LOCUS       NM_010174                680 bp    mRNA    linear   ROD 24-SEP-2024
DEFINITION  Mus musculus fatty acid binding protein 3, muscle and heart
            (Fabp3), mRNA.
ACCESSION   NM_010174
VERSION     NM_010174.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 680)
  AUTHORS   Farley,A., Gao,Y., Sun,Y., Zohrabian,S., Pu,W.T. and Lin,Z.
  TITLE     Activation of VGLL4 Suppresses Cardiomyocyte Maturational
            Hypertrophic Growth
  JOURNAL   Cells 13 (16), 1342 (2024)
   PUBMED   39195232
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 680)
  AUTHORS   Xu,Y., Sun,B., Wang,H., Cai,Y., Chu,D., Cao,R. and Wang,Z.
  TITLE     Autophagy regulates age-related delayed jawbone regeneration and
            decreased osteoblast osteogenesis by degrading FABP3
  JOURNAL   FASEB J 38 (14), e23824 (2024)
   PUBMED   39012304
  REMARK    GeneRIF: Autophagy regulates age-related delayed jawbone
            regeneration and decreased osteoblast osteogenesis by degrading
            FABP3.
REFERENCE   3  (bases 1 to 680)
  AUTHORS   Zhong,F.F., Wei,B., Bao,G.X., Lou,Y.P., Wei,M.E., Wang,X.Y.,
            Xiao,X. and Tian,J.J.
  TITLE     FABP3 Induces Mitochondrial Autophagy to Promote Neuronal Cell
            Apoptosis in Brain Ischemia-Reperfusion Injury
  JOURNAL   Neurotox Res 42 (4), 35 (2024)
   PUBMED   39008165
  REMARK    GeneRIF: FABP3 Induces Mitochondrial Autophagy to Promote Neuronal
            Cell Apoptosis in Brain Ischemia-Reperfusion Injury.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 680)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   5  (bases 1 to 680)
  AUTHORS   Bernheim,S., Borgel,A., Le Garrec,J.F., Perthame,E., Desgrange,A.,
            Michel,C., Guillemot,L., Sart,S., Baroud,C.N., Krezel,W.,
            Raimondi,F., Bonnet,D., Zaffran,S., Houyel,L. and Meilhac,S.M.
  TITLE     Identification of Greb1l as a genetic determinant of crisscross
            heart in mice showing torsion of the heart tube by shortage of
            progenitor cells
  JOURNAL   Dev Cell 58 (21), 2217-2234 (2023)
   PUBMED   37852253
REFERENCE   6  (bases 1 to 680)
  AUTHORS   Binas,B., Spitzer,E., Zschiesche,W., Erdmann,B., Kurtz,A.,
            Muller,T., Niemann,C., Blenau,W. and Grosse,R.
  TITLE     Hormonal induction of functional differentiation and
            mammary-derived growth inhibitor expression in cultured mouse
            mammary gland explants
  JOURNAL   In Vitro Cell Dev Biol 28A (9-10), 625-634 (1992)
   PUBMED   1429365
REFERENCE   7  (bases 1 to 680)
  AUTHORS   Bahary,N., Pachter,J.E., Felman,R., Leibel,R.L., Albright,K.,
            Cram,S. and Friedman,J.M.
  TITLE     Molecular mapping of mouse chromosomes 4 and 6: use of a
            flow-sorted Robertsonian chromosome
  JOURNAL   Genomics 13 (3), 761-769 (1992)
   PUBMED   1639403
REFERENCE   8  (bases 1 to 680)
  AUTHORS   Bahary,N., Zorich,G., Pachter,J.E., Leibel,R.L. and Friedman,J.M.
  TITLE     Molecular genetic linkage maps of mouse chromosomes 4 and 6
  JOURNAL   Genomics 11 (1), 33-47 (1991)
   PUBMED   1684952
REFERENCE   9  (bases 1 to 680)
  AUTHORS   Tweedie,S. and Edwards,Y.
  TITLE     cDNA sequence for mouse heart fatty acid binding protein, H-FABP
  JOURNAL   Nucleic Acids Res 17 (11), 4374 (1989)
   PUBMED   2740224
REFERENCE   10 (bases 1 to 680)
  AUTHORS   Heuckeroth,R.O., Birkenmeier,E.H., Levin,M.S. and Gordon,J.I.
