LOCUS       NM_026129               1258 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus endoplasmic reticulum protein 29 (Erp29), mRNA.
ACCESSION   NM_026129
VERSION     NM_026129.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1258)
  AUTHORS   Bose,A., Kasle,G., Jana,R., Maulik,M., Thomas,D., Mulchandani,V.,
            Mukherjee,P., Koval,M. and Das Sarma,J.
  TITLE     Regulatory role of endoplasmic reticulum resident chaperone protein
            ERp29 in anti-murine beta-coronavirus host cell response
  JOURNAL   J Biol Chem 299 (2), 102836 (2023)
   PUBMED   36572185
  REMARK    GeneRIF: Regulatory role of endoplasmic reticulum resident
            chaperone protein ERp29 in anti-murine beta-coronavirus host cell
            response.
REFERENCE   2  (bases 1 to 1258)
  AUTHORS   Zhang,Y., Hu,Y., Wang,J.L., Yao,H., Wang,H., Liang,L., Li,C.,
            Shi,H., Chen,Y., Fang,J.Y. and Xu,J.
  TITLE     Proteomic identification of ERP29 as a key chemoresistant factor
            activated by the aggregating p53 mutant Arg282Trp
  JOURNAL   Oncogene 36 (39), 5473-5483 (2017)
   PUBMED   28534505
  REMARK    GeneRIF: The anti-aggregation peptide ReACp53 significantly
            decreased ERP29 expression and suppressed the chemoresistant
            effect. These findings highlight a role of ERP29 in the acquired
            chemoresistance of cancer cells expressing the aggregating p53
            mutant Arg282Trp.
REFERENCE   3  (bases 1 to 1258)
  AUTHORS   Gao,J., Zhang,Y., Wang,L., Xia,L., Lu,M., Zhang,B., Chen,Y. and
            He,L.
  TITLE     Endoplasmic reticulum protein 29 is involved in endoplasmic
            reticulum stress in islet beta cells
  JOURNAL   Mol Med Rep 13 (1), 398-402 (2016)
   PUBMED   26548430
  REMARK    GeneRIF: Erp29 may have an important role in Endoplasmic reticulum
            stress in islet beta cells.
REFERENCE   4  (bases 1 to 1258)
  AUTHORS   Werber,M., Wittler,L., Timmermann,B., Grote,P. and Herrmann,B.G.
  TITLE     The tissue-specific transcriptomic landscape of the mid-gestational
            mouse embryo
  JOURNAL   Development 141 (11), 2325-2330 (2014)
   PUBMED   24803591
REFERENCE   5  (bases 1 to 1258)
  AUTHORS   Hirsch,I., Weiwad,M., Prell,E. and Ferrari,D.M.
  TITLE     ERp29 deficiency affects sensitivity to apoptosis via impairment of
            the ATF6-CHOP pathway of stress response
  JOURNAL   Apoptosis 19 (5), 801-815 (2014)
   PUBMED   24370996
  REMARK    GeneRIF: ERp29 acts as an escort factor for ATF6 and promotes its
            transport from ER to Golgi apparatus under ER stress conditions.
REFERENCE   6  (bases 1 to 1258)
  AUTHORS   Sargsyan,E., Baryshev,M., Backlund,M., Sharipo,A. and Mkrtchian,S.
  TITLE     Genomic organization and promoter characterization of the gene
            encoding a putative endoplasmic reticulum chaperone, ERp29
  JOURNAL   Gene 285 (1-2), 127-139 (2002)
   PUBMED   12039039
REFERENCE   7  (bases 1 to 1258)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   8  (bases 1 to 1258)
  AUTHORS   Hubbard,M.J. and McHugh,N.J.
  TITLE     Human ERp29: isolation, primary structural characterisation and
            two-dimensional gel mapping
  JOURNAL   Electrophoresis 21 (17), 3785-3796 (2000)
   PUBMED   11271497
REFERENCE   9  (bases 1 to 1258)
  AUTHORS   Ferrari,D.M. and Soling,H.D.
  TITLE     The protein disulphide-isomerase family: unravelling a string of
            folds
  JOURNAL   Biochem J 339 (Pt 1) (Pt 1), 1-10 (1999)
   PUBMED   10085220
  REMARK    Review article
REFERENCE   10 (bases 1 to 1258)
  AUTHORS   Demmer,J., Zhou,C. and Hubbard,M.J.
  TITLE     Molecular cloning of ERp29, a novel and widely expressed resident
            of the endoplasmic reticulum
  JOURNAL   FEBS Lett 402 (2-3), 145-150 (1997)
   PUBMED   9037184
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC017125.1.
