LOCUS       NP_079867                138 aa            linear   ROD 02-MAY-2024
DEFINITION  protein FAM136A isoform 1 [Mus musculus].
ACCESSION   NP_079867
VERSION     NP_079867.1
DBSOURCE    REFSEQ: accession NM_025591.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 138)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 138)
  AUTHORS   Babu,V., Bahari,R., Laban,N., Kulaga,J., Abdul,Z., Zakkar,B.,
            Al-Najjar,A., Lesus,J., Al-Rifai,A.A., Sattar,H., Irukulla,S.,
            Gunniya,P., Requena,T. and Lysakowski,A.
  TITLE     RotaRod and acoustic startle reflex performance of two potential
            mouse models for Meniere's disease
  JOURNAL   Eur J Neurosci 58 (3), 2708-2723 (2023)
   PUBMED   37461313
REFERENCE   3  (residues 1 to 138)
  AUTHORS   Fancy,S.P., Baranzini,S.E., Zhao,C., Yuk,D.I., Irvine,K.A.,
            Kaing,S., Sanai,N., Franklin,R.J. and Rowitch,D.H.
  TITLE     Dysregulation of the Wnt pathway inhibits timely myelination and
            remyelination in the mammalian CNS
  JOURNAL   Genes Dev 23 (13), 1571-1585 (2009)
   PUBMED   19515974
REFERENCE   4  (residues 1 to 138)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC155947.8.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC103775.1, AK141279.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..138
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 37.69 cM"
     Protein         1..138
                     /product="protein FAM136A isoform 1"
                     /note="protein FAM136A"
                     /calculated_mol_wt=15543
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylalanine.
                     /evidence=ECO:0000250|UniProtKB:Q96C01; propagated from
                     UniProtKB/Swiss-Prot (Q9CR98.1)"
     Region          5..127
                     /region_name="DUF842"
                     /note="Eukaryotic protein of unknown function (DUF842);
                     pfam05811"
                     /db_xref="CDD:461747"
     Site            124
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0000250|UniProtKB:B0BN94; propagated from
                     UniProtKB/Swiss-Prot (Q9CR98.1)"
     Site            126
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0000250|UniProtKB:B0BN94; propagated from
                     UniProtKB/Swiss-Prot (Q9CR98.1)"
     CDS             1..138
                     /gene="Fam136a"
                     /gene_synonym="2010309E21Rik; Hyccin"
                     /coded_by="NM_025591.3:88..504"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS20309.1"
                     /db_xref="GeneID:66488"
                     /db_xref="MGI:MGI:1913738"
ORIGIN      
        1 maevqqlrvq eavdamvksv erenirkmqg lmfrcsancc edtqasmqqv hqcierchap
       61 laqaqalvts elerfqdrla rctmhcndka kdsmdagtke lqvkrqldsc vtkcvddhmh
      121 liptmtkkmk eslssigk
//
