LOCUS       NM_025912               3609 bp    mRNA    linear   ROD 10-AUG-2024
DEFINITION  Mus musculus family with sequence similarity 210, member B
            (Fam210b), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_025912
VERSION     NM_025912.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3609)
  AUTHORS   Xu,Y., Gao,R., Zhang,M., Zeng,Q., Zhu,G., Qiu,J., Su,W. and Wang,R.
  TITLE     Deletion of the Mitochondrial Membrane Protein Fam210b Is
            Associated with the Development of Systemic Lupus Erythematosus
  JOURNAL   Int J Mol Sci 25 (13), 7253 (2024)
   PUBMED   39000360
  REMARK    GeneRIF: Deletion of the Mitochondrial Membrane Protein Fam210b Is
            Associated with the Development of Systemic Lupus Erythematosus.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3609)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 3609)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3609)
  AUTHORS   Yien,Y.Y., Shi,J., Chen,C., Cheung,J.T.M., Grillo,A.S.,
            Shrestha,R., Li,L., Zhang,X., Kafina,M.D., Kingsley,P.D.,
            King,M.J., Ablain,J., Li,H., Zon,L.I., Palis,J., Burke,M.D.,
            Bauer,D.E., Orkin,S.H., Koehler,C.M., Phillips,J.D., Kaplan,J.,
            Ward,D.M., Lodish,H.F. and Paw,B.H.
  TITLE     FAM210B is an erythropoietin target and regulates erythroid heme
            synthesis by controlling mitochondrial iron import and
            ferrochelatase activity
  JOURNAL   J Biol Chem 293 (51), 19797-19811 (2018)
   PUBMED   30366982
  REMARK    GeneRIF: FAM210B is an erythropoietin target and regulates
            erythroid heme synthesis by controlling mitochondrial iron import
            and ferrochelatase activity
REFERENCE   5  (bases 1 to 3609)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   6  (bases 1 to 3609)
  AUTHORS   Elsen,G.E., Hodge,R.D., Bedogni,F., Daza,R.A., Nelson,B.R.,
            Shiba,N., Reiner,S.L. and Hevner,R.F.
  TITLE     The protomap is propagated to cortical plate neurons through an
            Eomes-dependent intermediate map
  JOURNAL   Proc Natl Acad Sci U S A 110 (10), 4081-4086 (2013)
   PUBMED   23431145
REFERENCE   7  (bases 1 to 3609)
  AUTHORS   Oeschger,F.M., Wang,W.Z., Lee,S., Garcia-Moreno,F., Goffinet,A.M.,
            Arbones,M.L., Rakic,S. and Molnar,Z.
  TITLE     Gene expression analysis of the embryonic subplate
  JOURNAL   Cereb Cortex 22 (6), 1343-1359 (2012)
   PUBMED   21862448
REFERENCE   8  (bases 1 to 3609)
  AUTHORS   Ayoub,A.E., Oh,S., Xie,Y., Leng,J., Cotney,J., Dominguez,M.H.,
            Noonan,J.P. and Rakic,P.
  TITLE     Transcriptional programs in transient embryonic zones of the
            cerebral cortex defined by high-resolution mRNA sequencing
  JOURNAL   Proc Natl Acad Sci U S A 108 (36), 14950-14955 (2011)
   PUBMED   21873192
REFERENCE   9  (bases 1 to 3609)
  AUTHORS   Tachikawa,K., Sasaki,S., Maeda,T. and Nakajima,K.
  TITLE     Identification of molecules preferentially expressed beneath the
            marginal zone in the developing cerebral cortex
  JOURNAL   Neurosci Res 60 (2), 135-146 (2008)
   PUBMED   18055048
REFERENCE   10 (bases 1 to 3609)
  AUTHORS   Narumiya,H., Hidaka,K., Shirai,M., Terami,H., Aburatani,H. and
            Morisaki,T.
  TITLE     Endocardiogenesis in embryoid bodies: novel markers identified by
            gene expression profiling
  JOURNAL   Biochem Biophys Res Commun 357 (4), 896-902 (2007)
   PUBMED   17462595
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK160529.1, AK149497.1 and AI504401.1.
