LOCUS       NM_001289487            3525 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus exocyst complex component 3-like 4 (Exoc3l4),
            transcript variant 1, mRNA.
ACCESSION   NM_001289487 XM_006516288
VERSION     NM_001289487.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3525)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3525)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122190.4, BY235568.1, BC075664.1, AK004674.1, BM247872.2,
            BQ032492.1 and BY701311.1.
            
            On Jan 23, 2014 this sequence version replaced XM_006516288.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript. Variants 1, 2, 3 and 4 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-189               AC122190.4         87321-87509         c
            190-515             BY235568.1         1-326
            516-1302            BC075664.1         252-1038
            1303-1303           AK004674.1         1055-1055
            1304-2570           BC075664.1         1040-2306
            2571-2571           BM247872.2         459-459             c
            2572-3028           BC075664.1         2308-2764
            3029-3523           BQ032492.1         18-512              c
            3524-3525           BY701311.1         382-383
FEATURES             Location/Qualifiers
     source          1..3525
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 60.98 cM"
     gene            1..3525
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /note="exocyst complex component 3-like 4"
                     /db_xref="GeneID:74190"
                     /db_xref="MGI:MGI:1921363"
     exon            1..325
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            326..430
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            431..515
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            516..931
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             532..2697
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /note="SEC6-like protein C14orf73 homolog"
                     /codon_start=1
                     /product="exocyst complex component 3-like protein 4"
                     /protein_id="NP_001276416.1"
                     /db_xref="CCDS:CCDS26177.1"
                     /db_xref="GeneID:74190"
                     /db_xref="MGI:MGI:1921363"
                     /translation="MPLPQTGAPGPEVKSPREPRKSQTLPVTTWKSNSMKEQSVHHGG
                     SLRPSLGMLKQTLFRTSLRTSTHKPKEDPGLFRRSSRFLFRSLRRAIDEGLTAGHPQG
                     PAVPEKPSKVTDGVSRQAATGTEAEDLEPQAESKSVADLITERQLVKAFEQLRYLETQ
                     LVADKTSRTFTQDPTAYARRAMDLCLHYDGMAAEIGAIVREALSSEGVDRDALAELAQ
                     VVHLEEEAHQTSQAEGDFLSTPRHWRMHWEDAVRLSAQERVQQAGAKVIPGAAEGSSD
                     LAQLLAELGGVVRHDLQKVRLEMQPAYEATDFPVWETYLRAFHSAVAQRLQELARDAR
                     GCEQLYVLLDWAANVYGSPDFLGAPDLALPTEPLPPLLEPALWARLESDYTSFLETKI
                     TSCFDSILQLEQNRWEADEDREVLQGLYHAPLSIDVHMLVAEHVKAAGAISAELEATT
                     LQICARALCLFVPRFEKAFLASKAVSEWYLGAYINACVELRTSLLARFPGTIKELEKP
                     LVAATNSFQKHLLQIVQQDMQPLFKVLYTKSWLTQDTLRPLMDKVVDFAHHLEHVTPP
                     LAQETLQEVHRFVVREYLGQVLRPHERFSGQDRLKGSNKMNLDAQAISNTFQGLGSEA
                     KWLDQAILSVAEILGETYKDDIRRHLETLIRSYPDIRRDHILAILALRRLGRRRNQNL
                     LQHTQDLLRAAHETRLPSHHVLFEEIEVPTSVDVLITCI"
     exon            932..1586
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1587..1698
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1699..1821
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1822..1922
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1923..2003
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2004..2118
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2119..2238
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2239..2391
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2392..2513
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2514..3525
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3004..3009
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /note="hexamer: AATAAA"
     regulatory      3015..3020
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3028
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /note="major polyA site"
     polyA_site      3046
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
     regulatory      3505..3510
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3523
                     /gene="Exoc3l4"
