LOCUS       NM_001033292            6499 bp    mRNA    linear   ROD 07-AUG-2024
DEFINITION  Mus musculus espin-like (Espnl), mRNA.
ACCESSION   NM_001033292 XM_149072
VERSION     NM_001033292.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6499)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6499)
  AUTHORS   Sundberg,J.P., Dadras,S.S., Silva,K.A., Kennedy,V.E., Garland,G.,
            Murray,S.A., Sundberg,B.A., Schofield,P.N. and Pratt,C.H.
  TITLE     Systematic screening for skin, hair, and nail abnormalities in a
            large-scale knockout mouse program
  JOURNAL   PLoS One 12 (7), e0180682 (2017)
   PUBMED   28700664
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6499)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   4  (bases 1 to 6499)
  AUTHORS   Ebrahim,S., Avenarius,M.R., Grati,M., Krey,J.F., Windsor,A.M.,
            Sousa,A.D., Ballesteros,A., Cui,R., Millis,B.A., Salles,F.T.,
            Baird,M.A., Davidson,M.W., Jones,S.M., Choi,D., Dong,L.,
            Raval,M.H., Yengo,C.M., Barr-Gillespie,P.G. and Kachar,B.
  TITLE     Stereocilia-staircase spacing is influenced by myosin III motors
            and their cargos espin-1 and espin-like
  JOURNAL   Nat Commun 7, 10833 (2016)
   PUBMED   26926603
  REMARK    Erratum:[Nat Commun. 2017 Aug 14;8:16133. doi: 10.1038/ncomms16133.
            PMID: 28805204]
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6499)
  AUTHORS   Lelli,A., Michel,V., Boutet de Monvel,J., Cortese,M.,
            Bosch-Grau,M., Aghaie,A., Perfettini,I., Dupont,T., Avan,P.,
            El-Amraoui,A. and Petit,C.
  TITLE     Class III myosins shape the auditory hair bundles by limiting
            microvilli and stereocilia growth
  JOURNAL   J Cell Biol 212 (2), 231-244 (2016)
   PUBMED   26754646
REFERENCE   6  (bases 1 to 6499)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC110510.6.
            
            On Oct 17, 2022 this sequence version replaced NM_001033292.3.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK134448.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-304               AC110510.6         87156-87459
            305-495             AC110510.6         88512-88702
            496-682             AC110510.6         90069-90255
            683-865             AC110510.6         92509-92691
            866-997             AC110510.6         99723-99854
            998-1112            AC110510.6         105542-105656
            1113-1210           AC110510.6         106879-106976
            1211-1405           AC110510.6         107574-107768
            1406-6499           AC110510.6         109348-114441
FEATURES             Location/Qualifiers
     source          1..6499
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 46.08 cM"
     gene            1..6499
                     /gene="Espnl"
                     /gene_synonym="Gm556"
                     /note="espin-like"
                     /db_xref="GeneID:227357"
                     /db_xref="MGI:MGI:2685402"
     exon            1..304
                     /gene="Espnl"
                     /gene_synonym="Gm556"
                     /inference="alignment:Splign:2.1.0"
     exon            305..495
                     /gene="Espnl"
                     /gene_synonym="Gm556"
                     /inference="alignment:Splign:2.1.0"
