LOCUS       NM_026342               2590 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus family with sequence similarity 114, member A2
            (Fam114a2), transcript variant 2, mRNA.
ACCESSION   NM_026342 NM_027408
VERSION     NM_026342.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2590)
  AUTHORS   Khan,A., Yuewen,W., Dil,S., Shah,W., Shi,Q. and Khan,R.
  TITLE     The evolutionarily conserved gene, Fam114a2, is dispensable for
            fertility in mouse
  JOURNAL   Reprod Biol 21 (3), 100531 (2021)
   PUBMED   34315090
  REMARK    GeneRIF: The evolutionarily conserved gene, Fam114a2, is
            dispensable for fertility in mouse.
REFERENCE   2  (bases 1 to 2590)
  AUTHORS   Vincentz,J.W., Firulli,B.A., Toolan,K.P., Arking,D.E.,
            Sotoodehnia,N., Wan,J., Chen,P.S., de Gier-de Vries,C.,
            Christoffels,V.M., Rubart-von der Lohe,M. and Firulli,A.B.
  TITLE     Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA
            Transcription Factor Binding and Disrupts Conduction System
            Development and Function
  JOURNAL   Circ Res 125 (6), 575-589 (2019)
   PUBMED   31366290
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY134675.1, AK018570.1 and AL672236.18.
            
            On Dec 15, 2009 this sequence version replaced NM_026342.2.
            
            Transcript Variant: This variant (2) differs in the 5' UTR and uses
            an alternate in-frame splice site in the coding region, compared to
            variant 1. This results in a shorter protein (isoform 2), compared
            to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK018570.1, SRR7652917.1028048.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                BY134675.1         1-29
            30-80               AK018570.1         2-52
            81-2580             AK018570.1         54-2553
            2581-2590           AL672236.18        132447-132456       c
FEATURES             Location/Qualifiers
     source          1..2590
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 35.27 cM"
     gene            1..2590
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /note="family with sequence similarity 114, member A2"
                     /db_xref="GeneID:67726"
                     /db_xref="MGI:MGI:1917629"
     exon            1..72
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            73..269
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            270..369
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            370..462
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            463..551
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            552..686
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            687..845
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            846..969
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            970..1049
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..1172
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1173..1312
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1313..1385
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1439
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..2590
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2562..2567
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /note="hexamer: AATAAA"
     regulatory      2573..2578
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /note="hexamer: ATTATA"
     polyA_site      2582
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
                     /note="major polyA site"
     polyA_site      2590
                     /gene="Fam114a2"
                     /gene_synonym="1810073G14Rik; 9030624B09Rik"
ORIGIN      
        1 gcctccgcgc tgaggtcagg agtacttccg cgacggtcgg gtcggatcgg cgagcgagcg
       61 gcggtggccg cgcaggcgat gttgtagtca tgtcagataa ggatcctcca gagtctccag
      121 tggtaaccgg agtagcttcg acccttaaag atgagaactg tgagccagtg gagaagccag
      181 aggataaatc tcagcctgta gtgtccaccc ggaaaagacc agagaccaaa ccttccagtg
      241 accttgaggc ttctgctctt cctgctcagg agactgcttc taaagatgta cctcagactg
      301 ggtggggtta ttggggcagt tggggcaagt ctctgctctc ctcagcctca gctacggtag
      361 ctacagtagg acaaggtatt tcaaatgtca ttgagaaggc agagacttct cttgggattc
      421 ctagccccac tgaaatttca gctgaagtca agcaagcagc aggagaaaaa aatgctggtg
      481 agaatggaag cttactagtg gctgcaccat tcgggatgct ctcgaccatc tctacagctg
      541 tgcagagcac gggcaagagc gttatcagtg ggggcttgga tgccttggaa ttcattggga
      601 agaagacaat ggatgtcata gcagaagggg accctggatt taaaagaacc aagggcctga
      661 tgaatcggac ttctacgctg tctcaggttt tacgagaggc aaaggataaa gaagagcagc
      721 ggccttccaa tgaagtaacc atggaaacag acaagaaaac tcattatggg ctactctttg
      781 atgagtttca aggcctttca catctagaag ctctggagat gctttcccga gaaagtgaga
      841 taaaggtgaa atctattctt agttctctga gtggagaaga actacagaca actagacttg
      901 agctagagca gctcaaagaa gtgttttccc tagcagagtt ctgtgaggaa gaggaggagg
      961 agagacaagg ggatgacaat tttaccaagg agataacaga tctgtttgct cagcttcacg
     1021 tctcctcccg accagagaag cttgccaggg caagaaatac agcctacaaa tggatcagaa
     1081 catctctggc taggccagta gcagagaaag aagaaggaga aaaagagtcg gaggcaggaa
     1141 ataccgagga agcccagaaa cattcaatag aggatatcca tgcatttgca atccggagct
     1201 tagcagagtt gactgcctgc tcaatagaat tgttccacaa aacagcagca ttggttttgc
     1261 atggccagaa gcaggaggtg acagccttag agaggagcca gactctctcc cagatgacag
     1321 tcatgctgtg taaagacctg gcctcgctgt ctaaagagtt caccacctgc ctgaccacag
     1381 ctggggtcag agagaaggca gatgttctta atccagtcat cactgcagtg tttctagagg
     1441 cctcaaacag cgcctcttac attcaagatg ccttccaact cctcctgcct gtgctgcaga
     1501 tctctctcat cgagagcaag acagagtcat ccacgtgtga gccacagtcc agagacctct
     1561 gacagaaccc tgaggagcag agaagagtcc tactgagatg gtgatagcca agaaatctga
     1621 ctttgctcag ggagccctgc agccagagcg aggcatagta ctacgtgtgt gaaaggccag
     1681 cagggcgcag gctcacaggg gtgcttgctt ctctgcgtag ctgatgcgct ctgctgctca
     1741 cactgctctt ccagccttat aagtaataaa ttattaaaaa aaaaaaaaga aagaaagaaa
     1801 gaagaaaaac caaatgtatt tcaggaaagt cagcaggata ttctggcaaa aatgctggac
     1861 tttcttagct cagaaaacac tatagactgt tatggatgtc atttgcagcc agtggtaaaa
     1921 ttgttaagca ggagagaaca aaacctcagt ttggtgtcct ggggtttatg acattcgtcg
     1981 tagcctgggc tttctccttt ccagaataaa gcctgtggct tctagagaac tgagactaca
     2041 ttagccctaa gtgagatggc cggacagggc tgtctagatg tttcgcatgg agtagaaact
     2101 cgtagccgtg tgtatgaacc acagggaaat gccctttggc ttcaaatgcc tctcttccca
     2161 gtagaccatg cagtctgcag gtgctctgag tctcttcagg ctgcattgtg catgccctgc
     2221 ctgaggctgc actcatgcag gcacatcttt cagctgccaa ctccagagca ggagggagga
     2281 gtcttttggt gatggggttt tgtggagtcc tgtgaagatg ttcacttaca gcaggatgta
     2341 gcctcccaag tcccctcatt gttcctctgt tgtcgtgtgt ttgttactgt gcttggagag
     2401 gagctcacct gccgtccgta ctctcgagcc ctcctcgcag ttttcagcag ttcaaagcta
     2461 ttttggtatc caggcctttt gaaaatgttc attaactttg tgatttttag tggctccggc
     2521 aactttggag agccctgttc tttatctttg aaaaccatta caataaaata taattatacc
     2581 tactttataa
//
