LOCUS       NM_177838               3892 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus family with sequence similarity 163, member A
            (Fam163a), mRNA.
ACCESSION   NM_177838
VERSION     NM_177838.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3892)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3892)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3892)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 3892)
  AUTHORS   Kay,J.N., Chu,M.W. and Sanes,J.R.
  TITLE     MEGF10 and MEGF11 mediate homotypic interactions required for
            mosaic spacing of retinal neurons
  JOURNAL   Nature 483 (7390), 465-469 (2012)
   PUBMED   22407321
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK039197.1, AC159964.5 and BB084026.1.
            
            On Mar 14, 2013 this sequence version replaced NM_177838.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK039197.1, BB633042.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849379
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2362              AK039197.1         2-2363
            2363-2364           AC159964.5         162762-162763       c
            2365-3882           AK039197.1         2364-3881
            3883-3892           BB084026.1         145-154
FEATURES             Location/Qualifiers
     source          1..3892
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 67.71 cM"
     gene            1..3892
                     /gene="Fam163a"
                     /gene_synonym="A230106N23Rik"
                     /note="family with sequence similarity 163, member A"
                     /db_xref="GeneID:329274"
                     /db_xref="MGI:MGI:3618859"
     exon            1..197
                     /gene="Fam163a"
                     /gene_synonym="A230106N23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            198..295
                     /gene="Fam163a"
                     /gene_synonym="A230106N23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            296..317
                     /gene="Fam163a"
                     /gene_synonym="A230106N23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            318..537
                     /gene="Fam163a"
                     /gene_synonym="A230106N23Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             445..951
                     /gene="Fam163a"
                     /gene_synonym="A230106N23Rik"
                     /note="cebelin"
                     /codon_start=1
                     /product="protein FAM163A"
                     /protein_id="NP_808506.1"
                     /db_xref="CCDS:CCDS15390.1"
                     /db_xref="GeneID:329274"
                     /db_xref="MGI:MGI:3618859"
                     /translation="MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKGTDGEDA
                     EEEEEEEEHGLSIHPRVPACNACSSHVLDGRGGLAPLTSESCSQPCGVASHCTTCSPY
                     RTPFYIRTADMVPNGGGGERLSFAPTHYKEGGTPSLKLAAPQNYPVTWPSSGHEAFTN
                     PRAISTDV"
     exon            538..3892
                     /gene="Fam163a"
                     /gene_synonym="A230106N23Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3862..3867
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam163a"
                     /gene_synonym="A230106N23Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3887
                     /gene="Fam163a"
                     /gene_synonym="A230106N23Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcgcagagtc cagggcagcg ctgagtggga gccacggcaa gagccacggc ggagagaagc
       61 ccggacccgg ggacccagga ggcaatttcc tacgcagagg gagtgaggcg gcgcggcgga
      121 gcagcagacg gatctctggg ctcggtgcgt ggatgtgccc ggcgctagag cgctgtcggg
      181 ggcgcctgaa cacctagcag ggacccatga tgcccttggc catgatgcct ccccagctgc
      241 tatctgctca tgttcagcct gcatgagtga gccaccgctg ctccagctgt ttcctgtcat
      301 cgctcccttc actgaatgaa accaatgcgg gcctgggtcc actcagctcc tgtcctcctg
      361 tctactgctg tgcagagaat gtggaccaac tactcctcac ttaccggcat acatctttgc
      421 agagtttgat ggggcgccgg gcggatgaca gcgggaacgg ttgtgatcac tggcggaatc
      481 ctagctacag tgatcctcct ctgtatcatt gctgtcctgt gctactgtag gctccagtat
