LOCUS       NM_145430               3867 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Mus musculus family with sequence similarity 222, member B
            (Fam222b), transcript variant 1, mRNA.
ACCESSION   NM_145430
VERSION     NM_145430.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3867)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK085728.2, AK141119.1, BE332328.1 and AL591070.19.
            
            On Jun 7, 2018 this sequence version replaced NM_145430.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK141119.1, AK085728.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-22                AK085728.2         25-46
            23-3536             AK141119.1         2-3515
            3537-3619           BE332328.1         1-83                c
            3620-3865           AK141119.1         3599-3844
            3866-3867           AL591070.19        192651-192652       c
FEATURES             Location/Qualifiers
     source          1..3867
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 46.74 cM"
     gene            1..3867
                     /gene="Fam222b"
                     /gene_synonym="9630020I17Rik"
                     /note="family with sequence similarity 222, member B"
                     /db_xref="GeneID:216971"
                     /db_xref="MGI:MGI:2384939"
     exon            1..102
                     /gene="Fam222b"
                     /gene_synonym="9630020I17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            103..224
                     /gene="Fam222b"
                     /gene_synonym="9630020I17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             143..1831
                     /gene="Fam222b"
                     /gene_synonym="9630020I17Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C17orf63 homolog; protein FAM222B"
                     /codon_start=1
                     /product="protein FAM222B isoform 1"
                     /protein_id="NP_663405.1"
                     /db_xref="CCDS:CCDS25089.1"
                     /db_xref="GeneID:216971"
                     /db_xref="MGI:MGI:2384939"
                     /translation="MLACLPGPGDLSLQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAE
                     LDAYAKKVANNPLTIKIFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAGLL
                     AIVKVPAKSILKDFDGTRARFLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQH
                     AQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQQMAQTQGLVHPQALTHQG
                     LQHPPNPLLHGGRKMPDSDAPPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFC
                     QTRAGISTTSVCEGQIANPSPISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAAT
                     AALPAAGPVNLPTGISRAPTGYPSDLKPVTWNQHQLAHLQQMCSEAGGTPAPGLTGKH
                     TAGRELAGPGFVGKAAAYPQELCLAQSFHLKPPLEKPTPSPPVNGLPAPLAYPNGHYF
                     QPLWNNILPTPNSDSSGSQDLTMPFHGGQPTGAPLDCGAAPGAHYRAGTGGGPVASQN
                     SLMQTVDYLSGDFQQACFREQSLAMLSKAHRAPGTRAPDPTDSRSLHIQHPGYR"
     exon            225..3867
                     /gene="Fam222b"
                     /gene_synonym="9630020I17Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      3235
                     /gene="Fam222b"
                     /gene_synonym="9630020I17Rik"
                     /note="major polyA site"
     polyA_site      3266
                     /gene="Fam222b"
                     /gene_synonym="9630020I17Rik"
     polyA_site      3288
                     /gene="Fam222b"
                     /gene_synonym="9630020I17Rik"
     regulatory      3853..3858
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam222b"
                     /gene_synonym="9630020I17Rik"
                     /note="hexamer: AGTAAA"
     polyA_site      3867
                     /gene="Fam222b"
                     /gene_synonym="9630020I17Rik"
ORIGIN      
        1 agtccggacg gcggctgtga ttgagaggct ggggcgtgga gcagcagtgg cggcgaccgg
       61 cgacaacgga gcagccatga gggccgggcc cagtcaccga catgtgagcc actgcttcat
      121 gttgtgctga tgctggtctg ccatgctagc ctgtctccca ggaccaggtg acctgtccct
      181 tcagcttctt tctcacacgc agatgaacac tggacttcag aaatgggaca ctacacagaa
      241 aatgagaact gctcactatc ccaccccagc cgaattggac gcgtatgcta agaaggtcgc
      301 aaacaaccca ctgactataa aaatcttccc caacagtgtg aaggttcccc agcggaaaca
      361 cgttcgtcgt actgtgaacg gcctcgacac atcagcccag cgctacagcc cctacccgac
