LOCUS       NM_027907               2704 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus ethanolamine phosphate phospholyase (Etnppl),
            transcript variant 1, mRNA.
ACCESSION   NM_027907
VERSION     NM_027907.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2704)
  AUTHORS   Tsujioka,H. and Yamashita,T.
  TITLE     Utilization of ethanolamine phosphate phospholyase as a unique
            astrocytic marker
  JOURNAL   Front Cell Neurosci 17, 1097512 (2023)
   PUBMED   36794261
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2704)
  AUTHORS   White,C.J., Ellis,J.M. and Wolfgang,M.J.
  TITLE     The role of ethanolamine phosphate phospholyase in regulation of
            astrocyte lipid homeostasis
  JOURNAL   J Biol Chem 297 (1), 100830 (2021)
   PUBMED   34048714
  REMARK    GeneRIF: The role of ethanolamine phosphate phospholyase in
            regulation of astrocyte lipid homeostasis.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK005060.1 and BC058592.1.
            
            On Jul 24, 2009 this sequence version replaced NM_027907.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 both encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058592.1, AK005060.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN00849386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-38                AK005060.1         2-39
            39-2704             BC058592.1         1-2666
FEATURES             Location/Qualifiers
     source          1..2704
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 60.47 cM"
     gene            1..2704
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /note="ethanolamine phosphate phospholyase"
                     /db_xref="GeneID:71760"
                     /db_xref="MGI:MGI:1919010"
     exon            1..174
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..1618
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /EC_number="4.2.3.2"
                     /note="alanine--glyoxylate aminotransferase 2-like 1"
                     /codon_start=1
                     /product="ethanolamine-phosphate phospho-lyase"
                     /protein_id="NP_082183.2"
                     /db_xref="CCDS:CCDS38638.1"
                     /db_xref="GeneID:71760"
                     /db_xref="MGI:MGI:1919010"
                     /translation="MCELYSKQDTLALRERHIGPSCKIFFAADPIKIMRAQGQYMFDE
                     KGERYLDCINNVAHVGHCHPEVVKAAAKQMELLNTNSRFLHDNIIEFAKRLTATLPQE
                     LSVCYFTNSGSEANDLALRLARQFRGHQDVITLDHAYHGHLSSLIEISPYKFQKGKDV
                     KRETVHVAPAPDTYRGKYREDHEDPSTAYADEVKKIIEEAHSSGRKIAAFIAESMQSC
                     GGQIIPPAGYFQKVAEHIHKAGGVFIADEVQVGFGRVGRYFWSFQMYGEDFVPDIVTM
                     GKPMGNGHPISCVVTTKEIAEAFSSSGMEYFNTYGGNPVSCAVGLAVLDVIEKENLQG
                     NAVRVGTYLMELLSEQKAKHPLIGDIRGVGLFIGIDLVKDREKRTPATAEAQHIIYEM
                     KGKGVLLSADGPHRNVLKIKPPMCFTEDDAKFLVDHLDGILTVLEEAMDSKSGTVFSE
                     NTAYRTKMPKEIQVELPNLSATEAREIPRGKRNGVCSDQQALLSKRLKT"
     exon            175..293
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            294..453
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            454..528
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            529..619
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            620..736
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            737..819
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            820..1045
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1046..1200
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1201..1290
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1291..1421
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1422..1489
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1490..2691
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1745..1750
