LOCUS       NM_001081213            5396 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus endoplasmic reticulum metallopeptidase 1 (Ermp1),
            transcript variant 1, mRNA.
ACCESSION   NM_001081213 NM_146098 XM_358328
VERSION     NM_001081213.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5396)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5396)
  AUTHORS   Garcia-Rudaz,C., Luna,F., Tapia,V., Kerr,B., Colgin,L., Galimi,F.,
            Dissen,G.A., Rawlings,N.D. and Ojeda,S.R.
  TITLE     Fxna, a novel gene differentially expressed in the rat ovary at the
            time of folliculogenesis, is required for normal ovarian
            histogenesis
  JOURNAL   Development 134 (5), 945-957 (2007)
   PUBMED   17267443
  REMARK    GeneRIF: Functional analysis of the rat Fxna ortholog.
REFERENCE   3  (bases 1 to 5396)
  AUTHORS   Chiellini,C., Costa,M., Novelli,S.E., Amri,E.Z., Benzi,L.,
            Bertacca,A., Cohen,P., Del Prato,S., Friedman,J.M. and Maffei,M.
  TITLE     Identification of cathepsin K as a novel marker of adiposity in
            white adipose tissue
  JOURNAL   J Cell Physiol 195 (2), 309-321 (2003)
   PUBMED   12652657
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC114578.14.
            
            On or before Apr 6, 2018 this sequence version replaced
            NM_146098.1, NM_001081213.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK129447.1, AK050284.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164133 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-380               AC114578.14        135501-135880       c
            381-682             AC114578.14        133432-133733       c
            683-810             AC114578.14        127322-127449       c
            811-916             AC114578.14        124756-124861       c
            917-1063            AC114578.14        119856-120002       c
            1064-1156           AC114578.14        118808-118900       c
            1157-1369           AC114578.14        116069-116281       c
            1370-1590           AC114578.14        114312-114532       c
            1591-1765           AC114578.14        111106-111280       c
            1766-1956           AC114578.14        110534-110724       c
            1957-2109           AC114578.14        105283-105435       c
            2110-2312           AC114578.14        103982-104184       c
            2313-2428           AC114578.14        103188-103303       c
            2429-2592           AC114578.14        100234-100397       c
            2593-5396           AC114578.14        97341-100144        c
FEATURES             Location/Qualifiers
     source          1..5396
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 24.17 cM"
     gene            1..5396
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /note="endoplasmic reticulum metallopeptidase 1"
                     /db_xref="GeneID:226090"
                     /db_xref="MGI:MGI:106250"
     exon            1..380
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /inference="alignment:Splign:2.1.0"
     exon            381..682
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /inference="alignment:Splign:2.1.0"
     exon            683..810
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /inference="alignment:Splign:2.1.0"
     exon            811..916
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1063
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /inference="alignment:Splign:2.1.0"
     exon            1064..1156
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1369
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /inference="alignment:Splign:2.1.0"
     exon            1370..1590
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /inference="alignment:Splign:2.1.0"
     exon            1591..1765
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /inference="alignment:Splign:2.1.0"
     exon            1766..1956
