LOCUS       NM_177819               4623 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus family with sequence similarity 135, member B
            (Fam135b), mRNA.
ACCESSION   NM_177819 NM_027401
VERSION     NM_177819.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4623)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC157602.9, AC125528.4, AC157277.2, BC119174.1 and AK005816.1.
            
            On or before Oct 9, 2008 this sequence version replaced
            NM_027401.2, NM_177819.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            transcript and genomic sequence to make the sequence consistent
            with the reference genome assembly. The genomic coordinates used
            for the transcript record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849375, SAMN00849381
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-170               AC157602.9         53290-53459         c
            171-266             AC125528.4         138282-138377       c
            267-346             AC157277.2         166251-166330       c
            347-486             AC157277.2         138096-138235       c
            487-557             AC157277.2         134373-134443       c
            558-731             AC157277.2         130865-131038       c
            732-858             AC157277.2         125136-125262       c
            859-1012            AC157277.2         95905-96058         c
            1013-1062           AC157277.2         93234-93283         c
            1063-1218           AC157277.2         84194-84349         c
            1219-1292           AC157277.2         83384-83457         c
            1293-1447           AC157277.2         76704-76858         c
            1448-3461           AC157277.2         67269-69282         c
            3462-3628           AC157277.2         64897-65063         c
            3629-4531           BC119174.1         245-1147
            4532-4623           AK005816.1         1400-1491
FEATURES             Location/Qualifiers
     source          1..4623
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 32.19 cM"
     gene            1..4623
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /note="family with sequence similarity 135, member B"
                     /db_xref="GeneID:70363"
                     /db_xref="MGI:MGI:1917613"
     exon            1..170
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            171..266
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             190..4401
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /codon_start=1
                     /product="protein FAM135B"
                     /protein_id="NP_808487.2"
                     /db_xref="CCDS:CCDS49626.1"
                     /db_xref="GeneID:70363"
                     /db_xref="MGI:MGI:1917613"
                     /translation="MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRL
                     SASIVGQSESSSLHSACVHESAVHSRVFQILYRNEEVSINDAMLFRVHLLLDGERVED
                     ALSEVEFQLKVDLHFTDSEQQLRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFH
                     LSVISVAIHAALVALQQPLISFTRPGRGSWLGKGGPDTGPEQPTISLENLVFGAGYCK
                     PTSSEGSFYVPSENCIQHAHKWHRDLCLLLLHAYQGLRLYFLVIMRDIPELPTMELEA
                     LAVEETLSQLCSELQMLNNPEKIAEQISKDLAWLASHLMALWTQFLDTVTLHSQVTTY
                     LTQEHHTLRVRRFSEAFFYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLP
                     AECLDIDGDWNTLPVIFEDRYVDCPVSGHNLSVYPNFDVPVTSPAIMNLKGKEKNLIN
                     QNSSSRKDIPLSTTEAPQLGSDEDVTRRPEVQENVSTWNPIDVCSESQVYLTIGEFQN
                     RAGIPEDECWTGPRPDAVKDSLTDTDICSRSPGPDEGQTPALTYIDVQSSNKYCPRAE
                     LVQGINVQHEHRSSRESYGIVKTVPSKVVAGTSQNNSTSLNQTAALELRTLGRGVNQD
                     GKPVLLSLKLTPAEPCDPPSTALREALDTKPSQPDHAEEPEDLSALSGVIKRSASIIS
                     DSGIESEPSSVAWSEARSRALELPSDRDVLHQVVRRHAHHRNSLEGGHTESNTSLPSG
                     IQASLSSISSLPFEEEERELALNKLTKSVSAPQISSPEESAEGADTIKNTAGFSEDLD
