LOCUS       NM_177077               5440 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus exocyst complex component 6B (Exoc6b), mRNA.
ACCESSION   NM_177077 XM_001479977 XM_355790 XM_889280 XM_913967 XM_922979
            XM_922986 XM_922994 XM_978347
VERSION     NM_177077.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5440)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5440)
  AUTHORS   Heider,M.R. and Munson,M.
  TITLE     Exorcising the exocyst complex
  JOURNAL   Traffic 13 (7), 898-907 (2012)
   PUBMED   22420621
  REMARK    Review article
REFERENCE   3  (bases 1 to 5440)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (bases 1 to 5440)
  AUTHORS   Nishiguchi,S., Sakuma,R., Nomura,M., Zou,Z., Jearanaisilavong,J.,
            Joh,T., Yasunaga,T. and Shimada,K.
  TITLE     A catalogue of genes in mouse embryonal carcinoma F9 cells
            identified with expressed sequence tags
  JOURNAL   J Biochem 119 (4), 749-767 (1996)
   PUBMED   8743579
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC153373.4, AC155289.11, AC155331.5, AC153994.8 and AC153606.3.
            
            On or before Apr 5, 2009 this sequence version replaced
            XM_922979.2, XM_913967.2, XM_922986.2, XM_922994.2, XM_001479977.1,
            XM_355790.4, XM_889280.2, XM_978347.1, NM_177077.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219380.34009.1, BC144781.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-218               AC153373.4         101490-101707
            219-384             AC153373.4         159520-159685
            385-432             AC153373.4         165967-166014
            433-523             AC153373.4         167718-167808
            524-569             AC153373.4         167910-167955
            570-774             AC153373.4         181474-181678
            775-951             AC155289.11        57568-57744         c
            952-1020            AC155289.11        39972-40040         c
            1021-1104           AC155331.5         25253-25336
            1105-1151           AC155331.5         25752-25798
            1152-1272           AC155331.5         27463-27583
            1273-1344           AC155331.5         30425-30496
            1345-1442           AC155331.5         31173-31270
            1443-1548           AC155331.5         32289-32394
            1549-1658           AC155331.5         34011-34120
            1659-1770           AC155331.5         37094-37205
            1771-1905           AC155331.5         41828-41962
            1906-2085           AC155331.5         50751-50930
            2086-2227           AC155331.5         94589-94730
            2228-2301           AC153994.8         21535-21608
            2302-2414           AC153606.3         202593-202705       c
            2415-5440           AC153606.3         195954-198979       c
FEATURES             Location/Qualifiers
     source          1..5440
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 36.55 cM"
     gene            1..5440
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /note="exocyst complex component 6B"
                     /db_xref="GeneID:75914"
                     /db_xref="MGI:MGI:1923164"
     exon            1..218
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     CDS             109..2541
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /note="SEC15-like 2; SEC15-like protein 2; exocyst complex