  TITLE     Analysis of the tissue-specific expression, developmental
            regulation, and linkage relationships of a rodent gene encoding
            heart fatty acid binding protein
  JOURNAL   J Biol Chem 262 (20), 9709-9717 (1987)
   PUBMED   3036869
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL772297.10.
            
            On Jun 18, 2019 this sequence version replaced NM_010174.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB597130.1, CA490160.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-113               AL772297.10        36888-37000
            114-286             AL772297.10        40441-40613
            287-388             AL772297.10        42104-42205
            389-680             AL772297.10        43322-43613
FEATURES             Location/Qualifiers
     source          1..680
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 63.43 cM"
     gene            1..680
                     /gene="Fabp3"
                     /gene_synonym="Fabph-1; Fabph-4; Fabph1; Fabph4; H-FABP;
                     Mdgi"
                     /note="fatty acid binding protein 3, muscle and heart"
                     /db_xref="GeneID:14077"
                     /db_xref="MGI:MGI:95476"
     exon            1..113
                     /gene="Fabp3"
                     /gene_synonym="Fabph-1; Fabph-4; Fabph1; Fabph4; H-FABP;
                     Mdgi"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..442
                     /gene="Fabp3"
                     /gene_synonym="Fabph-1; Fabph-4; Fabph1; Fabph4; H-FABP;
                     Mdgi"
                     /note="fatty acid-binding protein 3; mammary-derived
                     growth inhibitor; heart-type fatty acid-binding protein;
                     fatty acid binding protein heart 4; fatty acid binding
                     protein heart 1"
                     /codon_start=1
                     /product="fatty acid-binding protein, heart"
                     /protein_id="NP_034304.1"
                     /db_xref="CCDS:CCDS18709.1"
                     /db_xref="GeneID:14077"
                     /db_xref="MGI:MGI:95476"
                     /translation="MADAFVGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIE
                     KNGDTITIKTQSTFKNTEINFQLGIEFDEVTADDRKVKSLVTLDGGKLIHVQKWNGQE
                     TTLTRELVDGKLILTLTHGSVVSTRTYEKEA"
     exon            114..286
                     /gene="Fabp3"
                     /gene_synonym="Fabph-1; Fabph-4; Fabph1; Fabph4; H-FABP;
                     Mdgi"
                     /inference="alignment:Splign:2.1.0"
     exon            287..388
                     /gene="Fabp3"
                     /gene_synonym="Fabph-1; Fabph-4; Fabph1; Fabph4; H-FABP;
                     Mdgi"
                     /inference="alignment:Splign:2.1.0"
     exon            389..680
                     /gene="Fabp3"
                     /gene_synonym="Fabph-1; Fabph-4; Fabph1; Fabph4; H-FABP;
                     Mdgi"
                     /inference="alignment:Splign:2.1.0"
     regulatory      656..661
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fabp3"
                     /gene_synonym="Fabph-1; Fabph-4; Fabph1; Fabph4; H-FABP;
                     Mdgi"
                     /note="hexamer: AATAAA"
     polyA_site      676
                     /gene="Fabp3"
                     /gene_synonym="Fabph-1; Fabph-4; Fabph1; Fabph4; H-FABP;
                     Mdgi"
                     /note="major polyA site"
ORIGIN      
        1 gcggttctca gtgcctgctc gcctcctcac tcatcgcacc atggcggacg cctttgtcgg
       61 tacctggaag ctagtggaca gcaagaattt tgatgactac atgaagtcac tcggtgtggg
      121 ctttgccacc aggcaggtgg ctagcatgac caagcctact accatcatcg agaagaacgg
      181 ggatactatc accataaaga cacaaagtac cttcaagaac acagagatca actttcagct
      241 gggaatagag ttcgacgagg tgacagcaga tgaccggaag gtcaagtcac tggtgacgct
      301 ggacggaggc aaactcatcc atgtgcagaa gtggaacggg caggagacaa cactaactag
      361 ggagctagtt gacgggaaac tcatcctgac tctcactcat ggcagtgtgg tgagcactcg
      421 gacttatgag aaggaggcgt gacctggctg ctccgtcact gaccgcccgc tcctctgcca
      481 actggccacc cctcagctca gcaccatgct gcctcatggt tttcccctct gacattttgt
      541 ataaacattc ttgggttggg atttttctgg agatacgggg catcagcctg gacccagttc
      601 ctactatgta tgtggtttat tttttaaaac tgtatccaaa gggtgctcca aggtcaataa
      661 agcagaacca aggccaccca
//