                     PSSKENSPPRHTSLSYGGSRVQDVRAGHSLADIALDSDRPQGPGYMDIPNDKGNHPEL
                     QEPCCLDGMAETPLHVETKGLNLKIPCTIVLENSKSRSFHRAAGETAKGKPEELSMSK
                     CVLSNNSISEVRAASHHRVPEISCSPAVEAVNLNSTGVQNSSLSVNDTMTLNRRHNAS
                     LEAKHEAGTVCPTVTHTIASQVSRNQELKTGTSISGSHLNSTEAFTLDSLKAVEVVNL
                     SVSCTATCLPFSSVPKETPARAGLSSKQNPAPITHQPLGSFGVVSTYSSKLEEEVSER
                     MFSFYQAKEKFKKELKIEGFLYSDLSVLASDIPYFPPEEEEENLEDGIHLVVCVHGLD
                     GNSADLRLVKTFIELGLPGGKLDFLMSEKNQTDTFADFDTMTDRLLDEIIQHIQLYNL
                     SISRISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGL
                     WLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHS
                     ARIEMCKTALKDRHTGPVYAEMINNLLGPLVEAKDCTLIRHNVFHALPNTANTLIGRA
                     AHIAVLDSELFLEKFFLVAGLNYFK"
     exon            267..346
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            347..486
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            487..557
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            558..731
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            732..858
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            859..1012
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1013..1062
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1218
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1292
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1293..1447
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1448..3461
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3462..3628
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3629..3720
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3721..3818
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3819..3970
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3971..4081
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4082..4195
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4196..4623
                     /gene="Fam135b"
                     /gene_synonym="1700010C24Rik; A830008O07Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcctctcgg tagagacctg agacagctcg caggtgccgc caccgactcc ttggtccgcc
       61 cacagtcgct gccggtgttg gctgctggag aaggagacca gaagagagcg ggaccagagc
      121 tggaacaggg ccctaggagg tgagagagag agccctgcag tgggagacag gtaatgaacc
      181 aaaaagatca tgtctgaagt acaaggaaca gttgagtttt ctgtggagct acataaattt
      241 tataatgtgg atctctttca gagagggtac taccagatcc gagtgacctt gaaagtgtct
      301 tcaaggatcc cccacaggct gagtgcttct atcgtcggac agtcagagag cagcagtctg
      361 cattcagcct gtgtccacga gagtgctgtg cacagtcgtg tcttccagat cttatacaga
      421 aacgaagaag tttccataaa tgacgccatg cttttccggg ttcatttgct cttagatggt
      481 gagagggtag aagatgcgct gagtgaggtc gagtttcagc tcaaggtgga cctgcacttt
      541 accgatagtg agcagcagct gagagatgtg actgggacac cgatgatcag cagccgcaca
      601 cttggtctgc acttccaccc gaggaggggt ctgcaccacc aggtccctgt catgttcgac
      661 tacttccacc tgtcagtgat ctcagtggcc atacatgctg cgctggtggc tctgcagcag
      721 cccctgatca gtttcactcg cccaggaaga ggttcctggt taggcaaagg tggcccagac
      781 acaggaccag aacagcccac catttctctg gaaaacttgg tctttggagc tggatactgc
      841 aagccaactt cctcagaggg aagcttctat gttccctcag agaactgcat acaacatgca
      901 cacaagtggc accgggatct ctgtctactg ctccttcatg cctatcaggg cctccgactc
      961 tatttcctgg tcatcatgag agacattcct gagctgccca ccatggagct ggaggctctt
     1021 gctgttgaag aaacactttc tcagctgtgc tcagagttac agatgctgaa caacccagag
     1081 aagatagcag agcagatcag caaggatctt gcctggctgg cttcacatct gatggctctg
     1141 tggacccaat tcctggacac agtaaccctg cactcccaag tcaccactta tctcacccag
     1201 gagcatcaca ctttgagggt ccgaaggttt tctgaagctt ttttttatat ggagcaccaa
     1261 aaactcgcag tcttgacctt tcaggaaaac ctgatacaga ctcacagcca gctgtccctg
     1321 gacatccgga actcagagta cctcaccagc atgcctccat tgcccgcaga gtgcctggac
     1381 attgatggtg actggaacac cctgcctgtt atctttgaag acagatatgt ggactgccct
