LOCUS       NP_780562                804 aa            linear   ROD 28-APR-2025
DEFINITION  exocyst complex component 6 [Mus musculus].
ACCESSION   NP_780562 XP_920018
VERSION     NP_780562.2
DBSOURCE    REFSEQ: accession NM_175353.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 804)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 804)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 804)
  AUTHORS   Mirciov,C.S., Wilkins,S.J., Dunn,L.A., Anderson,G.J. and
            Frazer,D.M.
  TITLE     Characterization of Putative Erythroid Regulators of Hepcidin in
            Mouse Models of Anemia
  JOURNAL   PLoS One 12 (1), e0171054 (2017)
   PUBMED   28135344
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 804)
  AUTHORS   Sano,H., Peck,G.R., Blachon,S. and Lienhard,G.E.
  TITLE     A potential link between insulin signaling and GLUT4 translocation:
            Association of Rab10-GTP with the exocyst subunit Exoc6/6b
  JOURNAL   Biochem Biophys Res Commun 465 (3), 601-605 (2015)
   PUBMED   26299925
  REMARK    GeneRIF: These results suggest that the association of Rab10-GTP
            with Exoc6/6b is a molecular link between insulin signaling and the
            exocytic machinery in GLUT4 translocation.
REFERENCE   5  (residues 1 to 804)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   6  (residues 1 to 804)
  AUTHORS   Bloom,M.L., Simon-Stoos,K.L. and Mabon,M.E.
  TITLE     The hemoglobin-deficit mutation is located on mouse chromosome 19
  JOURNAL   Mamm Genome 9 (8), 666-667 (1998)
   PUBMED   9680389
REFERENCE   7  (residues 1 to 804)
  AUTHORS   Bloom,M.L. and Simon-Stoos,K.L.
  TITLE     The hemoglobin-deficit mouse: analysis of phenotype and
            hematopoiesis in the transplant model
  JOURNAL   Blood 90 (5), 2062-2067 (1997)
   PUBMED   9292544
REFERENCE   8  (residues 1 to 804)
  AUTHORS   Bannerman,R.M., Garrick,L.M., Rusnak-Smalley,P., Hoke,J.E. and
            Edwards,J.A.
  TITLE     Hemoglobin deficit: an inherited hypochromic anemia in the mouse
  JOURNAL   Proc Soc Exp Biol Med 182 (1), 52-57 (1986)
   PUBMED   3960859
REFERENCE   9  (residues 1 to 804)
  AUTHORS   Bannerman,R.M., Edwards,J.A. and Pinkerton,P.H.
  TITLE     Hereditary disorders of the red cell in animals
  JOURNAL   Prog Hematol 8, 131-179 (1973)
   PUBMED   4596202
REFERENCE   10 (residues 1 to 804)
  AUTHORS   Scheufler,H.
  TITLE     [An additional house mouse mutant with anemia (hemoglobin
            deficiency)]
  JOURNAL   Z Versuchstierkd 11 (5), 348-353 (1969)
   PUBMED   5405927
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY100185.1, AK082881.1, CD806857.1, AK076455.1 and AC110212.12.
            
            On or before Dec 7, 2005 this sequence version replaced
            XP_920018.1, NP_780562.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK151524.1, AK151838.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..804
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 32.32 cM"
     Protein         1..804
                     /product="exocyst complex component 6"
                     /note="SEC15-like 1; SEC15 homolog; SEC15-like protein 1;
                     exocyst complex component Sec15A"
                     /calculated_mol_wt=93156
     Region          456..762
                     /region_name="Sec15"
                     /note="Exocyst complex subunit Sec15-like; pfam04091"
                     /db_xref="CDD:461169"
     CDS             1..804
                     /gene="Exoc6"
                     /gene_synonym="4833405E05Rik; C430002C19; hbd; msec15;
                     Sec15; Sec15l1"
                     /coded_by="NM_175353.2:48..2462"
                     /db_xref="CCDS:CCDS29779.1"
                     /db_xref="GeneID:107371"
                     /db_xref="MGI:MGI:1351611"
ORIGIN      
        1 maescealgt vpeherilqe iestdtacvg ptlrsvyddq pnahkkfmek ldacirnhdk
       61 eiekmcnfhh qgfvdaitel lkvradaekl kvqvtdtnrr fqdagkevii qtediircri
      121 qqrnittvve klqlclpvle mysklkeqms mkryysalkt meqlenvyfp rvsqyrfcql
      181 mmetlpklre dikdismsdl kdflesirkh sdkigeaamk qaqqqksfsv alqkqnnmrf
      241 gknmhvnndr ileeksdvip khaleeeaen deevltvqdl vdfspvyrcl hiysalgdee
      301 tfenyyrkqr kkqarlvlqp qssvhetvdg yrryftqivg ffvvedhilh vtqglvtrvy
      361 teelwnmals kiiavlrahs syctdpdlvl elknlivifa dtlqgygfpv nrlfdllfei
      421 rdqynetllk kwagifrdif eednyspipi gseeeykvvi srfpfqdpdl ekqsfpkkfp
      481 msqsvpliyi qvkefiyasl kfseslhrss teiddmlrks tnllltrils scllnlirkp
      541 higltelvqi iintthleqa ckyledfitn itnisqetvh ttrlyglstf kdarhaaege
      601 iytklnqkid efvqladydw tmaesdgras gylmdlinfl rsifqvfthl pgkvaqtacm
      661 sacqhlstsl mqmlldselk qismgavqqf nldviqcelf assepvpgfq gdtlqlafid
      721 lrqlldlfmv wdwstylady gqpaskylrv nphaaltlle kmkdtskknn ifaqfrkndr
      781 drqklietvv rqlrglvtgm sqht
//
