LOCUS       NM_001362169            6653 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus family with sequence similarity 168, member A
            (Fam168a), transcript variant 1, mRNA.
ACCESSION   NM_001362169 XM_006507919
VERSION     NM_001362169.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6653)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6653)
  AUTHORS   Boon,A.C., deBeauchamp,J., Hollmann,A., Luke,J., Kotb,M., Rowe,S.,
            Finkelstein,D., Neale,G., Lu,L., Williams,R.W. and Webby,R.J.
  TITLE     Host genetic variation affects resistance to infection with a
            highly pathogenic H5N1 influenza A virus in mice
  JOURNAL   J Virol 83 (20), 10417-10426 (2009)
   PUBMED   19706712
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ101582.1, AK043083.1 and BC079886.1.
            
            On Apr 6, 2018 this sequence version replaced XM_006507919.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK122235.1, SRR1660821.136359.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-49                CJ101582.1         1-49
            50-1493             AK043083.1         2-1445
            1494-6653           BC079886.1         1440-6599
FEATURES             Location/Qualifiers
     source          1..6653
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 54.39 cM"
     gene            1..6653
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
                     /note="family with sequence similarity 168, member A"
                     /db_xref="GeneID:319604"
                     /db_xref="MGI:MGI:2442372"
     exon            1..259
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
                     /inference="alignment:Splign:2.1.0"
     exon            260..347
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
                     /inference="alignment:Splign:2.1.0"
     CDS             278..1012
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein FAM168A"
                     /codon_start=1
                     /product="protein FAM168A isoform 1"
                     /protein_id="NP_001349098.1"
                     /db_xref="CCDS:CCDS90280.1"
                     /db_xref="GeneID:319604"
                     /db_xref="MGI:MGI:2442372"
                     /translation="MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTN
                     SPSYAPEFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFR
                     YTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAA
                     QPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTA
                     IGAHPVSMPTYRAQGTPAYSYVPPHW"
     exon            348..428
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
                     /inference="alignment:Splign:2.1.0"
     exon            429..455
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
                     /inference="alignment:Splign:2.1.0"
     exon            456..581
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
                     /inference="alignment:Splign:2.1.0"
     exon            582..724
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
                     /inference="alignment:Splign:2.1.0"
     exon            725..899
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
                     /inference="alignment:Splign:2.1.0"
     exon            900..1030
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..6653
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1204
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
                     /note="major polyA site"
     regulatory      6327..6332
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
                     /note="hexamer: AATAAA"
     polyA_site      6348
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
                     /note="major polyA site"
     regulatory      6362..6367
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
                     /note="hexamer: AATAAA"
     polyA_site      6388
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
     regulatory      6423..6428
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
                     /note="hexamer: AATACA"
     polyA_site      6451
                     /gene="Fam168a"
