LOCUS       NM_001081254            3187 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus family with sequence similarity 186, member B
            (Fam186b), mRNA.
ACCESSION   NM_001081254 XM_619361
VERSION     NM_001081254.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3187)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3187)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. PMID: 29144450]
REFERENCE   3  (bases 1 to 3187)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from AC161198.5.
            
            On Feb 6, 2007 this sequence version replaced XM_619361.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849379
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-236               AC161198.5         199092-199327       c
            237-462             AC161198.5         197587-197812       c
            463-642             AC161198.5         195961-196140       c
            643-2266            AC161198.5         191465-193088       c
            2267-2459           AC161198.5         190836-191028       c
            2460-2629           AC161198.5         186637-186806       c
            2630-2815           AC161198.5         185837-186022       c
            2816-3187           AC161198.5         183165-183536       c
FEATURES             Location/Qualifiers
     source          1..3187
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 56.11 cM"
     gene            1..3187
                     /gene="Fam186b"
                     /gene_synonym="EG545136"
                     /note="family with sequence similarity 186, member B"
                     /db_xref="GeneID:545136"
                     /db_xref="MGI:MGI:3647604"
     exon            1..236
                     /gene="Fam186b"
                     /gene_synonym="EG545136"
                     /inference="alignment:Splign:2.1.0"
     exon            237..462
                     /gene="Fam186b"
                     /gene_synonym="EG545136"
                     /inference="alignment:Splign:2.1.0"
     exon            463..642
                     /gene="Fam186b"
                     /gene_synonym="EG545136"
                     /inference="alignment:Splign:2.1.0"
     exon            643..2266
                     /gene="Fam186b"
                     /gene_synonym="EG545136"
                     /inference="alignment:Splign:2.1.0"
     exon            2267..2459
                     /gene="Fam186b"
                     /gene_synonym="EG545136"
                     /inference="alignment:Splign:2.1.0"
     exon            2460..2629
                     /gene="Fam186b"
                     /gene_synonym="EG545136"
                     /inference="alignment:Splign:2.1.0"
     exon            2630..2815
                     /gene="Fam186b"
                     /gene_synonym="EG545136"
                     /inference="alignment:Splign:2.1.0"
     exon            2816..3187
                     /gene="Fam186b"
                     /gene_synonym="EG545136"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3166..3171
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam186b"
                     /gene_synonym="EG545136"
                     /note="hexamer: AATAAA"
     polyA_site      3186
                     /gene="Fam186b"
                     /gene_synonym="EG545136"
                     /note="major polyA site"
ORIGIN      
        1 agttactaga ggagctgtgg ccgggcagag ggtacccagg aacctccctg ggcccttagc
       61 ccctaaagct gcccatactg tgtgttcagc cctgtgtaca agagccatgg gacatcttcg
      121 gactgagaga attatctaga atggagaagg acaacccccc acacttggtg actcccacat
      181 cagtgaaggc tattatctca aagattgaga ctgcccagct aattcggact caggaggata
