LOCUS       NM_172581               3328 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus family with sequence similarity 161, member B
            (Fam161b), transcript variant 1, mRNA.
ACCESSION   NM_172581
VERSION     NM_172581.4
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3328)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC120402.10 and AC159649.3.
            
            On Jan 11, 2023 this sequence version replaced NM_172581.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK036740.1, SRR9219382.41033.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-98                AC120402.10        32181-32278         c
            99-421              AC120402.10        28017-28339         c
            422-975             AC120402.10        26413-26966         c
            976-1313            AC120402.10        25199-25536         c
            1314-1441           AC120402.10        24289-24416         c
            1442-1606           AC120402.10        19095-19259         c
            1607-1706           AC120402.10        18766-18865         c
            1707-3328           AC159649.3         196530-198151       c
FEATURES             Location/Qualifiers
     source          1..3328
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 39.17 cM"
     gene            1..3328
                     /gene="Fam161b"
                     /gene_synonym="9330169D17; 9830169C18Rik"
                     /note="family with sequence similarity 161, member B"
                     /db_xref="GeneID:217705"
                     /db_xref="MGI:MGI:2443027"
     exon            1..98
                     /gene="Fam161b"
                     /gene_synonym="9330169D17; 9830169C18Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..1814
                     /gene="Fam161b"
                     /gene_synonym="9330169D17; 9830169C18Rik"
                     /codon_start=1
                     /product="protein FAM161B"
                     /protein_id="NP_766169.1"
                     /db_xref="CCDS:CCDS26043.1"
                     /db_xref="GeneID:217705"
                     /db_xref="MGI:MGI:2443027"
                     /translation="MTVGRTAGGPECAEWSREIFPPKSSSSDTEPEDEQFGEGLVLPR
                     AGKLHEFLSPEEDTDSTSDSTGSFYRTPQVPKQRGRWDVLESLFQSDPDSDLNDAEDE
                     EDLESFFQDKSRGKPQVQDPPSLRHGSMRRCSSMTSLPSDIPKARILPTSDSGPPSQH
                     RSVCSWASSITVPQPFRMTLREARKKAQWLASPASFEQERLQAQKQGEEEAECHRQFR
                     AQPVPAHVYLPLYQEIMERREARRRAGIRKRKELLLSSLKPFSFLEKKEQQKEDAPQR
                     DSAAVAQTKVSPKKATSRKIPKSILEPALGDKLQEAELLRKIRIQMRAMDTLRMASSP
                     VSTARNRAPRTAARTQEEKLSFLQTEFEFQPKVNPVVPDYEGLYKAFQKRAAERRETR
                     ETTRNKPFLLRTANLSHTPRSCDAATAGGGKKSPQPTATPLPRSRSLSGLASFSANTL
                     PVHITDATRKRESAVRMSLEKKDKSDMSIQWLEVHKKNCQAMSKSVTLRAKAMDPHKS
                     LEEVFKAKLKENRSNDRKRAKEYKKELEEMKKRIQTRPYLFEQVTKALARKEAEERYR
                     DALKQAGLEEEFVRTKSQGTEAV"
     exon            99..421
                     /gene="Fam161b"
                     /gene_synonym="9330169D17; 9830169C18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            422..975
                     /gene="Fam161b"
                     /gene_synonym="9330169D17; 9830169C18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            976..1313
                     /gene="Fam161b"
                     /gene_synonym="9330169D17; 9830169C18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1314..1441
                     /gene="Fam161b"
                     /gene_synonym="9330169D17; 9830169C18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1442..1606
                     /gene="Fam161b"
                     /gene_synonym="9330169D17; 9830169C18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1607..1706
                     /gene="Fam161b"
                     /gene_synonym="9330169D17; 9830169C18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1707..3328
                     /gene="Fam161b"
                     /gene_synonym="9330169D17; 9830169C18Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3300..3305
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam161b"
                     /gene_synonym="9330169D17; 9830169C18Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3328
                     /gene="Fam161b"
