LOCUS       NM_001357894            2790 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus family with sequence similarity 234, member A
            (Fam234a), transcript variant 3, mRNA.
ACCESSION   NM_001357894 XM_011246236
VERSION     NM_001357894.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2790)
  AUTHORS   Gineste,C., De Winter,J.M., Kohl,C., Witt,C.C., Giannesini,B.,
            Brohm,K., Le Fur,Y., Gretz,N., Vilmen,C., Pecchi,E., Jubeau,M.,
            Cozzone,P.J., Stienen,G.J., Granzier,H., Labeit,S.,
            Ottenheijm,C.A., Bendahan,D. and Gondin,J.
  TITLE     In vivo and in vitro investigations of heterozygous nebulin
            knock-out mice disclose a mild skeletal muscle phenotype
  JOURNAL   Neuromuscul Disord 23 (4), 357-369 (2013)
   PUBMED   23375831
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC126438.3.
            
            On Jan 20, 2022 this sequence version replaced NM_001357894.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.2053057.1,
                                           SRR1660815.272331.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-171               AC126438.3         61092-61262
            172-283             AC126438.3         79229-79340
            284-583             AC126438.3         84672-84971
            584-700             AC126438.3         86501-86617
            701-895             AC126438.3         86934-87128
            896-1032            AC126438.3         87822-87958
            1033-1165           AC126438.3         88561-88693
            1166-1295           AC126438.3         88934-89063
            1296-1436           AC126438.3         89927-90067
            1437-1512           AC126438.3         90525-90600
            1513-1668           AC126438.3         90769-90924
            1669-1771           AC126438.3         91346-91448
            1772-2790           AC126438.3         91535-92553
FEATURES             Location/Qualifiers
     source          1..2790
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 13.07 cM"
     gene            1..2790
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /note="family with sequence similarity 234, member A"
                     /db_xref="GeneID:106581"
                     /db_xref="MGI:MGI:2146854"
     exon            1..171
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            172..283
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            284..583
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     CDS             316..1983
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /note="isoform 1 is encoded by transcript variant 3;
                     protein ITFG3; protein FAM234A"
                     /codon_start=1
                     /product="protein FAM234A isoform 1"
                     /protein_id="NP_001344823.1"
                     /db_xref="CCDS:CCDS37512.1"
                     /db_xref="GeneID:106581"
                     /db_xref="MGI:MGI:2146854"
                     /translation="MMDNKDLEAEIHPLKNEDKKSQENPGNLPRNEDNLKSKPVPSRL
                     SRCRTVAFFLSLFTCLFVVFVLSFIIPCPDRPSSQGTWKLDYNNAVMYDFLALGDINK
                     DKVQDVLFLYKNTNSSNNLTRSCADEGFSTPCAFVVAVSGANGSVLWERPVAQDVALV
                     KCAMPQTLDSDEVSSACIVVGRAGSFVAVSFFTGETLWSHPSSFSGNVSILSPLLQVP
                     DIDGDGDGTPDLLILAQEGQEVSGALYSGSTGYQIGHRGSLGVDGDGVALLHVTRTGA
                     QYILLPCASALCGFSVKSLYERITGRDGHFKEDPYWENMLNHSVHRRLLHRLGAVRYL
                     MNIPGKAGQDLLLVTSEACVLLDGQDLEPRWTLGEVQVLRKPILGHYKPDTLAVVIEN
                     GTSIDRQILLLDLSTGSILWSQPLPSLPGGPPSTSLMTADHRSAFFFWGLHDLVSTNE
                     MDPPDVQHSLYMFHPTLPGILLELANVSANIVAFDAVLLEPSRHAAYVLLTGPASSDV
                     PGLVSVTKHKVQDLVPGSRVIHLGEGSSDSDQAIRDRFSRLRYRSEM"
     exon            584..700
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            701..895
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            896..1032
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1165
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1295
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1436
