LOCUS       NM_026667               2881 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus family with sequence similarity 114, member A1
            (Fam114a1), mRNA.
ACCESSION   NM_026667
VERSION     NM_026667.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2881)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2881)
  AUTHORS   Subbaiah,K.C.V., Wu,J., Tang,W.H.W. and Yao,P.
  TITLE     FAM114A1 influences cardiac pathological remodeling by regulating
            angiotensin II signaling
  JOURNAL   JCI Insight 7 (13), e152783 (2022)
   PUBMED   35671117
  REMARK    GeneRIF: FAM114A1 influences cardiac pathological remodeling by
            regulating angiotensin II signaling.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2881)
  AUTHORS   Zhou,M., Lin,F., Wu,X., Ping,Z., Xu,W., Jin,R. and Xu,A.
  TITLE     Inhibition of Fam114A1 protects melanocytes from apoptosis through
            higher RACK1 expression
  JOURNAL   Aging (Albany NY) 13 (22), 24740-24752 (2021)
   PUBMED   34837888
  REMARK    GeneRIF: Inhibition of Fam114A1 protects melanocytes from apoptosis
            through higher RACK1 expression.
REFERENCE   4  (bases 1 to 2881)
  AUTHORS   Zhang,W., Thevapriya,S., Kim,P.J., Yu,W.P., Je,H.S., Tan,E.K. and
            Zeng,L.
  TITLE     Amyloid precursor protein regulates neurogenesis by antagonizing
            miR-574-5p in the developing cerebral cortex
  JOURNAL   Nat Commun 5, 3330 (2014)
   PUBMED   24584353
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2881)
  AUTHORS   Boucquey,M., De Plaen,E., Locker,M., Poliard,A.,
            Mouillet-Richard,S., Boon,T. and Kellermann,O.
  TITLE     Noxp20 and Noxp70, two new markers of early neuronal
            differentiation, detected in teratocarcinoma-derived
            neuroectodermic precursor cells
  JOURNAL   J Neurochem 99 (2), 657-669 (2006)
   PUBMED   17029606
  REMARK    GeneRIF: The Noxp20 transcript encodes a putative protein with a
            predicted caspase recruitment domain. At embryonic days 12 and 15,
            Noxp20 is strongly expressed in the ventricular and intermediate
            zones of the brain and of the spinal cord.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161757.5 and AC124428.4.
            
            On Dec 29, 2021 this sequence version replaced NM_026667.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AM162548.1, BC027235.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                AC161757.5         41518-41546         c
            30-385              AC161757.5         31599-31954         c
            386-473             AC161757.5         15760-15847         c
            474-587             AC161757.5         5751-5864           c
            588-697             AC161757.5         5519-5628           c
            698-832             AC161757.5         2540-2674           c
            833-985             AC124428.4         55461-55613         c
            986-1109            AC124428.4         49204-49327         c
            1110-1201           AC124428.4         42428-42519         c
            1202-1363           AC124428.4         40703-40864         c
            1364-1503           AC124428.4         39535-39674         c
            1504-1576           AC124428.4         36485-36557         c
            1577-1630           AC124428.4         32188-32241         c
            1631-2881           AC124428.4         29055-30305         c
FEATURES             Location/Qualifiers
     source          1..2881
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 33.55 cM"
     gene            1..2881