     1441 gtctcagggc ataacttgag tgtttatcct aattttgatg tcccagtgac aagtcctgca
     1501 ataatgaatc taaaagggaa agaaaagaat cttataaatc aaaactcatc ttcaagaaag
     1561 gacattccct tatctactac agaagcaccc cagctgggct ctgatgaaga tgttactagg
     1621 cgtccagagg tgcaggagaa tgtctccaca tggaatccta tcgatgtgtg ctcagaatct
     1681 caggtgtacc tgaccattgg tgaatttcaa aacagagcag gcatacctga agatgaatgc
     1741 tggactggcc ctaggcctga tgctgtaaaa gattcactaa cagatacgga catatgtagc
     1801 agaagtccag gccctgatga agggcagacc ccagcactga cctatattga tgtgcaatct
     1861 agcaataagt actgccctag agctgaactg gtacagggca ttaatgttca gcatgaacac
     1921 aggagctcaa gggagagcta tggtattgtt aagactgtgc caagcaaagt tgtagcagga
     1981 acaagccaga ataattccac ctctttaaac caaacggctg ctcttgagtt gaggactcta
     2041 gggaggggag tcaaccagga tggaaagcct gtcctgctaa gcctgaagct cacccctgct
     2101 gagccctgtg acccaccgag cactgctctg agggaagcat tggacactaa accttcccag
     2161 cctgaccatg ctgaagagcc agaggatctt tcagcgctct ctggcgttat caagaggtca
     2221 gcctccataa tatctgattc aggcattgaa agtgaaccaa gctcagttgc ctggtctgag
     2281 gcccgtagca gagccctgga gttacccagt gatcgtgacg tcttacatca ggtggttcga
     2341 aggcatgcgc accacaggaa ctctttggag ggtggtcaca cagaaagtaa cacgagcctg
     2401 cccagtggca ttcaggcttc tctttcctcc atcagctcat tgccttttga agaggaagag
     2461 cgtgagctgg cacttaacaa gctaaccaag tctgtgtctg caccccagat cagcagccct
     2521 gaggagtctg ctgaaggtgc agacaccata aagaacacag caggtttttc tgaagatctg
     2581 gacccttcta gcaaagaaaa cagtccaccc agacacactt ctctttcgta tggtgggtct
     2641 agggtccagg atgttagggc aggacattcc cttgcagata tagctttaga ttctgacaga
     2701 ccccagggcc ctggttacat ggacatcccc aatgacaaag ggaatcaccc tgaacttcaa
     2761 gaaccctgtt gtctggatgg catggctgag accccactac atgttgaaac caaaggtctt
     2821 aacttaaaaa taccatgtac tatagtgctt gaaaattcta agtccaggtc ttttcataga
     2881 gcagcagggg aaactgcaaa aggtaaaccc gaagaattga gcatgagtaa atgcgtgctc
     2941 tccaataaca gcatctctga agtcagggct gcgtctcacc acagggtgcc tgaaatcagt
     3001 tgttcaccag ctgttgaagc tgtcaacctg aattctacag gtgtacaaaa tagttcgtta
     3061 agtgtcaatg ataccatgac attgaataga agacataatg cctctctgga ggccaaacat
     3121 gaagcaggca ccgtgtgccc cactgtgact cacactattg cctcccaagt gtcacgaaac
     3181 caagagctga agacaggaac ttccatctct gggtcccact tgaactccac agaggccttt
     3241 actctggata gcctgaaggc agtggaagtt gttaacttgt ctgtgtcttg cactgccaca
     3301 tgtctccctt tctcatctgt acccaaggag acacctgcca gggctggact ctcttccaaa
     3361 caaaacccag ctcctattac tcatcagcct ttgggttcct ttggcgttgt ttctacctac
     3421 tccagcaagc tggaagaaga agtcagtgaa aggatgttca gtttttatca ggccaaagaa
     3481 aagtttaaaa aagaactgaa gattgaagga tttctgtaca gtgacttatc tgtactagct
     3541 tctgacatac catatttccc accagaggaa gaggaggaaa acttggaaga tgggattcac
     3601 ctggtggtct gtgtccatgg cctggatggc aacagtgcag acctccggct ggtgaagaca
     3661 ttcatagaac tgggactccc tgggggaaaa ctggacttct taatgtctga aaagaatcag
     3721 acggatacat ttgcagattt tgataccatg acagatcgat tgttggatga gattattcaa
     3781 cacatccagt tgtacaacct ctccatatcc cgaattagct tcatcggcca ttctcttggc
     3841 aacattatca tcagatccgt ccttacaaga ccccggttcc ggtattacct caacaaactc
     3901 cacacattct tgtcattgtc tggacctcac ctggggactc tgtacaacaa tagcaccctg
     3961 gttagtactg gtttgtggct catgcagaaa ctgaagaaat ctggctccct tttgcagctg
     4021 accttcaggg ataatgctga tctgcgcaaa tgtttccttt accaacttag ccaaaaaaca
     4081 gggctgcagt attttaaaaa cgtcgttctg gttgcttctc cccaagaccg ctatgtgcca
     4141 tttcattcag ccaggattga aatgtgtaaa accgccctca aggacagaca cacagggcca
     4201 gtgtatgcag aaatgatcaa caacctcttg ggccctctgg tagaagccaa ggactgcact
     4261 ttgatcagac ataatgtgtt ccatgctcta cccaacactg ccaacaccct gattggacgt
     4321 gcagctcata tagccgtgct ggactcggaa ctcttccttg agaagttttt cttggtggca
     4381 ggactcaact atttcaagta gtagcttcca gggagcagcc tgggtgactg tccagagctg
     4441 ctcaagatca tttgagttct tagctaggtc atgcttttcc acatctctgt attccagagt
     4501 ggagtagaag gagagtggag ggtgtggagg gataaagctg gggtgggact ggacactaga
     4561 gatgcttgta tttgagacat tggggaagtt gaacaaacag tgcaaaagat aacgatgttt
     4621 tct
//
