LOCUS       NM_010161               1503 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus ecotropic viral integration site 2a (Evi2a),
            transcript variant 2, mRNA.
ACCESSION   NM_010161
VERSION     NM_010161.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1503)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1503)
  AUTHORS   Abdallah,B.M., Ditzel,N., Mahmood,A., Isa,A., Traustadottir,G.A.,
            Schilling,A.F., Ruiz-Hidalgo,M.J., Laborda,J., Amling,M. and
            Kassem,M.
  TITLE     DLK1 is a novel regulator of bone mass that mediates estrogen
            deficiency-induced bone loss in mice
  JOURNAL   J Bone Miner Res 26 (7), 1457-1471 (2011)
   PUBMED   21308776
REFERENCE   4  (bases 1 to 1503)
  AUTHORS   Venturin,M., Bentivegna,A., Moroni,R., Larizza,L. and Riva,P.
  TITLE     Evidence by expression analysis of candidate genes for congenital
            heart defects in the NF1 microdeletion interval
  JOURNAL   Ann Hum Genet 69 (Pt 5), 508-516 (2005)
   PUBMED   16138909
REFERENCE   5  (bases 1 to 1503)
  AUTHORS   Ivakine,E.A., Fox,C.J., Paterson,A.D., Mortin-Toth,S.M., Canty,A.,
            Walton,D.S., Aleksa,K., Ito,S. and Danska,J.S.
  TITLE     Sex-specific effect of insulin-dependent diabetes 4 on regulation
            of diabetes pathogenesis in the nonobese diabetic mouse
  JOURNAL   J Immunol 174 (11), 7129-7140 (2005)
   PUBMED   15905556
REFERENCE   6  (bases 1 to 1503)
  AUTHORS   Takahashi,Y., Shimizu,A., Sakai,T., Endo,Y., Osawa,N., Shisa,H. and
            Honjo,T.
  TITLE     Mapping of the nu gene using congenic nude strains and in situ
            hybridization
  JOURNAL   J Exp Med 175 (3), 873-876 (1992)
   PUBMED   1346798
REFERENCE   7  (bases 1 to 1503)
  AUTHORS   McAleer,M.A., Aitman,T.J., Cornall,R.J., Ghosh,S., Hall,J.R.,
            Hearne,C.M., Love,J.M., Prins,J.B., Ramachandran,S., Rodrigues,N.
            et al.
  TITLE     Linkage analysis of 84 microsatellite markers in intra- and
            interspecific backcrosses
  JOURNAL   Mamm Genome 3 (8), 457-460 (1992)
   PUBMED   1643308
REFERENCE   8  (bases 1 to 1503)
  AUTHORS   Frankel,W.N., Lee,B.K., Stoye,J.P., Coffin,J.M. and Eicher,E.M.
  TITLE     Characterization of the endogenous nonecotropic murine leukemia
            viruses of NZB/B1NJ and SM/J inbred strains
  JOURNAL   Mamm Genome 2 (2), 110-122 (1992)
   PUBMED   1311971
REFERENCE   9  (bases 1 to 1503)
  AUTHORS   Hogan,A., Heyner,S., Charron,M.J., Copeland,N.G., Gilbert,D.J.,
            Jenkins,N.A., Thorens,B. and Schultz,G.A.
  TITLE     Glucose transporter gene expression in early mouse embryos
  JOURNAL   Development 113 (1), 363-372 (1991)
   PUBMED   1765007
REFERENCE   10 (bases 1 to 1503)
  AUTHORS   Wilson,S.D., Billings,P.R., D'Eustachio,P., Fournier,R.E.,
            Geissler,E., Lalley,P.A., Burd,P.R., Housman,D.E., Taylor,B.A. and
            Dorf,M.E.
  TITLE     Clustering of cytokine genes on mouse chromosome 11
  JOURNAL   J Exp Med 171 (4), 1301-1314 (1990)
   PUBMED   1969921
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591174.13 and BC038124.1.
