LOCUS       NM_026640               3199 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus family with sequence similarity 111, member A
            (Fam111a), transcript variant 1, mRNA.
ACCESSION   NM_026640
VERSION     NM_026640.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3199)
  AUTHORS   Ilenwabor,B.P., Schigt,H., Kompatscher,A., Bos,C.,
            Zuidscherwoude,M., van der Eerden,B.C.J., Hoenderop,J.G.J. and de
            Baaij,J.H.F.
  TITLE     FAM111A is dispensable for electrolyte homeostasis in mice
  JOURNAL   Sci Rep 12 (1), 10211 (2022)
   PUBMED   35715480
  REMARK    GeneRIF: FAM111A is dispensable for electrolyte homeostasis in
            mice.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3199)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   3  (bases 1 to 3199)
  AUTHORS   VanBuren,V., Piao,Y., Dudekula,D.B., Qian,Y., Carter,M.G.,
            Martin,P.R., Stagg,C.A., Bassey,U.C., Aiba,K., Hamatani,T.,
            Kargul,G.J., Luo,A.G., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Assembly, verification, and initial annotation of the NIA mouse
            7.4K cDNA clone set
  JOURNAL   Genome Res 12 (12), 1999-2003 (2002)
   PUBMED   12466305
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK019499.1.
            
            On Apr 6, 2007 this sequence version replaced NM_026640.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK019499.1, AK172402.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849390, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3199              AK019499.1         2-3200
FEATURES             Location/Qualifiers
     source          1..3199
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 8.72 cM"
     gene            1..3199
                     /gene="Fam111a"
                     /gene_synonym="4632417K18Rik"
                     /note="family with sequence similarity 111, member A"
                     /db_xref="GeneID:107373"
                     /db_xref="MGI:MGI:1915508"
     exon            1..56
                     /gene="Fam111a"
                     /gene_synonym="4632417K18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            57..137
                     /gene="Fam111a"
                     /gene_synonym="4632417K18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            138..337
                     /gene="Fam111a"
                     /gene_synonym="4632417K18Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             260..2101
                     /gene="Fam111a"
                     /gene_synonym="4632417K18Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein FAM111A; serine protease FAM111A"
                     /codon_start=1
                     /product="serine protease FAM111A isoform 1"
                     /protein_id="NP_080916.1"
                     /db_xref="CCDS:CCDS29632.1"
                     /db_xref="GeneID:107373"
                     /db_xref="MGI:MGI:1915508"
                     /translation="MSCKKRKSQISFNPRKNKKIKDYFSQVPKEEQNDPNTVKVDSKK
                     MPRDITNTRDQRPLSPRKTRQDQTPPLNKKITVTLGVNSRKHKNMKYELTCRETSSLY
                     AALNTLSAVREEVESQKGREMLVCGKEGIEGYLNLGMPVCCIPEGSHVVITFCQCKSK
                     TQENKQFFESQDQASTNYVRFCIHAVGSKRKKILKCGELQKEGNKLCVYGFKGETIRD
                     TLRKDGRFCTFIESDDWKLINDLDTIIENTQPVDELEGKLFQVAAELPKNPRVVSVTQ
                     NSGSENRNFHKLEEYIVNEYTTLKEEGKKLRAYIKEKSEKRKKKASLFKVHKEHFGKM
                     TRNSTPVKVVKHLSRVSDSVGFLWWNNNGNAGCATCFVFKELYILTCQHVIASIVGEG
                     IDSSEWANIISQCVKVTFDYEELLPTGDKFFMVKPWFEISDKHLDYAVLELKENGQEV
                     PAGLYHRIRPVPHSGLIYIIGHPEGEKKSIDCCTVVPQSSRRKKCQENFQAREEAGFC
                     FSTSFIHMYTQRSFQEMLHNSDVVTYDTSFFGGSSGSPVFDSNGSLVAMHAAGITCTY
                     QAGVSNIIEFGSIMESIDDHMKQDKYKEWYNTISGNVQNVEMLSIDF"
     exon            338..3199
                     /gene="Fam111a"
                     /gene_synonym="4632417K18Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3150..3155
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam111a"
                     /gene_synonym="4632417K18Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3187
