LOCUS       NM_001405474            2596 bp    mRNA    linear   ROD 14-AUG-2022
DEFINITION  Mus musculus ER membrane associated RNA degradation (Ermard),
            transcript variant 6, mRNA.
ACCESSION   NM_001405474 XM_006524459
VERSION     NM_001405474.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2596)
  AUTHORS   Harrow JL, Steward CA, Frankish A, Gilbert JG, Gonzalez JM,
            Loveland JE, Mudge J, Sheppard D, Thomas M, Trevanion S and Wilming
            LG.
  TITLE     The Vertebrate Genome Annotation browser 10 years on
  JOURNAL   Nucleic Acids Res 42 (Database issue), D771-D779 (2014)
   PUBMED   24316575
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC182749.2.
            
            [WARNING] On Apr 13, 2023 this sequence was replaced by
            NM_001405474.2.
            
            On Apr 25, 2022 this sequence version replaced XM_006524459.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422597.1013300.1,
                                           SRR13422598.318484.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-96                AC182749.2         163200-163295
            97-265              AC182749.2         163897-164065
            266-405             AC182749.2         164654-164793
            406-507             AC182749.2         165972-166073
            508-597             AC182749.2         166696-166785
            598-695             AC182749.2         169214-169311
            696-832             AC182749.2         170169-170305
            833-947             AC182749.2         171113-171227
            948-1050            AC182749.2         171920-172022
            1051-1080           AC182749.2         172396-172425
            1081-1149           AC182749.2         173220-173288
            1150-1323           AC182749.2         174863-175036
            1324-1407           AC182749.2         178400-178483
            1408-1484           AC182749.2         180409-180485
            1485-1610           AC182749.2         180993-181118
            1611-1829           AC182749.2         181415-181633
            1830-1943           AC182749.2         182718-182831
            1944-2596           AC182749.2         185229-185881
FEATURES             Location/Qualifiers
     source          1..2596
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17"
     gene            1..2596
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /note="ER membrane associated RNA degradation"
                     /db_xref="GeneID:381062"
                     /db_xref="MGI:MGI:1917317"
     exon            1..96
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..2130
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /note="isoform 6 is encoded by transcript variant 6"
                     /codon_start=1
                     /product="ER membrane associated RNA degradation isoform
                     6"
                     /protein_id="NP_001392403.1"
                     /db_xref="GeneID:381062"
                     /db_xref="MGI:MGI:1917317"
                     /translation="MEILPGDSMTTCLSPLVHDLICNLGFELKEICDINSIVTQNGEV
                     RWKAITDRVRYEELGRSLDYRRSVQQLGPVCEAIHLHISALTRAQFEIQYSPWYQWTT
                     YPELFLEILDALQSSQPAAVSLGVMKLASCLERALGDVFLLVGKECPFLLRDLLASAE
                     LAQVFGHAVMDILKVFIGSPCGLNLRNVLWHGFASPQDIPPKYCSAMLLLTAGLGQLL
                     KSYLHHTKVTLAHRPFVTLTNLEDVIVFPGVTYEVLSALETVMTKSNFLLKIMLPYWE
                     MAVSKFKSHRFADCTMLLLSQLEAGLRRLFAAVNKCPDRLLTAESTILYTTFDEILAK
                     HMSDGSMNQLPCFLGEPAMEFLWDFLNYQEGPRIRDRISHGEINIREFPEEAAGQLLT
                     FSLVLLLRFTEKGTVSELKEEAAIQLLVRLAEGYRSRCHPAFQLQKQVLSCERSLRMW
                     PVPPLPEECCQEAGRLEGNSEACACNSLISKIWCELCHYLPGSACAINGLDGLPSEKW
                     SQLLSELCSTRIPTLFCPRIVLEVLVVLRGINSQCQRVSDQVTASLQLRHRQWVERRL
                     RSRQRQNYVRMLSSVRLLCPMLSLILLLLALELASVHAVRDKGAEEQQQYLRFLKLVL
                     QYTENLVAYTSREKNKWSEATTLTHAVLLRIWTFSEKKQMLIHLAKKTTNKVDIS"
     exon            97..265
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            266..405
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            406..507
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            508..597
