LOCUS       NM_146149               1966 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus family with sequence simliarity 151, member A
            (Fam151a), mRNA.
ACCESSION   NM_146149
VERSION     NM_146149.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1966)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1966)
  AUTHORS   Findlay,A.S., McKie,L., Keighren,M., Clementson-Mobbs,S.,
            Sanchez-Pulido,L., Wells,S., Cross,S.H. and Jackson,I.J.
  TITLE     Fam151b, the mouse homologue of C.elegans menorin gene, is
            essential for retinal function
  JOURNAL   Sci Rep 10 (1), 437 (2020)
   PUBMED   31949211
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1966)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 1966)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 1966)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   6  (bases 1 to 1966)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC024430.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC024430.1, BC026682.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1966
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 49.74 cM"
     gene            1..1966
                     /gene="Fam151a"
                     /gene_synonym="2010309H15Rik"
                     /note="family with sequence simliarity 151, member A"
                     /db_xref="GeneID:230579"
                     /db_xref="MGI:MGI:2657115"
     exon            1..174
                     /gene="Fam151a"
                     /gene_synonym="2010309H15Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             48..1874
                     /gene="Fam151a"
                     /gene_synonym="2010309H15Rik"
                     /codon_start=1
                     /product="protein FAM151A"
                     /protein_id="NP_666261.1"
                     /db_xref="CCDS:CCDS18425.1"
                     /db_xref="GeneID:230579"
                     /db_xref="MGI:MGI:2657115"
                     /translation="MSCKKWCSSSQAKWILAGSVTVTLVLAISLILGLTLHQGTQPGC
                     ENDAICGPDADMLDYLMGMGQISHRDGLLVTWYHAANSKKEMAAALNSDVMVLEADVT
                     VEGFNTANETKVPIMAHPPAIYSDNTLQEWLEAVLASSQKGIKLDFKSLKAVGPSLDL
                     LRQLTEAGRIRRPVWINADILRGPNVPISIEINATQFLTLVQEKYPKATISPGFTTLY
                     VPQLPNSTYTQAMVETMQELVGALPQKVTFPVRAVMTRAAWPHFSWLLSQSERYSLTL
                     WQGASDPVSVEDLLFIRDNSAAHQIYYDLFEPVLSQFKQLALNTTRKRTYYTGGSLIP
                     LLQQPKGDGLEVEWLVLEVNGSGRRAAITVPDREGMILLDIGLQEPEAGNPVPILHTP
                     GGPALTLESCLLRLAVHPRRWGIHVNIVEPEALRPSLATLAHLSTLGHLPWPVWVGST
                     VSHGSFVVPGHIAGRELLTAVAEVFPHVTVAPGWPEEMLDSGYQEQMVTDMLELCQGL
                     RQPVSFQLQAGPLSQSPANTVARLLASSPRATVTVYHSTAGNSHVDLWAGLWAARAVD
                     RTRVYYRISQEYWKDLQADVSSNRPSSRIGPSSVEGFPGESR"
     exon            175..321
                     /gene="Fam151a"
                     /gene_synonym="2010309H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            322..474
                     /gene="Fam151a"
                     /gene_synonym="2010309H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            475..634
                     /gene="Fam151a"
                     /gene_synonym="2010309H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            635..859
                     /gene="Fam151a"
                     /gene_synonym="2010309H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            860..999
                     /gene="Fam151a"
                     /gene_synonym="2010309H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1000..1143
                     /gene="Fam151a"
                     /gene_synonym="2010309H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..1897
                     /gene="Fam151a"
                     /gene_synonym="2010309H15Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1874..1879
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam151a"
                     /gene_synonym="2010309H15Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1897
                     /gene="Fam151a"
                     /gene_synonym="2010309H15Rik"
                     /note="major polyA site"
ORIGIN      
        1 agatgactgt gagatcctga agggagctct cttgagtgag ggtcacaatg tcctgcaaga
       61 aatggtgctc cagcagccag gccaagtgga tccttgctgg cagtgtcact gtgacactgg
      121 tgttggccat ttcattgatc ctaggcctaa ccctgcatca gggcacccaa ccaggctgtg
      181 agaacgatgc aatttgcggt cctgatgctg acatgctgga ctacctgatg ggcatgggcc
      241 agatcagcca ccgggatggc ttgctggtca cctggtacca cgcagccaac agcaagaaag
      301 agatggcagc tgccctaaac agcgatgtca tggtcttaga agccgatgtc accgtagaag
      361 ggttcaacac agccaatgag accaaggtgc ccattatggc ccaccctcca gccatctaca
      421 gtgacaacac cctgcaggag tggctagaag ctgtactggc ctcatctcag aagggcatca
      481 aactggactt caagagtctc aaggctgtag gcccctccct ggacctcctt cggcagctga
      541 ctgaggctgg caggattcgg agaccagtgt ggatcaatgc tgacatcctg aggggcccca
      601 atgtgcccat ctcaattgag atcaatgcta cccagtttct gactcttgtc caggagaaat
      661 atccaaaggc caccatttct ccaggcttta ccactcttta tgtgcctcag ttgccaaaca
      721 gcacatacac ccaagccatg gtggaaacaa tgcaggagct ggtcggagcg ctgccacaga
      781 aggtcacctt cccagtgaga gctgtcatga cacgggctgc ttggccccac ttcagctggc
      841 ttctgagcca atctgagagg tacagcctaa cactgtggca gggtgcctca gaccccgtgt
      901 cagtagaaga tctcctcttc atccgggaca acagtgccgc tcaccaaatc tactatgacc
      961 tctttgagcc tgtcttgtcg cagtttaagc agctggcctt gaacaccacc cggaagcgaa
     1021 cctactacac aggtggcagc ctgatccctc ttctccagca gcccaagggt gatggtctgg
     1081 aggtagagtg gctagttctg gaagtgaatg gcagtgggag aagagcagcc attacagttc
     1141 ctgacagaga aggcatgatc ttgctggaca ttggcctcca ggaacctgag gctgggaacc
     1201 ctgtacccat cctacacacc ccaggtggcc ctgctctgac actggagtcg tgtctgctgc
     1261 gtctggctgt tcaccccagg cgctggggca tccatgtgaa catagtggaa cccgaagctc
     1321 tccggccatc cctggccacg ttagcacacc tttctaccct tggccatctg ccctggcctg
     1381 tgtgggtggg gtccacagtc tcacatggta gttttgtggt ccctggccac atagctggca
     1441 gagagctgct cacagctgtg gctgaagtct tcccccatgt gaccgtggca ccgggctggc
     1501 ccgaagagat gctggacagt ggttatcagg agcagatggt cacagatatg ctggagctgt
     1561 gtcagggact ccggcaacct gtgtccttcc agctgcaggc tgggccactg agtcagagtc
     1621 cagccaacac tgtggccagg ctcctggcct cctcccctag agccactgtc acagtgtacc
     1681 acagcactgc tgggaacagc catgtggatt tgtgggctgg attgtgggcg gccagggccg
     1741 tggacaggac ccgagtctat tacaggatat cccaggagta ctggaaagac ttgcaggcag
     1801 atgtgagcag caaccgacca tccagtagga ttggaccatc tagtgtggaa ggcttccctg
     1861 gggagtcaag gtgaataaat gtctctgctt tgttccaaaa aaaaaaaaaa aaaaaaaaaa
     1921 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//
