LOCUS       NM_023794               3847 bp    mRNA    linear   ROD 11-FEB-2025
DEFINITION  Mus musculus ets variant 5 (Etv5), transcript variant 2, mRNA.
ACCESSION   NM_023794
VERSION     NM_023794.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3847)
  AUTHORS   Franks,N.E. and Allen,B.L.
  TITLE     Hedgehog-dependent and hedgehog-independent roles for growth arrest
            specific 1 in mammalian kidney morphogenesis
  JOURNAL   Development 151 (24) (2024)
   PUBMED   39629522
REFERENCE   2  (bases 1 to 3847)
  AUTHORS   Patel,V.N., Aure,M.H., Choi,S.H., Ball,J.R., Lane,E.D., Wang,Z.,
            Xu,Y., Zheng,C., Liu,X., Martin,D., Pailin,J.Y., Prochazkova,M.,
            Kulkarni,A.B., van Kuppevelt,T.H., Ambudkar,I.S., Liu,J. and
            Hoffman,M.P.
  TITLE     Specific 3-O-sulfated heparan sulfate domains regulate salivary
            gland basement membrane metabolism and epithelial differentiation
  JOURNAL   Nat Commun 15 (1), 7584 (2024)
   PUBMED   39217171
  REMARK    Erratum:[Nat Commun. 2024 Oct 10;15(1):8784. doi:
            10.1038/s41467-024-53230-4.. PMID: 39389981]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3847)
  AUTHORS   Park,J., Lee,J., Hur,Y., Kim,C.J., Kim,H.B., Um,D., Kim,D.S.,
            Lee,J.Y., Park,S., Park,Y., Kim,T.K., Im,S.H., Kim,S.W., Kwok,S.K.
            and Lee,Y.
  TITLE     ETV5 promotes lupus pathogenesis and follicular helper T cell
            differentiation by inducing osteopontin expression
  JOURNAL   Proc Natl Acad Sci U S A 121 (24), e2322009121 (2024)
   PUBMED   38843187
  REMARK    GeneRIF: ETV5 promotes lupus pathogenesis and follicular helper T
            cell differentiation by inducing osteopontin expression.
REFERENCE   4  (bases 1 to 3847)
  AUTHORS   Sun,M., Gao,Y., Li,Z., Yang,L., Liu,G., Xu,Z., Guo,R., You,Y. and
            Yang,Z.
  TITLE     ERK signaling expands mammalian cortical radial glial cells and
            extends the neurogenic period
  JOURNAL   Proc Natl Acad Sci U S A 121 (13), e2314802121 (2024)
   PUBMED   38498715
REFERENCE   5  (bases 1 to 3847)
  AUTHORS   D'Cruz,R., Kim,Y.K., Mulder,J., Ibeh,N., Jiang,N., Tian,Y. and
            Rosenblum,N.D.
  TITLE     Hedgehog signalling in Foxd1+ embryonic kidney stromal progenitors
            controls nephron formation via Cxcl12 and Wnt5a
  JOURNAL   J Pathol 261 (4), 385-400 (2023)
   PUBMED   37772431
REFERENCE   6  (bases 1 to 3847)
  AUTHORS   Chotteau-Lelievre,A., Montesano,R., Soriano,J., Soulie,P.,
            Desbiens,X. and de Launoit,Y.
  TITLE     PEA3 transcription factors are expressed in tissues undergoing
            branching morphogenesis and promote formation of duct-like
            structures by mammary epithelial cells in vitro
  JOURNAL   Dev Biol 259 (2), 241-257 (2003)
   PUBMED   12871699
  REMARK    GeneRIF: ERM is a transcription factor in the ets family, within
            which it forms the PEA3 group.
REFERENCE   7  (bases 1 to 3847)
  AUTHORS   Hippenmeyer,S., Shneider,N.A., Birchmeier,C., Burden,S.J.,
            Jessell,T.M. and Arber,S.
  TITLE     A role for neuregulin1 signaling in muscle spindle differentiation
  JOURNAL   Neuron 36 (6), 1035-1049 (2002)
   PUBMED   12495620
REFERENCE   8  (bases 1 to 3847)
  AUTHORS   Liu,Y. and Hogan,B.L.