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /note="family with sequence similarity 114, member A1"
                     /db_xref="GeneID:68303"
                     /db_xref="MGI:MGI:1915553"
     exon            1..29
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /inference="alignment:Splign:2.1.0"
     exon            30..385
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..1747
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /note="nervous system over-expressed protein 20; nervous
                     system overexpressed protein 20"
                     /codon_start=1
                     /product="protein Noxp20"
                     /protein_id="NP_080943.3"
                     /db_xref="CCDS:CCDS19304.1"
                     /db_xref="GeneID:68303"
                     /db_xref="MGI:MGI:1915553"
                     /translation="MSDDARDTIANGVGEDAAEMPNSDSPAEDAAEVQCGPATTSNEP
                     APDDHMEEQPEITAMCAESTPPGILDQSKASAADETPLNGEVTEDTLVECVDSVSLEG
                     DTGSEIPLKEQDDAAVDPSSQAGRWAGWGSWGKSLLSSASATVGHGLTAVKEKAGATL
                     RIHSANSASPEGAPTDAENGISGNVTPDQDPARGPHTPPPPGAAGSRGMLSALTNVVQ
                     NTGKSVLTGGLDALEFIGKKTMIVLAESDPGFKRTKTLMERTVSLSQMLREAKEKEKQ
                     RLAQQLTVERTAHYGMLFDEYQGLSHLEALEILSNESESKVQSFLTSLDGEKLELLKN
                     DLISIKDIFVAKESENEANPEEQGLEESGEEFARMLTELLFELHVAATPDKLNKAMKK
                     AHDWVEEDQSVVSIDVAKGSEEEEKEEGKEEKAEEPEEDKTGGQGAKTVEEVYMLSIE
                     SLAEVTARCIEQLHKVAELILHGQEEEKPAQDQARVLIKLTTAMCNEVTSLSKKFTNS
                     LTTVGSNKKAEVLNPMINSVFLEGSNSTTYVQDALQLLLPVLQVSHIRTSCLKATAQP
                     DCS"
     exon            386..473
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /inference="alignment:Splign:2.1.0"
     exon            474..587
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /inference="alignment:Splign:2.1.0"
     exon            588..697
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /inference="alignment:Splign:2.1.0"
     exon            698..832
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /inference="alignment:Splign:2.1.0"
     exon            833..985
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /inference="alignment:Splign:2.1.0"
     exon            986..1109
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /inference="alignment:Splign:2.1.0"
     exon            1110..1201
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /inference="alignment:Splign:2.1.0"
     exon            1202..1363
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /inference="alignment:Splign:2.1.0"
     exon            1364..1503
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /inference="alignment:Splign:2.1.0"
     exon            1504..1576
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /inference="alignment:Splign:2.1.0"
     exon            1577..1630
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /inference="alignment:Splign:2.1.0"
     exon            1631..2881
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2135..2140
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /note="hexamer: CATAAA"
     polyA_site      2155
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /note="major polyA site"
     regulatory      2837..2842
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /note="hexamer: AATAAA"
     polyA_site      2881
                     /gene="Fam114a1"
                     /gene_synonym="1190001N04Rik; 9130005N14Rik; Noxp20"
                     /note="major polyA site"
ORIGIN      
        1 actcccgcgc gcactcggcc ggccaagcga tattaaaatg tctgatgatg ctcgtgacac
