LOCUS       NM_028457               1990 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus exonuclease 5 (Exo5), transcript variant 1, mRNA.
ACCESSION   NM_028457
VERSION     NM_028457.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1990)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1990)
  AUTHORS   Zaman,Q., Khan,R., Hameed,U., Shah,W., Waqas,A., Zubair,M., Dil,S.,
            Zafar,T., Ali,A., Unar,A. and Shi,Q.
  TITLE     Exonuclease 5 is dispensable for meiotic progression and male
            fertility in mouse
  JOURNAL   Gene 769, 145254 (2021)
   PUBMED   33164760
REFERENCE   3  (bases 1 to 1990)
  AUTHORS   Sparks,J.L., Kumar,R., Singh,M., Wold,M.S., Pandita,T.K. and
            Burgers,P.M.
  TITLE     Human exonuclease 5 is a novel sliding exonuclease required for
            genome stability
  JOURNAL   J Biol Chem 287 (51), 42773-42783 (2012)
   PUBMED   23095756
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CA548348.1 and AK014134.1.
            
            On May 9, 2009 this sequence version replaced NM_028457.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK014134.1, BC023360.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-494               CA548348.1         13-506
            495-1990            AK014134.1         493-1988
FEATURES             Location/Qualifiers
     source          1..1990
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 56.65 cM"
     gene            1..1990
                     /gene="Exo5"
                     /gene_synonym="3110037I16Rik; Dem1; Exo V; mExo5"
                     /note="exonuclease 5"
                     /db_xref="GeneID:73172"
                     /db_xref="MGI:MGI:1920422"
     exon            1..495
                     /gene="Exo5"
                     /gene_synonym="3110037I16Rik; Dem1; Exo V; mExo5"
                     /inference="alignment:Splign:2.1.0"
     exon            496..1990
                     /gene="Exo5"
                     /gene_synonym="3110037I16Rik; Dem1; Exo V; mExo5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacaggggtg aagagctaag gggctgcccc tttcaggcac gcccctcatt cgggtttttg
       61 ttctgtgcat tttgggcccg cgattgagtc tttgcgcttg ggcacaccag ggggactggg
      121 gctgggggct gagtggaaag cacacgcctg cctgcgtgga aggcctgtaa cgagtcagga
      181 cgcagaggat gaaggcagca gcaggcagcc ggaagccatc agcaaggcag ggcctccgac
      241 ctcaggctgc ggctgggaac ctggagagca gaacttaccg cctggagacc ttacccttgg
      301 agaggccagt gttaggagga tttatgacac gcagctgccc tagcagtgtg actcaagtgg
      361 aaacaccata atgtgaagga gtggtcaggt gaagagaaca gaagtccaca ttccatcata
      421 gcaaggtgcc tccccatctc ccctcgtttt aatacatgct cttccctgtg aggagggaaa
      481 tcaactaagg cccaggtccc tatttgttca atctagggct gtaccatggc tgagactggg
      541 gaagaggaga cagcatcagc agaagcctca gggttttcag acttgagtga ctcagagtta
      601 gttgaatttc tggatctgga agaagccaaa gaatcggctg tttcacttag caagcctggc
      661 ccttctgctg aactccctgg gaaggatgac aaaccagtaa gcttgcagaa ctggaaaggg
      721 ggattggatg tcttgtcacc catggagaga ttccacctga aatatttata tgtcactgac
      781 ctgtgcactc agaactggtg tgagttgcag atggtgtacg ggaaggagct tcctggttcg
      841 ttgacacctg agaaagcagc tgttttggac actggtgcta gcatccacct agcaaaagaa
      901 ctagaacttc atgaccttgt gacagtcccc atcgccacaa aagaagatgc ttgggcagtt
      961 aagtttctga acatactagc aatgattcct gccctacagt cggaagggcg cgtcagagag
     1021 tttccagtgt ttggggaggt ggagggaata tttcttgttg gagtcattga tgagttgcac
     1081 tacacatcca agggggaact agagctggct gaactcaaga cacgaaggcg ccccgtgctc
     1141 cccctgccag ctcagaaaaa gaaagactat tttcaagtta gcctatacaa atatatcttt
     1201 gatgccatgg tacaagggaa agtgactcct gctagcctaa tccaccacac taaattgtgt
     1261 ctagacaagc cactgggacc ttctgtgctg aggcatgcca gacaaggagg cgtgtctgta
     1321 aaatctttgg gtgaccttat ggaactggtt ttcttgtctc ttacactgtc tgatctccca
     1381 gctattgata ccctaaaact tgagtatatc catcaagaga ctgccactat actgggcaca
     1441 gagattgtag cctttgaaga gaaggaagtg aaaagcaagg tgcagcatta cgtggcctac
     1501 tggatgggcc accgagatcc tcaaggcgtt gatgtggagg aggcatggaa gtgccggacc
     1561 tgtgactatg tggacatctg cgagtggagg aggggcagtg gagtgctcag ctcatcgtgg
     1621 gagcccaaag ccaagaagtt taaatgaatg aaggtacact ttcagaaatg ttgatcgttt
     1681 ctgttcttaa tatacccatg taagaggacc agtctctcag cttggctctc gtggacagtg
     1741 ttttttatgt ttacaatctt gaataacatt ccatcccagg gccaaagatc aagaatgtgg
     1801 agagatgtgg tgttagagtg accttggagc tttcaggtaa actgcaaaga agacagatat
     1861 acatcagtgc agcaaaggta tccctcacta atcactgttg gctcaagaaa attctttgga
     1921 ttctgataaa tctttacttt tttcttgata atttttttac attttttaca ataaaaatga
     1981 aatgctgtct
//
