LOCUS       NM_001037725            5534 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus family with sequence similarity 117, member B
            (Fam117b), mRNA.
ACCESSION   NM_001037725 NM_001003946
VERSION     NM_001037725.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5534)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5534)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125377.5, BC080299.1 and BY455778.1.
            
            On Oct 10, 2012 this sequence version replaced NM_001037725.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK154812.1, BC080299.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-605               AC125377.5         87608-88212
            606-5533            BC080299.1         1-4928
            5534-5534           BY455778.1         438-438
FEATURES             Location/Qualifiers
     source          1..5534
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 30.44 cM"
     gene            1..5534
                     /gene="Fam117b"
                     /gene_synonym="2810425F24Rik; 6330416D14Rik; Als2cr13"
                     /note="family with sequence similarity 117, member B"
                     /db_xref="GeneID:72750"
                     /db_xref="MGI:MGI:1920000"
     exon            1..747
                     /gene="Fam117b"
                     /gene_synonym="2810425F24Rik; 6330416D14Rik; Als2cr13"
                     /inference="alignment:Splign:2.1.0"
     CDS             159..1913
                     /gene="Fam117b"
                     /gene_synonym="2810425F24Rik; 6330416D14Rik; Als2cr13"
                     /note="amyotrophic lateral sclerosis 2 chromosomal region
                     candidate gene 13 protein homolog"
                     /codon_start=1
                     /product="protein FAM117B"
                     /protein_id="NP_001032814.1"
                     /db_xref="CCDS:CCDS14986.1"
                     /db_xref="GeneID:72750"
                     /db_xref="MGI:MGI:1920000"
                     /translation="MSQRVRRNGSPTPAGALAGGAVGPPGGPGSRLQPMRATVPFQLK
                     QQQQHGSPTRGGGGGGNNGGNGGASGPSGGGGSGGPRTASRSTSPTRGGGGSAAARTS
                     PTVATQTGASVTSTRGTSPTRGTAPGARSSPPRPQPPPPLLGTVSSPSSSPTHLWPSE
                     VIAAPPSARVRHRRRSPEQGRPSAEKRSPSAPVCKAGDKTHPPSSSSSSIIRRTSSLD
                     TLAAPYLAGHWPRDIRGQAAPCMRDKATQTESAWAEEYEKKKGSHKRSSSWGSTEQLK
                     EIAKLRQQLQRSKHSSRHHRDKERQSPFHGNHAAINQSQAPAPKSTLVPAGPITKSSG
                     SRFRNSVEGLNQEIEIIIKETGEKEEQLIPQDIPDGHRAPPPLAQRSSSTRSIDTQTP
                     GGADKGSNNSSRSQSVSPTSFLTISNEGSEESPCSADDLLADPRDKENGNNSPLPKYA
                     TSPKPNNSYMFKREPPEGCERVKVFEECSPKQLHEIPAFYCPDKNKVNFIPKSGSAFC
                     LVSILKPLLPTPDLTLKGSGHSLTVTTGMTTTLLQPISMASLSTNTEQERVSRGTSTV
                     LPSASLHAPPEPIEEAEG"
     exon            748..899
                     /gene="Fam117b"
                     /gene_synonym="2810425F24Rik; 6330416D14Rik; Als2cr13"
                     /inference="alignment:Splign:2.1.0"
     exon            900..989
                     /gene="Fam117b"
                     /gene_synonym="2810425F24Rik; 6330416D14Rik; Als2cr13"
                     /inference="alignment:Splign:2.1.0"
     exon            990..1103
                     /gene="Fam117b"
                     /gene_synonym="2810425F24Rik; 6330416D14Rik; Als2cr13"
                     /inference="alignment:Splign:2.1.0"
     exon            1104..1247
                     /gene="Fam117b"
                     /gene_synonym="2810425F24Rik; 6330416D14Rik; Als2cr13"
                     /inference="alignment:Splign:2.1.0"
     exon            1248..1473
                     /gene="Fam117b"
                     /gene_synonym="2810425F24Rik; 6330416D14Rik; Als2cr13"
                     /inference="alignment:Splign:2.1.0"
     exon            1474..1594
