LOCUS       NM_172543               2334 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus family with sequence similarity 117, member A
            (Fam117a), mRNA.
ACCESSION   NM_172543
VERSION     NM_172543.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2334)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2334)
  AUTHORS   Chambers,D., Wilson,L.J., Alfonsi,F., Hunter,E., Saxena,U.,
            Blanc,E. and Lumsden,A.
  TITLE     Rhombomere-specific analysis reveals the repertoire of genetic cues
            expressed across the developing hindbrain
  JOURNAL   Neural Dev 4, 6 (2009)
   PUBMED   19208226
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2334)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK165378.1, AK143632.1 and BC055690.1.
            
            On Oct 31, 2009 this sequence version replaced NM_172543.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC055690.1, AK143632.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-983               AK165378.1         2-984
            984-2315            AK143632.1         992-2323
            2316-2334           BC055690.1         2288-2306
FEATURES             Location/Qualifiers
     source          1..2334
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 59.01 cM"
     gene            1..2334
                     /gene="Fam117a"
                     /gene_synonym="5730593F17Rik"
                     /note="family with sequence similarity 117, member A"
                     /db_xref="GeneID:215512"
                     /db_xref="MGI:MGI:2144564"
     exon            1..244
                     /gene="Fam117a"
                     /gene_synonym="5730593F17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..1404
                     /gene="Fam117a"
                     /gene_synonym="5730593F17Rik"
                     /codon_start=1
                     /product="protein FAM117A"
                     /protein_id="NP_766131.2"
                     /db_xref="CCDS:CCDS25276.1"
                     /db_xref="GeneID:215512"
                     /db_xref="MGI:MGI:2144564"
                     /translation="MSGAAAGGRGGGSWGPGRGGAGGLRRGCSPPAPAGSPRVGLQPL
                     RATVPFQLQQPHQRRDGGGRAASVPCSVAPEKSVCRPQPPQVRRTFSLDTILSSYLLG
                     QWPRDADGAFTCCTNDKATQTPLSWQEPEGERASFCMHKRSASWGSTDHRKEITKLKQ
                     QLQRTKLSRSGKEKERSCPVQGDHAALGAGRASLPSHPPGPPVLRLSPCLHRSLEGLN
                     QELEEVFVKEQGEEELLRILEVPDGHRAPAPPQNSSCDHSLLLEPGNLTSSPSVPLAS
                     PQPPSQASREEHQGATEELASIHGNKASSPGNPAFLEDGSPSPVLAFAASPRPNHSYV
                     FKREPPEGCERVRVFEEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVSLIKPLFPS
                     MGFIFRNCPSSPGSPLPTASPRAPRKGPEASKASSLPSEPWQRSPPSEESVLFQSSLV
                     V"
     exon            245..414
                     /gene="Fam117a"
                     /gene_synonym="5730593F17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            415..510
                     /gene="Fam117a"
                     /gene_synonym="5730593F17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            511..621
                     /gene="Fam117a"
                     /gene_synonym="5730593F17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            622..756
                     /gene="Fam117a"
                     /gene_synonym="5730593F17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            757..955
                     /gene="Fam117a"
                     /gene_synonym="5730593F17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1106