            
            On Mar 13, 2009 this sequence version replaced NM_025912.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147935.1, AK148334.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-63                AK160529.1         2-64
            64-3598             AK149497.1         2-3536
            3599-3609           AI504401.1         1-11                c
FEATURES             Location/Qualifiers
     source          1..3609
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 94.83 cM"
     gene            1..3609
                     /gene="Fam210b"
                     /gene_synonym="2010011I20Rik"
                     /note="family with sequence similarity 210, member B"
                     /db_xref="GeneID:67017"
                     /db_xref="MGI:MGI:1914267"
     exon            1..271
                     /gene="Fam210b"
                     /gene_synonym="2010011I20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            272..441
                     /gene="Fam210b"
                     /gene_synonym="2010011I20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            442..3605
                     /gene="Fam210b"
                     /gene_synonym="2010011I20Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1726..1731
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam210b"
                     /gene_synonym="2010011I20Rik"
                     /note="hexamer: AATACA"
     polyA_site      1747
                     /gene="Fam210b"
                     /gene_synonym="2010011I20Rik"
                     /note="major polyA site"
     regulatory      3584..3589
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam210b"
                     /gene_synonym="2010011I20Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3605
                     /gene="Fam210b"
                     /gene_synonym="2010011I20Rik"
                     /note="major polyA site"
ORIGIN      
        1 gaggccccgg tctcggcccc gcccaccgcg ctgtgttgga gctgattccc gagtgggcac
       61 actggagctg cgctcgcggc gcgccatggc cgggctgttg acgctgcttg gcccggcagg
      121 aagagtgagc acccggctgc ggcccctggc cccttggctc ctgggaaccg ccacctcctg
      181 tgctccaccg ctctgggcct tagccttgtc ccatccggtt ccggacgccc gactgctgcg
      241 cacggcccgc ggggactgtc tcagccgcca ggagcccaac aggacccccg agccaggagg
      301 cagtgtcacc ggcacagaga aaaagctaag cagaacacag cagctgaaga aggttttcca
      361 agagtacggg gccgtgggcg tgtcaatgca cattgggatc tccctggtgt ccttggggat
      421 attttacaca gttgtttcca gtggcataga catgtctgca atcctgctta aacttggctt
      481 taaagagtcc ctggtgcagt ccaaaatggc agcaggcacc agcacattcg tggtggccta
      541 tgccatccat aagctgtttg ctcccgttcg gatcagcatc accttggtct ctgtgccctt
      601 tgtcgtcaga tacttccgca gcgttggact ctttaaacct ccagccacca agccttgacg
      661 ccagtctctt ctgatctgca agatttgggc tgtgtgcaag gtggctttct ttcctggtgg
      721 gggaagggag gggccgaggc taattgctac gttccctgtg ggttggtttt acttttatca
      781 tcaaacatct ggtgttttaa tttacttttt tttttaatgc tgttcctcat gtacatgact
      841 taaaaatgtc accaaggcat caaaatgagt tgacagccag gcctggtggt acaggccagt
      901 aaagccagct gctctggagg cggaggcagg aggatctcaa attcaagcct gcttaagcta
      961 cttatagttc agggtccgct taacaattta taagactgtg tcttgttcac cagtgagaga
