacagact tggagcagtt cgctacctga tgaatatccc
     1201 agggaaagct ggccaggact tgctccttgt gacctctgag gcctgcgtgt tgctggatgg
     1261 acaggatctg gagcccaggt ggacccttgg tgaagttcag gttctgagaa aacctatcct
     1321 tggccactac aaacctgaca ccttggctgt ggtcattgag aatggaacca gcattgatag
     1381 acagatccta cttctggacc tcagtactgg gtctatcctg tggagccagc ccctcccaag
     1441 cctgcctggg ggcccaccat ccacaagcct gatgactgca gaccaccgct cagccttctt
     1501 cttctggggc ctccatgatc ttgtgagcac taatgagatg gatcccccgg atgtgcagca
     1561 cagtctgtat atgttccacc cgaccctgcc tggcatcctg ctggagctag ccaacgtgtc
     1621 tgccaacatc gtggcctttg atgccgtcct gcttgagcca agccgccatg ctgcctatgt
     1681 gctcctgacg ggcccagcaa gctcagatgt gcctggcctg gtctctgtca ccaaacacaa
     1741 agtgcaagac cttgtcccag gcagtagagt gatccacttg ggtgaaggca gctcagacag
     1801 cgaccaggct atccgggacc ggttctcccg actacggtac cggagtgaga tgtaggtgtt
     1861 gtcggctgga gcacacggag agattccaac tgtgaaaagg aagcctcttg gaaagctggc
     1921 ctgctctcgg ccttcatgct gacctcactg ctcgccctga tgattcgggc cctctggagc
     1981 tatggcctta ccagttctac ccaggatgtt gagagtgggg ggcaccttcc agcctcctgc
     2041 ccataccatg tcctccctca aaggtctcac tgcgtggccc actgatctgg tcaagtaagg
     2101 ctccctgggc tggcttgggc aaggcagccc acaggaggct catttatcac ttcctgcctc
     2161 cttaccctct cccaggaaag ccaccactgt gtgctgtgct gctccctagt ccctctcagg
     2221 ccagcctggc tttccccatt tcggcactgt ccctcagggg tcacgaaact cagggctgta
     2281 gctggaacct gaggcttgga agctgcttcc ccacagcaga agggagcatg tctcctggaa
     2341 agcgagcaac cctgagtctg accagagcct ccgggtgcga gggatttcca gactgtacgc
     2401 tgagtcagtc cttcgcctca gtacactgtc cctgcaccct ggcacagcgg gcacgtctct
     2461 ttccctactc tggtgcttat ctgatggcgg tctcaccttg tgccttgttt gttgttcctg
     2521 aagcccaagg gcaacagagc agctttgccc agatcacatc catagctctg tagccaaagc
     2581 agtcccatga ccccagccac catggaaacc aacacaataa acgatttgca ctgatgggga
     2641 aagcccccgt agtccagcgt ga
//