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /note="hexamer: AATAAT"
     polyA_site      1785
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /note="major polyA site"
     regulatory      2670..2675
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
                     /note="hexamer: AATAAA"
     polyA_site      2691
                     /gene="Etnppl"
                     /gene_synonym="1300019H02Rik; Agxt2l1"
ORIGIN      
        1 gccactagtg acctccgata cccagggcag gaggcacagg aggggagaaa aaaaatcctt
       61 tgcagcgtcc caggttacag agggaggaac attcattgac ttgaagggtg cagcggtcat
      121 gtgcgagctc tatagcaagc aggacaccct ggcgctgagg gagaggcaca tcgggccctc
      181 gtgcaaaatt ttctttgccg cggatcccat caaaataatg cgagcccagg ggcagtacat
      241 gtttgatgag aaaggcgaac ggtacttaga ctgcatcaac aacgtggcgc atgtgggaca
      301 ctgtcaccca gaagtggtca aagctgccgc gaaacagatg gaattactaa atacaaattc
      361 tcgcttcctc cacgacaaca tcattgagtt tgccaagcgc cttactgcca ccctgcctca
      421 ggagctctcc gtttgctact tcacaaactc cggatccgaa gccaatgact tagccttacg
      481 tctggcacgg cagttccgag gccaccagga tgtgatcacc cttgaccatg cttaccacgg
      541 ccacctgtcg tcattaattg agatcagtcc ttataagttt cagaagggca aagatgtcaa
      601 gagggaaact gtacatgtgg caccagctcc agacacttac agagggaaat acagagagga
      661 ccacgaagac ccatccactg catatgccga cgaggtgaag aagatcattg aagaggctca
      721 cagcagcgga aggaagattg ctgcctttat tgctgaatcc atgcagagtt gtggtggaca
      781 aattattcct ccagcaggct acttccagaa agtggctgaa cacattcaca aagcaggagg
      841 tgtgttcatt gctgacgaag ttcaagtagg ctttggcaga gttgggaggt acttctggag
      901 cttccagatg tatggtgaag acttcgttcc agacatcgtc accatgggga aacctatggg
      961 caacggtcac ccgatatcct gtgtggtgac aaccaaagaa attgcagaag ccttcagcag
     1021 ctcgggcatg gaatatttca atacgtatgg aggaaatcca gtgtcttgtg cagttggctt
     1081 ggctgtgctg gatgtaattg aaaaggagaa ccttcaaggg aatgctgtca gagtggggac
     1141 ctatctcatg gagctgctga gtgaacagaa ggctaagcat cccttgatag gggacatcag
     1201 aggtgtcggc ctttttatcg gcatcgattt ggtgaaggac cgtgagaaaa gaacacctgc
     1261 gacagctgaa gcacagcaca tcatctacga gatgaaagga aagggggtac ttctcagtgc
     1321 cgatggccct cacaggaacg tgctgaaaat aaaaccaccc atgtgcttca cggaagacga
     1381 tgcaaagttc ctggtggacc accttgacgg cattttaaca gttttagaag aagccatgga
     1441 ctccaagagt ggaactgtgt tctctgagaa cacagcttac agaacaaaga tgcctaagga
     1501 aatacaagtg gaattgccca accttagtgc caccgaggcc agagaaatcc ccaggggaaa
     1561 gagaaatggt gtatgctcag accagcaagc cctgctcagc aaaagactca agacatgaga
     1621 gctgagtgct aaacagtgga taaatatcca ggaacacagt gtgcaagtgg atgcatctca
     1681 tctcttagtg atcctttaaa ttgcaatttt caatctgtct aacttgtaca ttaaaagata
     1741 gattaataat atcaatgatc aaagtgataa actatgtcaa cattattgat tgagcctctt
     1801 gtctgataat tcattgcctg taattctaaa gttatttatt ctactaaaac tgagttttcc
     1861 tttgcaagac taagctgggt gccttgcttc tcacattgcc atgtttgaaa ttagagaaaa
     1921 agtgaagtct atttcttcac gtcagagagt tagtatactg aagtattttt aatcacaaga
     1981 aatgctctaa aacggttgat ataaaaactt tatttctaga ttttaataaa ataaaagacg
     2041 atctaacaaa aatgaagact ataaaatgta gagagctctg taggttatgg tggtgaaatc
     2101 taaatcgttc tgaaaggaaa tcacagagct gagaggaaaa tggcaaagaa gagcggttgg
     2161 taagaaacct ggttatttgc catgttgtgg gaactggaag ggaacacata cacagagacc
     2221 cttgcgtgag gaagttccta gagtgacaga agcagccaaa gcccagcatt cagggttggg
     2281 gactttgatt ctggctactc acaggctatg ccaccttgac caagttgctc acctatcagg
     2341 taaaaatggc ccctcctccg aacaccttat tttccccaac ttcattatca cctgcatccc
     2401 actgtcctaa attaccttcg tctgacctgt atctctctat tgccttccta ctagttatta
     2461 aacttgctgg tttgttttta ttccgtaaag aagagacagc aacttttcta tgcctgttta
     2521 ctgttaactg agtgagatgt ctcctttgga gtatgagcct gttctttgga taatggtaat
     2581 tcagggaact tcttgtctgt ggttaacaca tgtggaaagc cttggattgt ggtcctgaaa
     2641 gtctgttcaa aagacaaaaa aaataaaaaa ataaaaacaa ggcaaactga aaaaaaaaaa
     2701 aaaa
//