     exon            496..682
                     /gene="Espnl"
                     /gene_synonym="Gm556"
                     /inference="alignment:Splign:2.1.0"
     exon            683..865
                     /gene="Espnl"
                     /gene_synonym="Gm556"
                     /inference="alignment:Splign:2.1.0"
     exon            866..997
                     /gene="Espnl"
                     /gene_synonym="Gm556"
                     /inference="alignment:Splign:2.1.0"
     exon            998..1112
                     /gene="Espnl"
                     /gene_synonym="Gm556"
                     /inference="alignment:Splign:2.1.0"
     exon            1113..1210
                     /gene="Espnl"
                     /gene_synonym="Gm556"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1405
                     /gene="Espnl"
                     /gene_synonym="Gm556"
                     /inference="alignment:Splign:2.1.0"
     exon            1406..6499
                     /gene="Espnl"
                     /gene_synonym="Gm556"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5373..5378
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Espnl"
                     /gene_synonym="Gm556"
                     /note="hexamer: AATAAA"
     polyA_site      5397
                     /gene="Espnl"
                     /gene_synonym="Gm556"
                     /note="major polyA site"
     regulatory      6479..6484
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Espnl"
                     /gene_synonym="Gm556"
                     /note="hexamer: AATAAA"
     polyA_site      6499
                     /gene="Espnl"
                     /gene_synonym="Gm556"
                     /note="major polyA site"
ORIGIN      
        1 agacttgagg atggaggcgc agcaggcact ggtggcctcc aaggatgggg atatggccac
       61 cttggaacgg ctatttgagg ctggtgccct aagaccagac atcactgatg atctgggggc
      121 tggcctggtg catcatgcca cccgggctgg tcacctggac tgtgtcaagt tcctggtaca
      181 gagagccaag ctgccaggca accagcaggc acacaacggg gccacaccag tgcacgatgc
      241 agcagccacg ggcaacctgg cagagctgtg ctggctggtc cgtgatgcgg gctgcgggct
      301 gcaggaccaa gatgcctcag gtgtctctcc gctgcacctg gctgcccggt ttggacaccc
      361 agccctggtg gagtggttac tccgtgaggg ccatgcagcc acactggaga cgctggaagg
      421 ggccttacca ctgcaccacg ctgctgtaag tggtgatctg acctgtctga aactcctgac
      481 agcggcccac agcagtggtg tgaaccagcg gacatgcagt ggtgcctctc cactctacct
      541 ggcctgccaa gagggccacc tgcatctggc acagttcctg gtgaaagact gcggggccga
      601 cgtgcgcctg agagccctgg atggcatgag ctcattgcac gctgcggctg cccacggcca
      661 ctactctcta gttgtctggc tggtgacatt cacagacatc ggcctgacag cacgggataa
      721 tgaaggagcc actgccctgc actttgcagc tcgggggggc cacacaccta ttctcgaccg
      781 gctcctgctc atgggtgccc ccatcatgag agactcttgg ggagggactc ccctgcatga
      841 tgcagccgag aatggacaca tggagtgctg ccagactctg ctctcccacc acgtagaccc
      901 cttcctgcgg gatgaagatg ggtatacagc gatagacctg gcagagtacc atggacacca
      961 ggattgtgcc cagttcctgc gggaaatgtc tcggccggtg cgggtcctga tgacaccccc
     1021 acccccacca tttccacctc ctccactgct ggctgcaaaa ctctccctgg aagaggaaag
     1081 aagaggggac tcgggactca aaagcccctc atctgcaact ctcagcccag tctggcctgc
     1141 tcagcctgtc ccaagggaac cgatggcctg cacggcccct ctgagggtca ccaccccaga