            
            On Sep 26, 2005 this sequence version replaced NM_010161.2.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC038124.1, SRR1660819.180183.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849389, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-241               AL591174.13        171031-171271
            242-1503            BC038124.1         199-1460
FEATURES             Location/Qualifiers
     source          1..1503
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 46.81 cM"
     gene            1..1503
                     /gene="Evi2a"
                     /gene_synonym="Evi-2; Evi2"
                     /note="ecotropic viral integration site 2a"
                     /db_xref="GeneID:14017"
                     /db_xref="MGI:MGI:95458"
     exon            1..241
                     /gene="Evi2a"
                     /gene_synonym="Evi-2; Evi2"
                     /inference="alignment:Splign:2.1.0"
     exon            242..1484
                     /gene="Evi2a"
                     /gene_synonym="Evi-2; Evi2"
                     /inference="alignment:Splign:2.1.0"
     CDS             262..933
                     /gene="Evi2a"
                     /gene_synonym="Evi-2; Evi2"
                     /note="protein EVI2A; EVI-2A; ecotropic viral integration
                     site 2A protein"
                     /codon_start=1
                     /product="protein EVI2A precursor"
                     /protein_id="NP_034291.1"
                     /db_xref="CCDS:CCDS25122.1"
                     /db_xref="GeneID:14017"
                     /db_xref="MGI:MGI:95458"
                     /translation="MEHKGQYLHLVFLMTTVWASSSSGTRPNYTHLWASSVTASGSSN
                     QNGSSRHPSDNNTNLVTPAVGHKVSATDKPASSPPVPLASTSTLKSSTPHAFRNSSPT
                     AEIKSQGETFKKEVCEENTSNTAMLICLIVIAVLFLICTFLFLSTVVLANKVSSLKRS
                     KQVGKRQPRSNGDFLASSGLWTAESDTWKRAKELTGSNLLLQSPGVLTAARERKHEEG
                     TEKLN"
     regulatory      1461..1466
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Evi2a"
                     /gene_synonym="Evi-2; Evi2"
                     /note="hexamer: AATGAA"
     polyA_site      1484
                     /gene="Evi2a"
                     /gene_synonym="Evi-2; Evi2"
                     /note="major polyA site"
ORIGIN      
        1 ttgtcatccc attgccagct ggacaagtca gtctttgctt tccccgtgac atgtagttga
       61 gttgcagcgg aaaggaaatg tgtcatctgt ggtttggttt taagagtgga aagctagctg
      121 tacatatcct ctttaaaaaa ccctgcagat ttaagtttca cagtctccaa agtattctac
      181 ttaaaataag aagagcagaa ctgaggtggc ttacgaagtg acggctgggc gagctctgaa
      241 gatagcagtg gacctgtagg tatggagcac aaaggacagt acctgcatct tgttttcctg
      301 atgacaacag tgtgggcctc gtcgtcttct ggaacaagac caaactacac acacctgtgg
      361 gctagcagtg tcactgcctc aggttccagt aatcagaatg gctccagcag acatccgagt
      421 gacaataaca caaaccttgt cactcctgcc gtgggtcaca aggtgagcgc cacagacaag
      481 cctgcatcat ctccccctgt gcctttagct tccacatcta cactcaagtc ctccacgccc
      541 catgccttca gaaacagttc tccaacagca gagatcaaaa gtcaggggga aacgtttaaa
      601 aaggaagtct gtgaggagaa caccagcaac acggccatgc taatttgctt aattgtaatt
      661 gcagtgcttt tccttatctg tacctttcta tttctatcaa ctgtggttct ggcaaacaaa
      721 gtctcatctc tcaaaaggtc aaagcaagta ggcaagcgcc agccgcggag caacggtgac
      781 tttctggcaa gtagtgggct ctggactgct gagtcggaca cttggaaaag agcaaaggag
      841 ctcacaggct ccaacctcct attgcaatct cctggtgtgc ttacagcagc cagggagaga
      901 aagcacgaag aaggaactga aaaactcaac taggctgtgg gttggaaagg gaaatgcaaa
      961 gcagcaatga ggaaggcaga gttagaaata aagctggctg gtggtatttc ccatccacgt
     1021 ttgctcagat gatccaaagt ctgacatgct ctttgtttag cgtcagacca gaaagggaga
     1081 tgtatgcttg ctcaaggttt atatctgttt cgtacttcat atttttaaga aagtaaaaca
     1141 acagcagcta aagaaactaa tagaaataac atgaggtaat taaacattcc tgttcagcag
     1201 tgaatgacct ctgtctgaat gtacttgaac ttggaagagt tcttttaagc ccttagagcc
     1261 aagcagatgt caaattccca atgtgtagaa ttcaactatg taacgcaatg gtacattctc
     1321 actggatgag atagaacctg taccagttgc tatcttagta cagctaatat taggctacat
     1381 ctttttacct ttacatatgg cgtaagacaa gactgctttt ctattataca taacacatta
     1441 aaacttaatt ttgtacaata aatgaaaaca gactttagaa caaaaaaaaa aaaaaaaaaa
     1501 aaa
//