                     component Sec15B"
                     /codon_start=1
                     /product="exocyst complex component 6B"
                     /protein_id="NP_796051.2"
                     /db_xref="CCDS:CCDS51824.1"
                     /db_xref="GeneID:75914"
                     /db_xref="MGI:MGI:1923164"
                     /translation="MERAKMAEESLETAAEHERILREIESTDTACIGPTLRSVYDGEE
                     HGRFMEKLETRIRNHDREIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKL
                     QHEGKELVIAMEELKQCRLQQRNISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALK
                     TLEHLEHTYLPQVSHYRFCKVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIGET
                     AMKQAQQQRNLDNIVLQQPRIGSKRKSKKDVYTIFDAEVESTSPKSEQDSGILDVEDE
                     EDDEEVPGAQDLVDFSPVYRCLHIYSVLGARETFENYYRKQRRKQARLVLQPPSNMHE
                     TLDGYRKYFNQIVGFFVVEDHILHTTQGLVNRAYIDELWEMALSKTIAALRTHSSYCS
                     DPNLVLDLKNLIVLFADTLQVYGFPVNQLFDMLLEIRDQYSETLLKKWAGVFRNILDS
                     DNYSPIPVTSEETYKKVVGQFPFQDIELEKQPFPKKFPFSEFVPKVYNQIKEFIYACL
                     KFSEDLHLSSTEVDDMIRKSTNLLLTRTLSNSLQNVIKRKNIGLTELVQIIINTTHLE
                     KSCKYLEEFITNITNVLPETVHTTKLYGTTTFKDARHAAEEEIYTNLNQKIDQFLQLA
                     DYDWMTGDLDNKASDYLVDLIAFLRSTFAVFTHLPGKVAQTACMSACKHLATSLMQLL
                     LEAEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQEDTLQLAFIDLRQLLDLFIQWD
                     WSTYLADYGQPNCKYLRVNPVTALTLLEKMKDTSRKNNMFAQFRKNERDKQKLIDTVA
                     KQLRGLISSHHS"
     exon            219..384
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            385..432
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            433..523
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            524..569
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            570..774
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            775..951
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1020
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1104
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1151
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1152..1272
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1344
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1442
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1443..1548
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1549..1658
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1659..1770
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1771..1905
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1906..2085
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            2086..2227
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            2228..2301
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            2302..2414
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     exon            2415..5440
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5405..5410
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /note="hexamer: ATTAAA"
     polyA_site      5440
                     /gene="Exoc6b"
                     /gene_synonym="4930569O18Rik; G430127E12Rik; mKIAA0919;
                     Sec15b; Sec15l2"
                     /note="major polyA site"
ORIGIN      
        1 atccgagggc ggggtcgcgc tgcggggtgc tggcccagcg gccgcagatc ctgggcagag