                     /gene_synonym="2610030B18Rik; B930006L02Rik; mKIAA0280"
ORIGIN      
        1 tccctccgcc tcctcctctc ttgcctgcag ccgagcgtcc ccttccccca ctgtcgggtt
       61 tctccgcggc tactgcagag gattcagatc tgagtagctg aggagaagga ggaggaggct
      121 cccgtccctg cgcgccatcc accaccctac tggacacgga cgagggaacg agagcgtcgc
      181 cgctgtagcc tccagagaag acaagggcat cgccgcttca gttgcggccg ccgcggtttt
      241 cgtctgcagc agctcgccgg atcctcagtc ttccacaatg aaccctgttt atagccccgt
      301 gcaacctggg gctccttatg gcaaccctaa gaacatggcc tacactggtt accccacagc
      361 atacccggca gctgctcctg cctacaaccc cagcctgtac ccgaccaaca gccctagtta
      421 tgctccagag tttcagttcc tgcattcagc ttatgccact ctgctgatga aacaagcctg
      481 gccacagaac tcgtcttcct gtggcactga aggcaccttc cacctcccag tggacaccgg
      541 gaccgagaac cgaacttacc aggcatcctc tgcggctttc agatataccg cagggacacc
      601 atacaaggtc ccaccgaccc agagtaatac tgctccaccc ccctactccc catcacccaa
      661 tccctatcag acggccatgt atccaatcag aagtgcctat ccccagcaga atctgtatgc
      721 ccagggagcc tactacacac aacctgtgta tgctgcccag ccccatgtca tccaccacac
      781 cacggttgtc cagcccaaca gcattccctc tgccatctac ccagctcctg ttgctgcccc
      841 caggaccaat ggtgtggcca tgggcatggt ggcaggcacc accatggcaa tgtcagcagg
      901 taccctgctg accacacccc agcacactgc aattggggca caccctgtct ccatgcccac
      961 atacagggcc caaggaaccc ctgcgtacag ctacgtgccc ccgcactggt aaagcctgca
     1021 gcccatccaa atctggagtc acattgtatg caactactcg agtcttaccg gtgctgagca
     1081 gtctcctagc agcaccacct ctattgcaag aagagacaac ggaagtgcaa gggtcacttt
     1141 atgcatcttt aatggttttg atttttattt ttggtttttg taaaagctgc tttttctaat
     1201 ctcctaggag cctcccctcg tgcctccctc ttagccacac ccttctgctc tagcccttct
     1261 tcctacctag ccaggcccag tcctctctgc ttcttccctt ccctcagcat cctgtccctg
     1321 ggaccccggt ctagtagcaa gcagagagtg aggtttattg tgatggttca tctaaaggct
     1381 agattcgttt ggagagcaga acaaatgtgg ccctccgtgt ggagtaggga cttgaagctg
     1441 tcgagaaggc cacatctctg tcagattgtc attttctgaa gcaagattag ttcaaaaaga
     1501 aagaaatatc taagaaccat cacaacagac caagaacaaa cccacctggt tatgtaggaa
     1561 tgttagcagc ttcatgtccc caggctcaga acctgggaaa gcagagagtt tggggaaggg
     1621 tggagggagg gaagacactg gggagggagg tagtgtgaag aagggcagga gggtgcttag
     1681 ctctggtttg aaaggtctcc ggccccactg ctgggcctgg accttctgat ttgcacagtg
     1741 atgttaactg acctggcact tccttcagag atgctttgac ctcagacctg ccaaacagct
     1801 gcatgtgctg ggataccagc atccagaggc ttcgcataat cccacaccca gcctgagcct
     1861 cgaggacctc tcctgaggcg cttcctcctg atgagagtag gaactggtgg catttctctc
     1921 ccttgccctt ctgcccttcc ccgtgccgga cgcacacgtc tgtctgtggg gctggcaggc
     1981 aggccaagct cttggttacc ttgtgccatg tcacggccaa agtgaaggaa ccacattcca
     2041 ggtgggagct ggcggttctg aaggtcagga tagtgaagga aaacaatagc aataatcatt
     2101 tcatactcat ggaactgaag gaaccttagc atccatcatc tcacccagtc ccctatctga
     2161 cagatgagga aactgaggcc cagagaagca gaaaggactt ctctgaacct cactgtaaat
     2221 tagcattaaa tgcagccgtc ctactactgg cattttacct acaaaaattt tgctagggat
     2281 ggattggctt gactttgtaa gaattaagtc agcagtgcca catctggtga gctctgtaat
     2341 gacctctggg cttgtttctg ctgttccccc acggactcca aaggtggggg ctaagagagg
     2401 ccacatagag caggcggcag aaatagaaat tacacttgga aaacctatga agacatctgg
     2461 aatgttcatc ttgaacctga ctccactcca ggaaaaggag taggtgggct gactggaagg
     2521 agagcctgtg cacttaggac agtagctctt tatcccaaga agagaggaag agtgggagcc
     2581 acccagagag gtgcacatga atgaggccaa gcagatacag tcacatctgg gagaagaggg
     2641 accccgacca gccaccctcc tgtgcacagc tagcaaagcc gacatcttcc ctgggtggaa
     2701 caggaatacc ttactgtgta aaattggatc actggtaata tttcagactt gaattatttt
     2761 cattttaaat tcattttaaa cttggacatc accttcctat ttcccaagtc cccctaaagg
     2821 aaaaaaaaag gaaaccactg agctggaatg acctcagaaa cagtctgact gtccccaggg
     2881 ggtcagagtt cttcagcgtc tgtggcaaag agccagaagt taaggctgct accttcctgg
     2941 tctcccagga acttcaggac caggaaaact cagctgttct ggggtgctga caaggtttca
     3001 ttttaaaaca aagttttcca gtgttaatct gatcttataa cacctctccc tgtcctctgt
     3061 ggttttgtag aggtggatga aggttgctag agatcatgtc taacatgtta aaaaatgcca
     3121 aactgataaa ggtggtggta attgtaggtt acatttgtta ggtgcttcat tagtttcaaa
     3181 gcacttcatg acctttaata tactgaccct gagagcaagc aacagggtcg gttattccac
     3241 tcacttgaca agtgatgcga tagattctaa ggagaaatga aatggcccaa agtgagctca