                     /gene="Fam111a"
                     /gene_synonym="4632417K18Rik"
                     /note="major polyA site"
ORIGIN      
        1 aaaagacccg ggattccagc ggctggagcg aagctgccat agagtggaaa gatccaacca
       61 ctactcagtt ctcttcatgc ctgtttgcct ggccttatca tctccatttt aaaccaacag
      121 cagatattaa catcagtgtt gaggacgaag cccaggcctt gcaattgcta gtctaccact
      181 gaactaaatt tccaacccaa cttaaaccat tttggagttt gagtttcagc tgagccatct
      241 atttcatctc taagccaaaa tgagctgtaa gaagcggaaa tcacagatct catttaatcc
      301 aaggaaaaat aaaaaaatta aggactattt ctctcaggtc cccaaagaag agcagaatga
      361 ccccaacaca gtaaaagtgg actctaaaaa aatgccaagg gatataacca acaccaggga
      421 ccaaagacca ctttcaccca ggaaaactcg acaagatcag actcctcccc taaataagaa
      481 aatcacagta accttgggtg tgaactctag gaaacacaaa aacatgaaat atgagctcac
      541 gtgtagggag acaagcagct tgtatgcagc actcaacact ctcagtgctg tcagagaaga
      601 ggtagaaagt caaaagggca gagaaatgct ggtgtgtggc aaagaaggaa ttgaagggta
      661 cttaaacctt ggcatgcccg tctgctgtat accagaaggc agccatgtcg tcattacatt
      721 ttgtcaatgt aaaagtaaga cacaggaaaa taaacaattc tttgaatcac aggaccaagc
      781 atctaccaat tacgtccgat tttgcattca tgcagttggg agtaagagga aaaagattct
      841 gaagtgtgga gaacttcaga aagaggggaa caaactctgt gtctatggct tcaaaggaga
      901 gaccatcagg gacactctga ggaaggatgg caggttttgt actttcatag agagtgacga
      961 ttggaaactc attaatgacc tggacaccat catagaaaac acacagccag ttgatgagtt
     1021 agagggcaag ctttttcagg ttgcagctga gctaccaaag aaccccagag tagtctctgt
     1081 cactcagaat tctgggtcag agaacagaaa ctttcataag ctagaagagt acattgtgaa
     1141 tgagtacact acattgaaag aagaaggaaa aaaacttaga gcatacatca aggaaaaaag
     1201 tgaaaaaagg aagaagaaag cttccttatt caaagtgcat aaagaacact ttgggaaaat
     1261 gacaagaaat tctactcctg ttaaagtggt caaacatctt tcgagggtca gtgactcagt
     1321 tgggttccta tggtggaaca acaatggaaa tgcaggctgt gccacctgct ttgtttttaa
     1381 agagttgtac attttgactt gtcagcatgt gatagctagc attgtgggtg aaggcataga
     1441 ttcaagtgag tgggcaaaca taattagtca gtgtgtaaag gtgacctttg attatgaaga
     1501 gttactacca acaggagaca agttttttat ggttaaacct tggtttgaaa tatctgataa
     1561 acaccttgac tatgctgtcc tggaactgaa ggaaaatgga caagaagtac ctgctgggct
     1621 gtatcataga ataagacctg tgccacatag tgggttgatt tatatcattg gccatcctga
     1681 gggagaaaag aagtctattg attgctgtac agtggtccct caaagtagta gaagaaaaaa
     1741 atgtcaggaa aattttcaag caagagagga agcaggcttc tgtttttcta catcttttat
     1801 ccatatgtac acacaaagaa gtttccagga aatgcttcac aactctgatg tggttactta
     1861 tgacaccagt ttttttggtg ggtcttctgg atccccagta tttgattcta atggttcatt
     1921 ggtggccatg catgctgctg gcatcacttg tacataccag gctggagttt ccaatatcat
     1981 tgagtttggt tctattatgg aatccattga tgatcatatg aagcaagata aatataaaga
     2041 gtggtataac acaatttctg gaaatgttca gaatgtagaa atgctgagca tagatttctg
     2101 agggctggaa agggtttagt cttttaaaac tttaagggaa ttgcctattg tgtttttctg
     2161 cagacaataa tgttttatga agtttcaaaa tgattgcttt caccccaaaa tggcagttct
     2221 agattacgtc ctaggtacca ggcattttta gtttattcaa acaaacaaac aaacaaacca
     2281 agacaaaacc atcaattgaa ctatttatgt aaggtaacat ggaaaagaaa attaagtgct
     2341 aatgtggtct cggagatcct agtgtcagga aatgctacga tgtgagaaag ttcagagcat
     2401 agaaactgga gttgttggcc aaaagattca tggaaaaaaa gaagcctacc atgcttctgg
     2461 aaacttgaac caatttcaaa catactcatt tggttctacg cttatctccc ttctctgctg
     2521 accagagctc agccaggaca ctggatcaca gagttttcag ccctaagatg cccctgatca
     2581 tagatgccct tcttccactt tggctttctt acttaagact tggatctgaa attaaccttc
     2641 aaggaatggt tttggaaatc attgagcagg caaggaactg gtctctgcca tagaatttgt
     2701 gcacctgaga gttcctggtc ttgagttatg gagagcaagc actggtttct acttcatagg
     2761 attcacaatg gagagggcta ggaagatact ggacaatttt cagcagtgtg acactcaagt
     2821 cctggtccct tggagagaaa ggacgcggtg ttcaagaagt aatctcatca aaatcagagt
     2881 caatgagacc ttacatacag aagacatgag gtcttagatt attggaggga aagtggaacg
     2941 agtagttgag atgctgaggg aaggttgcta agagatctgg cattgcttca attcttccct
     3001 tatcagaacg aaatatgtcc tgtgttagag ctagcatgat cgcaagccac aactcccctt
     3061 attttccaga cacctcctag tcctattgtg agatattttg tgtcccctgc ccaatgtatt
     3121 gttcccaaat caaatacaga tgaatcacca ttaaacatag tgaattttga gatacaaatt
     3181 aaaaaaatta tttgtatgg
//