       61 ggatcgtggg gtactcgctg agagagggcc gcgcggcagc gccctgcgat ggagcgggcg
      121 aagatggcgg aggagagcct ggagacggcg gcggagcacg agcggatcct gagggagatc
      181 gagagcacag acacggcctg catcgggccc acgctcaggt ctgtctatga tggtgaggaa
      241 catggacgat tcatggagaa gctagaaact cgtatccgca atcatgacag agaaatcgag
      301 aaaatgtgca actttcacta ccagggcttt gtggactcta ttactgagct gctgaaagta
      361 cgaggagaag cccagaaact caaaaaccag gtgacggaca ctaataggaa actgcagcac
      421 gagggcaagg aactggtaat agcaatggag gagctgaagc agtgtcgact acaacagaga
      481 aatatttctg ccactgtcga taagctaatg ctgtgtcttc cagtcctaga gatgtacagc
      541 aaactgaggg accagatgaa aaccaaaagg cattatcctg cactgaagac actggagcat
      601 ctggaacaca cctatctgcc tcaagtgagc cactatcgat tctgtaaggt gatggtggac
      661 aacatcccca agcttcggga ggaaataaaa gatgtttcta tgtctgatct caaagacttt
      721 ctggagagca tccgcaagca ttcagacaaa attggagaga ctgccatgaa gcaagcccaa
      781 cagcaaagaa acctggataa cattgtcttg caacagccta gaataggtag caaaaggaaa
      841 tctaagaaag atgtttatac aatctttgat gcagaggtgg agagcacaag tccaaagtcg
      901 gaacaggatt cgggaattct ggatgtggaa gacgaggaag atgatgaaga ggtacctggg
      961 gctcaagact tggtggattt ctctcctgtg tatcggtgtc tacacatata ttctgtcctg
     1021 ggtgcccgtg aaacatttga gaattactac cgaaaacaga ggcgaaaaca ggctcgtttg
     1081 gtactccagc ctccgtctaa tatgcatgaa actttagatg gctacaggaa gtatttcaat
     1141 caaattgtag gcttttttgt ggttgaagat cacattttgc atacaaccca gggcttagtg
     1201 aatagagcct acattgatga actgtgggaa atggcccttt caaagaccat cgcagcattg
     1261 cgtacccact cgtcctactg ttctgatcca aacctcgtgt tagatttgaa gaacctcatt
     1321 gtactctttg cggacacact tcaggtgtat ggttttcctg tgaatcagct ttttgatatg
     1381 ttgttagaaa tcagagacca gtacagcgag actctattga agaagtgggc aggggttttc
     1441 agaaatatac ttgattctga caactacagt cccataccag taacaagtga agagacatat
     1501 aaaaaagtcg taggacaatt cccgtttcaa gatatagaac tggaaaagca gccatttccc
     1561 aaaaagtttc ctttctctga atttgtgcca aaagtttaca accagattaa agaatttatc
     1621 tacgcctgcc tgaagttttc agaagatctt catctaagct ccactgaagt cgatgacatg
     1681 atccgtaagt ctacaaactt gttgctgacc aggactctga gcaactctct gcagaacgtc
     1741 attaagagga agaacattgg ccttactgag cttgtccaga ttatcatcaa tacaacacac
     1801 ttggagaagt cctgtaaata cctggaggaa ttcatcacca atatcactaa tgtccttcca
     1861 gagacggtcc ataccaccaa gctttatggt accacaactt tcaaggatgc tagacatgca
     1921 gctgaagaag agatatatac aaacctaaat cagaagattg accagtttct gcagctggct
     1981 gactacgact ggatgactgg agacctagac aacaaagcca gtgattacct ggtagacctc
     2041 attgccttcc tccggagcac ctttgctgtg ttcacacacc ttcctggaaa ggtggctcag
     2101 acagcatgta tgtcagcttg caagcattta gccacatcct tgatgcaact tttgctagaa
     2161 gcggaagtac ggcagctcac tttgggagca ttgcagcagt tcaacctgga tgtcagagaa
     2221 tgtgaacagt ttgccagatc cggcccggtg cctgggttcc aggaggacac gctgcagttg
     2281 gccttcatcg acttgagaca actattggac ctctttattc agtgggattg gtccacatac
     2341 cttgccgact atggacagcc caactgcaag tatctccggg tgaaccctgt gacagctctg
     2401 accctgcttg agaagatgaa agatactagc cgcaagaata acatgtttgc acagttccgg
     2461 aaaaatgagc gagataagca gaaattgatt gacaccgtgg ccaagcagct ccgaggactc
     2521 atcagcagcc accactcctg aatgttggcc ttgggcccac agagggccac ttgctgtagc
     2581 cagtggtcca ggatctcccc tgggctggcc ctgcatttgt gcattcttcc tcaaagagag
     2641 catatgtatt tttttattaa cccctgtaca gttttcacat aacctttccc tatagtaaga
     2701 gaggcacaag agtaagcaag aaccagggct tagaggaagt tactgctaca ctttcctggg
