LOCUS       NM_175443               2280 bp    mRNA    linear   ROD 17-DEC-2022
DEFINITION  Mus musculus ethanolamine kinase 2 (Etnk2), mRNA.
ACCESSION   NM_175443 XM_489809
VERSION     NM_175443.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2280)
  AUTHORS   Gustin SE, Western PS, McClive PJ, Harley VR, Koopman PA and
            Sinclair AH.
  TITLE     Testis development, fertility, and survival in Ethanolamine kinase
            2-deficient mice
  JOURNAL   Endocrinology 149 (12), 6176-6186 (2008)
   PUBMED   18755794
  REMARK    GeneRIF: No abnormalities were detected in the Eki2-deficient mice
            with regard to embryonic and adult testis morphology,
            differentiation, function, or fertility.
REFERENCE   2  (bases 1 to 2280)
  AUTHORS   Tian Y, Jackson P, Gunter C, Wang J, Rock CO and Jackowski S.
  TITLE     Placental thrombosis and spontaneous fetal death in mice deficient
            in ethanolamine kinase 2
  JOURNAL   J Biol Chem 281 (38), 28438-28449 (2006)
   PUBMED   16861741
REFERENCE   3  (bases 1 to 2280)
  AUTHORS   Hurley TM, McClive PJ, Sarraj MA and Sinclair AH.
  TITLE     Eki2 is upregulated specifically in the testis during mouse sex
            determination
  JOURNAL   Gene Expr Patterns 4 (2), 135-140 (2004)
   PUBMED   15161093
  REMARK    GeneRIF: Expression restricted to the Sertoli cells of the
            developing testis.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ170618.1, AK077179.1 and AU256212.1.
            
            [WARNING] On Apr 12, 2023 this sequence was replaced by
            NM_175443.6.
            
            On Oct 16, 2007 this sequence version replaced NM_175443.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077179.1, BC152310.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-262               CJ170618.1         1-262
            263-2276            AK077179.1         2-2015
            2277-2280           AU256212.1         217-220
FEATURES             Location/Qualifiers
     source          1..2280
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1"
     gene            1..2280
                     /gene="Etnk2"
                     /gene_synonym="4933417N20Rik; EKI 2; Eki2; Tuc1"
                     /note="ethanolamine kinase 2"
                     /db_xref="GeneID:214253"
                     /db_xref="MGI:MGI:2443760"
     exon            1..447
                     /gene="Etnk2"
                     /gene_synonym="4933417N20Rik; EKI 2; Eki2; Tuc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             193..1350
                     /gene="Etnk2"
                     /gene_synonym="4933417N20Rik; EKI 2; Eki2; Tuc1"
                     /EC_number="2.7.1.82"
                     /note="putative ethanolamine kinase; ethanolamine
                     kinase-like protein"
                     /codon_start=1
                     /product="ethanolamine kinase 2"
                     /protein_id="NP_780652.2"
                     /db_xref="CCDS:CCDS15296.2"
                     /db_xref="GeneID:214253"
                     /db_xref="MGI:MGI:2443760"
                     /translation="MAVPPSAPVPCSPFYLRRQEPCPQCSWSMEEKAVASAGCWEPPG
                     PPRAAVPCFSVTVEQDDILPGALRLIRELRPHWKPEQVRTKRFKDGITNKLLACYVEE
                     DMRDCVLVRVYGERTELLVDRENEVRNFQLLRAHGCAPKLYCTFQNGLCYEYVQGVAL
                     GPEHIREPQLFRLIALEMAKIHTIHANGSLPKPTLWHKMHRYFTLVKDEISPSLSADV
                     PKVEVLEQELAWLKEHLSQLDSPVVFCHNDLLCKNIIYDSDKGRVCFIDYEYAGYNYQ
                     AFDIGNHFNEFAGVNVVDYSRYPARETQVQWLRYYLEAQKGTAASPREVERLYAQVNK
                     FALASHFFWALWALIQNQYSTISFDFLRYAVIRFNQYFKVKPQVSALEMPK"
     exon            448..707
                     /gene="Etnk2"
                     /gene_synonym="4933417N20Rik; EKI 2; Eki2; Tuc1"
                     /inference="alignment:Splign:2.1.0"
     exon            708..830
