LOCUS       NM_001346730            3976 bp    mRNA    linear   ROD 23-AUG-2023
DEFINITION  Mus musculus ecotropic viral integration site 5 like (Evi5l),
            transcript variant 2, mRNA.
ACCESSION   NM_001346730 XM_006508748
VERSION     NM_001346730.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3976)
  AUTHORS   Bedogni F and Hevner RF.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3976)
  AUTHORS   Chai G, Webb A, Li C, Antaki D, Lee S, Breuss MW, Lang N, Stanley
            V, Anzenberg P, Yang X, Marshall T, Gaffney P, Wierenga KJ, Chung
            BH, Tsang MH, Pais LS, Lovgren AK, VanNoy GE, Rehm HL, Mirzaa G,
            Leon E, Diaz J, Neumann A, Kalverda AP, Manfield IW, Parry DA,
            Logan CV, Johnson CA, Bonthron DT, Valleley EMA, Issa MY,
            Abdel-Ghafar SF, Abdel-Hamid MS, Jennings P, Zaki MS, Sheridan E
            and Gleeson JG.
  TITLE     Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause
            Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly
  JOURNAL   Neuron 109 (2), 241-256 (2021)
   PUBMED   33220177
REFERENCE   3  (bases 1 to 3976)
  AUTHORS   Anderson AE, Taniguchi K, Hao Y, Melhuish TA, Shah A, Turner SD,
            Sutherland AE and Wotton D.
  TITLE     Tgif1 and Tgif2 Repress Expression of the RabGAP Evi5l
  JOURNAL   Mol Cell Biol 37 (5), e00527-16 (2017)
   PUBMED   27956704
  REMARK    GeneRIF: Tgifs regulate ciliogenesis and suggests that Evi5l
            mediates at least part of this effect.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3976)
  AUTHORS   Itoh T, Satoh M, Kanno E and Fukuda M.
  TITLE     Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16)
            domain-containing proteins based on their Rab-binding activity
  JOURNAL   Genes Cells 11 (9), 1023-1037 (2006)
   PUBMED   16923123
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC123029.3.
            
            On Feb 27, 2019 this sequence version replaced NM_001346730.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7974084.15344.1,
                                           SRR1660819.159292.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-197               AC123029.3         43470-43666
            198-380             AC123029.3         60391-60573
            381-570             AC123029.3         62864-63053
            571-795             AC123029.3         64144-64368
            796-870             AC123029.3         64479-64553
            871-996             AC123029.3         65190-65315
            997-1140            AC123029.3         68140-68283
            1141-1230           AC123029.3         68488-68577
            1231-1328           AC123029.3         70023-70120
            1329-1389           AC123029.3         70209-70269
            1390-1443           AC123029.3         77771-77824
            1444-1476           AC123029.3         78837-78869
            1477-1617           AC123029.3         79839-79979
            1618-1746           AC123029.3         80417-80545
            1747-1887           AC123029.3         82225-82365
            1888-2043           AC123029.3         82475-82630
            2044-2190           AC123029.3         82727-82873
            2191-2286           AC123029.3         82959-83054
            2287-2382           AC123029.3         83135-83230
            2383-3976           AC123029.3         83399-84992
FEATURES             Location/Qualifiers
     source          1..3976
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 1.95 cM"
     gene            1..3976
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /note="ecotropic viral integration site 5 like"
                     /db_xref="GeneID:213027"
                     /db_xref="MGI:MGI:2442167"
     exon            1..197
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            198..380
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             244..2670