     1201 tgctcttcag gggcctgagg tggaagcccg ggactcccgt gctggcctag ccactctgca
     1261 gctggatggc ttgcctgcgg gagatcttga catgctggtg cccacacagg acgagcgtgg
     1321 ccggcccatc cctgagtgga agcggcaggt gatggtgcgg aagctacagg ctcgcctggg
     1381 tgcagaccat cctccagaag accaggacca gagtcagagg caggactcag ggcccaccgc
     1441 tgcagaacag gcaacttgga gatattcaca gacgcaccag gccatcctgg gcccctttgg
     1501 agagctgctg acggaggatg atcttgtata cctggagaag cagatcaacg acctgcagct
     1561 ccggcgacgc tgccaggagt atgagagtga gttgggccgg ctggcagccc agctgcaggc
     1621 cctcctgccc gagcccctgg tcagcatcac cgtcaacagc cactttctgc cccgggctcc
     1681 cggcctggaa gacgaggaag ctccagtcct ggcgactgaa ctcgaagcct ccgaggagcc
     1741 ggggaaggcc gagcccagag ggcagccgct gcccttctgg tgcagccaca tcggtcgcct
     1801 ggtgcgcagc atgtccctgc tgctgaaggg tatgaacggg ctggcacagg gtgaggagaa
     1861 accaccctca ccggtcccgc aggacctagg caaggagacc attgccggcc cctcccggag
     1921 cgaggcccag cgcgagatcc aagagtgcgg agtgtcagtt cggacattgc gggggaactt
     1981 cgagtttgcc cctgatctgc cctgcgcctt gaactcgggt ccctgtgagc tgggggtgcg
     2041 gcctggccag tgtctgagag gttgctggtc ggcgccgcca cagccccgag gcgacgcgat
     2101 gggtggggag cccgggccag gcgacacaga ggaggccagc gactcgggca tcagctgcga
     2161 agaggccccg tcagaggccg gcgcgggtcc agggctggac ctggccagct tgcgcaagga
     2221 gcgcatcgtc atgctcttcc tcggccattg gaagaagtca gcctacacgc ccgcgctccg
     2281 gacggcagcc tgcaggaccc tggaggctca gcgtgcacga tccaggggcc cagaggccgc
     2341 gggtagcccc cggccgtcct ccccgcagcc cagcgatggc cctcggcttg gccacctgtg
     2401 gcagcagcgt ggcatcatca cccacctgct gggcacctgg aaagccatca tggcgcacgt
     2461 gcccgcccgg cagctgcgga ggctgagccg cagggagcgt gggcccctgt ctccggagca
     2521 gttcttgccg cacgtggacg gggcccccgt gccctacaac agcctctcgc tggacctctt
     2581 catgcttggc tacttccagc tcctggagtg cgacctgcca gccgaggagc gcaagatgcg
     2641 ccacctgctg tgcttcgagg ttttcgagca tctgggcgca cacggctggg aggctgtgcg
     2701 agccttccat aaggcagtga ccgacgaggt ggccgcgggt cgccgcgcct ggaccgacgg
     2761 ctttgaggac atcaaagccc gcttcttcgg ctccagccag ggtcccccct gggacgtgga
     2821 gccaggtcgc aagctgggcc tgacaccact cgggtccttg ccccatgctt cccttcctgg
     2881 cagcggccct gaacctgcgg tgccgccgag gctggggtct gattcccagg ggagcagctt
     2941 caacagcgga gacatctgtg gctacatcga ccgcagcttc gcattctgga aggagaaaga
     3001 ggctgagatg tttaactttg gagaatgact gttcacctgg tgcgatagga cgctgggggg
     3061 gggggggaga ggtttggggt tcctttgttc attctttgtg ctccccgggg gtcaggtgaa
     3121 gtgggctgac ttctgtctgt cttcatagag atcagaggtc tcttaggcct tggtgcccat
     3181 ctcttctgag cagtgactgg gatcaaatcc ttctcacttg tgagcacagc cctcagaccc
     3241 tcaagtggtc gtatgggtct gagggtcctg cagccaagga gctggttctg tttccagctg
     3301 tcacatgggt gtcagtttta atggctcagg tggtctcagc tacacggcca ccttctctac
     3361 acctcccttt gggcctcagc tctgggcctg cctctattgt ttgtttgttt gtttgttttc
     3421 tggcaacttc ctatctctaa aaccagaggg agctgtgtct agagtgacca atctccctga
     3481 caggagagct tctgagaccc caaagcctca aggcagacaa gtggccctgc cccgattctc
     3541 ctgctggtca gcatagctgc tatggtatga atgctagcag catctcttct ctggcactgc
     3601 ctggaccctg aaggaaagct ctctgttagg cctttgtctt ccagctgact aacccttcca
     3661 agaccctcag atggaggccg tggctgggcc acaggaggtc cctaagagca aggataccaa
     3721 gaggtgagga accctttgaa tagaaaggtt ggtatcctct ggagggaaac tggccttcag
     3781 aagctgggaa cagcttacag caaggggcaa acatagcagg ggtgttcatg tggacatctg