     2761 aaagctacac tgtcagtgcc aacatggtga gccgcatcca gtgctccacg aatttagtgg
     2821 gtacctagca ctgggagttg agatgagaaa gtaaaaggat aataatatat atcctgtttg
     2881 ctctcaagta tttgcttaag tacataagta gagcctggca gacatgacta tgtagtatgc
     2941 caaagccagc ctcagtttag gatatctatc tgccttgctg gttgaattat tggctcatga
     3001 gagtgtggca tgtggcaaga tgacagtttc actctggtcc catagcttgc agtttcatta
     3061 gtttaggtct ggctgagcct tgtggggaga agggtagtta gctgaaaagg aagttgcccc
     3121 actaggtgag ttgtttttct gaatcttaaa aagccaagtt gggtcaggac tccagtcccc
     3181 atgccattca tctctgtctc ttcttttatg accataactc ttggttcaga acataaatca
     3241 gcaattctta aggtccctga gagtctcaca ctcaattcca gcagcatctc taaatgccca
     3301 gattccctga agtctgaaag tagcctgggt gccctcacca tgggtagagc ctcatgatgt
     3361 gtgagattgc atattcctgt cttgatgaca gccttacagc taccatcttt caagaaaacg
     3421 tcccaagctc tacacccttg ggcacaacca ccataggact agatgtttct gagaatggat
     3481 ctatcaccat gatgtagaca gggtcaactg tagctaatgg attattgcct ctggcccagc
     3541 tgtcatcaac aaaataacat cacagagaca aggcttgtct tgttcaagcc caaggctccc
     3601 atcttctgag ctgtccctta gcctcaccta agagtgcttt ctcgaagtca catctctgtt
     3661 ttctggagtg tgggctaact atagactcct gagatcctgt gaaggcgttc ctgtgaagtt
     3721 ggccagaggg actttgcact gagacacttg tagaagctgt tagcctgact gctgctgaga
     3781 gtttaattgc attgtggaac actgaccaag atgccacaaa agtgtttcca gctccagtga
     3841 ggagcagaga gactggtcaa gcaatcactt attacgtttg tcagctattg tgtcattctg
     3901 gaacagctgt acttccatat ctcttagccc accacagcct acgtcatctt gaacacgcct
     3961 cacccttgcc atagcaatct caaacaccag caagaaaagt acaccacaca gaggtacagc
     4021 tttctacaac tggagagaac aagctaccca ggtgttctgc ataagccttc aagtctcatc
     4081 atcaggctac ataatggccc agaggttcag gaagagtcac agaagaatac acaaaactta
     4141 ctagccagca gagagcccag gcctgtggaa gagaagacaa ggagatctct cgaagccctc
     4201 agtctgtgac cagtgagaag tgactccaca aacctgactg actgagaagg aaggaaaggc
     4261 cctttcttca ccagggcttg tcagccttca gtgtagagag tgggctgtca caacatttgt
     4321 cctttgggga cacttttaat cactccatct tgctgcctgt ctagttgcca cctctgtccc
     4381 aaaggaactg acatggatgg aatgaaaacc atgtgtagga ccagggccac tctaccttcc
     4441 tcaccagagt cctgctgacg gggactctca ttcagtcaca gagtgtgagg atggccgctt
     4501 gcctttgccc agctctgcgt ctgctgtgct gttctctgac aaagcagctt gctgcctctg
     4561 agccgggaaa gcggggtcca cagtgtgagg gggctatgaa ttgatgaggt gggactttgt
     4621 tttttcattt tgtccttagg cctaaagctg agctggcctt gaagacttga gcacagaatg
     4681 tgtgctggta ggcctcagac tctgacctta cctcagatgc ctacagacca tattccttca
     4741 gtttcaggtg gggtgagacg ctgctgcctg gaagtctgtg gccttctaac cagatccata
     4801 gccctgtaga cagtatggtt tgtgagcctt ggttaagcag gggctcactt atttttttat
     4861 cattcatgag ggaaaaacat aacaaaacaa aacaaaactc tcagtaccag gtaacactgg
     4921 tatgggtgga gaagagcagg acctgcatac aggagcccag aatcccagtt aacaaaagca
     4981 gtatctccca gtgactctat catgcatcag gcctgacagt ccgtccagct ctatggcacc
     5041 cagctcagca ggtcccaagc ccaagggtgg cagtggccag ttttctcctt agacctctga
     5101 gtgcaggctt gggtggcttc accacgcctc cttcagcctg cttttgctgt gcccctccct
     5161 ccacccctct gttccttctc tcctattcac ttgcatttgc gtcactcctc cctgacatgt
     5221 tggaaattgc cttttcgttt tgcgcagttc cacatttgtg ggagaaaagc agtgagatcc
     5281 atctgaacct ccaaaaggaa ccttctcctc tcatgctctg ctgcaggctg ctgcagaagg
     5341 gggctcctct gtggaaagag catgagtaac ccactcccct gtgcaccttc ctcttttaac
     5401 tgctattaaa cgagagccta catacccatt gcaaaagcca
//