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="EVI5-like protein isoform 2"
                     /protein_id="NP_001333659.2"
                     /db_xref="CCDS:CCDS85495.1"
                     /db_xref="GeneID:213027"
                     /db_xref="MGI:MGI:2442167"
                     /translation="MASPTLSPDSSSQEALSAPTCSPTSDSENLSPDELELLAKLEEQ
                     NRLLEADSKSMRSMNGSRRNSGSSLVSSSSASSNLSHLEEDTWILWGRIANEWEEWRR
                     RKEKLLKELIRKGIPHHFRAIVWQLLCSATDMPVKNQYSELLKMSSPCEKLIRRDIAR
                     TYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCV
                     FVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSWF
                     LTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQTELMQLDMEGMSQYFQRV
                     IPHQFDSCPDKLVLKAYQVKYNPKKMKRLEKEYAAMKSKEMEEQIEIKRLRTENRLLK
                     QRIETLEKESAALADRLIQGQVTRAQEAEENYVIKRELAVVRQQCSSTAEDLQKAQST
                     IRQLQEQQENPRLTEDFVAHLETELEQSRLRETETLGALREMQDKVLDMEKRNSSLPD
                     ENNVARLQEELKALKVREGEAVASARELKLQLQELSDTWQAHLSRGGRWKESPRKLVL
                     GELQDELMTVRLREAQALADGREWRQRVVELETQDNIHRNLLNRVEAERAALQEKLQY
                     LAAQNKGLQTQLSESRRKQAEAECKSKEEVMAVRLREADSMAAVAEMRQRIAELEIQR
                     EEGRIQGQLNHSDSSQYIRELKDQIEELKTEVRLLKGPPTFEDPLAFDGLSLTRHLDE
                     DSLPSSDEELLGVGVGVGAALQDPLYPLSPRDARFFRSLDRPAKDSEGSSDSDADELA
                     TPYSNQGLDN"
     exon            381..570
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            571..795
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            796..870
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            871..996
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            997..1140
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1141..1230
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1231..1328
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1329..1389
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1390..1443
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1444..1476
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1477..1617
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1618..1746
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1747..1887
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1888..2043
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2044..2190
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2191..2286
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2287..2382
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2383..3976
                     /gene="Evi5l"
                     /gene_synonym="1700084G18Rik; 2310039H16Rik;
                     3110007G05Rik; B130050I23Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcggctcct gtcagcgggt gaaatggcag tggcggagcc agcgacggcc gcggtccccg
       61 ggggtggctg attgaaaggg gccgggccgc ggggtttgcg ggaccctcga gcagacgtga
      121 ccgtgggtcg gggcatcgga cgacacagcg cagggacagc gaggctcggc gcggcgatgg
      181 aggcgctctc ggcgcagaca gagctgtaac ctggcatccc cctggctgat gagcctgccc
      241 accatggcaa gccccactct gagcccggac tcctcatctc aagaggccct gtcagcaccc
      301 acctgctccc caacctctga ctccgagaat ctcagcccag atgagctaga actactggcc
      361 aagctcgagg agcagaaccg gctcctggaa gccgactcca agtccatgcg ctccatgaat
      421 ggctcccgga ggaacagtgg ctcctcactg gtatccagct cctcagcctc ctccaacctg
      481 agccacctgg aggaggacac gtggattctc tggggccgaa ttgccaacga gtgggaggag
      541 tggcggcgca ggaaggaaaa actactcaag gagctgatcc ggaagggcat cccacaccac
      601 tttcgggcca tcgtctggca gctcctgtgc agtgccacag atatgcccgt caaaaaccag
      661 tactctgagc tcctcaagat gtcctcccca tgtgagaaac tcatcaggag ggatattgcc
      721 cgcacctacc cagagcatga attcttcaaa ggccaggaca gcctgggcca ggaagtcctc
      781 ttcaatgtca tgaaggcata ctccctggtt gatcgggagg tgggctactg ccagggcagt
      841 gccttcattg tgggcttact cctcatgcag atgcctgagg aagaggcctt ctgtgtattc