       61 catagccaat ggagtcggag aagatgctgc tgagatgccc aacagtgact cccctgctga
      121 agatgcagca gaagtgcagt gtggtccagc tacaacttca aatgaaccag caccagatga
      181 ccacatggaa gagcagcctg agatcacagc tatgtgtgca gagtccaccc ctccagggat
      241 tctagaccaa tccaaggcca gtgctgccga cgagaccccc ctcaatggag aagtaactga
      301 agacaccctg gttgagtgcg ttgattccgt cagcctcgag ggagacaccg gatctgaaat
      361 acctctgaaa gaacaggatg acgcggctgt ggacccctca tcacaggcag gaagatgggc
      421 aggctgggga tcctggggga aatctctgct ctcatctgca tcagccacag taggtcatgg
      481 attaacagca gtcaaagaaa aggcaggggc aaccctacga atccacagtg ccaattctgc
      541 atctcccgaa ggggccccaa ctgatgctga aaacggaatc tctggaaatg tgactccaga
      601 tcaggaccct gccagaggcc cccacactcc tcctccacca ggggcggcag ggtcgagagg
      661 catgctgtca gccctcacca atgtggttca aaacacgggc aaaagcgtct taaccggagg
      721 tctggatgct ttagaattca ttggcaagaa aaccatgatt gtcctcgcag aaagcgaccc
      781 agggtttaag cggaccaaga cactgatgga acgaactgtc tccttgtccc agatgttgag
      841 agaagccaag gagaaggaga agcagaggtt ggcccagcag ctcacagtgg agaggactgc
      901 acactatggg atgctgtttg atgaatatca aggtttgtca cacctggaag ccctggaaat
      961 tctgtccaat gagagtgaga gcaaggttca gtccttctta acatccctgg atggagagaa
     1021 gctagaactc ttgaaaaatg acctaatttc aatcaaggac atctttgtag ccaaagaatc
     1081 agagaatgaa gcaaacccag aagaacaagg cctagaagaa agcggggaag aatttgccag
     1141 gatgcttaca gagctcctgt ttgaattaca cgtcgccgcc acacctgaca aactcaataa
     1201 ggccatgaag aaagctcatg actgggtgga agaagatcaa agcgtggtgt cgatagatgt
     1261 ggccaaaggg tcggaggagg aagagaagga agaaggaaag gaagagaaag ccgaagaacc
     1321 tgaagaagac aaaacagggg gccaaggagc taagactgta gaggaagtgt acatgctgtc
     1381 cattgaaagt ctggctgaag tcactgcacg ctgcattgaa cagctacata aggttgcaga
     1441 gttgattctc catggacaag aggaggagaa accagctcaa gaccaagcaa gagttctgat
     1501 aaaattaacc acagcaatgt gcaatgaagt aacctcctta tcgaagaagt ttacaaattc
     1561 tttaaccact gttgggagca acaagaaggc tgaagtcctt aaccccatga tcaatagtgt
     1621 gtttttagag ggctccaata gcaccacata tgtgcaggac gccctccagc tgctgctccc
     1681 ggtactgcag gtctcccaca tccgcaccag ctgtttgaaa gctacagccc agccagattg
     1741 cagctagttc aatagcaggc cacatctctt cactacatac catttaaagg caacggactt
     1801 ctatgtcact ggccagacca tttgaggaca ctacaagcaa tttttgcaca gttttgaaaa
     1861 tacagagagt taaaatttct cttaatgtat actgttttat caataattat gttttcttta
     1921 cattaactta aacttgtact tgttctattg aagttttcct ttaatttgca gttcattcac
     1981 aaatatatct gttttcctgg tcaaccagac tatatttaga aattcataga gagaacctag
     2041 atttttgttc agctttgaaa tgtctacctt tctatgccct atttttctca agcatggctt
     2101 taaatgagtt cttgtactga acttcattta attgcataaa catcataagc aaaaataccg
     2161 ctacttattt ggttttaaaa gggacataaa tatctttata aatatcacta tgtagaccag
     2221 gctagcctaa aactcacaaa gatctgcctg cctctgcctc ccaagaacta ggactaaagg
     2281 tgtgcacacg aaacctgcct gccctgaaga agtgttttag tttagagtgt ttggtggcaa
     2341 aattataaag ctgagaatca tttcaacaga aaactaaagg ggttttagcc aggtagaaac
     2401 cccgacctgc atttcaaaaa tacccactaa cctgatcaca cacatggtag aggcaaaggg
     2461 tagaaagtcg taagttggcc aagtggggtg ctgatccagg gagatgcatc agagaccttg
     2521 cagggagcag tggtactgaa cctgggctct tgtgagatgc atctgttctt tccaggctga
     2581 ggttctctgg catgcttctg tttgagacca tcactgacat ccctaccagt agtgtccaaa
     2641 atagtcatgc ccagtggctt atcccagggc aaatgatgcc tgcagtcttg aaagggagaa
     2701 aaatccctcc tttgttcctg tggtagaagc cactgcgtct gtcccctgtg ggccaagtag
     2761 atatctgaat tctctcagta gcatttttgt gtgactgtgt tttgtttttt cagctgtatg
     2821 tctcctgaaa caaccaaata aaaactcaag aacaatgtat ttgcaaccta gaaaaattaa
     2881 a
//
