LOCUS       NP_001032814             584 aa            linear   ROD 30-APR-2024
DEFINITION  protein FAM117B [Mus musculus].
ACCESSION   NP_001032814 NP_001003946
VERSION     NP_001032814.1
DBSOURCE    REFSEQ: accession NM_001037725.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 584)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 584)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125377.5, BC080299.1 and BY455778.1.
            
            On Aug 8, 2008 this sequence version replaced NP_001003946.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK154812.1, BC080299.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..584
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 30.44 cM"
     Protein         1..584
                     /product="protein FAM117B"
                     /note="amyotrophic lateral sclerosis 2 chromosomal region
                     candidate gene 13 protein homolog"
                     /calculated_mol_wt=61214
     Region          1..214
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q3U3E2.1)"
     Site            10
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q3U3E2.1)"
     Site            102
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q3U3E2.1)"
     Site            206
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q6P1L5; propagated from
                     UniProtKB/Swiss-Prot (Q3U3E2.1)"
     Site            215
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q6P1L5; propagated from
                     UniProtKB/Swiss-Prot (Q3U3E2.1)"
     Site            216
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q6P1L5; propagated from
                     UniProtKB/Swiss-Prot (Q3U3E2.1)"
     Region          217..524
                     /region_name="FAM117"
                     /note="Protein Family FAM117; pfam15388"
                     /db_xref="CDD:464695"
     Region          227..461
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q3U3E2.1)"
     Site            268
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q6P1L5; propagated from
                     UniProtKB/Swiss-Prot (Q3U3E2.1)"
     Site            340
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q3U3E2.1)"
     Site            386
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q6P1L5; propagated from
                     UniProtKB/Swiss-Prot (Q3U3E2.1)"
     Site            444
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:19144319,
                     ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q3U3E2.1)"
     Site            452
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q6P1L5; propagated from
                     UniProtKB/Swiss-Prot (Q3U3E2.1)"
     Region          551..584
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q3U3E2.1)"
     CDS             1..584
                     /gene="Fam117b"
                     /gene_synonym="2810425F24Rik; 6330416D14Rik; Als2cr13"
                     /coded_by="NM_001037725.3:159..1913"
                     /db_xref="CCDS:CCDS14986.1"
                     /db_xref="GeneID:72750"
                     /db_xref="MGI:MGI:1920000"
ORIGIN      
        1 msqrvrrngs ptpagalagg avgppggpgs rlqpmratvp fqlkqqqqhg sptrgggggg
       61 nnggnggasg psggggsggp rtasrstspt rggggsaaar tsptvatqtg asvtstrgts
      121 ptrgtapgar sspprpqppp pllgtvssps sspthlwpse viaappsarv rhrrrspeqg
      181 rpsaekrsps apvckagdkt hppssssssi irrtssldtl aapylaghwp rdirgqaapc
      241 mrdkatqtes awaeeyekkk gshkrssswg steqlkeiak lrqqlqrskh ssrhhrdker
      301 qspfhgnhaa inqsqapapk stlvpagpit kssgsrfrns veglnqeiei iiketgekee
      361 qlipqdipdg hrappplaqr ssstrsidtq tpggadkgsn nssrsqsvsp tsfltisneg
      421 seespcsadd lladprdken gnnsplpkya tspkpnnsym fkreppegce rvkvfeecsp
      481 kqlheipafy cpdknkvnfi pksgsafclv silkpllptp dltlkgsghs ltvttgmttt
      541 llqpismasl stnteqervs rgtstvlpsa slhappepie eaeg
//