     3301 ctgctgggat cctggcaggc tacctagacc ccacggtctc caggtgacct ggtggcagag
     3361 gaaaacacag acccaggagt ggccttttca tgtttgttct ttctacacca gtaaataaaa
     3421 gctgtttgca cccctcactg ttcatgtggg ttagccctga cagatgaagg catggagcct
     3481 gctatttaat tcatagaggt tccaaggctc cgaaaagtac agggactttc tggtaaggaa
     3541 ccccctgctg gcgctgttct ctccaggcct gatccaaaca taggctcatg ttctgaagca
     3601 tctgtgctct gcacctcatc tgggattcaa gagcagaaaa gtcccaaggt gaaaaccaag
     3661 tattggcatg ctgtagtcta gaagaaccag acccattaac tctttttagt aagagcacaa
     3721 aagctggcct cacccttttg tttgatagag atccacaagt ctagccaagc ttagggagtc
     3781 atagtgaagg gactgagccc tagggcacag ggggttatgt gaccacagct ggcaaggtga
     3841 cacgtagctg gcaggaatac tctaggtatc atctaaacag tctggaggct cagtggtcaa
     3901 gacagaggag gccagagctg gaagggtccc ctcaccatag gatgaggggt gtgcacatga
     3961 ccatgagctg ccacactggc atcaccatac acagacacct tgtccacacc ttttcccctc
     4021 cccagtgcag tgctgaagga gaggtgcctg aaggagaggt gcctctgttc accagcctcc
     4081 cttatcacca tttgttcacc tttatccacc ctgggccagg aagtctggaa actggactac
     4141 tcacagttag tgaaagcctg agagtctctt gtcatgctta aaacaaaaca aaacaaaaaa
     4201 caaacaaaag ccctattttt cttcctataa gataaaccac gttttccttc tcgttatccc
     4261 aggaatgccc taaagtgcac ccccttccct gaatattcat cagggacaca catctatctg
     4321 tccagacctc tttttgtaaa gtactttgac tttgattgcc aaaacctcta aagataggag
     4381 gcagggtatg catcgtgatg ctatgaaggg gtcacaggct tgccaaagga cacatagctc
     4441 atgagtgaaa gagccaagat ttagactctt ctgatcctct attcttgttg ctgcctccta
     4501 ctggatctcg agtgtaagct tgcttgaaga aagaaggggt tacttgctac cccacacaga
     4561 agcgtttatg aagacttggg gagctccggt ccatcagctg agcagatttt taagaatttc
     4621 tgctttgggc caagacctat aatgggccct ggagacccag agatagatag atccagctgg
     4681 tagtacagat aggaatttgc cacaaaagac ctaactcagg acactgaagg tgacaactgc
     4741 ctagtactga agataattga ggacagtatc gtccatcttt caacaaagag tcttgcttct
     4801 ggaaagcctg cacaatctgt ccatctggct cctgtccaga tccaacaaag tacgttaacg
     4861 gggcatggta taagcctgaa ctactgaaag catgtctgga ctggagtaca aggtttattt
     4921 gagaaccaga aactaacttg tgtcccatgt atcccagtgc tttctggcca tcagggcagt
     4981 tctacgtttg agacctagca gtgtttcttt ggaaggcttg atgctctgtt ctaaatagct
     5041 ttcagaaatg agtcatggag agcatacaag tagcacaaat cccttggtca ccaagttctg
     5101 gcatctgtat tgtgcagaca tgacacatca gataaggcat tggctgaacc aggcttagtt
     5161 ccctgcatat cagatatctt gcccctgcta tgggctctgg tcttcacagc gttctggcag
     5221 aatcagtcat catcccatgt gtgactcatg ttcagtgagc tctgcttttc catcttgagt
     5281 taactacatg actgctgagt gtgtggcccc aagtatcttg tcaagctagg gagactagag
     5341 aaggagggca gcctgggttg gagtggacaa aggagagcaa agcagcggaa acatcttggc
     5401 taggtttcct gctcagacaa cacctgagcc tctagacaga cttctgtgga catgccgggc
     5461 tggcagcaag gtttgtcctt ttcctacccc tgttcgctct cctaggggga aaaaaagaaa
     5521 aaaaaaaatt gtgaaatttg gcattatgtg gttccagggc tcagctttca aaattcccag
     5581 taggccagct tcaacattcc atggccaaac tcgcctgacc tagacttggg tcccactctc
     5641 agtttctcct gtgggtattt cctaatttat aaactgttaa tgccagccag aaggccagct
     5701 aagaatatag gagttgaaac tagtggccac agagtcaaag agggacacag aagacaagca
     5761 gcacttgctt tccttaccgt ggctgctgct ttcggtagcc cttaggtagc cctgcggtgg
     5821 cagtgtgtcc ctttatcctt tccagcctga gggacaattt tctttcccaa gagaacagat
     5881 ttaaaacagc tttacagata gcagcagccc acaggaatct gctttgggtt tgaccctagc
     5941 atcctctgtc ctagacccca gctcagccat cctcctcatg catgaaagtc agactaaatg
     6001 aagaatagga ctggcccaga gacctcaggt cagccagatc aactggatct gtcttgtgaa
     6061 ccaagctcct tacaaggtga tgcaaggcta ggcctcctgc accttggagt tgtcttttat
     6121 ctttgaaggc ccagggcctg tccccttcct gtcttcaagg catctgcacc cctctttcat
     6181 agcacatgac agagaagctt gttctcatgg catggaccat ccctgtgaag agagcgttgt
     6241 gtatgatttt tgtatttttt aattcatttt aacctacagg ttggaatcta atttttaaat
     6301 tttattggaa ctcacatttt aaaacaaata aaaaacattt aaaaataata ataattataa
     6361 taataaacct ttgaccagtg tcttccaagt agtttgatca aataatttat agatgttttc
     6421 aaaatacagc ctggagtgta aagattggaa agccctgtgg ccacgcttgt gtgtatgaag
     6481 tgtaaatctg gctttgttgt tttggattcc tttgggtttt gctttgtttt gaagatcaga
     6541 tagtgatcac tctgaatggt tgaagccaag agtttgtaac tatgatattt actgtaagct
     6601 gtagaacatt caacaactat taaaagaaag tttccaaaaa aaaaaaaaaa aaa
//