  TITLE     Differential gene expression in the distal tip endoderm of the
            embryonic mouse lung
  JOURNAL   Gene Expr Patterns 2 (3-4), 229-233 (2002)
   PUBMED   12617806
REFERENCE   9  (bases 1 to 3847)
  AUTHORS   Chotteau-Lelievre,A., Dolle,P., Peronne,V., Coutte,L., de
            Launoit,Y. and Desbiens,X.
  TITLE     Expression patterns of the Ets transcription factors from the PEA3
            group during early stages of mouse development
  JOURNAL   Mech Dev 108 (1-2), 191-195 (2001)
   PUBMED   11578874
REFERENCE   10 (bases 1 to 3847)
  AUTHORS   Chotteau-Lelievre,A., Desbiens,X., Pelczar,H., Defossez,P.A. and de
            Launoit,Y.
  TITLE     Differential expression patterns of the PEA3 group transcription
            factors through murine embryonic development
  JOURNAL   Oncogene 15 (8), 937-952 (1997)
   PUBMED   9285689
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC034680.1.
            
            On Nov 4, 2002 this sequence version replaced NM_023794.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC034680.1, AK168881.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3847
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 13.3 cM"
     gene            1..3847
                     /gene="Etv5"
                     /gene_synonym="1110005E01Rik; 8430401F14Rik; ERM"
                     /note="ets variant 5"
                     /db_xref="GeneID:104156"
                     /db_xref="MGI:MGI:1096867"
     exon            1..54
                     /gene="Etv5"
                     /gene_synonym="1110005E01Rik; 8430401F14Rik; ERM"
                     /inference="alignment:Splign:2.1.0"
     exon            55..177
                     /gene="Etv5"
                     /gene_synonym="1110005E01Rik; 8430401F14Rik; ERM"
                     /inference="alignment:Splign:2.1.0"
     CDS             133..1665
                     /gene="Etv5"
                     /gene_synonym="1110005E01Rik; 8430401F14Rik; ERM"
                     /note="ets variant gene 5"
                     /codon_start=1
                     /product="ETS translocation variant 5"
                     /protein_id="NP_076283.2"
                     /db_xref="CCDS:CCDS37299.1"
                     /db_xref="GeneID:104156"
                     /db_xref="MGI:MGI:1096867"
                     /translation="MDGFCDQQVPFMVPGKSRSEDCRGRPLIDRKRKFVDTDLAHDSE
                     ELFQDLSQLQEAWLAEAQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSSC
                     SHEQALGAKYGEKCLYNYCAYDRKPPSGFKPLTPPATPLSPTHQNSLFPPPQATLPTS
                     GLTPGAGPVQGVGPAPTPHSLPEPGSQQQTFAVPRPPHQPLQMPKMMPESQYPSEQRF
                     QRQLSEPSHPFPPQSGVPGDSRPSYHRQMSEPIVPAAPPPLQGFKQEYHDPLYEHGVP
                     GMPGPPAHGFQSPMGIKQEPRDYCADSEVPNCQSSYMRGGYFSSSHEGFPYEKDPRLY
                     FDDTCVVPERLEGKVKQEPTMYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGR
                     GMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCD
                     PDALFSMAFPDNQRPFLKAESECPLNEEDTLPLTHFEDNPAYLLDMDRCSSLPYTEGF
                     AY"
     exon            178..265
                     /gene="Etv5"
                     /gene_synonym="1110005E01Rik; 8430401F14Rik; ERM"
                     /inference="alignment:Splign:2.1.0"
     exon            266..313
                     /gene="Etv5"
