LOCUS       NM_001403152            5035 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus family with sequence similarity 168, member B
            (Fam168b), transcript variant 4, mRNA.
ACCESSION   NM_001403152 XM_006495845
VERSION     NM_001403152.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5035)
  AUTHORS   Mishra,M., Akatsu,H. and Heese,K.
  TITLE     The novel protein MANI modulates neurogenesis and neurite-cone
            growth
  JOURNAL   J Cell Mol Med 15 (8), 1713-1725 (2011)
   PUBMED   20716133
REFERENCE   2  (bases 1 to 5035)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
REFERENCE   3  (bases 1 to 5035)
  AUTHORS   Powles,N., Babbs,C., Ficker,M., Schimmang,T. and Maconochie,M.
  TITLE     Identification and analysis of genes from the mouse otic vesicle
            and their association with developmental subprocesses through in
            situ hybridization
  JOURNAL   Dev Biol 268 (1), 24-38 (2004)
   PUBMED   15031102
REFERENCE   4  (bases 1 to 5035)
  AUTHORS   Thuret,S., Bhatt,L., O'Leary,D.D. and Simon,H.H.
  TITLE     Identification and developmental analysis of genes expressed by
            dopaminergic neurons of the substantia nigra pars compacta
  JOURNAL   Mol Cell Neurosci 25 (3), 394-405 (2004)
   PUBMED   15033168
REFERENCE   5  (bases 1 to 5035)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   6  (bases 1 to 5035)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC107738.16.
            
            On Mar 28, 2022 this sequence version replaced XM_006495845.3.
            
            Transcript Variant: This variant (4) represents the longest
            transcript and encodes the longest isoform (4).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219382.126716.1,
                                           SRR13422598.286780.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-186               AC107738.16        96984-97169         c
            187-267             AC107738.16        90889-90969         c
            268-348             AC107738.16        82923-83003         c
            349-384             AC107738.16        78176-78211         c
            385-527             AC107738.16        74023-74165         c
            528-726             AC107738.16        73748-73946         c
            727-856             AC107738.16        72153-72282         c
            857-5035            AC107738.16        67382-71560         c
FEATURES             Location/Qualifiers
     source          1..5035
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 13.34 cM"
     gene            1..5035
                     /gene="Fam168b"
                     /gene_synonym="Mani; mKIAA4042"
                     /note="family with sequence similarity 168, member B"
                     /db_xref="GeneID:214469"
                     /db_xref="MGI:MGI:2448487"
     exon            1..186
                     /gene="Fam168b"
                     /gene_synonym="Mani; mKIAA4042"
                     /inference="alignment:Splign:2.1.0"
     exon            187..267
                     /gene="Fam168b"
                     /gene_synonym="Mani; mKIAA4042"
                     /inference="alignment:Splign:2.1.0"
     CDS             198..839
                     /gene="Fam168b"
                     /gene_synonym="Mani; mKIAA4042"
                     /note="isoform 4 is encoded by transcript variant 4;
                     protein FAM168B; myelin-associated neurite-outgrowth
                     inhibitor"
                     /codon_start=1
                     /product="myelin-associated neurite-outgrowth inhibitor
                     isoform 4"
                     /protein_id="NP_001390081.1"
                     /db_xref="GeneID:214469"
                     /db_xref="MGI:MGI:2448487"
                     /translation="MNPVYSPGSSGVPYANAKGIGYPAGFPVGYAAAPAYSPNMYPGA
                     NPTFQTVLEIEPRVLHMLGYTPGTPYKVSCSPTSGAVPPYSSSPNPYQTAVYPVRSAY
