LOCUS       NM_173425               2862 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus family with sequence similarity 124, member B
            (Fam124b), mRNA.
ACCESSION   NM_173425
VERSION     NM_173425.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2862)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2862)
  AUTHORS   Batsukh,T., Schulz,Y., Wolf,S., Rabe,T.I., Oellerich,T., Urlaub,H.,
            Schaefer,I.M. and Pauli,S.
  TITLE     Identification and characterization of FAM124B as a novel component
            of a CHD7 and CHD8 containing complex
  JOURNAL   PLoS One 7 (12), e52640 (2012)
   PUBMED   23285124
  REMARK    GeneRIF: Fam124B is a novel protein possibly involved in the
            pathogenesis of CHARGE syndrome and neurodevelopmental disorders.
REFERENCE   3  (bases 1 to 2862)
  AUTHORS   Kas,M.J., de Mooij-van Malsen,J.G., de Krom,M., van Gassen,K.L.,
            van Lith,H.A., Olivier,B., Oppelaar,H., Hendriks,J., de Wit,M.,
            Groot Koerkamp,M.J., Holstege,F.C., van Oost,B.A. and de Graan,P.N.
  TITLE     High-resolution genetic mapping of mammalian motor activity levels
            in mice
  JOURNAL   Genes Brain Behav 8 (1), 13-22 (2009)
   PUBMED   18721260
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK043867.1 and AV276683.1.
            
            On Dec 8, 2009 this sequence version replaced NM_173425.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK043867.1, BC150872.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2468              AK043867.1         2-2469
            2469-2855           AK043867.1         2471-2857
            2856-2862           AV276683.1         194-200
FEATURES             Location/Qualifiers
     source          1..2862
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 41.19 cM"
     gene            1..2862
                     /gene="Fam124b"
                     /gene_synonym="A830043J08Rik"
                     /note="family with sequence similarity 124, member B"
                     /db_xref="GeneID:241128"
                     /db_xref="MGI:MGI:3026880"
     exon            1..1012
                     /gene="Fam124b"
                     /gene_synonym="A830043J08Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             281..1651
                     /gene="Fam124b"
                     /gene_synonym="A830043J08Rik"
                     /codon_start=1
                     /product="protein FAM124B"
                     /protein_id="NP_775601.1"
                     /db_xref="CCDS:CCDS15093.1"
                     /db_xref="GeneID:241128"
                     /db_xref="MGI:MGI:3026880"
                     /translation="MDEIQEPLALTVHLLADTGNGLLLQQALDQLLECICPEVRLFLV
                     SERARPVNYHEKYHPRRARFPGMSVLLFLQESLGQERLFRVLDFLRRSPWQGFPTQHA
                     QGRSCSYLPANQEFYSLHNQMPVWGMRPVNCGTDILRVTLYCSFDNYEDAIRLYEMLL
                     QRDATVQKSDFCFFVLYATEGFSLQLSLKQLPLGMSVDPKESSVLQFRVQEIGQLVPL
                     LPNPCVPISSARWQTQDYDGNKILLQVHPKPGVGIKNGEHPFLNGCLRGDTHPQDSSL
                     NSVSTQRTLEPRSRRRSRSRRFKVHSLELPQPSGSWENSTDPLWRRLGWSTLADSSAS
                     GMQQRRLSIPIEPKMGRNVLREDGFEKLEAETNVDTGFTIINSEPRRSFPSRFPRDFQ
                     SSQPPRCLSGSSLEVTVSPNQGVFKDRLHPLSLPSQRDFGAKKVISKCSHHLQAQGEE
                     KEEFFI"
     exon            1013..2862
                     /gene="Fam124b"
                     /gene_synonym="A830043J08Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1658
                     /gene="Fam124b"
                     /gene_synonym="A830043J08Rik"
                     /note="major polyA site"
     regulatory      2837..2842
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam124b"
                     /gene_synonym="A830043J08Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2860