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1437..1512
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1513..1668
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1669..1771
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1772..2790
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2744..2749
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /note="hexamer: AATAAA"
     polyA_site      2790
                     /gene="Fam234a"
                     /gene_synonym="Itfg3"
                     /note="major polyA site"
ORIGIN      
        1 gctgtccggc gtagtctgta ctcctgttca gccgctgtcc tcccgggaac cttggggatg
       61 tggatcccgg attccaggga ccgcagttga gccagcctcg ccagtcctgt accacttgct
      121 gaggagcagg atctcgcgga caggtccgag agcaggtcag gatcggacta ggtctgcctg
      181 ggcttatgaa gacaaagccc cccaagacca atgagcagat agatgcccca gcagttggcc
      241 aggatcatct gttgaacacc ccctcaggta ctccaccgac cagtggccac agttaagctc
      301 tggaatgtgc tcaggatgat ggacaacaag gacttagaag ctgaaataca ccccttgaag
      361 aatgaggaca agaaatcaca ggaaaaccca ggaaacctac caagaaacga agataacttg
      421 aagagcaagc ctgtgccttc ccgcttgtcc cggtgccgca cagtggcatt tttcctttcc
      481 ctgttcacct gcctcttcgt ggtgtttgtc ctgtctttca tcatcccatg tccagaccgt
      541 ccctcctcac agggcacgtg gaagcttgac tacaacaatg cagtcatgta cgacttcctg
      601 gctctgggag acataaacaa ggacaaggtt caggacgttc tttttcttta caaaaatacc
      661 aacagcagta acaatctcac cagatcctgt gctgatgaag gcttttccac tccttgtgcc
      721 tttgtggttg cggtgtcagg agccaatggc agcgtgctct gggagagacc cgtggcccaa
      781 gatgtcgccc ttgtaaagtg tgccatgcca cagacactgg acagtgacga ggtgtcttct
      841 gcctgtatcg ttgtgggaag agctggttct ttcgttgcgg tcagcttttt tacaggagaa
      901 accctgtgga gccatcccag cagctttagt gggaacgttt ccatcctgag ccctctgctc
      961 caggtgcctg acattgatgg tgatggtgac ggtactccag acctcctgat cctcgcccag
     1021 gagggacagg aggtcagtgg agctctctat tcaggtagca ctgggtacca gattggccac
     1081 agaggcagcc ttggtgtgga tggagatggt gtcgccctcc ttcatgtgac cagaactggt
     1141 gctcagtata ttctcctgcc ctgtgcaagt gccctctgtg gcttctctgt gaagagtctc
     1201 tatgagagaa ttactgggcg agatggccat tttaaggaag acccctactg ggagaacatg
     1261 ctcaatcact ctgtccacag gaggcttctg cacagacttg gagcagttcg ctacctgatg
     1321 aatatcccag ggaaagctgg ccaggacttg ctccttgtga cctctgaggc ctgcgtgttg
     1381 ctggatggac aggatctgga gcccaggtgg acccttggtg aagttcaggt tctgagaaaa
     1441 cctatccttg gccactacaa acctgacacc ttggctgtgg tcattgagaa tggaaccagc
     1501 attgatagac agatcctact tctggacctc agtactgggt ctatcctgtg gagccagccc
     1561 ctcccaagcc tgcctggggg cccaccatcc acaagcctga tgactgcaga ccaccgctca
     1621 gccttcttct tctggggcct ccatgatctt gtgagcacta atgagatgga tcccccggat
     1681 gtgcagcaca gtctgtatat gttccacccg accctgcctg gcatcctgct ggagctagcc
     1741 aacgtgtctg ccaacatcgt ggcctttgat gccgtcctgc ttgagccaag ccgccatgct
     1801 gcctatgtgc tcctgacggg cccagcaagc tcagatgtgc ctggcctggt ctctgtcacc
     1861 aaacacaaag tgcaagacct tgtcccaggc agtagagtga tccacttggg tgaaggcagc
     1921 tcagacagcg accaggctat ccgggaccgg ttctcccgac tacggtaccg gagtgagatg
     1981 taggtgttgt cggctggagc acacggagag attccaactg tgaaaaggaa gcctcttgga
     2041 aagctggcct gctctcggcc ttcatgctga cctcactgct cgccctgatg attcgggccc
     2101 tctggagcta tggccttacc agttctaccc aggatgttga gagtgggggg caccttccag
     2161 cctcctgccc ataccatgtc ctccctcaaa ggtctcactg cgtggcccac tgatctggtc
     2221 aagtaaggct ccctgggctg gcttgggcaa ggcagcccac aggaggctca tttatcactt
     2281 cctgcctcct taccctctcc caggaaagcc accactgtgt gctgtgctgc tccctagtcc
     2341 ctctcaggcc agcctggctt tccccatttc ggcactgtcc ctcaggggtc acgaaactca
     2401 gggctgtagc tggaacctga ggcttggaag ctgcttcccc acagcagaag ggagcatgtc
     2461 tcctggaaag cgagcaaccc tgagtctgac cagagcctcc gggtgcgagg gatttccaga
     2521 ctgtacgctg agtcagtcct tcgcctcagt acactgtccc tgcaccctgg cacagcgggc
     2581 acgtctcttt ccctactctg gtgcttatct gatggcggtc tcaccttgtg ccttgtttgt
     2641 tgttcctgaa gcccaagggc aacagagcag ctttgcccag atcacatcca tagctctgta
     2701 gccaaagcag tcccatgacc ccagccacca tggaaaccaa cacaataaac gatttgcact
     2761 gatggggaaa gcccccgtag tccagcgtga
//