                     PQQSPYAQLSLFSPQQGTYYTQPLYAAPPHVIHHTTVVQPNGMPATVYPAPIPPPRGS
                     GVTMGMVAGTTMAMSAGTLLTAHSPTPVAPHPVTVPTYRAPGTPTYSYVPPQW"
     exon            268..348
                     /gene="Fam168b"
                     /gene_synonym="Mani; mKIAA4042"
                     /inference="alignment:Splign:2.1.0"
     exon            349..384
                     /gene="Fam168b"
                     /gene_synonym="Mani; mKIAA4042"
                     /inference="alignment:Splign:2.1.0"
     exon            385..527
                     /gene="Fam168b"
                     /gene_synonym="Mani; mKIAA4042"
                     /inference="alignment:Splign:2.1.0"
     exon            528..726
                     /gene="Fam168b"
                     /gene_synonym="Mani; mKIAA4042"
                     /inference="alignment:Splign:2.1.0"
     exon            727..856
                     /gene="Fam168b"
                     /gene_synonym="Mani; mKIAA4042"
                     /inference="alignment:Splign:2.1.0"
     exon            857..5035
                     /gene="Fam168b"
                     /gene_synonym="Mani; mKIAA4042"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5013..5018
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam168b"
                     /gene_synonym="Mani; mKIAA4042"
                     /note="hexamer: AATAAA"
     polyA_site      5035
                     /gene="Fam168b"
                     /gene_synonym="Mani; mKIAA4042"
                     /note="major polyA site"
ORIGIN      
        1 gtgggctgcg gtgtctgcgc agcgtcggcg ggagcggggg ccgcggcgag gctggcgggc
       61 gggcgggagg cagcgcgggc ctagcggtcg gccgcaaccg agcgtcgtct gggcactgcc
      121 cgtcgccgag ccccacgccg tgccggctcg ggccggcgcg cgccggtccc ggaggctcag
      181 gccaccttct tgaaatcatg aatcctgttt atagccctgg gtcttctggc gttccctatg
      241 caaatgccaa aggaattgga tatccagctg gttttcctgt gggctatgca gcagcacctg
      301 cctattctcc taacatgtac cctggagcga atcctacctt ccaaacagtg ctggagattg
      361 aacccagggt cttgcacatg ttaggctaca ctcctggcac accttacaaa gtgtcctgtt
      421 ccccaaccag cggagctgtt ccaccatact cctcttcccc caatccttac cagacggctg
      481 tgtacccagt gagaagtgcc tacccccagc agagtccata cgcccagttg tctctgtttt
      541 ccccacagca aggcacgtac tacacacaac ctctgtatgc agcacctcct cacgtcattc
      601 accacaccac ggtggtgcag cccaatggca tgccagcaac agtctaccct gctcccatcc
      661 ctcctcctag aggcagcggg gtcaccatgg gcatggttgc tgggaccacg atggccatgt
      721 cagcaggtac tctgctgact gctcattctc caactcctgt agcccctcac ccggtcactg
      781 tccccacata ccgagcccca ggaacaccca cctacagcta tgtgccccca cagtggtgat
      841 tgccctgcaa attaatattt gaggatggag ctgtgcagtc acttcattga gttccacagc
      901 tggtgctgca ggccttgtgc ctccaaccag gactttcttc ttactgctcc gacacttagc
      961 taaacatgac tgcgccccag cccagcaggt cccagctcgc tagtctccaa ctaactctgg
     1021 gttggtttta aagcaaatcc tgttttgtgg actgcctggc aaatttttta gctaactgta
     1081 atgataaaaa gggagtatta ctctattctg aatcatatct agttgaatgc atgtttataa
     1141 aaacaaacaa aaacaaagct tgctcaatct acctgcagtg actgatgcaa aaccatcata
     1201 tgcaaaaccc gaaggactgg accacgttca cagcctgtcc tgtccctcac gcacctctgc
     1261 gatgtacgct gagcctcagt tacacttgta caagggatgt cctcactgaa gcgtggggag
     1321 gactgcaggg gactcttagg ggctggggtt gccagttatg gacacagact atagctttca
     1381 gcagcctggt tttttggcac tggctgactg atcctgaggg agctgcaggg actgggggag
     1441 agagagcaca cctgcagcag ctccagacag cagcagcagc agcagcaggg atgacggggt
     1501 ccctctcctt catttcagct ggagtgtgct ctgcagaaca ggggtctacc tgaagcttat
     1561 caggaaatac aggagcttgg tgacgagtcc agctggggtg aggagtggtc tgtgtgtcag
     1621 agcagggtct gccatccgag ttttctctgt atgtcttaca ggataacgtt ctctgtatct
     1681 gttgggactg ttgggaaagt ccattgtaga agtaaactgt cttcctagga gggaagatgt
     1741 caaagagaag cagccacact gaggcagtgt tgtcttttgc tttattttgc ttagggaacc
     1801 attccttttt ttccccctga gaataactga gtcacctaaa gacatgggca ctgctgtatt
     1861 ctcccacaaa gacttcagct gtgtgctgtg aagagtgttg tacatttaag actggttaca