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /inference="alignment:Splign:2.1.0"
     exon            1957..2109
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /inference="alignment:Splign:2.1.0"
     exon            2110..2312
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /inference="alignment:Splign:2.1.0"
     exon            2313..2428
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /inference="alignment:Splign:2.1.0"
     exon            2429..2592
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /inference="alignment:Splign:2.1.0"
     exon            2593..5396
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5053..5058
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /note="hexamer: AATAAA"
     polyA_site      5084
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /note="major polyA site"
     regulatory      5369..5374
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /note="hexamer: AATAAA"
     polyA_site      5392
                     /gene="Ermp1"
                     /gene_synonym="b2b2633Clo; D19Ertd410e; D19Wsu12e; Fxna;
                     mKIAA1815"
                     /note="major polyA site"
ORIGIN      
        1 ggaggccgcg gtggcccgga ctgtcgcagg ctggggcggt tggtggtggc agttgccgcc
       61 atggagtgga gctcggagtc agcggctgtg cggcggcacc gcggcaccgc ggagcgtcgg
      121 gagggagagg cggccgcgtc gcaccggcag agagaggcct cagcgcagga ggatgcgaag
      181 ggcgtcggga ggatgtgggg gaagacggag aacggcggcg ggagccgggt tgcgaagacc
      241 gcgctgtccg aggcgcgcac ggcgctggcg ctcgcactct acctgctcgc gctgcgggcg
      301 ctcgtgcagc tctcgctgca gcggctggtg ctgagccgga cctcggggct ccagggcgag
      361 ttcgacgcgc gccaagccag ggattatctg gaacacataa cggccattgg ccccaggact
      421 acaggaagca cagaaaatga aattctgacg gtacagtacc ttttggagca gatcaagctg
      481 atagaagcac aaagcaacag ccttcacagc atctccgtag atatacagcg gcccaccggt
      541 tcctttagca ttgacttctt ggggggcttc acgagctact atgacaacat tactaatgtc
      601 gtggtaaagc tggagccccg ggatggagcc gagtctgcta tcctggctaa ctgtcacttt
      661 gactcagtgg caaattcacc aggtgccagt gacgatgcag ttagctgtgc agtgatgctc
      721 gaagttctcc gggtcatgtc agcgtctcca gagcccatgc agcacgctgt ggtgttcctc
      781 tttaatggcg cagaggaaaa tgtcttgcaa gcaagccatg gttttattac tcaacatccc
      841 tgggccagtt tgattcgagc atttattaac ctggaggctg ctggtgtcgg agggaaagaa
      901 cttgtgttcc aaacaggccc tgaaaatcct tggttggtcc aggcttacgt ttcggcagct
      961 aaacaccctt ttgcctctgt ggtggctcag gaggttttcc agagtgggat cattccctct
     1021 gacaccgact tcagaatcta cagggatttt gggaacattc caggaataga cttagctttt
     1081 attgaaaatg gatacatcta tcacaccaag tatgacacag cggacaggat tctcatagat
     1141 tccattcaga gagcaggtga caacatttta gcagttctta aacacctggc tacgtctgac
     1201 accctggctt cttcgtctga gtaccggcat gggagcatgg tgttcttcga tgtgctcggc
     1261 ctgctggtca ttgcgtaccc ttctcgtgtc ggctccataa tcaactacat ggtggtcatg
     1321 gccgtggttc tgtacctggg gaagaaactt ctgcggccca agcacaggaa tgctaattac
     1381 atgagagact tcttgtgtgg actcgggatc acattcatta gctggttcac tagccttgtt
     1441 accgtcctca ttatagcagt gttcatctct ctcattggac agtctctctc atggtataac
     1501 tacttttata ttgccgtttg cctgtatgga actgcaacag tcgccaaaat catattcatt
     1561 catactcttg caaaaagatt ttattatatg aatgccagcg acctgtatct gggagaactg
     1621 ttcttcgaca cctccctgtt cgtgcactgt gcttttcttg ttgctttaac ttatcaaggg
     1681 ttttgctctg cattcatgag tgccgtctgg gtagtttttc cattgctcac aaagctttgt
     1741 gtgtacaagg acttcaagaa gcacggtgcc caaggaagat ttgttgctct gtaccttttg
     1801 gggatgttta tcccatatct ttacgggctc tacctcatct gggctgtgtt tgagatgttc
     1861 actcctatcc tgggaagaag cgggtcggag atcccccccg acgttgtgct ggcctccatc
     1921 ctggctgtct gtgtgatgat cctctcttcc tattttatta ccttcatcta ccttgtgaac
     1981 agcacaaaga aaaccattct gactctaata ctggtgtgcg cggtcacctt cctccttgtc
     2041 tgcagtggag cctttttccc atatagttct aatcccgaga gtccaaagcc aaagagagtg
     2101 tttcttcagc acgtgagtag aacttttcat aacttagaag gaagcgtagt aaaaagagac
     2161 tctggaatat ggatcaatgg gtttgattat actggaatgt ctcacgtaac acctcacatt