     1021 gggctgaggt cattactcac ctggcacaga cggcctaaat gcaatcccca gcacaaaaag
     1081 agactgccta caaattgttc ctctagatca tcggggcaga ggtgctgtct ataaagcccc
     1141 cccgggggct aacctttgct cagattctta aaaagcagtg gttaatttgc tggcttttca
     1201 aaccctgccc gccctggttt gcctgcggtt taatatgcaa tattcagcag acagctgctg
     1261 gcgctacaat tagtgaggcg aaaataacca cgatccacat taccatcaag cccttgacat
     1321 tcgcagcact tgctgtgggg aaagcaggcc aagaacttgt catgtgcccc atccacttcg
     1381 aggctggatg ggatggggct ccaagtctga gatttcattg atactaggca atatggtttg
     1441 taaaatacag aaacactgcc caattgtgat gttgtcaatg ggctcctgat gcccatattc
     1501 tggggaacct tagatactgc catagaagct aaaagcaccc tagctttctt agacaatcca
     1561 cttagctatc tgaaacttga ggcattccag acctgacatg tttacaatgc accactgaac
     1621 ttttttaaat tgaattaatc agatgtatat ttgtaccact ttggggggtg gggggaggtt
     1681 gagaggaaaa tattgctcgt tctaactgta aagaaaccaa gaaataatac aagctgggga
     1741 aaagagatgt cttaattagg gtcctattgc tgtgatgaaa caaaatgacc aaactcacgg
     1801 ttccatacaa cacttcatca aacacaggga gggcaggcac ctggaggcag gagctgacag
     1861 cagaggccag agaggagagc cacttactgg cttgttcagc tgctttctta cagaacatag
     1921 cctgccagct catgggtgcc agtggttctc aacttgtgag ttgcaactcc tttgtcaaac
     1981 ctctagctca actcaaaaca gtagcaaaat taattgtgaa gtagcaatga aaataacctt
     2041 ctggttgggg gccaccatga ggaactgtac taaagggtgg cagcatgagg aaggttgggt
     2101 accgctggtg tagagggagg ttggaataga aagtcaagca gagactcaaa ctgaggcttc
     2161 ctcctccacg aagtcaggag cagacagagc aagaattggc tccagggctc aagcctgccc
     2221 tctgggcagc ctggcgtggg gacacttgtt ctgttctgtc atatccaaaa caaactccat
     2281 cccccccaag gcagcccaaa tatccagaaa cgggctcacc tggactatag aatttctgct
     2341 ggtcagataa agacagcatt cctcgggaac ccgtgaaact ggttctctct ctaccaaatg
     2401 gagtcattct ccttacttct ggcagaaggg tcatagctct cccagtagta gacctgtggt
     2461 acctaacggc gtatcagggc atgctggtat cacaagaccc tgatacacat ttcagtgttc
     2521 ctagcccttc ttgtcctccc taccctaaac tgcccccaac tcacaggctt cccgtccccc
     2581 agctgcctgt ccttataacc agctattctc tgtcctcttg gctcctggtc ctctctgtgc
     2641 tcgattctct atcctgtgcc agtttcctct ccgtctcacg gatcccccgg ccatgttcag
     2701 tccacccctc tctctctctc aacttcagat gcctctggct gttctcatgt ctataataag
     2761 aacctccccg caaccatacg aagtataacc atacatctat agttctcccc cggggagcta
     2821 gtgtttgaac tttgaagtct gctcagctgc atggtggaaa ggactgtgtt cttttttttc
     2881 ttgcacacaa ttcctttgaa attacattga cagccaggag acaaaggaga gaactgttaa
     2941 ctagcagaat gcattttata gagctctggc taaccgcctc ttagcccacg gttacccagt
     3001 catttgtctc agttaacatt taaaggagtt tttgtgagac aaattctcca ttgtgagatc
     3061 tctgaagtgg gattgtctta ttttccttag tacagcccac tgccaaaaag cttcctctga
     3121 tgtcaaatca ggatgtatta ccgaaactga ttccaaggac atccacatag ctgagccaag
     3181 atgctccagg ccagtggcag gtggactgga agaggcctct ccactgagcc tgtgttctgt
     3241 gcttcaggct ctggatcatc acccccgctg ctctcccatt ccggtaccta agtaacatct
     3301 atgcaaagaa acacattaaa agcagcaata aaactgctcc tacccacagc cacggatctt
     3361 ccaaacctag ccccgctctc aggcctctac ccagcagcca gaacacagca agagttgagg
     3421 tgaagcaact aaagcaccgt ataagccagc aaggcgcaca gagctgctcc tgcctatgtg
     3481 atctttaagt agaccaggag ccaggaaacc actttaagat gtaagccatt gtgtgtctct
     3541 agtttcttaa gcagaccaag tgaatggctt acagtctgaa acaaataaaa gcctttgtaa
     3601 aagtcaaaa
//
