LOCUS       NP_080916                613 aa            linear   ROD 02-JUN-2024
DEFINITION  serine protease FAM111A isoform 1 [Mus musculus].
ACCESSION   NP_080916
VERSION     NP_080916.1
DBSOURCE    REFSEQ: accession NM_026640.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 613)
  AUTHORS   Ilenwabor,B.P., Schigt,H., Kompatscher,A., Bos,C.,
            Zuidscherwoude,M., van der Eerden,B.C.J., Hoenderop,J.G.J. and de
            Baaij,J.H.F.
  TITLE     FAM111A is dispensable for electrolyte homeostasis in mice
  JOURNAL   Sci Rep 12 (1), 10211 (2022)
   PUBMED   35715480
  REMARK    GeneRIF: FAM111A is dispensable for electrolyte homeostasis in
            mice.
            Publication Status: Online-Only
REFERENCE   2  (residues 1 to 613)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   3  (residues 1 to 613)
  AUTHORS   VanBuren,V., Piao,Y., Dudekula,D.B., Qian,Y., Carter,M.G.,
            Martin,P.R., Stagg,C.A., Bassey,U.C., Aiba,K., Hamatani,T.,
            Kargul,G.J., Luo,A.G., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Assembly, verification, and initial annotation of the NIA mouse
            7.4K cDNA clone set
  JOURNAL   Genome Res 12 (12), 1999-2003 (2002)
   PUBMED   12466305
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK019499.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK019499.1, AK172402.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849390, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..613
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 8.72 cM"
     Protein         1..613
                     /product="serine protease FAM111A isoform 1"
                     /note="protein FAM111A; serine protease FAM111A"
                     /calculated_mol_wt=69818
     Region          1..72
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9D2L9.1)"
     Site            25
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q96PZ2; propagated from
                     UniProtKB/Swiss-Prot (Q9D2L9.1)"
     Site            331..332
                     /site_type="cleavage"
                     /note="Cleavage, by autolysis.
                     /evidence=ECO:0000250|UniProtKB:Q96PZ2; propagated from
                     UniProtKB/Swiss-Prot (Q9D2L9.1)"
     Region          368..557
                     /region_name="Trypsin_2"
                     /note="Trypsin-like peptidase domain; pfam13365"
                     /db_xref="CDD:433149"
     CDS             1..613
                     /gene="Fam111a"
                     /gene_synonym="4632417K18Rik"
                     /coded_by="NM_026640.2:260..2101"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS29632.1"
                     /db_xref="GeneID:107373"
                     /db_xref="MGI:MGI:1915508"
ORIGIN      
        1 msckkrksqi sfnprknkki kdyfsqvpke eqndpntvkv dskkmprdit ntrdqrplsp
       61 rktrqdqtpp lnkkitvtlg vnsrkhknmk yeltcretss lyaalntlsa vreevesqkg
      121 remlvcgkeg iegylnlgmp vccipegshv vitfcqcksk tqenkqffes qdqastnyvr
      181 fcihavgskr kkilkcgelq kegnklcvyg fkgetirdtl rkdgrfctfi esddwklind
      241 ldtiientqp vdelegklfq vaaelpknpr vvsvtqnsgs enrnfhklee yivneyttlk
      301 eegkklrayi keksekrkkk aslfkvhkeh fgkmtrnstp vkvvkhlsrv sdsvgflwwn
      361 nngnagcatc fvfkelyilt cqhviasivg egidssewan iisqcvkvtf dyeellptgd
      421 kffmvkpwfe isdkhldyav lelkengqev paglyhrirp vphsgliyii ghpegekksi
      481 dcctvvpqss rrkkcqenfq areeagfcfs tsfihmytqr sfqemlhnsd vvtydtsffg
      541 gssgspvfds ngslvamhaa gitctyqagv sniiefgsim esiddhmkqd kykewyntis
      601 gnvqnvemls idf
//