     2221 cctgagatca acgacacaat ccgagctcac tgtgaggagg atgccccact ctgtggcttc
     2281 ccttggtatc ttccagtgca cttcctgatc aggaaaaact ggtatcttcc agctcccgag
     2341 gtctctccaa gaaaccctgc tcatttcaga cttgtgtcca aagagaaaat gccatgggat
     2401 tcgataaagt tgacctttga agcaacagga ccaagccata tgtctttcta tgttcgaacc
     2461 cacaaaggat caacactttc ccagtggtct cttggcaacg gcatcccagt cacaagcaga
     2521 ggaggagact actttgtgtt ttattcccat ggactccagg cttctgcatg gcggttctgg
     2581 atagaagtgc aggtctcaga agaacaggca gaaggaatgg tgactgtggc cattgctgcc
     2641 cactatctat caggggagaa caaaagatcc tctcagctgg atgctctgaa gaagaagttc
     2701 ccagactggt cctttccttc ggcgtgggtt tccacctaca gtctctttgt gttttaatct
     2761 cgcggatgga ctttgagtac atgtcccctg aacattgcat gggatagttt ctctcccatg
     2821 atacaaggat gtttgtaata caagtcaatg aactctactg agcatatgtt caaagagctt
     2881 ttgggataac actcttcagg gctaagtact gtatgggtta aacttgggga cagtgatacc
     2941 tggccatgcc ggttgaaact tcctgttttc tgacaactaa gcacatgtgg atattgccaa
     3001 tcatgtcact catgactaag gactcagcag catgcctctt gagcagcttt cctgtgagga
     3061 tcaagaaaga tgtaggctct tagaccactg ctaatgaaat aggcaagtcc acttgccagt
     3121 ggaggtgggt aagatgcctc tctgtgcgct acaactgtag tactgggaag taaatgccac
     3181 aaaggtggaa gccgctgcag caccttagat gttcgagcgc tgtttcttca ggcagccgtt
     3241 cagatttttt ttgtctgttt ggaagcctaa gccctgatgc agaggcctga ctcctgagta
     3301 gcattcagtg tctgcttttc cctcaaacac attcctgtca tttacctggg gaagagaaca
     3361 tttttttcag ctacattttc ttcttacatt tcatgggttg ctttatttgt gcaagcacag
     3421 aacttaaaac ttcttcccca gagcactgaa ttgccagcat agctgctgag gtggaagagg
     3481 aggagggctg ggaggactgg ggattttata atatttattc tgttatatat aagattaatc
     3541 ctttagcaca agttctttat tgctgcattg ggttttctgt tttctagcag gtgactaagt
     3601 tgttgtaact tgccgtcagt gagaaccggc tgtcctgatg ttgaggttgt agcttacaca
     3661 ggagacaact atacctgtat ttgttaattt ttagatcccg cataagggca gcagtcagac
     3721 ttaatggtgc ttttcatttt gaagacaggg atgtagcttg tgaggtatgt cacggcagtg
     3781 gctcttgtgg cgtctctagg ttccatcagt gacagaggat gagatgaaca gtaaattatt
     3841 ctaattttac agtagtaaat atacaaagac aaaatttgag ttagctaaca agcatgacac
     3901 aaaatgtagt tgaaagaaaa gccatagtaa ggcaaaacca aaccaaacca aaccaaacaa
     3961 tatccttgtc aggtgagaac aggaaggcgc ctctcagagt ggccctcaga actgtctgaa
     4021 tgtcaacaag agcactgtta cgtgtgcacc gcagaagagg agcctctgga aattgctcgt
     4081 gtggtacgtg tcagtttctt aatcgtgttc cttgtattgc ctgcctaatc tataacgcct
     4141 taaaaacgct gcggctggag ctgatagtaa catgctgact gtcacaagtg gtgacactta
     4201 aagtggagtc agtgttttgc tggactcaca gaaatcttat ctcactagtg cttcaagtgt
     4261 ctggctcctg ctgtgtgtgt attctctgtc aggtcgtact taaagggttg agggtttatg
     4321 tctagcttgt agagaaccac agctgagtaa cagtactgat agctcaatga atttcaaaat
     4381 acgggcttat gttctgtgcc cgggttaatc tgaaactgat tactagaaat tatgggggag
     4441 gagagcaaca tgtcatgctg aggaagttca ctaggacaag gatgctctct gacttccttc
     4501 cctttggcag gcaccttttc agtgtaatca atcatggttt tctttctgtc tttgggttgt
     4561 ttctctatgc aaacgatttt cattttctct aacactatta tgcaaccact aacaagatgt
     4621 tcagtttcag gcatgcttaa cggccagaaa tggtcaggca attacatgca gtattcatgg
     4681 cttttaaaaa gcacactctg tagttatcac tagcctccta cctttaaagg ttatctgatc
     4741 acttgtgtaa ttcacttctc aaaagatagt ttcaaggtct aagtaatgca tcccccagaa
     4801 gagtataaac agaagcagca cactagggac aagtatgaag aactgaaaga ttgttctaca
     4861 cagcgtttcc agcttagcag ctataactaa atgtctgaga tttcccccaa ccctgatttt
     4921 gctgtgaaag agattagacc acaagccagc ctaggtgact caggaagctg ttggaagaac
     4981 atgtctgtcc atctcatttt cacttatttg ctgacttgtt gagggttaat cgttgcctta
     5041 caatgttact gaaataaact ttttaacaca ctggttggaa aaaatggatc ttttacaact
     5101 gctttttatt ctatctccat attttaaggc tattttttat ccctagtgtc tgtctgtctc
     5161 cgtctctctc tctctctctc tctctctctc tctctctctc tctctctcgt gtgtgtgtgt
     5221 gtgtgtgtac tatctttaaa atgctctata tagcttgaga attactgcta ttttaataag
     5281 tggtataagc aaagaactcg atagaaatgg tcacttcatc tggaatcttt tttccctgga
     5341 atgaaactgt gcatctgaat ttcagagaaa taaaaagaac ctgtttagca aatggg
//