                     /gene_synonym="9330169D17; 9830169C18Rik"
                     /note="major polyA site"
ORIGIN      
        1 actgctgctt tcacctctgc ttctctctct ctctagttag gaagatgact gtggggagga
       61 ctgcgggagg tcctgagtgc gccgagtgga gccgtgagat atttcctccc aagtcgtcct
      121 cctcagacac tgagccagaa gatgagcagt ttggagaagg gctggttttg cccagagctg
      181 gcaaactcca tgagttcctc agcccggagg aggacacaga ttctacttcc gactccacgg
      241 ggagctttta tagaacccca caggttccga agcagagagg ccggtgggat gtattggagt
      301 ctctcttcca gtctgatcca gacagtgatc tgaacgacgc tgaggatgag gaagacttgg
      361 agagcttctt ccaagacaag agcaggggga agccacaggt ccaggaccct ccatctctta
      421 ggcatggctc catgaggcgc tgcagctcca tgactagcct tccctctgac attcccaagg
      481 ctcggatcct gccaacctca gactctgggc ctccctccca gcacagaagt gtttgctctt
      541 gggcatcttc catcaccgtc cctcagccat tccgcatgac actgcgtgag gcccggaaga
      601 aggcccagtg gctggcctca cctgcctctt ttgagcagga aaggctacag gcccagaagc
      661 agggcgagga agaggcggag tgccatcggc agttccgggc ccagcctgtg ccggcacacg
      721 tctacctgcc cctctatcag gagatcatgg agcgcagaga ggcaaggagg cgcgctggga
      781 ttcggaagag aaaggaactc cttctctcct ccttgaagcc cttcagcttc cttgagaaga
      841 aagaacagca aaaggaagac gctccacaga gagactcggc tgctgtggct cagaccaagg
      901 tctccccaaa gaaggccact tctaggaaga tccccaagtc cattctagaa ccagcccttg
      961 gcgacaaact ccaggaagcg gagctcctca ggaaaatccg aatccagatg agggccatgg
     1021 acactctccg gatggcttcc tcccctgtca gcaccgcccg aaacagggct ccccgaacgg
     1081 ctgcccgcac ccaggaggag aagctgagct ttctacagac tgagttcgaa ttccagccga
     1141 aggtgaaccc tgtggtccct gactacgagg gcctttacaa ggctttccag aaaagagctg
     1201 ccgagaggag ggagacccgg gagacaacca gaaataagcc cttcttgcta agaactgcca
     1261 acctgagtca cactccacga tcctgtgatg ctgctaccgc tggtggaggg aagaagtccc
     1321 ctcagccaac agctactccc ctgccaagga gtcgttctct gagtggtctc gcttcttttt
     1381 ctgccaacac tctccctgtg cacatcactg atgctaccag gaagcgggaa tctgcagtcc
     1441 gaatgtcact tgaaaagaag gacaaatcag acatgagcat tcagtggttg gaggtgcaca
     1501 aaaagaactg tcaagccatg tctaaatcag tgaccttgag ggccaaggcc atggatcccc
     1561 acaaaagcct ggaagaggtg ttcaaagcga agcttaaaga gaaccggagc aatgaccgta
     1621 aaagagcaaa ggaatataag aaagaactgg aggaaatgaa gaaaagaata caaacaaggc
     1681 cctatctctt tgaacaagtt accaaggccc tcgccaggaa agaagcagaa gagcgctata
     1741 gggacgccct gaagcaggcc ggcctggagg aggagtttgt gagaaccaag agtcaaggca
     1801 cagaggcagt gtgatgaaga gaaagccaaa gtcaaggaat ctcaccggtt aagaggtatt
     1861 ggtgttatcc ctaaggacgc gaccaggagg gaacgtagag aagttgctca cgtgagataa
     1921 cagccctgca cttacacaaa agcgcatcca caagcccctg agcaacactg tctatgtgag
     1981 gcgatggctg ctcggctgcc atccctgctc cttacagctg acaccccagc atcacctctt
     2041 tcataactga tgtatcataa ggcaaggaga gaaaagcaga gtgctgctgt tatttccagt
     2101 tttattaagt ccaagtaatt cctgttttct ctttaaaatt ctattctacc aaaaaatata
     2161 ataataatga aaatgttgga accattctta aacctcacag atcctttcca tttaaaatac
     2221 tgtttttttc agcaactatg aagctacaaa actcagcatc cgaggttgac ggctcaattt
     2281 agaagacttt acaactgcct gctggcccca ggctggaaca gcaatggcta accaatctgc
     2341 ttgttgaaat aggtcactca ccatatcaca tcagagcacc aagcaaccaa gtgtggagga
     2401 gcttgagttt agagtcatct gttagggttt gggagaacag aacagaactt cagagatcaa
     2461 agtggatccg agggtagatg taccttagcc cagagtaaaa ggctcttgct ttgcacttta
     2521 cacttagaag taggtataga aaatacaagt agagcccaca tctatcaagt aggtataaga
     2581 ggaacagagg taagaaaata ggtggcaata aggaaacaga aatccaggac agccagacta
     2641 aatacattct catcggcttc cagtaacctg caatcttagc agctaaacat aggaatactg
     2701 tgtgtgaaat aaaacatgat tctcagccca catctgcaac cttaagtaca ggccttatca
     2761 ttagcatctg acacactcgg acaagtcagt tcttattgtt tgtaggatta atttataagc
     2821 ttttttttaa aaaaggattt atttattttc tatgaataca ctgtagccat cttcagacaa
     2881 atctagaaga gggcatcata tcccataaca gatggttgtg agccaccatg tggtttctgg
     2941 gatttgaact caggacctct ggaagagcag tcagtgctct taaccactga gccatctctc
     3001 cagcccccta taggatgttt tcttcctcac cctcttgtaa cacccctctt caggttgttg
     3061 acaaacaaaa atgtttccat ttattgccaa atggtctcta gagagcaaaa atgtcccaga
     3121 ttgggaagca ctcctgtaga aagcacagac tggtaatttt agaaaaacaa ttgctaggaa
     3181 cttgtctcca cactagagga taattatgca agtcgatagc aaatgcagag cggcagttct
     3241 tttctactgt tctctaaaga cactattcga atacgtatgt cagcacagag ttcactttaa
     3301 ataaaactta actgattttg tactcata
//