                     /gene_synonym="1200009I06Rik; 1600013K19Rik"
ORIGIN      
        1 cttagggccc tccctagcct cccctcccca gtctctccct gtcaagctcc gatcaggctc
       61 aggcaagctc cgggactgtg gctgatcaaa ggttagagtg gttgtctctg gaatgaaagg
      121 ggtggaactt ttctgaaagc gaaagtatgg ggtccgagta gagagtgggt cagggcggtc
      181 ctgtggctgg gaagtcccag ctgttggtcc accagttggg ctgtgctggc agccatctct
      241 ctcctggacc tggtctcagg atcctgcttg gctggcttgc ttaggacctc tgctgcctgg
      301 gtgcagttgt ctgcgtgcct atcaggaaag gactcagctt gcagggaagg tttcaaggca
      361 cggacgccac aacctgctgg cagtggttgc ccctggggct ttgaaggaca ggggatagcc
      421 tggtcctacg atcccaggct ccggccccag aagggaaagc ctcttaagaa gcttccggtt
      481 tgagcagcca agatcctgcc tttcgagctg aagggctctc ctgctgccaa gatgcctttg
      541 cctcagacag gggcccctgg gccagaggta aaaagcccca gggagcctag gaagtcacag
      601 accctccctg tgaccacctg gaagtccaac agtatgaaag agcagagcgt gcaccacggg
      661 ggcagcttga gacccagcct gggcatgctg aagcagaccc tcttccggac cagcctgaga
      721 acttcaaccc acaagcccaa ggaggaccca ggcctgttca ggcgcagctc ccgtttcctg
      781 ttcaggtcct tgagacgggc catagatgaa ggcttaactg ctgggcatcc ccaaggccct
      841 gcggtaccag agaagccctc caaagtcaca gatggcgtca gcaggcaggc agccactggg
      901 acagaggctg aggatctgga accccaggca gaaagtaaat ccgtggcaga cctcatcact
      961 gagcggcagc tagtgaaggc ctttgaacaa ttgcggtacc tggagacgca gctggtagcc
     1021 gacaaaactt cccgcacctt tacacaggac cccaccgcct atgctcggcg cgctatggac
     1081 ctttgtctac attacgacgg aatggctgcg gagatcggag ccattgtgcg cgaggcgctg
     1141 agttccgaag gcgtggatcg agacgctcta gcggaactgg cccaagtggt acacttggaa
     1201 gaggaggccc atcagacctc ccaggccgag ggtgatttct tgagtacacc ccgccactgg
     1261 cgtatgcatt gggaggacgc ggtgcgtctc agcgctcagg agcgcgtaca gcaggcaggc
     1321 gcaaaagtca tccccggggc tgcggagggc tcatccgacc tagcccagct tctggctgag
     1381 ctcggcggtg tggttcgcca cgacctgcag aaggtgcgct tagagatgca gcccgcttac
     1441 gaagccaccg acttcccagt gtgggagacc tacttgcgtg ccttccacag cgctgtggcc
     1501 cagcgtctac aggagctggc gcgagacgcc cgcggctgtg agcagctcta tgtgctgtta
     1561 gactgggccg ctaatgtcta tggcagtcct gacttcctgg gcgccccaga cttggcgctg
     1621 cccaccgagc cgctgccccc acttctagag cctgctctgt gggctcgact ggaaagtgac
     1681 tacactagct tcctagagac caagatcaca agctgttttg acagcatctt gcagctggaa
     1741 cagaatcgct gggaagccga cgaggaccgg gaagtactgc agggcctcta ccacgcgccc
     1801 ctgtccatcg atgtgcacat gctggtagct gagcatgtga aggcagctgg cgctatctcc
     1861 gcggagctgg aggccactac cctgcagatc tgcgcgcgtg cgctctgtct ctttgtgccc
     1921 aggtttgaaa aggcttttct ggcgtcgaag gcagtgagcg aatggtacct gggtgcttac
     1981 attaacgcct gcgtggagct gagaaccagt cttctggcca ggttcccagg aaccataaag
     2041 gaactggaga aacccctagt ggctgccacc aatagcttcc agaaacattt gctccagatt
     2101 gtacagcaag acatgcagcc tctatttaag gtgctatata ccaagagctg gctcacacag
     2161 gacacacttc gtcccctcat ggacaaagtg gtggactttg cacatcatct tgagcatgtg
     2221 accccaccac tggcacagga gacactgcag gaggtgcacc gttttgtggt ccgcgaatac
     2281 ctggggcagg tgctgaggcc ccacgagagg ttcagtggcc aggatcgact gaagggctct
     2341 aataagatga acctggatgc ccaggccatt agcaacacct tccagggctt gggctctgaa
     2401 gccaagtggc tggaccaagc catcctgtct gtggctgaga tcctgggcga gacatacaaa
     2461 gacgacatcc ggcggcacct ggaaacactt atacggagct acccggacat caggcgagac
     2521 cacattctgg ccattctggc actacgcaga ctcggccgcc gccggaacca gaatctcttg
     2581 caacacaccc aagacttgct gagggctgcc cacgagacca ggctcccctc acaccacgtg
     2641 ctcttcgagg agatcgaagt gcccacctct gtggacgtgc taatcacctg catctagggc
     2701 tgaagggcga gcaggagcct cgttggccga ggatctgtca ccctctccat gactgacccc
     2761 aagttgggag cccagtgagt cactctggcc ctacccccag cactgaagcc tggggacatg
     2821 gaatttttgg tctcagctgc ctggctgctc agccagagga gccaggagat gaggcattcc
     2881 gggcatttgt gggggagtct tttggggctg cggagtctcc tttcaggact tcaggccagg
     2941 gaaggcttcc ctttctaact gctcagcaca tccacactgt agtgcgaagc tgaggattct
     3001 aaaaataaat gtgaattaaa atagtgtaca aggttgggca agctaagctg gttgggagag
     3061 gtgatgctgg attgaatgta tgggaggacc gagccagtcc tgagctggaa aagcccctgc
     3121 ctgcctcagc agatcaaaac aggagccttg gctctccctt caaaggttgt gctcccagca
     3181 cccacagggc gataaacaac cgtcctcaac tccagttcca gaggaccaaa cgccctctct
     3241 ggcctctgtg agtgtgagct tgtgctgaac acagacatgc aggcaggcaa gacacgtgtg
     3301 cataaaggaa aactaaatac attttaaaag caacaacaaa gcaaaggcag accccacacc
     3361 ctgggtccct agcctcagac accacgttgg tcttgcccag aaggggtaga cagccctcag
     3421 cctcttgcta ggcacctgag ccctcgtgag caccggttct gcagcttgca gtattctagt
     3481 ttcatgtagg agggactctc aagcaataaa atttgccagg tcact
//
