LOCUS       NM_001081161            4149 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus family with sequence similarity 171, member A1
            (Fam171a1), transcript variant 1, mRNA.
ACCESSION   NM_001081161 XM_194000
VERSION     NM_001081161.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4149)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928883.19.
            
            On Mar 19, 2018 this sequence version replaced NM_001081161.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC138175.1, SRR7652917.1000588.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-271               AL928883.19        35654-35924
            272-499             AL928883.19        95508-95735
            500-592             AL928883.19        103695-103787
            593-751             AL928883.19        114549-114707
            752-928             AL928883.19        119817-119993
            929-1045            AL928883.19        137525-137641
            1046-1160           AL928883.19        140742-140856
            1161-4149           AL928883.19        142090-145078
FEATURES             Location/Qualifiers
     source          1..4149
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 1.73 cM"
     gene            1..4149
                     /gene="Fam171a1"
                     /gene_synonym="9630050M13Rik"
                     /note="family with sequence similarity 171, member A1"
                     /db_xref="GeneID:269233"
                     /db_xref="MGI:MGI:2442917"
     exon            1..271
                     /gene="Fam171a1"
                     /gene_synonym="9630050M13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             175..2853
                     /gene="Fam171a1"
                     /gene_synonym="9630050M13Rik"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="protein FAM171A1 isoform 1"
                     /protein_id="NP_001074630.1"
                     /db_xref="CCDS:CCDS38036.1"
                     /db_xref="GeneID:269233"
                     /db_xref="MGI:MGI:2442917"
                     /translation="MSKSAALLLCLLGCHVWKAVTKTLQEPGAGAQEVTLKVHISDAS
                     THQPIADALIEIFASQVSVASGTSGTDGVAFIKFPYKLGNQLIVTATKQAYVPNSAPW
                     KPIRLPVFSSLSLGLLPERSATLMVYEDVVQIVSGFQGARPQPRVHFQRRALRLPENT
                     SYSDLTAFLTAASSPSEVDSFPYLRGLDGNGTGNSTRYDLTPVTAVSVHLLSGNGMPV
                     LVDGPIYVTVPLATQSSLRHNAYVAAWRFDQKLGTWLKSGLGLVHQEGSQLTWTYIAP
                     QLGYWVAAMSPPIPGPVMTQDITTYHTVFLLAILGGMAFILLVLLCLLLYYCRRKCLK
                     PRQHHRKLQLPPALESSKRDQATSMSHINLLFSRRASDYPGPLSVSSHSRPEAPGTKE
                     LMGGVHLEMMSPKGEGDLHTPMLKLSYSTSQEFSSREELLSHKEEDKSQTSFDNLTPS
                     GTLGKDYHKSVEIFPLKARKSMEKEDYEAPGNDDYRGSYNTVLSQSLFEKQDQEGLAS
                     AGSKLTIQEHMYHVPLSPEKEQLLDRRPTECMMSRSVDHLERPTSFPRPGQLICCSSV
                     DQVNDSVYRKVLPALVIPAHYMKLPGDHSYVSQPLVVPADQQLEIGRLQAELSNPHAG
                     IFPHPSSQIQGQPLSSQAISQQHLQEAGAREWSSQSASMSESLSIPASLNDAALAQMN
                     SEVQLLTEKALMELGGGKPLPHPRAWFVSLDGRSNAHVRHSYIDLQRAGRNGSNDASL
                     DSGVDMNEPKSARKGRGDPLSLQQSHTPLQEHQQKDPRAPDSTACTQLLYLEDMDPSG
                     SECAATVCTPEDSALRCLLEGSGRRSGGQLPSLQEETTKRTSDVPLEPLASPNQRRSA
                     NDEDEDDDDDDDDQGEDKKSPWQKREERPLMAFNIK"