     1921 agggaataag tgtattttta agttagttcc tcatgtttct tgtagagaag cagggctgtg
     1981 atgatgtgta aaaatgtaga aataatgtag cttgtcttgg ggccattcac ctgaggatgc
     2041 tctctgtaac tagcggggtg aggcccggga agcctgcgga aacctgcgga agccactctg
     2101 ctgtcactga aggcactcag taccaagcag atgtggaaag cagaaagggc caggcagttc
     2161 aggagtgctc ttgcttggaa ggctctgtgg tgggaaagat tttgagtgtg tacataagaa
     2221 accacaaaag ttctttctgc ctgagtgtgc ccgacttgaa tctgtgagag tgtttctgtt
     2281 cagtgtgggt caaagggcag ggcacgagga cctctctggg ctctgtcaac tgggggtgag
     2341 ctttgtatct tttgtcagcc ccattgaatt cctggggctt tggttggaag gggtgcttgt
     2401 ctctggcagc taagtcaggg cttccatgtt ggtgtagagg ttgcctcagt agcagtcaac
     2461 ttggctagag gctgggtcac ctgaatatgg aaccttcggt gaccttattt ttatagtaat
     2521 gctctccata gttttttttt aagcatttta ttttttgaga agtttaggaa ggttgctgca
     2581 tggatcagtg tgaacagaag attcctcatt ccttatgtct atgaacatag aaagtttatg
     2641 gatgattatg gttaattgcc tcatgagcac ttaggtgtgt gtgtgtgtgt atgtgtgcgt
     2701 gcgtgcgtgc gtgtgtgtgt gtgtgcttgg atgtgcgcgt gcatggggag aggggtagca
     2761 ccagcaagca caccctgcac agagatagac acgcttgctg gagcacacag cctgcacccg
     2821 tacttccatg ttgggatccc gtccctgtgc tgagtgactt gcagggttgg gatttccaag
     2881 ttttctctgg actcatcaga cagaagggga tttctttaga acaaatgtac ctgtgatttt
     2941 cacgtgtttg aaaaagtccc cttatccatc cccaactaaa catggctatc tccctgcctg
     3001 gaaagggtag agttgtttgc ctacagcagg aagttaccaa gtctttgagc ctacttgcag
     3061 caacacacag tgtgtgtgta tgcacaggcc ctgagttctc aagagagagg gaggggctgc
     3121 tgccctcctg ctgatcacat cagcctcaca cacttgccct ggaactgttg aaatggagtg
     3181 actaccaaac acctctgtag tgtacaactc ggctgggtgg aaatcttgtc tgttttgaag
     3241 ctatcaggtc atcactgtgg gatctgctgg tgagagagct taccaggtga aaatctgggt
     3301 atatggatgg tagtgaactg tcacaggggg tgactttaac aacattcagt ttcagtaaaa
     3361 ataaggaaca gaattgggtc agtattctac tacatggctg tacaggtatc ccaaaacatt
     3421 gaggaacatt ccaagacagt gtgctttcta tgagtgtgac attcctgact agagtccttc
     3481 agctgaattg acaggcaggc agagagtctg atccctatgg acactgacat cgttgttaag
     3541 gagatatata gatatatcta tatatatcaa gtttattttc tgctgccgtc cctgaggcta
     3601 ggggccttcc ttcctcggct gctgctgctt gcagtttaga gttgtggagt attggaaact
     3661 gtaagctcct tgactctgga gaagcaaacc caccaccatc aggattgggt cagttaggct
     3721 acaggcatgg aagcggcctc tgcaactgtt gtctctgtgt tgtggtcttc cttggaggaa
     3781 ctgttgagtg gctgttggct accagttgcc atcctgagta gcagcttgtg agtgttttgc
     3841 attggttgtt gagtgtctac tgttcctcgg ccatgcacct ggcatggttt gttgtttgat
     3901 gggacaggag gctggagaag cagactgggt gttttacagt ccggtgagag gaaagtcagt
     3961 ctccgggagg gggaggcttg agctccctgc cttctcattg gccctctgag tgtgtctgtg
     4021 gttgggagag gttggcaagc accagcttta cacattgggg ctgcctcaga tttccttagt
     4081 tctccttctg aatattggag tttagtatta ctgtggggcc accttctctc agcagctggc
     4141 atctgtactt gtggtatatc tggcactgcc aagtggtgca ggacctccca gggtgcagtg
     4201 gcaagtgtgg cagctactgg tcctttcctc tggtgctttc tgagggttgc agagggcagg
     4261 tgtgcagtag agcttcctct cgtgtcctgc tcacctccca gggttttaca ttttctgagt
     4321 tgcttactcc tgccctgtct tctgtgtttg gtggagtgat gatgtggtct cagtaggaac
     4381 ggtaacattg cttcgccgtg tcttaaagga gtcttctctt ccctagccct ccctgttcat
     4441 gtgaagaaca gaaagcctgc agagtaaatc tgactagaat catggcatgg gaggcagcag
     4501 cttttctgtc caaggactgc agtagctgct catgagctgt gaggacctgg tgggtataca
     4561 ggcagttccc agggagggca gtgggtacgt ctggtgcaga ccgtgggcag tgtatagagc
     4621 agttgggaca gactgggggc tggctcccag cagggttact gtggcagctg gaggccccaa
     4681 ggagcctgct aggctgtgac ggaacagaaa aggttcttcg tttttaaact tttgttttta
     4741 aatactcttt tttacactgt tgttggtact ttttttatgc ttaagtcagc attgtcttcc
     4801 agtgttaaag gcatcccttg cctcttcatg gaacttatgt gtcaaaacaa aggaacgggc
     4861 agactgtcca tcccaagcca gttcaattag atgtaaattc atactgtttt aattttttat
     4921 gcaatctgat gagtagatgg gctcagattt aaaatcctta aaagcacgtt tattgtaacc
     4981 agaattgtta tgtaattaat actgcagttt tcaataaaga ttgacttgtg ttgca
//