      901 gtgcgactga tgcaggagta ccggctacgg gagctcttca agcccagcat ggccgagctg
      961 ggactctgta tctaccagtt tgaatacatg ctacaggagc agcttccgga cctgaatacc
     1021 cacttccgct cacagagctt ccacacgtcc atgtatgcat cgtcctggtt ccttacgctt
     1081 ttccttacca ccttccccct gcctgttgcc acccgggtct ttgatatctt tatgtatgag
     1141 ggactggaga ttgtgttccg agtaggcctt gccctgctgc aagtgaacca gacagagttg
     1201 atgcaactgg acatggaggg catgtcccag tacttccaga gagtcatccc ccaccagttt
     1261 gacagctgcc cagacaagct ggtcctcaag gcttatcagg tcaagtacaa ccctaaaaag
     1321 atgaagaggc tggagaagga gtacgcagct atgaagagta aagagatgga ggagcagatc
     1381 gagatcaaaa ggcttcgaac agagaaccgg ctgctcaaac agcggattga gaccctagag
     1441 aaggagagcg cggccttggc tgataggtta atccaggggc aggtgacacg ggcacaggag
     1501 gctgaggaga actatgtcat caaacgggag ttggcagtag tgagacaaca gtgtagctcg
     1561 actgcagagg accttcagaa agcacagagt accattcggc agttgcaaga acagcaggaa
     1621 aaccctcgcc tcacagagga ctttgtggcc cacctggaga cagaactgga gcagtcacgg
     1681 ttacgagaaa cagagactct gggggccctt cgagaaatgc aggacaaagt tctggacatg
     1741 gaaaagagaa acagctcact gccagatgag aacaatgtag ccaggctgca ggaggaactc
     1801 aaggcactca aggtgcggga gggcgaggcc gtagcctctg ctcgggagct aaagctgcag
     1861 ctgcaggagc tctcagacac ctggcaggcc catctttccc gcggtggccg ctggaaggag
     1921 tccccgcgga agttggtcct gggcgagtta caggacgagc tcatgactgt gcgtttgcgc
     1981 gaggcacagg ccctggccga tggccgcgaa tggcggcagc gcgtggtgga actggagacg
     2041 caggacaaca ttcaccgcaa cctgctgaac cgtgtggagg cggaacgcgc ggccctgcag
     2101 gagaagttgc agtacctggc agcacagaac aagggactcc agactcagct cagcgaaagc
     2161 cgccgcaagc aggcagaggc tgagtgcaag agtaaggagg aagtgatggc tgttcgactt
     2221 cgggaggcag acagcatggc tgcagtggca gagatgaggc agcgcatcgc agagctggag
     2281 atccagaggg aggagggccg catccagggc cagctgaacc actcggattc atcgcagtac
     2341 atccgggagc tgaaggacca gatcgaggag ctcaagactg aggtgcggtt gctgaaaggc
     2401 ccaccgacat tcgaggaccc gctggctttc gatgggctca gcctaacgcg gcacctggat
     2461 gaggattcgc taccatcttc tgatgaggag ctgctgggcg tgggtgtggg cgtgggcgca
     2521 gccctgcagg acccactcta ccctctctct ccccgggacg cgcgcttctt cagaagcctg
     2581 gatcggccag ccaaggacag cgaaggtagc tcagacagcg atgcagatga actagccact
     2641 ccttatagca accagggcct ggacaactga agctgggggc ccactcacgg ggagcctgga
     2701 ggcccgcatt gctggcaggg agagatcagc agtccgcgag cttgctgctc cacagtacta
     2761 aggaattctg tgcctctgta actcctgcca actgagggcc aggtggagga ggcagcacag
     2821 aggggcaggg cctactggca ggcctgccct gcatagcagt gtttatccgt gttagaccat
     2881 attgtccaag ccctcctgag ttcaaggggt gcgtgggcca gttacctgga gggtgttgct
     2941 ctcctaacat ggacaagggc cgaaagtggg gaggccccag gacttgttaa taagcaggaa
     3001 gcttcctcct cctagtcagc ttccctttgg gacaagggag gccctgctgg gtggggccca
     3061 ggaactacag gtctgaggaa ggaggggcaa cttggactgg atattagcac cccaggacag
     3121 gttctctgga cacagtgata ttgagcagcc agtcccttgc cactggggac agatggccag
     3181 gctggacttt tctgcctggt gcaggcatca tggcccctgc agcagaaacc aaagccccca
     3241 gcccatcctg tctgcaggac ataccacctg gggtgtgagc agtcaggggg aaccagctca
     3301 gacctgggaa gtctctcccc actctctagg gctatagaag ctgcaaagaa gaaacccttt
     3361 ccctagagca cccatcttcc tctggggagt actaatatca cacgtgttgg ctggctgtaa
     3421 aagagagaac cccgctactt gggagttctc agcctcggtc catttattcc tgtggactta
     3481 ttccacttat tctggctaga gtttcccagt ccgttccctc cccttatctc ctcagagtat
     3541 tcccatggtc tctgcccagt cagagttgag aatggtgcca aagtccatca atgctcccca
     3601 ggctccttta cccttcaccc caccccaacc cgcatcttgg acccctgggg gctgacccct
     3661 tctcagtgct cctagagcct caagtagaat ggtgcccaca gcattccctg ggtgcttcct
     3721 gggtggggcc tccagctccg tttccattcc tggtggcctg ctcttcaagt gttaaaaaag
     3781 cctgggggct ggagcagggt acccctgagg aggccctctt gtgtgctcct catgtgcccc
     3841 tccacactgc ccaccaccat tttgcacact gcctgttcac actccatgtc tccaaggcag
     3901 aaaagatgga aaataaagtg tatttacaca gtcctaaggg atgccgaata gagagccaaa
     3961 gggctgggga atcaca
//