     exon            272..499
                     /gene="Fam171a1"
                     /gene_synonym="9630050M13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            500..592
                     /gene="Fam171a1"
                     /gene_synonym="9630050M13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            593..751
                     /gene="Fam171a1"
                     /gene_synonym="9630050M13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            752..928
                     /gene="Fam171a1"
                     /gene_synonym="9630050M13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1045
                     /gene="Fam171a1"
                     /gene_synonym="9630050M13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1046..1160
                     /gene="Fam171a1"
                     /gene_synonym="9630050M13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..4149
                     /gene="Fam171a1"
                     /gene_synonym="9630050M13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4125..4130
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam171a1"
                     /gene_synonym="9630050M13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4149
                     /gene="Fam171a1"
                     /gene_synonym="9630050M13Rik"
                     /note="major polyA site"
ORIGIN      
        1 tggggaagcc gggcgcgggg ctcggaggag ggagcggccg gctgcggggc cccggccaat
       61 cgggcggctg gccgggcgcg cggagccaca gcgccatgga gggaggcgcg gcgcccggcc
      121 gcccgtgacc gagcgtggcg agcccgagag gcccgcggcg cccgtggcgc ggagatgagc
      181 aagtccgctg cgctgctgct ctgcctgctc ggctgccacg tttggaaggc agtcaccaag
      241 acgctgcagg agcccggcgc gggagcccaa gaggtgacct tgaaggtgca cattagtgac
      301 gccagcaccc accagcccat cgcagatgcg ctcattgaga tcttcgccag ccaggtgtct
      361 gttgcctctg gcacatctgg cacagatggg gttgctttca tcaagttccc atacaagctt
      421 ggaaatcagc tgattgtcac tgccacaaaa caggcctacg tgccaaactc tgccccgtgg
      481 aagcccatcc gattaccggt gttttcctca ctgagccttg gcctgcttcc tgaacgctcc
      541 gctacgctga tggtctatga agatgtcgtc caaatagtct caggattcca aggtgcccgg
      601 ccacagcctc gagttcattt ccagagaagg gccttgaggt tgccggagaa caccagctac
      661 agcgacctaa cagcgttcct cactgcggcc agctccccat cagaagtgga cagcttccct
      721 tacttgcgag gattggatgg aaacgggaca ggaaacagca ccaggtatga cttgactcct
      781 gtcacagccg tcagcgtgca cttgctcagc ggtaatggga tgccggtgct ggtggacgga
      841 cccatctatg tcactgtgcc cttggccact cagagcagtc tgaggcacaa tgcctatgtc
      901 gcagcatggc ggtttgacca gaagctggga acgtggctga agagtggtct gggcctggtg
      961 caccaggaag gcagtcagct cacgtggacg tacattgctc cccagctggg gtactgggtg
     1021 gcagccatgt ctccccccat cccaggtccc gttatgacac aggacattac cacgtatcac
     1081 acggtgtttc ttttggccat tttaggagga atggctttca ttcttttggt tttgctgtgt
     1141 ctccttttat attattgcag gaggaagtgc ttgaaacccc gccagcatca cagaaagctg
     1201 caactgcccc cagctctgga gagctccaag agggatcagg caacatccat gtctcacatc
     1261 aacttgctgt tttctcgacg agcatcagat tatcctgggc ctctgtctgt ctccagccat
     1321 agccgcccag aggccccagg gacaaaggag ttgatgggcg gggtgcattt agaaatgatg
     1381 tcccccaaag gggaggggga cctgcacaca cccatgctga agctctccta tagtacctca
     1441 caagaattta gctcccggga ggagctgctg tcccacaaag aagaggataa aagccaaaca