                     /gene="Etnk2"
                     /gene_synonym="4933417N20Rik; EKI 2; Eki2; Tuc1"
                     /inference="alignment:Splign:2.1.0"
     exon            831..973
                     /gene="Etnk2"
                     /gene_synonym="4933417N20Rik; EKI 2; Eki2; Tuc1"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1057
                     /gene="Etnk2"
                     /gene_synonym="4933417N20Rik; EKI 2; Eki2; Tuc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1203
                     /gene="Etnk2"
                     /gene_synonym="4933417N20Rik; EKI 2; Eki2; Tuc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1204..1277
                     /gene="Etnk2"
                     /gene_synonym="4933417N20Rik; EKI 2; Eki2; Tuc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1278..2279
                     /gene="Etnk2"
                     /gene_synonym="4933417N20Rik; EKI 2; Eki2; Tuc1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgtcgcggcg gaccttggcg attcccggcc agctgtgttg ctcggttgca tcgccggaga
       61 ttggaacagg cagctcgctc atgagtcatg gacttcccct ggcccctcct cgaccactcc
      121 cactctctct cagggccccc ccgtaggggc taacgcgggc gcggcggctc cgagggggtg
      181 gggctgctgg gaatggctgt gcccccttca gctccagtgc cgtgctcgcc cttttacctg
      241 cggaggcagg agccttgccc gcagtgctca tggagcatgg aggagaaggc ggtggccagc
      301 gccggctgct gggagcctcc agggcccccg agggccgccg tcccatgctt cagcgtcacg
      361 gtggaacagg acgacatcct ccccggtgcc ctgcgcctca ttcgggagct gcggccgcac
      421 tggaagcccg aacaagttcg gaccaagcgc ttcaaagacg gcatcaccaa caagctattg
      481 gcctgctatg tggaggagga catgcgggac tgcgtgttgg tccgggtgta tggggagcgc
      541 acggagttgc tggtggaccg ggagaatgag gtcagaaact tccaactgct gcgagcacac
      601 ggctgcgccc ccaaactcta ctgtaccttt cagaacgggc tgtgctacga gtatgtgcag
      661 ggtgtggccc tgggacctga acacatccga gagccccagc tcttcaggtt gatcgcctta
      721 gaaatggcta agattcacac catccacgcc aatggcagcc tgcctaagcc cacgctctgg
      781 cataagatgc atcgttattt cacgctggtc aaggatgaga tcagtcccag cctttctgca
      841 gatgtcccca aagtggaggt gttggaacag gagctggcct ggttgaagga acacctgtcc
      901 cagttggatt cccctgtggt gttctgtcac aatgatctac tctgcaagaa tatcatctat
      961 gacagtgaca aaggccgcgt gtgctttatt gactatgaat atgcagggta caactaccag
     1021 gcatttgaca ttggcaacca tttcaatgag tttgcaggtg tgaatgtggt tgattacagc
     1081 cggtatccag ctcgggagac ccaggtgcag tggctgcgtt attatcttga ggcgcagaag
     1141 gggacagctg catcccccag ggaggtggag cggctttatg cacaagtcaa caaattcgct
     1201 ctggcatctc atttcttctg ggcactctgg gcactcatac agaaccagta ttctaccatc
     1261 agctttgact tcctcaggta tgcggtgatc cgattcaacc agtactttaa ggtgaaacct
     1321 caggtgtcgg ccttggagat gccaaaatga ccagcctcct gtttctccat gtcctcttgc
     1381 tgccagatct gctccccagg gtgcctttct gccttggagt tgggcaccct ggggcaaggc
     1441 gggcacccac ggagaaggct cccagtggat gccaatgaag acctcatttt cctgtttgga
     1501 ggggctgagt cccagcattg ggcgtgggga aaacccttca tcctgctagg cttggagagg
     1561 aagtgcctgc agatagtggg ggggcctgga ctgcccccct gtgagagcac agttgccagc
     1621 ccaggcactg ctagagcttg ggctgcctca gtttgtcctt gacccttcct agtaggggag
     1681 gggagggttc atttctacct ctggtgcccc acccccaccc caggcctcca actgagccgt
     1741 atgcctcctg tgagaggtac tgagctccaa gccagcagga agccaactct ggcttgtcat
     1801 cctggggaga ggtcccagct gcactcgctc cacagctcct ccagcagctg cctcatctga
     1861 ggctgccagc ttctccaagc cggatgccat ccagccaccc cttctcctgg tcccctcctt
     1921 gtgctgctgc catgctcctg ctaggtccct gcagagaaga ggatggtaga cctggagcaa
     1981 gcatgacctt gggtaccaga gggcaggcac cagagccagc atcctcttcc acttctcttc
     2041 cttttattct gaacttaacc aagatcttcc catgtggaac tgaatggcgg aaggcaaggg
     2101 ggcagggcct aggcacctag aagccagcac agttaccagg acatggccag atactgaagg
     2161 tgttgccagc tcggtaccca cctcccagtc cttacaggcc taagggagtc tggtataggc
     2221 ccctactgtg attcatttgt agattatggt tttctgcatt aaaacgtttg tttctggaaa
//