                     /gene_synonym="1110005E01Rik; 8430401F14Rik; ERM"
                     /inference="alignment:Splign:2.1.0"
     exon            314..364
                     /gene="Etv5"
                     /gene_synonym="1110005E01Rik; 8430401F14Rik; ERM"
                     /inference="alignment:Splign:2.1.0"
     exon            365..494
                     /gene="Etv5"
                     /gene_synonym="1110005E01Rik; 8430401F14Rik; ERM"
                     /inference="alignment:Splign:2.1.0"
     exon            495..782
                     /gene="Etv5"
                     /gene_synonym="1110005E01Rik; 8430401F14Rik; ERM"
                     /inference="alignment:Splign:2.1.0"
     exon            783..1042
                     /gene="Etv5"
                     /gene_synonym="1110005E01Rik; 8430401F14Rik; ERM"
                     /inference="alignment:Splign:2.1.0"
     exon            1043..1102
                     /gene="Etv5"
                     /gene_synonym="1110005E01Rik; 8430401F14Rik; ERM"
                     /inference="alignment:Splign:2.1.0"
     exon            1103..1171
                     /gene="Etv5"
                     /gene_synonym="1110005E01Rik; 8430401F14Rik; ERM"
                     /inference="alignment:Splign:2.1.0"
     exon            1172..1341
                     /gene="Etv5"
                     /gene_synonym="1110005E01Rik; 8430401F14Rik; ERM"
                     /inference="alignment:Splign:2.1.0"
     exon            1342..1443
                     /gene="Etv5"
                     /gene_synonym="1110005E01Rik; 8430401F14Rik; ERM"
                     /inference="alignment:Splign:2.1.0"
     exon            1444..3822
                     /gene="Etv5"
                     /gene_synonym="1110005E01Rik; 8430401F14Rik; ERM"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggcccagc ccgccacgga ggcgcgcagg cgggcgcgcg gagtggccgc tcaggagtat
       61 ctctttacca cccccaagaa actactcaat gctgaagccc ttcaaagtga tagcggagac
      121 tttggaagca ccatggatgg gttttgtgat cagcaagtcc cttttatggt cccagggaaa
      181 tctcgatcag aggactgtcg agggcgacct ttgattgaca gaaagaggaa gtttgtggac
      241 acagatctgg ctcacgattc tgaagagttg tttcaggatc ttagccagct gcaggaggct
      301 tggttagctg aagcacaagt tcctgatgat gagcagtttg tcccagattt tcagtctgat
      361 aacttggtgc ttcatgctcc acctcccacc aagatcaaac gggagctgca cagcccctcc
      421 tccgagttgt cgtcctgtag ccacgagcag gctcttggtg ctaagtatgg agaaaagtgc
      481 ctctacaact attgtgccta cgataggaag cctccctctg ggttcaagcc attaaccccg
      541 cccgccactc ctctgtcacc cacccatcag aattccctat ttcccccacc tcaggcaact
      601 ctgcccacct caggtctcac ccctggagct ggcccagttc aaggggtggg tcctgccccg
      661 actcctcact cacttccaga acctggatca cagcaacaaa catttgcggt cccccggcca
      721 ccacatcagc ccctgcaaat gccaaagatg atgcctgaaa gccagtatcc atcagaacag
      781 agatttcagc gacagctgtc tgagcccagc catcccttcc ctcctcagtc aggagttcct
      841 ggagatagtc gccccagcta ccaccggcag atgtcagagc ccattgtccc cgcagctccg
      901 ccaccccttc agggattcaa gcaggaatac catgacccac tgtatgaaca tggggtccct
      961 gggatgcctg gtcctccagc acatgggttc cagtcaccca tggggatcaa gcaggagccc
     1021 cgagattact gtgctgactc agaagtgcct aactgccagt catcctacat gagaggcggg
     1081 tatttctcca gcagccatga aggattcccg tatgagaagg accccaggct gtactttgat
     1141 gatacttgcg tggtacccga gagactggaa ggcaaagtca agcaggagcc caccatgtat