            
            On Jun 19, 2003 this sequence version replaced NM_026129.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC017125.1, AK168112.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386, SAMN00849389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1258
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 61.8 cM"
     gene            1..1258
                     /gene="Erp29"
                     /gene_synonym="1200015M03Rik; 2810446M09Rik; Erp28; Erp31;
                     PDI-Db"
                     /note="endoplasmic reticulum protein 29"
                     /db_xref="GeneID:67397"
                     /db_xref="MGI:MGI:1914647"
     exon            1..284
                     /gene="Erp29"
                     /gene_synonym="1200015M03Rik; 2810446M09Rik; Erp28; Erp31;
                     PDI-Db"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..923
                     /gene="Erp29"
                     /gene_synonym="1200015M03Rik; 2810446M09Rik; Erp28; Erp31;
                     PDI-Db"
                     /note="endoplasmic reticulum resident protein 29"
                     /codon_start=1
                     /product="endoplasmic reticulum resident protein 29
                     precursor"
                     /protein_id="NP_080405.1"
                     /db_xref="CCDS:CCDS19634.1"
                     /db_xref="GeneID:67397"
                     /db_xref="MGI:MGI:1914647"
                     /translation="MAAAAGVSGAASLSPLLSVLLGLLLLFAPHGGSGLHTKGALPLD
                     TVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSEELLVAEVGISDYGDKL
                     NMELSEKYKLDKESYPVFYLFRDGDLENPVLYNGAVKVGAIQRWLKGQGVYLGMPGCL
                     PAYDALAGEFIKASSIEARQAILKQGQDGLLSVKETEKKWASQYLKIMGKILDQGEDF
                     PASEMARIGKLIENKMSDSKKEELQKSLNILTAFRKKEAEKEEL"
     exon            285..423
                     /gene="Erp29"
                     /gene_synonym="1200015M03Rik; 2810446M09Rik; Erp28; Erp31;
                     PDI-Db"
                     /inference="alignment:Splign:2.1.0"
     exon            424..1243
                     /gene="Erp29"
                     /gene_synonym="1200015M03Rik; 2810446M09Rik; Erp28; Erp31;
                     PDI-Db"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1222..1227
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Erp29"
                     /gene_synonym="1200015M03Rik; 2810446M09Rik; Erp28; Erp31;
                     PDI-Db"
                     /note="hexamer: AATAAA"
     polyA_site      1243
                     /gene="Erp29"
                     /gene_synonym="1200015M03Rik; 2810446M09Rik; Erp28; Erp31;
                     PDI-Db"
                     /note="major polyA site"
ORIGIN      
        1 gcatctcgct ctggcggtgg ccgcttgcgt tcatgcgcgc cgccggcagg acggccctcc
       61 ccgtgacgtg accgcccact cggagcgctc cgcctgtagc ttgcctgtct ctcccgctcc
      121 caccatccgg cgtgatggcc gccgccgccg gggtgtctgg cgctgcttct ctctccccac
      181 tgctgtccgt gctcctgggc ctgctgctcc tctttgctcc gcacggcggc agcggcctac
      241 acacgaaggg tgcccttccc ttggacacag tcactttcta caaggtcatt cccaaaagca
      301 agttcgtctt ggtgaagttc gacacccagt acccctatgg agagaagcaa gatgagttca
      361 agcgtctggc tgagaactca gcctccagcg aggagctctt ggtggcagag gtggggatct
      421 cagactatgg cgacaagctg aacatggagc tgagtgagaa gtacaagctg gacaaggaga
      481 gctacccagt cttctaccta ttccgggatg gggacttgga gaaccctgtg ctgtacaatg
      541 gggcagttaa ggttggagcc atccagcgct ggctaaaggg gcagggggtc tacctgggca
      601 tgcctgggtg cctgcctgca tacgatgccc tggcaggcga gttcatcaag gcctccagca
      661 tagaggcccg acaggccatc ttgaaacagg gacaggatgg cctcctaagt gtgaaggaaa
      721 cagagaagaa gtgggctagc caatacctga agatcatggg gaagatcctg gaccaaggtg
      781 aggactttcc agcctctgag atggcccgga tcggtaagct gatagagaac aagatgagtg
      841 acagcaagaa agaagagcta cagaagagct taaacatcct gacggccttc cggaagaagg
      901 aggctgagaa ggaggagctg tgaccaagca caagggttcc ccagggtttg ccaggggcag
      961 gaaaggagag atctacctgc cagctgtggg acccctgtgg gtggaagggg cagtggagca
     1021 atgcaggcct gagccagaag tctgtgcccc gagtgtgcct ggacattgat gctgctgaga
     1081 tcatacttag gacaccccct gagccagtct gtggagagcc tgtgtgctca gtcaagatgg
     1141 ctggtgagat gccccccgca ggagttggtg ctatagaggt agggactact gccaggtcct
     1201 tgatgagtgt aattctgatc aaataaaaag tctgttttgg ttaaaaaaaa aaaaaaaa
//