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            598..695
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            696..832
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            833..947
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            948..1050
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1051..1080
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..1149
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1150..1323
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1324..1407
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1408..1484
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1485..1610
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1611..1829
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1830..1943
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1944..2596
                     /gene="Ermard"
                     /gene_synonym="2210404J11Rik; 2410011O22Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acgtgagtca tcagagggcg ccgcatcccg gaagccggga aggaggggcg cgtgagtaat
       61 cagagagcgc cgcgacccga gccggaagcg atggagattt taccagggga ttccatgacc
      121 acatgccttt ctcctttagt gcatgacttg atttgtaacc ttgggtttga actcaaagaa
      181 atttgtgata tcaatagcat tgtaactcaa aatggtgaag tacgatggaa agcaattact
      241 gaccgtgtga gatatgaaga attagggcga agtctggact acaggagaag tgtgcagcag
      301 ctgggtccgg tgtgtgaggc catccaccta cacatctcag ctctgaccag ggctcagttt
      361 gaaattcagt attcgccttg gtaccagtgg acaacttatc cagagttgtt tcttgagata
      421 cttgatgcct tgcaaagctc gcagcctgct gccgtctccc tcggcgtgat gaaactagct
      481 tcctgtctgg agcgagccct cggcgacgta tttttactgg ttgggaaaga gtgccccttt
      541 ctcctaagag atcttcttgc atctgcagag cttgcacaag tctttggaca tgctgtgatg
      601 gacatactaa aagtcttcat cgggtctccc tgcggactca acctgagaaa cgtcttgtgg
      661 catggctttg cttcccctca agatattcct ccaaaatact gttcagccat gttgctgttg
      721 acggcaggac tgggccagtt actgaagagt taccttcacc acacaaaggt caccttggca
      781 catcgacctt ttgtaacact cacaaactta gaggatgtga ttgtttttcc tggtgtgact
      841 tatgaggtac tgtcagcatt agagacagtg atgacaaaat ccaacttcct attaaaaatc
      901 atgttgccat attgggaaat ggcagtgagc aagttcaagt cgcacaggtt tgccgactgc
      961 accatgttgt tgctgtcaca gctagaagct ggactcagga gactgtttgc tgcagttaac
     1021 aagtgtcctg atagactgct cacagccgag tcaacaattc tgtataccac gtttgatgaa
     1081 atactggcaa aacacatgag tgatggtagc atgaaccagc ttccttgttt ccttggagag
     1141 cctgccatgg aattcttgtg ggatttcctg aactatcagg agggtcctcg tatccgggat
     1201 cgtataagcc atggggagat caacatacgt gaatttccag aagaggccgc aggccagctg
     1261 ctcacattct ccctggtgct gctgctcaga ttcactgaga aggggacagt gtcagaactg
     1321 aaggaggaag cagcaataca gttgctggtt aggcttgcag aaggatacag gtctcgctgc
     1381 cacccagcct tccagcttca aaaacaggtg ctgagctgtg agagaagcct caggatgtgg
     1441 cctgtgccgc ctttgccaga agagtgttgt caggaagcag gcagattgga aggaaattct
     1501 gaagcatgtg cctgcaactc tttaattagc aagatttggt gtgagctctg ccactacctg
     1561 cctgggagtg cctgtgctat aaatggcttg gatggtcttc cctcagagaa gtggtcccag
     1621 ctgctcagtg aactgtgtag cacacgcatt cctacactgt tctgccccag aatcgttcta
     1681 gaagttctag ttgtgctccg aggcatcaac tcccagtgcc aacgcgtatc tgaccaggtc
     1741 accgcctctt tgcagctaag acacaggcaa tgggtggagc gtaggttacg ttcaaggcag
     1801 cgtcagaact atgtgcgcat gctcagcagt gttagacttt tatgtcccat gctttccctg
     1861 attttgttgc tccttgcact ggagttggcc agtgtccatg ctgttcgtga taagggcgct
     1921 gaggaacaac agcagtatct gagattctta aaattggtcc tacagtacac tgagaaccta
     1981 gtggcctaca ccagccgaga gaagaacaag tggagtgaag ccaccactct tacacacgca
     2041 gttttgttga ggatttggac tttcagtgag aagaaacaaa tgttaataca tttagccaaa
     2101 aaaaccacaa ataaagttga cataagctga caaagaaatc acgaatcaag gtatttttgg
     2161 tcgtgacact gagctataga ggagaccttg gtggtacttg gtggcagctg cacatcctgt
     2221 ctgtcccatt gcattttacc gtcaccccag cacacagcca acctctggaa gaacgtaaaa
     2281 atacaaagtt gcggttcatc acttgggatt taattgttcc ctcagattta acaccttatc
     2341 ttttaaagga acaatatcta catggtgcca tgtcttcaat gagtcacata aaggatacat
     2401 ggtccacaga catgctctgc atcacttcta ggtcatctgg ctctcatgca taatgacctg
     2461 tccttgtgtg tcacatcagc aacacaaggt cctgtatcct ggaccatttc atcatattgc
     2521 atcatttcaa gggagtggaa cccacctctg aatctgcttt gttaattaaa tgatttttaa
     2581 aaatgtttac catgaa
//