     1201 cgagaggggc ctccttatca gagacgaggc tctctgcagc tgtggcagtt ccttgtcacc
     1261 ctcctggatg acccagccaa tgcccacttc atcgcctgga ctggccgagg catggaattt
     1321 aagctcatag aaccggaaga ggttgctcgc cgttggggta tccagaagaa tcggccagcc
     1381 atgaactatg acaagctgag ccgctctctc cgctattact atgaaaaggg catcatgcag
     1441 aaggtggctg gggaacgcta cgtctacaaa tttgtgtgtg acccggatgc actcttctct
     1501 atggccttcc cggacaatca gcgcccgttc ctgaaggcag aatccgaatg ccccctcaat
     1561 gaggaggaca cgctgcctct gactcacttt gaagacaacc ctgcttacct cctggacatg
     1621 gatcgctgca gcagcctccc ctacaccgaa ggcttcgctt actaagtttc tgaatggccg
     1681 agtagccaca ccctagagct agcagtcctc atccaggcaa ccgagggcag tggttttgtt
     1741 tgtgttcttg gctgttccta aagcttgccc tttgagtatt atcaggagaa cccaagctgt
     1801 ctctggattc gacacccttt aagacaaata ccttggctcg ggaggagtgg gaacagggag
     1861 agacaaaaac caccacttcc tggggagacg tggataccgt cctccttgcc accatggcca
     1921 gtatgtgcag agcagtactg cagtgtgttc agggttagcg cccatgaaag gggaccgagt
     1981 gtatgacaat ctgcgttgat catggactac taaaatgcct tcacacagga ggctttgact
     2041 tgcacaattc tttgggaaga aactgcacac ccataggaca gtcgataagg ctgagtcggg
     2101 gaggctcaga ccattgaggc ttgaaattgc aaaactcttg tagctcattc tgaaatcttt
     2161 cccctgtagt ccagaactgg ggaggccagg agagccgtta ctcactccat ggctctcaga
     2221 ccgcgttcct ctttggcctt ccttccagcc gagccgtcac cataagtaaa tcaagtccct
     2281 tcctcccagt cacacggctg agcgcagacg gcttgtttta aaaagatgat gaacatgaca
     2341 gtattttgtt ttgctttgat ttggggggga agggttcatc ttgcttttgg aggttgtttt
     2401 ggggaaaaaa cagtttatat aaactgattt ttgtagtttt ggtatttaaa gcaaaaacaa
     2461 acaaaaaaca aacccctttt tggtacctgc actgcatccc tcgggtgggg cagtgcctac
     2521 tttggaagat gctgcagcct gcgaggggat ctgctggggc ttccccttcg ccacacagaa
     2581 gcctgcttag tgctttctgc accagacaac ctgttgaggc gtataacctg atctgtacat
     2641 ttttttaagt gtgcagggca gcctggacac agcttagcgt tctacgtgta tagttctcca
     2701 tgctcactaa ctctccttct ctgggaagca gatgtacata ctacatacat gtcacatact
     2761 acatacatgt catgtactac acacatgtca tatagtacat acatgtcatg tccatttaac
     2821 gactggtcac ctgctgggga cccaggcatc tgccttgttt tcctttttct ttcagttttg
     2881 gactttggac cctgcacagc cgttccccag ggtctgaaac ttacctgtca cgcacaggta
     2941 gagcagtgct agctagcatt actggcttcc tgctactttt tcgttttttt aaatttttta
     3001 ttctgattgc tgtattatat tggggatgtt ctaaacaacc aaactaaagc tgtgtacaga
     3061 ttgggtttgg agcggtgggg acgtcagcag gaaacgccag tgctttgctg cctgattgac
     3121 aggaatttgc tgtccttgac actccacaca ttgtgttcct cacgtgtggg acaggacaca
     3181 gagctgactg agcgtgggac actccacagc cttctcatga cttgtgaagg aggttcacag
     3241 gaacgagggg tatgttttag agctatgaga acctagtcag cccacagagg cgtcaaacct
     3301 gaagcttggg ccttaattag cattgtactc tgatgaaagg actctttcat aagcatattt
     3361 atagctttct aatctataca cagtctatcc atagatgcat attttacccc aactggctag
     3421 agatttattt gttgtaaatg ctgtatagat tttgggtttt ttttttttgt tcttcctctc
     3481 ttcacttata ctggtgtggg gtttgtttta gttttcttta gtgaatttat gctgttttgg
     3541 ggggcggatt gagaagaatc ttccgtagcc tgagctgtcc ctcctgtttt gacggcacat
     3601 gtgccagtca agggacatgg gacagtcgcg ccactttgca ttcccacggg actcatgtac
     3661 ctcccgcaga gccgtccccg tcaaggtgtg gggctccttt catgcatttg cttcttttcc
     3721 agagtgtgga tttgaactac ttccccctgc aaagggccgc gtgcaccctg ccgagctgcg
     3781 tatattctgt actgtgtaca ataaagaaga ttgctttcct taaaaaaaaa aaaaaaaaaa
     3841 aaaaaaa
//