                     /gene="Fam117a"
                     /gene_synonym="5730593F17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..2317
                     /gene="Fam117a"
                     /gene_synonym="5730593F17Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2298..2303
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam117a"
                     /gene_synonym="5730593F17Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2317
                     /gene="Fam117a"
                     /gene_synonym="5730593F17Rik"
                     /note="major polyA site"
ORIGIN      
        1 agtgtggggc tcgccgtggg ggtgaggcgg caggtagccg ggtgggccat gtccggggcc
       61 gcagcgggcg gccgaggcgg aggttcctgg gggccggggc gcggaggggc ggggggtctc
      121 cggcggggct gctctccacc ggcgcccgct ggctcccccc gggtcggtct gcagccactc
      181 agggctacgg tccccttcca gctgcagcag cctcaccagc gccgggacgg gggtggccgc
      241 gcagccagcg ttccatgttc ggtggcccca gaaaagtcgg tgtgtaggcc tcagccaccc
      301 caggtccggc gtacgttctc cctggacacc atcctcagtt cctaccttct gggccagtgg
      361 ccacgagatg ccgatggggc cttcacctgc tgtaccaatg acaaggccac ccagacaccc
      421 ctgtcctggc aagaaccaga aggtgagcgg gccagcttct gcatgcacaa gcggtcagca
      481 tcgtggggca gcacagacca ccgaaaagag atcaccaagt tgaagcagca gctgcagagg
      541 acaaaactga gccgcagtgg gaaggagaag gagcggagct gccctgtcca aggggaccat
      601 gctgcgctgg gagcagggag ggcatccctt cccagccacc ccccaggacc ccccgtcctg
      661 cgactcagcc cttgtctgca cagaagccta gaagggctca accaggagct ggaagaggtg
      721 tttgtgaagg agcagggtga agaggagctg ctgaggatac ttgaggtccc tgatgggcac
      781 cgtgccccag ctcctccaca gaatagcagc tgtgaccatt ccctcctttt ggagccaggc
      841 aacctgacca gctctccctc cgtgccactg gcatcccccc agcctcccag ccaggccagc
      901 cgtgaggagc accagggtgc caccgaggaa ctagcatcca tccacggtaa caaagcctcc
      961 tctccaggca acccagcctt cctagaagat ggcagtccgt ctccagtcct tgcctttgct
     1021 gcttcccctc ggcccaatca cagctacgtc ttcaaacggg agcccccaga aggctgtgag
     1081 agagtgcgtg tgtttgagga ggccacgtcc ccaggtcctg acttggcctt cttgacttcc
     1141 tgtcctgaca agaacaaagt ccatttcaac ccgactggct ccgccttctg ccctgtcagc
     1201 ttgatcaagc ccctcttccc cagtatgggc ttcatcttcc gtaactgccc ctccagccct
     1261 ggctcccctc ttcccactgc cagccccagg gcacctcgga agggtccaga agcttccaag
     1321 gcctcctcgc tgccatctga gccatggcag cgcagcccac catcggaaga gtctgtgctt
     1381 ttccagagct ccttggtagt ctgagtcccc caggccccta ccacacttta ccatggagac
     1441 tagtgccttg gtggcaagct ctttgttagc ttcccaagct gggggatgga ggagcccttc
     1501 cttccctctt ggcctttgag cactttcctt tattgtgtca aagccccagg tcctttggtg
     1561 gacatcagcc ctccacaggg aggagactta cctcctccac cagcagcagg cagctcacaa
     1621 cttacacttg tgtacctgcg gtttccctca cctgccagaa ggtcttgaat cttctagccc
     1681 agggtgtgag tccagatgac ttataagagg ctcttgtcat ggaacagttg gctgtggcta
     1741 agagagggga ggtgccacag gcttcctgac agctccactc tagagacaca gaaaggcaga
     1801 ccagatgcct ccctcctaga ggagttgacc agagtggccc tcagggccag aacacttgac
     1861 caatcagctg ttggcagggg accatgagat ttcccaagtg gcattttcat ctcagtttta
     1921 ccctgactaa agattgtctt aggggaatcc caacccaaag tgaatagtgg gaagaggggt
     1981 ctggcattcc ttcagggggc atgcagcagc cccgtactcg ccacctgccc cagggggcat
     2041 gagcagctcc atgccctcta cccaccccaa ggttgggttg aattagaaaa atgcctattt
     2101 ttcttgtatc gatgtagaaa ctctattttc tcccaaagac actatttttg cagctatttg
     2161 aagtttgtat attttccgta ttgcagagct tacacaaaat tgaagaatgt taatgttcaa
     2221 ggtttcatat cttgtgttta gaggttattg tggtttttgt ttgtttattt tttgcagatc
     2281 ttgattttaa tagaccaaat aaatatgtat tccagcaaaa aaaaaaaaaa aaaa
//