                     /gene="Fam117b"
                     /gene_synonym="2810425F24Rik; 6330416D14Rik; Als2cr13"
                     /inference="alignment:Splign:2.1.0"
     exon            1595..5534
                     /gene="Fam117b"
                     /gene_synonym="2810425F24Rik; 6330416D14Rik; Als2cr13"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5513..5518
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam117b"
                     /gene_synonym="2810425F24Rik; 6330416D14Rik; Als2cr13"
                     /note="hexamer: AATAAA"
     polyA_site      5533
                     /gene="Fam117b"
                     /gene_synonym="2810425F24Rik; 6330416D14Rik; Als2cr13"
                     /note="major polyA site"
ORIGIN      
        1 gcggctgcat cacctcgtcg gtgcccgtcg ctgcccgcgc gccccctggt cctgaagtca
       61 ggctacgtca cccgctggct caggccttcc ctcgggcccc gagcagccgg tccccgccgc
      121 ccagcacccc cggccgccgt ctctggggcg gggggaccat gtcccagcgg gtgaggcgca
      181 atgggtctcc cacgcccgcc ggcgccctcg cgggtggcgc ggtcggcccg cccgggggcc
      241 ctgggagccg cctgcagccc atgagggcga cggtgccgtt ccagctgaag cagcagcagc
      301 aacatggcag ccccacgcgg ggcggcggcg gcggcggcaa caacggaggc aacggaggcg
      361 cctcaggccc ctcgggcggc ggcggcagtg gcggcccgcg caccgcctca cgcagcacca
      421 gccccacgcg cggcggcggc ggcagcgcgg cggcgcgtac cagccccacg gtggccacgc
      481 agacgggagc gtccgtgacg tccacgcgcg gtaccagccc cacgcgcggc acggcgcctg
      541 gggcccgaag cagtcctccg cgcccgcagc cgccaccgcc cctgctgggc accgtgtcgt
      601 cgcccagttc gtcgcccacc cacctgtggc cgagcgaggt gattgcggcc ccaccctccg
      661 cccgcgtccg ccaccggagg aggtccccag agcagggccg accctcggcg gagaagagga
      721 gccccagcgc cccggtgtgc aaagcaggtg acaaaacaca cccgccttcc tcaagctcct
      781 ccagcattat ccgacgcaca tcttccctgg ataccctcgc agctccatac cttgctgggc
      841 actggccccg agacattcgt gggcaagccg caccctgcat gagggacaag gccacacaga
      901 ccgagagtgc atgggctgaa gaatatgaaa agaagaaagg gtctcataag cgctcatcat
      961 cctggggcag cacagaacag cttaaagaga ttgcaaaatt acgccagcaa ctgcagagaa
     1021 gcaaacacag cagtcgtcac caccgagata aagaaaggca gtctccattc catggcaacc
     1081 atgcagctat taaccagagc caggctcctg ctccaaagag cacgctcgtt cccgctggcc
     1141 ccatcaccaa gtcgtctggt tctcggttcc ggaacagtgt ggaagggctg aatcaggaga
     1201 ttgagatcat aattaaagag acgggggaga aggaagaaca gctgattcca caagatattc
     1261 cagatggtca tcgtgcgcct ccgcccctcg cacagagaag cagcagcaca cgaagcattg
     1321 acacacagac ccctgggggt gcagacaagg gaagcaacaa cagcagccgc tctcagtctg
     1381 tgtccccaac atccttcctc accatctcta atgaaggcag tgaggagagc ccctgttcag
     1441 ctgatgatct gcttgcggat cccagagata aagagaatgg aaacaattct cctttgccaa
     1501 aatatgcaac ctcaccaaaa cctaataaca gttacatgtt taaaagggaa cctccagagg
     1561 gctgtgaaag ggtcaaagtc tttgaggaat gctcgccaaa acaacttcat gagattccag
     1621 ccttttactg tcctgacaaa aacaaggtga atttcattcc taaaagtggc tctgctttct
     1681 gcctcgtgag tatcctcaaa ccacttctcc ctacaccaga tcttactctc aagggctctg
     1741 gtcacagcct gaccgtcacc actggcatga ccaccacttt gctccagccc atctctatgg
     1801 cctccctgtc tacaaacaca gagcaagagc gggtatctcg aggaaccagt acagtcctgc
     1861 catccgcctc cctccatgca ccaccagaac ccattgagga agctgaagga tagggctcag
     1921 ctcaagcaat gggtgctggg agctaagaac cctgcagatc acgtgactgt ggtatcatgt
     1981 ggtatcctgt cctcccggtt ggctgtgaag tgctttggct ttccagtgag gtgtgacagc
     2041 aaggctcctg gaagaactag tggtcctctg agtgttctgc cctgcgcatg aaggccacag
     2101 acgtgcttca cctgcttggc cttgaagcac tagctgaaac ctgaaaggtc tcttctttac
     2161 ttttggagga acaaaaatca cattttcatt tgtttcaaat tagacttgtt taaaaacaaa
     2221 atacaaaacc ggatccctgc aaacatgatt tctgaaggga gatgtgatcg atgctgcaag
     2281 aaaatcatct tttatatgaa aacgactatt ttataatacc aatgtcacat tttctgaaag
     2341 taacaaacaa gatgttccaa tgatcctttg gtggcctctg tttcttgttt cctttttcta
     2401 gatattgctt ttctcggctg ttttcagctt tgggaccaaa gggattgttg acatttcccc