     1501 tcttttgata acttaacgcc aagtgggaca ctggggaaag actaccataa gtctgtggag
     1561 atttttccct taaaggcaag aaaatctatg gaaaaagaag actacgaggc ccctggcaat
     1621 gatgactaca gaggtagtta caataccgtg ctctcccagt ctttgtttga aaagcaagat
     1681 caagaaggcc tggcatcagc aggaagcaaa ctcactattc aggaacacat gtaccatgta
     1741 cctttatcgc ctgagaaaga gcaactgctg gaccgcagac cgactgaatg tatgatgtca
     1801 cgatctgtcg atcacctgga gagacctact tccttcccga ggccaggcca gttgatctgc
     1861 tgtagttctg tggaccaagt caatgacagc gtttacagga aagtattgcc tgccttggtc
     1921 attccagctc attatatgaa acttccaggg gaccactcgt atgtgagcca gcctctggtg
     1981 gtcccggctg accagcagct ggaaatagga aggctccagg ccgagctgtc caacccccat
     2041 gcagggatct tcccacaccc atcctctcag atccaaggcc agcctttgtc ttcccaggct
     2101 atctctcagc agcacctaca ggaagcaggt gcacgggagt ggagctctca gagtgcatcc
     2161 atgtcagagt cactgtctat ccctgcatcc ctgaatgatg cagctttggc tcaaatgaac
     2221 agcgaggtgc agctcctcac cgaaaaggca ctgatggaac ttgggggtgg aaagccactt
     2281 ccacaccctc gggcatggtt tgtctcccta gatggaaggt ccaacgctca cgttagacac
     2341 tcatacattg atctccaaag agctggaagg aacggaagta atgatgccag tttggactct
     2401 ggtgtggata tgaatgaacc aaaatctgcc cggaagggaa ggggagaccc tttgtctctc
     2461 cagcagagcc acacacctct gcaggagcac cagcaaaaag atcccagagc tcccgacagc
     2521 actgcctgca cgcagctcct gtaccttgag gacatggacc cgagcggcag tgagtgtgca
     2581 gccacggtct gcacccccga ggacagtgca ctgcgatgct tgttggaagg gtcaggtcgg
     2641 aggagtggcg ggcagctgcc cagcctgcag gaagagacaa ccaaacgaac ttcagacgtt
     2701 cccctggagc cattagccag tcccaaccag agaagatccg ccaatgatga agatgaagat
     2761 gacgatgacg atgacgatga ccaaggagaa gataagaaaa gcccctggca gaaacgagag
     2821 gaaaggccct tgatggcctt caacatcaaa tgagccatcg ataagcccct aaaatgcgga
     2881 ttataaaatt gccaaatatc ctttctcatg gaagtgcata cctgcgtgtg gagaagctga
     2941 ggagtgaaaa ccatgcaagt agatgcttac tgccttgaca tgggaattac ggttatgaca
     3001 gaacgaaagg tgactgacag gtgctgcccc tccgagaagg tggctgcgag acatgtcatt
     3061 ctacggacct gacttgtcac agtagagatg ctgacaaacc acatgtggga ttgctatgct
     3121 ccaaggatca cctcagttct ctctcagatt ctggaaacag atgaaatgct ctttgcattg
     3181 tctgaaccct ctctaattct atcatgataa cgctactgtg acgctctcac tgggaagctg
     3241 ggtggcgaga actttctgga cgtcgatgtt atctcaaagg aaagctatgc attgctgctt
     3301 ctttgttacc ttgcttatgc tttgctttaa ttaggcctct ctctctccct ctctctctct
     3361 ctctttctct ctctctctct ctctctctct ctttctctct ccacacacac acatagggtg
     3421 ttgggttttt tctctttctt taaagtatga ttcagtttca gttgtaaacg ttttgcttcc
     3481 ttcagttcta cttctctgtg gttggtttcg gtgtcgccct tcaggaactc agaacccggg
     3541 tgtcagctct taacatctct aagcctttta ataaaactgt actgaagttt ttatcagcta
     3601 agagtcagtt cttcaattct ggtcccatta tctccaagtg ccttttttac agtgacaaca
     3661 gacagtccct cggtttcatg tcttttcgta accctttcaa ttgaactgcc tggattttat
     3721 ataaagttac taaacgatac cttgttcttg gaactgcatg ctgccaagtg ccattcgtac
     3781 tgagcatcct catttcaacg cagtatacgc tctagttatc atgtgtaacg tgggtctgtt
     3841 tagctgagat agactagagg aggacactag agatgcccat tcctactccc tccctttggt
     3901 cactagccac cattatggtt ccactggctg tttgtatata gggttatgta ttaactctag
     3961 aatcccgtgt gcccttcttg ctcaccgaac gtgagagtat gggctgagca gggggattga
     4021 atgtgactgt taaaaacact catgtactgt ccaaaagtgc cagaatgact cttctgcgca
     4081 ttctccttta agagctgctt ggttgtccaa aaatgaaaac tcaaaataaa cttggaagaa
     4141 ggaaaaaaa
//