     3841 ggtgtcacct tcccacttgg gcacagagaa aggagttaaa caccttgggg attccaggta
     3901 ccatagagag ccacaggagc caggtgctag agagggatcc ctccccaccc ccagattgct
     3961 gactgtaaga tagagcttgt ttgattcccg cttctggtga cagacagaag gatgagtcac
     4021 cacccacctt atgggggcca ggagaactgg cctggaatcc atggaggact ttggggtagt
     4081 gactttttga ggagaataca actggcatgg gacagggatc tgcagtcaag tctcttaggg
     4141 gcaaagccat gcacagtggg gacaggccat ctccaagagt ctcctacagt gtccccgcat
     4201 taccactagg gggagcaggg agtcctaacc ttgggctctg ggatgacagt agaaaggcag
     4261 tctatacaga ctcaagacta tgtaagggtc ccatagacgg ggacctccag ggagataaag
     4321 ttggcacagg gcatgggttt tggtgctggg ggagccacaa agggcagtgg tacaggtcct
     4381 ggctccaagt tgcctccagc ctgggcccac ctgggacctg ctctgagatg gtggggtgaa
     4441 tcctcctttt ctgcctttgg cttcctctgc ctttagagtc tcatcagaag ctgaagctgg
     4501 atatatgttt gctaaataaa attgccacca caatacccac acaccagcaa aagcaagtgc
     4561 cccctcccag ccccggccct ctggtgtaag ctgcaccttt taaagatggt ggcacatttt
     4621 agtttggtga attcacactt ggagtctatt ctgggggaaa taactgcata gctgatcctc
     4681 ttcatcacag cacccaaaat ggaaagtgac ccgaaagccc gtgaatagga gctgtgcctg
     4741 gtgtcacctc cagccttggg aaggaaggta tcgccatgtc cagatgaaat ttaaacctgt
     4801 gttctcaaac caatctcctc aaagctcatg attcaccatc aagtgatcaa aacagtgact
     4861 tgggctcctc ccgcgtcacg cccagactca tggttgacag tctgtaaggg atattgttat
     4921 ttgctgctgg agagttcttc tttatacttt tcaaacccgt gtgtgtgatt tttttttttt
     4981 ccaaatcacc ctaggcctat tttaaaggtg cagcccttgg aagaaatctg tcattttgag
     5041 atcctagttg aaagggcaac agaaacccca tttgtctcca tttaaggacc aggcctgatt
     5101 ccgaaaagaa ggccataagc gccagctcca ggaacagcct aaggatacgc acaaaatggg
     5161 gaaatatctc agaatgagcc acctgtgctg ggcagcccta tctcatccta tggttaaaca
     5221 tgacatagaa atgcagacct ctaatcacct gtgacccact agcactcaca aaggaaattt
     5281 tagattaccc taccttttaa agtaacctac ctttatctag ggtaaccatt tcaaaaaatg
     5341 gttggccccc cgcatgctgg ttgtttctgc agaataaaca ctctttgttt ttgcatactc
     5401 tctgaggctg gggtcttcct tcagcaattt tcagaccctt atactagtgt tgtgtctcct
     5461 gcctggtctg tcatctgatg atgcaccgag cctctagtgc ccgcatggtc tgctggggac
     5521 ctgctcactt ggcacagcca gcactctctg tgacagagcc tgtgtcacca ttcctgtcct
     5581 tcactccctc tagacagagc agggaggcac tgaccctgca aatggggtgt taagcaaagc
     5641 cttcaccttg cttcagtatc tttcccctaa atgcctccca gacaaggaca cccatgaggg
     5701 tcccctatac cacatgaagt ttaatatcaa aaccggagag agcgtctcac tgtggccaag
     5761 aaacgaggga cgaaggagaa ggtcatggag gtgagtaagg agagaagcac agagcagggg
     5821 ccctgcacat ggcaggccct gcagggctct cctggggatg aacaagttct tcctgggaat
     5881 gaggctgtag tgagtgtctg ctacatgaat gtccccagct gctgtaccag acaggaagat
     5941 gtcatgtatc cagcactctg ccaggagggc tgtccctcag ggccacctgg gaccctgtct
     6001 gtgagaacat cacttccatc cctagtgccc tcccaaagca gcatacctat ggttattcta
     6061 catgtgagaa ggagggaggt actgatgata cggcctagcc tgctcaccca ggctgaggtg
     6121 tcccttctgt gcactgaggt atcctacctg tgcattaaag caccctgtac tggctggttt
     6181 tgtggtcaac ttaacacaag ctggagttat cacagagaaa ggaccctccc ttgaggaaat
     6241 gcctccatga gatccagctg taagatatta gtgatcaagg atgggaggga ccattgtggg
     6301 tggtactatc cctgggctgg tagtccttgg ttctataaga aagcaagctg agcaagccag
     6361 gggaaacaag ccagtaacat ccctctgtgg cccctgcatc agctcctgct tcctgacctg
     6421 cttgaattcc agttctgact tcctttggtg atgaacagca acatgaaagt gtatgctgaa
     6481 taaacacttt cctccccaa
//