     2461 agcaatgtca atctcatgac tgttcttctc ccaagtaaga attgataggt aatgcattga
     2521 accaagtata tataaaaaga taaaaagcaa tatttgtaca ttatgtgatt tatgtttttt
     2581 tgatgtcaac agtttgtgat ttgagtgaag tatttgtaaa ctgctgtttt ctgcactatt
     2641 cctgttcaca cttcatcgtg tggtcagtca gtgtgaagac aggttgcttt aacagtcagt
     2701 gagccaaaag aaactctcaa gtgtggattg ttagctagga gtatggagct ctctggtctt
     2761 ctgtgagctg tgtgtcccgt gattgccctt cctcgccgct gtcagtctga ctttgatcat
     2821 cactgtatca tatagcccca agagaccctg aaaaggctgt gcatggatcc cccctctgct
     2881 tccgtggtgg tgttgtcttg tggatttggt cagggttagt agtttgccag gagtgtgatc
     2941 ctttgagtag caatcgggag ctgcagaatc ttgagaactg actttttctt catgtgttgg
     3001 cgctgtgatt tgctacttac agattttgct agtttcttct ccaacattcc acacactggg
     3061 ggaaagagaa gaggattaga gcttagaaaa caggtacctt tggaacgtct atacagtttt
     3121 ggattcgagc tcatctgata accattgcca gtatcacatg acagtattta atttctaggt
     3181 gtgtgataat aaaattaagg agctgctctt tagaaatgaa ttccatcagt gttggtaaac
     3241 attgttttaa tatattctaa cttatgctgc tgtgtacaac aggtagatgg caaaccctgc
     3301 atgagagggc cacaattttg aaggcgaatt ccatccactg gtccagtcat tccatcatga
     3361 gaaaccaaga ggtagcagta catcttggca agctgtttgt caccttagaa tgcctagaca
     3421 gtttaaaatg ggctctgctt aattttaagg aaggatattt aggttaattg gataaattca
     3481 gacatctaag taaaatccat cagtttttgg ttggaaaaac tgatacattt tggtactttt
     3541 ttttacccaa atcttaactt cctgggaact agtaaagcat agctccttag tcagtaaaag
     3601 cctcgggttt tggagtgtag gctttttggt tggtggttgg gttttgtttc tcagtttagg
     3661 gtttttttgt accttgattt ttcgccttgt caggcctttt gactttacca ttttaccaat
     3721 atcagaagta cagaagaaag gcagctggca gtctgttgag ttgatctgaa gggagaagga
     3781 gacatttaaa agcaagggtt cttgttttgt ttgtttttga gatggctttt attatgtaga
     3841 ccaggctggc ctggcactca gatgcccctc ccaagtgctg ggattaaggg catgtgccac
     3901 cacaccatgc ttgtcttctt tttaattctg tgggttttcc ccacttgaat gctgttaatt
     3961 gatgttcttt ttcctttatc ttataccatc tcatctctcg atttacaaat agagtttact
     4021 ctgtaataga tttttccctt ttctgttata cttgtttggc agattgacac ctctgccttt
     4081 acatctatcc ttgaagtaac agagagggac aggtttcagg tcagcatctg ctcctagaag
     4141 tagaacttta gtttgaggtt tggttggaag aagattgtga atttgcaaat aaatgaatta
     4201 taaggtgacc aaacattcct gagatctaaa gaaaaacaaa aaaggtctat gtccaaaaag
     4261 aaaactgcct gggccaaagg gctaattttt aagcatatga gctttattgc agtcttaaca
     4321 tatattaacc gtagatccac ctagctgttt tatttaactc ttaattccca ggggcttggt
     4381 tttaaaagtg ggtctactct tagtagagtg ggcatgatta cattgacaag ccacactcca
     4441 taattaggtt attctgtaga aactgtacag cggtagagta gtttcaatgc aaatacagtt
     4501 tttttccagt gctggggatc aaacccaggg cctcatgcat gctgagcaag tgctgtgtcg
     4561 ctggcttatt tccccagctc ctaatttaaa actttaatta aaaaaatttt gttccattgc
     4621 agtaaaagtg ggtggcatgt attttttggc taagggtgct gttccctggt tcctggccca
     4681 tcttagttat acttgaccct caagcagttt cctccctgca gtgattattg cttctgacac
     4741 ggtaagtctg ttacttatca ctggtttatg ggcagttgtg tttaaaaaac tagtagtttt
     4801 gctttctttg gttaaatatg gtatgaatgt caattttttt tcctatacca gatccttcat
     4861 tttgtttaca gtgtttctta cttagaccta ggaccataac caaatctgcc tctctataga
     4921 tactgttgct aattggagtg tatctggcaa cagagaaagg ctgcttttta tttttatttt
     4981 ttaatgtttt gattaaagaa acagttagct tttcctagga gaaggtctaa acacagtggc
     5041 cccatggaga gctttctctg tctgggattg aactgagatc ctgaggtttt cttttaggaa
     5101 actaaagtaa acttgccatt actaaatttg taaagttgag attcactcct taatgctggt
     5161 gtggggggtg tcaaactgga ccaatggaaa tgctggattt gctaaataaa gccaagatgc
     5221 atagccctgc actttaaggt ttctggttgc tctgccttca ttagtgaccc tgcagagtgg
     5281 ctctgaacag tactttgttt atacagtcct gttggagata tataatttat gttttttaaa
     5341 cagtgcatct ttgtctctgt tgatgtaaat tttttaatgc aattttttaa agttacaaca
     5401 aaattctccc ccaaaaacag catttccagt gatgataagt attgttgtgg actgtgtccc
     5461 tgaacctgag cacttactgc tttgtcacag ggaatagaac ttcctatgtt caaataaagt
     5521 ctgttgttct tgag
//