      241 tttccaccca gctctcggac atcttggaca atgtcaactg tgccatcaac cgcttccagg
      301 aagaactggg atatgactta aaagaaagag cgaagcctca ccaaccagag cagaaaggca
      361 agaagaggtt catcttgctg gagaaactcg ccgccttctc tgatgacgcc aaggccaagg
      421 agaagcacct gtatgagatc ctccactggc tgggcgaatg gggtgacagt ctgacttatg
      481 agataaagga caggagttcg gaggaagacg aagccctaga cgaatggatc gaagtgatgg
      541 agaaggtgtt gcctctttcc ctcatggcca ccaaaggagg catcgagtct ctcatctctc
      601 tgtgctcgac tctcatcgaa gaccagaaga aaatgacaca aaggtacaaa cataacttct
      661 ggcaggactg gcatgagaag agcccacaga ataaggagca gggaatccct gtgccaccga
      721 gcccggagca gatgctccag gacaagaaca ccgcccacct gaacgtctcg gaggtcaggt
      781 ccatgctaca ggagctcctg gactccacga tgttcaacaa aggggaggtt aaagccatca
      841 ggtacatgtc cgccgtggtg gagaacctca acaaggcctt gaccctccag cacaaggaga
      901 acaagagtct ggagacaaag tacaagtacc tgcaggtgga aaagaacaaa gagctcagca
      961 cccagaggct gcacttccaa aaatccatcc aagtcctgga gagcaaaagg gacgcgctgc
     1021 tgaaacaggt aaagattcta ggggacaaat accatcacct cctcatgtta aagcacaccc
     1081 tggagttcca gctgaatata gcccagcctg ctagtggtcc agaagaaccc accaagcatt
     1141 tcattcatta cctggaaccc cctgaaaaag agccccttcc agggcagggt acagccctgg
     1201 agaaggagaa gcaggagccc aaggagaaag gacaggcagt ttcagctctc ttttcaagtc
     1261 ccctgaccaa ggcctggcac agtggcacta cacctgcagc cccaaagcca atcttcggca
     1321 cggacacgga ttcgagggtg agggatgtgt tcgttgaccg cacagaggcc ctggagcctg
     1381 tgctgctgca ctcagaggtc ccccagattc ccacacaatg ggagaaacta ggggacatga
     1441 aagacaaaga ccagggggat cacatccaag aggagggagc ccaaagcaag tccctgtccc
     1501 cagggagcat caggaggagg cttctggaga gccacatggg gcactgggag gaagagctca
     1561 actgggagac cagaaggcag caatggctgc aggaggaaga gatgtggctt cagcggcaga
     1621 agaagtgggc cctgctggag caggagcacc aggaaaaggt gaggcagtgg gaggcagagg
     1681 cggctgccag gcagcagtgg cagaggctca cccagccaga ggaggagaag cccagcccca
     1741 ggaaggagca gaaggcaagc tcggagatga tcttcaccac caccagtcgg tggaagagcc
     1801 tgaagaagtc ggagtccacg ccgacgcccc actgcagggc ccagtccgcg catcagagca
     1861 ggtcgtacat actcgcatcc ccacacaccc agcagcctgg gcaggggacc cagaggaccc
     1921 tgggttcagc tgagtttctg caaaggccac cgacccgcca ggtttctgcg aagcccaaga
     1981 aatccacctc cttgccagtc actgggacgt ccatcctccg aagggtgtcc caggtctctc
     2041 tgcagcaagc cccggggaca cctaaggaca aggtctacca catagacatg gaggcccagc
     2101 tgaagaacct gcaggtcctg ggcggttcgg agtcagaggt ggcactgcca cagtacctgc
     2161 gcagcaaagc cctggaggtc attgccatcg ccatggacct gagcattctc cggctgcagt
     2221 acctatgcaa gaagtatatc caatacaggc gcttccagag cctccgacta gaaatgatca
     2281 aacacatagg agccattcga caaacaagag ttaccagtaa ggcccagaac ctctatctgt
     2341 tcctggagaa cattgaccac cagcagagcc tcaggctgca ggcctgggca gacaagcaga
     2401 gagacctgga ggaaaggcac caggaatgcc tgcacaccat ggtggccatg ttccctaagc
     2461 tccagcaaga gtggaacgtc cacctgagcg tccccgtgct cacccatgtg aagccagtga
     2521 agagcaagtc atcttcagtc ttgcttcaga gagtccgctc cagccactcc accaccaagc
     2581 accgtcctcc acctaagccc cgggagtctg tgcccctgcc gataactggc caacaaggga
     2641 gccagatgga agccatatgg aaggctgatg tggcctcttc gagtcacccc atagaaaaga
     2701 agacccctac aaacatgtgc tgggaacaac tagggggcta cccagacatc cccaggttac
     2761 tggtggtgga cgagcatccc tcctgcccca gaagctcggt gtccttcaag gctcgctctt
     2821 tcagtgcttc ctcggtccaa aggaaggaag gccaggaacc ctcagaggag ctagctgggc
     2881 ctgtctgcaa aatgtccagc cagtcactac ccggatcgat ctgtacaaag caggaaggat
     2941 cgggcagctc cagtacccac tccatccctt agttagcgac tctcaaactt ctgggccact
     3001 agcaactgca cagcggcttg ttctaatcct aaccctaacc caattcggga tcccagctgg
     3061 tgctcttaaa cacacacagt tgttgcgaag ttgttccaga actttgggaa actctatttt
     3121 cttttctttt cttttttcag tccccaaact attagtttgt aataaaataa aggttggttt
     3181 attttat
//