                     /gene="Fam124b"
                     /gene_synonym="A830043J08Rik"
ORIGIN      
        1 ggggaatgcc cgagaaagcc aagcaaatag ttacatctgc tcagaccgga tgacatagag
       61 cgactctgtt gtgtgtagcc gactccacac ttgagtgaca ttccccgctg gagcactgga
      121 ggaagccagg agcatgtgtg atctggtgaa gaacttggtt cagaagttgc taaagatttt
      181 atagaggctg agggctctgc gtgaggcctt ggttcttcct aaaaggctga gctgtgggcc
      241 ctgtcgggtg gccttcatca taatcttcac atagcctgcc atggatgaga tacaggaacc
      301 tctagccttg actgtgcatc ttcttgccga cactgggaac ggtttgcttc tgcagcaggc
      361 tctggaccaa ctactagaat gtatctgccc agaggtgcgt ctcttcctgg tgtctgaacg
      421 tgccaggcca gtgaactacc atgaaaagta ccacccgcgg agggcccgct tcccaggaat
      481 gtctgttttg ctcttccttc aggaaagcct gggacaagaa cggttgtttc gagtcttgga
      541 cttcctacgg cgttcaccct ggcagggttt ccctacccag catgcacagg ggaggtcttg
      601 ttcttatctc cctgccaatc aggaattcta cagtctgcac aaccagatgc cagtgtgggg
      661 catgaggcca gtgaattgtg gcactgatat cctcagggtg actctgtact gcagttttga
      721 taactatgaa gatgccatca gactctatga gatgcttcta cagagagacg ccactgtgca
      781 aaagagcgac ttctgtttct ttgtcctcta tgccaccgag ggcttcagcc tgcagctctc
      841 tctgaagcag ctgcccctgg gaatgtcagt agaccccaag gagtcttctg tgctgcagtt
      901 cagggttcaa gagattgggc agctggtgcc tcttctaccc aatccgtgtg ttcccatcag
      961 cagcgcgagg tggcagactc aggactatga tggcaataag attctgctgc aggtccatcc
     1021 gaagccagga gttggcatta aaaatggtga gcatcccttc ttgaacggct gcttgagagg
     1081 tgacacacat ccacaggact ccagtctgaa ctccgtctcc acacagagaa ccttggagcc
     1141 aaggagccgg aggaggagca ggagtcggag gttcaaagta cattcgctgg agcttccaca
     1201 acccagtggc tcatgggaaa actctactga ccctttgtgg agaaggcttg gctggtccac
     1261 cctggccgac agctccgcgt caggcatgca gcagcgccga ctgtctatcc ccatagaacc
     1321 caagatggga aggaacgttc ttagagaaga tggctttgag aagctcgagg cggagacaaa
     1381 tgttgacact ggcttcacca tcatcaattc cgaacccagg cgatcttttc cgagcagatt
     1441 tcccagggat tttcagagca gccaaccacc acgctgcttg tcaggctctt ccttagaggt
     1501 aactgtttcc ccaaaccaag gagtctttaa ggatagactc caccctctgt cacttcctag
     1561 tcaaagggac tttggtgcaa agaaggtcat ctcaaaatgt tcccatcatc tgcaggccca
     1621 gggtgaagag aaagaagaat tctttatata gcataaaaca attgtggttt tttttttcct
     1681 aagacacgag aatgttatag aaaccaagcg ttgtattagt tgcctttgta gttgaaatga
     1741 gaaatatcct acaaaagcaa gcaaaggttt aagagtcagc cccattcatg gctgggaagt
     1801 cacagaagca agagtgtgac tggttacgtt tcctctacag tcaggtagca gagggggatg
     1861 gatgctggcg atctgcctgc ctttttaaaa gctcaatctg ggactccagc tcatgggaag
     1921 atattaccca tttttagggt tggtcttcct tcctcagtta aatctttctg gaaacaccct
     1981 tctagataca cccagagatg ggtttccatg gtgtgtctga atccagttga cagtgaagat
     2041 cggatctacg aacatttagt ttcttgctcc tttgagagag atctaggctc tcgatgccca
     2101 gtattagaag tccacgggga tctgacagtg tgctggccag ttggaaggga gagaaagaaa
     2161 acccagggtc tgagcttctc agagacacag ctcagatgca tgtgttggct cagcacctag
     2221 cagggccttg gcactgtgtg gaaatgaatc agatgtgcta tgcaaatctg attagtgtgt
     2281 gtaatatggt tttaattttt ccttgaggtt gcatagctta tccccttgga cagtaggaac
     2341 tatttattct ttagtgcgtt ttaatttttg tgtggcctcc tttggtaagt aggccctgtt
     2401 tacgatacac cctcttgtgg ttttgccttt aaagttcttt gcatatgaaa cgagtgaaga
     2461 atgcaaagtg ttttaaaatt ataaatacca ccccctcccc tgtttaatta gtaacaatac
     2521 tcgaagccag aaagctaggt tcaaaatgag tgctagactc agagatattt ctactctttt
     2581 gtctctcatt tgttcatgtc ctacttgaaa gagatcatca ggtcttgtta aaacaaaaac
     2641 aaacaaacaa acaaacaaac acaaaaaaac aaacaaaaca aaaacaaaca aacaaacaaa
     2701 accaaggaag acagggatga ttagaaaatt ctgtatctcc actgagcatg ccgaaaggtt
     2761 gtgttggctg agttgctaga ccaggacttg agttctagct gtattttggg ggctcctggg
     2821 gcttgtatgt tcacgtaata aacatttttt tttgcatgca gt
//
