LOCUS       NM_001374603            2660 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus family with sequence similarity 234, member A
            (Fam234a), transcript variant 4, mRNA.
ACCESSION   NM_001374603
VERSION     NM_001374603.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2660)
  AUTHORS   Gineste,C., De Winter,J.M., Kohl,C., Witt,C.C., Giannesini,B.,
            Brohm,K., Le Fur,Y., Gretz,N., Vilmen,C., Pecchi,E., Jubeau,M.,
            Cozzone,P.J., Stienen,G.J., Granzier,H., Labeit,S.,
            Ottenheijm,C.A., Bendahan,D. and Gondin,J.
  TITLE     In vivo and in vitro investigations of heterozygous nebulin
            knock-out mice disclose a mild skeletal muscle phenotype
  JOURNAL   Neuromuscul Disord 23 (4), 357-369 (2013)
   PUBMED   23375831
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC126438.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.597064.1,
                                           SRR7345562.3763092.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-171               AC126438.3         61092-61262
            172-471             AC126438.3         84672-84971
            472-588             AC126438.3         86501-86617
            589-783             AC126438.3         86934-87128
            784-920             AC126438.3         87822-87958
            921-1053            AC126438.3         88561-88693
            1054-1183           AC126438.3         88934-89063
            1184-1324           AC126438.3         89927-90067
            1325-1400           AC126438.3         90525-90600
            1401-1538           AC126438.3         90769-90906
            1539-1641           AC126438.3         91346-91448
            1642-2660           AC126438.3         91535-92553
FEATURES             Location/Qualifiers
     source          1..2660
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 13.07 cM"
     gene            1..2660
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /note="family with sequence similarity 234, member A"
                     /db_xref="GeneID:106581"
                     /db_xref="MGI:MGI:2146854"
     exon            1..171
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            172..471
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     CDS             204..1853
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /note="isoform 2 is encoded by transcript variant 4;
                     protein ITFG3; protein FAM234A"
                     /codon_start=1
                     /product="protein FAM234A isoform 2"
                     /protein_id="NP_001361532.1"
                     /db_xref="GeneID:106581"
                     /db_xref="MGI:MGI:2146854"
                     /translation="MMDNKDLEAEIHPLKNEDKKSQENPGNLPRNEDNLKSKPVPSRL
                     SRCRTVAFFLSLFTCLFVVFVLSFIIPCPDRPSSQGTWKLDYNNAVMYDFLALGDINK
                     DKVQDVLFLYKNTNSSNNLTRSCADEGFSTPCAFVVAVSGANGSVLWERPVAQDVALV
                     KCAMPQTLDSDEVSSACIVVGRAGSFVAVSFFTGETLWSHPSSFSGNVSILSPLLQVP
                     DIDGDGDGTPDLLILAQEGQEVSGALYSGSTGYQIGHRGSLGVDGDGVALLHVTRTGA
                     QYILLPCASALCGFSVKSLYERITGRDGHFKEDPYWENMLNHSVHRRLLHRLGAVRYL
                     MNIPGKAGQDLLLVTSEACVLLDGQDLEPRWTLGEVQVLRKPILGHYKPDTLAVVIEN
                     GTSIDRQILLLDLSTGSILWSQPLPSLPGGPPSTSLMTADHRSAFFFWGLHDLDPPDV
                     QHSLYMFHPTLPGILLELANVSANIVAFDAVLLEPSRHAAYVLLTGPASSDVPGLVSV
                     TKHKVQDLVPGSRVIHLGEGSSDSDQAIRDRFSRLRYRSEM"
     exon            472..588
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            589..783
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            784..920
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            921..1053
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1183
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1184..1324
