LOCUS       NP_001159836             197 aa            linear   ROD 05-JUN-2024
DEFINITION  protein FAM219B isoform 1 [Mus musculus].
ACCESSION   NP_001159836
VERSION     NP_001159836.1
DBSOURCE    REFSEQ: accession NM_001166364.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 197)
  AUTHORS   Watahiki,A., Waki,K., Hayatsu,N., Shiraki,T., Kondo,S.,
            Nakamura,M., Sasaki,D., Arakawa,T., Kawai,J., Harbers,M.,
            Hayashizaki,Y. and Carninci,P.
  TITLE     Libraries enriched for alternatively spliced exons reveal splicing
            patterns in melanocytes and melanomas
  JOURNAL   Nat Methods 1 (3), 233-239 (2004)
   PUBMED   15782199
REFERENCE   2  (residues 1 to 197)
  AUTHORS   Zambrowicz,B.P., Abuin,A., Ramirez-Solis,R., Richter,L.J.,
            Piggott,J., BeltrandelRio,H., Buxton,E.C., Edwards,J., Finch,R.A.,
            Friddle,C.J., Gupta,A., Hansen,G., Hu,Y., Huang,W., Jaing,C.,
            Key,B.W. Jr., Kipp,P., Kohlhauff,B., Ma,Z.Q., Markesich,D.,
            Payne,R., Potter,D.G., Qian,N., Shaw,J., Schrick,J., Shi,Z.Z.,
            Sparks,M.J., Van Sligtenhorst,I., Vogel,P., Walke,W., Xu,N.,
            Zhu,Q., Person,C. and Sands,A.T.
  TITLE     Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap
            screen to identify potential targets for therapeutic intervention
  JOURNAL   Proc Natl Acad Sci U S A 100 (24), 14109-14114 (2003)
   PUBMED   14610273
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK028365.1, BC112403.1 and AV370547.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC111883.1, CJ178242.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..197
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 31.05 cM"
     Protein         1..197
                     /product="protein FAM219B isoform 1"
                     /note="uncharacterized protein C15orf17 homolog; protein
                     FAM219B"
                     /calculated_mol_wt=20875
     Region          1..77
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q14DQ1.1)"
     Site            14
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q5XKK7; propagated from
                     UniProtKB/Swiss-Prot (Q14DQ1.1)"
     Region          72..197
                     /region_name="FAM219A"
                     /note="Protein family FAM219A; pfam15260"
                     /db_xref="CDD:464600"
     Region          117..142
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q14DQ1.1)"
     Site            125
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q14DQ1.1)"
     Site            127
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q14DQ1.1)"
     CDS             1..197
                     /gene="Fam219b"
                     /gene_synonym="2310046O06Rik"
                     /coded_by="NM_001166364.1:94..687"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS52807.1"
                     /db_xref="GeneID:78323"
                     /db_xref="MGI:MGI:1925573"
ORIGIN      
        1 mateefrgha vrmstqgsqp gaapdsvagt aglpsgqsgg aglrlgerpp pamekrgpyl
       61 vtrapsiqak lkkhrdhaka vlrrkgmlga ltnrpdssgk rsvkfnkgyt alsqspdenl
      121 vsldsdsdge lesryssgys saeqvnqdvs rqllqdgyhl deipddedld lippkpiass
      181 acsccwcclg dssctlq
//