      541 tactgctgca agaagggcac agatggcgag gatgctgagg aggaagagga agaggaggaa
      601 cacggccttt ccatccatcc ccgagtcccc gcctgcaatg cctgcagctc ccacgtcctg
      661 gacggcagag gcggcctggc acctctcacc agcgagtcct gcagccagcc gtgtggggtg
      721 gccagccact gtaccacttg ctccccttac cgcaccccct tttacatacg gacagctgac
      781 atggtgccca acgggggtgg aggcgagagg ctctccttcg cccctacaca ctacaaagag
      841 gggggaaccc catccctcaa gttggcagca ccacagaatt acccggtgac ctggccaagt
      901 tctgggcatg aggccttcac taatccaagg gctattagta ccgatgtata atcctttcac
      961 cccaatctgc acacacccaa cactgcggtc ccagcaggag caatggagtg ttggagggga
     1021 ctctccaatc gccctctccc ccagaaacca tttcagtttc tctggcttcc agatcagagg
     1081 tacagtaaga tgtgtacaag taaatgcttg aggaccaggg caggacctgt cgccagccct
     1141 gtggcccaga ggtagggacc tgataggtct gcaatgtcac cagtttctct ctggggattt
     1201 tctctctgac aatcaagcgc tatatgacac cttccaataa gccccaagcc ctttgctttg
     1261 atgggttgtg taaagaccag ggaaagctaa gcaaaggtta gggaggcttc cagagacctt
     1321 gggagatgag gtgggcagac ctaaaagaaa cggacacaaa gggtgaggct tagacatccc
     1381 agagcttgag aggagagagg aaagggcgtt aacggggccc ctcggggttt gcttgctaga
     1441 atgcacacat gagctagttt acactctgtt atttacttgg gttgcctgct ctgataggaa
     1501 tattgagttc tggaagcacc acatctgcta atctagtccc tcctcatgaa acacatcaaa
     1561 ctgatgctaa gcgccacaac acacgactgc ttatggggac tgtagcaaga agaggctata
     1621 taaccttgtc tccccttcaa gtcctttctt atgcccccct gctagagaaa cttttccagg
     1681 tgtcagtcat tatagttcta gaagcccagg gaacagatag atcacattga ttcgccccat
     1741 ccctccatgc cttgccacat agactcggcc ctctgagggt gtgcggatgc ccattcctgg
     1801 ggtgggggct ggcttcctct catatccatc accaccaaca gccatgtggc tttgcctcct
     1861 tcgggagctg cagagcagaa aggtccaagg gaccaacaag taagaaaaat ctgacccttt
     1921 agcaactgga cccagaggca attcaagtgg ccagtctcca tggcaaccag aaggagggaa
     1981 ctgaggcaat ggtgccacag ttaagttccc acacacctgc ataagctcct cgagaggctg
     2041 gtgcatccca tgagtgtcca tctatgatgt gacattatta acaggacatt ttatcccacg
     2101 aggggctgtg gccttctcat ctgagttttg gggggatctc ctgaaggttg gctgtgtctt
     2161 tgtaattaga tattatgctt gcctcttggt aatgagctaa tttgctgttt cagatcccaa
     2221 cacctcccac tttccatcta gcagtggcct tatggggttt tgttttttgt tttgttttgc
     2281 ttagtttagt ttagttttgg gttttgttgt tgttgttttt ggttttttgt tttttggttt
     2341 tttttttgtt gttttttttt ttttgtattt ttagttctcc agttacctcc gtgattcaag
     2401 gatcgctgtc cccacttcta aaaattaatg cctgcacatt ccagagtctc ggaatgctat
     2461 ggagggtggg ctggtttttc tcctgaaatc ttgttggctg ttggttggtt ggtctgacaa
     2521 aaagcagggt gcatcttaca tgtccaactg taaataatga acacagggtt aagaagcagg
     2581 agacactctc tgctcatgtt ctgtccactc cttagctcct gggaccagtc aggtgtcttc
     2641 actcagacat ccatttttct ccaggaacga agagcttgtc ccttagtgtt ccacaaatct
     2701 gagacgtctt agacctgctc ctcagcctcg tctcttgcct tcatccaggc cagggctggg
     2761 tggactctcc tgctgactga tcctgggtac agggacattt gttgtgggtt agaaaccaca
     2821 aaaggggtgc tgggaggaag cacggacaat tagaagacaa aatcatttga attgctgtcg
     2881 gggctaaggc agtagttcag ttgatagagc tcttgccagg tctgcacaaa acctcaagtc
     2941 tccagcactg cataaaagcc aacttggtgg gtacacctct atactgggga ggtagaggga
     3001 ggaaggtagt tgttcaaggt catccctggc tacgtagaag ttcaaggtca acctggggtt
     3061 cctgagacac acacccctct caaaaacaac aaaaacattt gttcaacccc ctactgagca
     3121 acctcaaaag gcaagtactg cctctgggag cctcagcagg agagctaacc tccccctctc
     3181 cccggtgcag agggatggct ctgcagttgt tgtgcaccca gtcccgccca tctgctcatc
     3241 ctgggccatg tgcaaccctt tgatttgctg ctgggcctgg cagctttccc cacttcctct
     3301 ctaccagccc agtgccttgc tctcctgtgg tcccacagct tcaccctaga taacaatgcc
     3361 atcgtaccca tgcctttggg taaaccaaga gaacccagcc atctgtaagc cacttttcta
     3421 ctatgggctc tgggtataaa gcactctttg cctttgtgtc tccagcaggg ccacaattca
     3481 aaatctggat cccaggtgtc agaggggacg gggaatacac actgcccttc agcccacatt
     3541 gttcaaggca caggttccac ccttggctac aggtcacctg accccctcac tcttcactgt
     3601 agcatcatga gcatcttcca tccttgggga agaggaggct cacccaactc ggctcttctg
     3661 tcccattagc tgctgagtct gtaccatgag atacaatttg tccactcttc aaactgaacc
     3721 ctaaacaggc agagaaggga ggcccgggga atagccagcc ctctccacca tccttctcca
     3781 catcactccg ctcctcctgc tgcagatttc ttgtcttgtt gtatctttga taacttggaa
     3841 cacaaaccaa gcgaatgtca aaataaagga gaaattttaa gtagaaaccc ca
//