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1325..1400
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1401..1538
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1641
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1642..2660
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2614..2619
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /note="hexamer: AATAAA"
     polyA_site      2660
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /note="major polyA site"
ORIGIN      
        1 gctgtccggc gtagtctgta ctcctgttca gccgctgtcc tcccgggaac cttggggatg
       61 tggatcccgg attccaggga ccgcagttga gccagcctcg ccagtcctgt accacttgct
      121 gaggagcagg atctcgcgga caggtccgag agcaggtcag gatcggacta gtggccacag
      181 ttaagctctg gaatgtgctc aggatgatgg acaacaagga cttagaagct gaaatacacc
      241 ccttgaagaa tgaggacaag aaatcacagg aaaacccagg aaacctacca agaaacgaag
      301 ataacttgaa gagcaagcct gtgccttccc gcttgtcccg gtgccgcaca gtggcatttt
      361 tcctttccct gttcacctgc ctcttcgtgg tgtttgtcct gtctttcatc atcccatgtc
      421 cagaccgtcc ctcctcacag ggcacgtgga agcttgacta caacaatgca gtcatgtacg
      481 acttcctggc tctgggagac ataaacaagg acaaggttca ggacgttctt tttctttaca
      541 aaaataccaa cagcagtaac aatctcacca gatcctgtgc tgatgaaggc ttttccactc
      601 cttgtgcctt tgtggttgcg gtgtcaggag ccaatggcag cgtgctctgg gagagacccg
      661 tggcccaaga tgtcgccctt gtaaagtgtg ccatgccaca gacactggac agtgacgagg
      721 tgtcttctgc ctgtatcgtt gtgggaagag ctggttcttt cgttgcggtc agctttttta
      781 caggagaaac cctgtggagc catcccagca gctttagtgg gaacgtttcc atcctgagcc
      841 ctctgctcca ggtgcctgac attgatggtg atggtgacgg tactccagac ctcctgatcc
      901 tcgcccagga gggacaggag gtcagtggag ctctctattc aggtagcact gggtaccaga
      961 ttggccacag aggcagcctt ggtgtggatg gagatggtgt cgccctcctt catgtgacca
     1021 gaactggtgc tcagtatatt ctcctgccct gtgcaagtgc cctctgtggc ttctctgtga
     1081 agagtctcta tgagagaatt actgggcgag atggccattt taaggaagac ccctactggg
     1141 agaacatgct caatcactct gtccacagga ggcttctgca cagacttgga gcagttcgct
     1201 acctgatgaa tatcccaggg aaagctggcc aggacttgct ccttgtgacc tctgaggcct
     1261 gcgtgttgct ggatggacag gatctggagc ccaggtggac ccttggtgaa gttcaggttc
     1321 tgagaaaacc tatccttggc cactacaaac ctgacacctt ggctgtggtc attgagaatg
     1381 gaaccagcat tgatagacag atcctacttc tggacctcag tactgggtct atcctgtgga
     1441 gccagcccct cccaagcctg cctgggggcc caccatccac aagcctgatg actgcagacc
     1501 accgctcagc cttcttcttc tggggcctcc atgatcttga tcccccggat gtgcagcaca
     1561 gtctgtatat gttccacccg accctgcctg gcatcctgct ggagctagcc aacgtgtctg
     1621 ccaacatcgt ggcctttgat gccgtcctgc ttgagccaag ccgccatgct gcctatgtgc
     1681 tcctgacggg cccagcaagc tcagatgtgc ctggcctggt ctctgtcacc aaacacaaag
     1741 tgcaagacct tgtcccaggc agtagagtga tccacttggg tgaaggcagc tcagacagcg
     1801 accaggctat ccgggaccgg ttctcccgac tacggtaccg gagtgagatg taggtgttgt
     1861 cggctggagc acacggagag attccaactg tgaaaaggaa gcctcttgga aagctggcct
     1921 gctctcggcc ttcatgctga cctcactgct cgccctgatg attcgggccc tctggagcta
     1981 tggccttacc agttctaccc aggatgttga gagtgggggg caccttccag cctcctgccc
     2041 ataccatgtc ctccctcaaa ggtctcactg cgtggcccac tgatctggtc aagtaaggct
     2101 ccctgggctg gcttgggcaa ggcagcccac aggaggctca tttatcactt cctgcctcct
     2161 taccctctcc caggaaagcc accactgtgt gctgtgctgc tccctagtcc ctctcaggcc
     2221 agcctggctt tccccatttc ggcactgtcc ctcaggggtc acgaaactca gggctgtagc
     2281 tggaacctga ggcttggaag ctgcttcccc acagcagaag ggagcatgtc tcctggaaag
     2341 cgagcaaccc tgagtctgac cagagcctcc gggtgcgagg gatttccaga ctgtacgctg
     2401 agtcagtcct tcgcctcagt acactgtccc tgcaccctgg cacagcgggc acgtctcttt
     2461 ccctactctg gtgcttatct gatggcggtc tcaccttgtg ccttgtttgt tgttcctgaa
     2521 gcccaagggc aacagagcag ctttgcccag atcacatcca tagctctgta gccaaagcag
     2581 tcccatgacc ccagccacca tggaaaccaa cacaataaac gatttgcact gatggggaaa
     2641 gcccccgtag tccagcgtga
//