      421 tcaggccgcc accaaggcag gcctgcttgc cattgtcaaa gtgccagcca aaagcatact
      481 caaggacttt gacggcaccc gagctcggtt cctccctgag gccatcatga accccccagt
      541 ggcaccctat gctactgtgg cacccagcac tttagcccac ccacaggccc aggctctggc
      601 ccgccagcag gctctgcagc atgcacagac cctggcccat gcccctcccc agacactgca
      661 acaccctcag ggtataccac caccacaggc actgtctcac cctcagagcc tccagcagcc
      721 tcagggcctg ggccaccctc agcagatggc ccaaacccag ggcttggtcc accctcaggc
      781 cctgactcat cagggtctcc agcacccccc taatcccttg ctgcatggag gccggaagat
      841 gccagactca gatgcacccc cgaatgtgac cgtgtctacc tcaactatcc ccctttcaat
      901 ggcggccacc ctgcaacaca gccagccccc ggacctgagc agcattgtgc accagatcaa
      961 ccagttttgc cagacgaggg caggcatcag cactacctca gtgtgtgagg gccagatcgc
     1021 caaccccagc cctattagtc gcagtctgct catcaatgca agcacccggg tgtcgaccca
     1081 cagcgtcccc acaccaatgc cttcatgtgt ggtcaatccc atggagcaca cccacgcggc
     1141 cacagccgca ctgcctgctg caggtcctgt caacctgccc acaggcatct ctcgagcccc
     1201 cactggctac cctagcgacc tcaagccagt tacctggaac cagcaccagc tggctcacct
     1261 acaacagatg tgcagcgagg ccggtgggac gccagcccct ggcctgacag gcaaacatac
     1321 agcaggacgt gagttggcag ggcctggttt tgtgggcaag gccgctgcct acccacagga
     1381 actctgcctg gcacagtcct tccatctgaa gccacccctg gagaagccga ccccatcccc
     1441 accggtcaac ggcctaccag ccccactggc ctacccgaat ggccactact tccaacccct
     1501 gtggaacaac attctaccaa ctcccaatag cgacagctcg gggtctcaag acctaaccat
     1561 gccattccat ggtgggcagc ccacgggtgc acccctcgac tgtggggcag ctcctggggc
     1621 ccactaccga gcagggactg ggggtggtcc agtggcaagc cagaacagct tgatgcaaac
     1681 ggtggattac ctgagtgggg atttccagca ggcctgcttc cgagaacaga gcctggccat
     1741 gttgagcaaa gcccaccgag ctcctggcac ccgagcccct gatcccacag atagtcgaag
     1801 tcttcatatt cagcacccag ggtatagata gggagccggg acgctctcct caggcaacac
     1861 acattgccct tctaggttta gtcttacttt taagtaactg gatagtttca aagcttccct
     1921 gctccagtgt gatcatcctg agatgtctaa ggaagggaac ttggccgggt cgatttgggg
     1981 gcagaagaag gtcctttatc cttccctcaa gcaactcttg gtttcctgtt agatcctaac
     2041 cctgtcttct cagcagctgt ctgtcaggca gtctccaccc tgaccacttc tgactctcgc
     2101 catcttttgc taaacatcta tttctttggg gactaagtta tgactgaggg gagtggccta
     2161 ggcccttaag gtaggcttct cggtctggga ctaagaaacc agacttccta agtgctctgg
     2221 aagctaattc cgtatgtccc ccaaagatca gcataaaggc actccgccgt ctctcccaag
     2281 ccctcagggc ttggtgctca tttctgttgt tctcaagcca ctgctcttgt ccctgccaaa
     2341 gccttgcgac tcagagaaaa ccattgcatt ggcatcttgg ttcttgactc tcctttgcag
     2401 agaaatgcag tggccatctg gcattcccag gacctcctgt caccgttgcc tctgtccaaa
     2461 ctcagctatt gtcctcaatc ctgcctaccc tccctcctaa gagaaacaaa ccagaaacta
     2521 ccttacttga agaattagtt ctaggtaaag gatgatcaca ctagagtttg gaattaaaaa
     2581 caccaaaaaa gtttgaaaaa aaaaagttta aaaatgcatt tggttctcta cactggctaa
     2641 gaatcactgg tccacactgt aagttctaat gtcgtgtctc tgtatgaatg agtggtttga
     2701 ggagcattgt gtatgagtgc cccacaggta cagtcaccct ctaagttttg cagcccttca
     2761 gtttaatgaa gaacaaaagg aaaaacacaa agccttaagc cccttcaatt cctcctccac
     2821 caaacgtgcg tggttccgac cgctgcagag gggcttacat tgggaatggc ccctcttgcc
     2881 cctcacccat tcaagagcat cttccacctg ttccaggacc aatgtgtctc attcccaagt
     2941 ggcaattagt tgtctagaaa ttcaacactt ctctgtaacg ttagactgtt ttgttgtaaa
     3001 ttcttgcacc tgtcttctgt tgcacagttg ggctttgaaa gtaatagtac taagcccttg
     3061 cctttcctcg ccttggggga atgtgagctg ataactgaag gtctggggtt tattctcact
     3121 gttccttagc cagaaattct gtagtgatct gaagcaatgt gactgaagac cagtttttaa
     3181 attatgtgtt ggcaagttgc cttatattta aaagaaggaa aaaaaaaagg aaaaatgcct
     3241 gcgtgtgtta tgccaaatga tagcaacacg aagtcctaat ttattgtttc cttgctgtct
     3301 gagcactggt atcactgtcc tgtccccgag cccctcagct tctggtgcaa tgcctcctcc
     3361 ggggtattgg ccgcctcacc caggcacctc cgctagccac ttatttgaag agctctactc
     3421 tctcctttga cctccaacct gacattgtaa ccccaaattc tccttcctag ggggctgcca
     3481 ctgtaggaaa ctggaccaaa caccgacttg ggggctttca cacctcaccc ccacctctag
     3541 tctgcatgga aattgtactg tgattccctt accctgcaaa tgactgcccc caactttggt
     3601 gtaaggtgtt tcctcgttca gcctgattgt ctcccacccc accccagcca atccccaacc
     3661 agcaataagg gtccaagcaa taagggcctc atatctacat tccttgcctc caaaatccca
     3721 tgccacccca aaggaaaccc tggactcccc gactttccac atactgtagc atctggtctc
     3781 catctctcac cttacctgtg gtggtttatg ggcatggtgg aatttttttt ttttttaaga
     3841 ttattataaa gcagtaaaac acaccaa
//
