LOCUS       NM_025745               3501 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus endoplasmic reticulum lectin 1 (Erlec1), mRNA.
ACCESSION   NM_025745
VERSION     NM_025745.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3501)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3501)
  AUTHORS   Cruciat,C.M., Hassler,C. and Niehrs,C.
  TITLE     The MRH protein Erlectin is a member of the endoplasmic reticulum
            synexpression group and functions in N-glycan recognition
  JOURNAL   J Biol Chem 281 (18), 12986-12993 (2006)
   PUBMED   16531414
  REMARK    GeneRIF: Erlectin functions in N-glycan recognition in the
            endoplasmic reticulum and may regulate glycoprotein traffic
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK133874.1 and AL662891.9.
            
            On Sep 8, 2006 this sequence version replaced NM_025745.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660811.14275.1, AK133874.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2511              AK133874.1         2-2512
            2512-3501           AL662891.9         168192-169181       c
FEATURES             Location/Qualifiers
     source          1..3501
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 18.18 cM"
     gene            1..3501
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /note="endoplasmic reticulum lectin 1"
                     /db_xref="GeneID:66753"
                     /db_xref="MGI:MGI:1914003"
     exon            1..218
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..1508
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /note="erlectin; ER lectin"
                     /codon_start=1
                     /product="endoplasmic reticulum lectin 1 precursor"
                     /protein_id="NP_080021.3"
                     /db_xref="CCDS:CCDS24509.1"
                     /db_xref="GeneID:66753"
                     /db_xref="MGI:MGI:1914003"
                     /translation="MEEGDGGLRSLVPGGPLLLVLYGLLEASGGGRALPQLSDDIPFR
                     VNWPGTEFSLPTTGVLYKEDNYIIMTTAHKEKYKCILPLVTSGDEEEEKDYKGPNPRE
                     LLEPLFKQSSCSYRIESYWTYEVCHGKHIRQYHEEKETGQKVNIHEYYLGNMLAKNLL
                     YEKEREAKENEKSNEIPTKNIEGQMTPYYPVGMGNGTPCSLKQNRPRSSTVMYICHPE
                     SKHEILSVAEVTTCEYEVVILTPLLCSHPKYKFRASPVNDIFCQSLPGSPFKPLTLRQ
                     LEQQEEILRVPFRRNKEEDLPSAKEERFPAIHKPIAVGSQPVLTVGTTHISKLTDDQL
                     IKEFLSGSYCFHGGVGWWKYEFCYGKHVHQYHEDKDNGKTSVVVGTWNQEEHVEWAKK
                     NTARAYHLQDDGTQTVRMVSHFYGNGDICDITDKPRQVTVKLKCKESDSPHAVTVYML
                     EPHSCQYILGVESPVICKILDTADENGLLSLPN"
     exon            219..323
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            324..404
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            405..482
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            483..546
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            547..581
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            582..805
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            806..935
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1097
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1098..1157
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1282
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1283..1360
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1436
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1437..3501
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1665..1670
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /note="hexamer: GATAAA"
     polyA_site      1683
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /note="major polyA site"
     regulatory      1853..1858
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /note="hexamer: ATTACA"
     polyA_site      1876
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
     regulatory      2299..2304
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2331
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
     regulatory      2495..2500
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2520
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
     regulatory      2654..2659
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2673
                     /gene="Erlec1"
                     /gene_synonym="4933407N01Rik"
ORIGIN      
        1 ctcctcctgt tctcctctgg tagaggaggt tgtgacggtg gctggaggac gcggcaatgg
       61 aggaaggaga cggcggcttg cggagcctgg tccccggagg gccactgttg ctggttctgt
      121 acggtctcct ggaggcgtcc ggcggcggcc gagcgctgcc ccagctcagc gacgacatcc
      181 ccttccgagt caactggcct ggtaccgagt tctctctgcc tacaactgga gttttgtata
      241 aagaagataa ttacatcatc atgacaactg ctcataaaga aaaatacaaa tgtatacttc
      301 cacttgtgac aagtggggat gaggaagaag aaaaggatta caaaggcccc aatccaagag
      361 agcttttgga accactattt aaacaaagca gttgttccta cagaattgaa tcttactgga
      421 cttatgaggt ctgtcatggg aaacatattc gacagtacca tgaagaaaaa gaaactggcc
      481 aaaaagtaaa tattcatgaa tactaccttg ggaatatgtt ggctaagaat cttctgtatg
      541 aaaaagaacg agaagcaaaa gaaaatgaaa agtcaaatga gattcccact aaaaacattg
      601 aaggtcagat gacaccctac tatcctgttg gaatgggaaa tggtacacct tgtagtctga
      661 aacaaaatcg acccagatca agtactgtga tgtacatatg ccatcctgaa tctaagcatg
      721 agatcctttc agtagctgaa gttacaactt gtgaatatga agttgtcatt ttgacaccac
      781 tcttgtgcag tcatcctaaa tacaagttca gagcctctcc tgtgaatgac atattctgtc
      841 aatcactgcc gggctctcca tttaaacccc tcacactaag acagttggag cagcaggaag
      901 agatactgag agtgccattc aggagaaata aagaggaaga tttgccatct gctaaggaag
      961 agagatttcc agccatccac aaacctattg ctgttggctc tcagccagtg ctcactgttg
     1021 gaacaaccca catttccaag ctgacagatg accagctcat caaggagttc ctaagtggct
     1081 cttactgctt tcatgggggt gttggttggt ggaaatatga attctgctat ggcaaacatg
     1141 tacatcaata tcacgaggac aaagataatg gaaaaacttc tgtagttgtg gggacatgga
     1201 accaagaaga gcatgttgag tgggctaaga aaaatactgc tagagcgtat catcttcaag
     1261 acgatggcac ccagacagtc aggatggtgt cacattttta tggaaatggg gatatttgtg
     1321 atataactga caaacccaga caagtgactg taaaactaaa gtgtaaagaa tcagactctc
     1381 ctcatgctgt cactgtgtat atgctagagc ctcactcgtg ccagtatatt cttggggttg
     1441 aatctccagt aatctgtaaa attctagata cagctgatga aaatggactt ctttctctcc
     1501 ccaattaaaa gatattaaag ttgaaagaaa gaaagatgat tgaaaatcat cactttctcc
     1561 tgaccacatc tctttataga gtctcaccat tggaccttgt ctgtagtatc acaaaaagga
     1621 ctggcaacca cactgtgaaa ttcacgtgta tataagagat tacagataaa cttgtaaggc
     1681 agatccttgt ctcacttcat tcattttggt cttgtatgaa ctgattgcgt ttggctttgc
     1741 ttgggtaatg taatttcaaa acaaatctga tccaagcagt ttagtccagc ttatcaaatg
     1801 tcatatacct tgtacttgtt aaagtatttt aaataatata cttactgaat aaattacagc
     1861 acatatgaca agctaatgaa gtaaagataa tttagaaaga agtttctaga agattgtata
     1921 aaatgagggg ccacataaaa tgtataaaat tctagtgcct gaaatccttt cagcaaatgt
     1981 ttctgtgaca gttgctcgct gtcaagcact aaactagaag tggaaataga ggagagcctc
     2041 acagataacc tgagatcact caagaaactg gttttttttt tttttaaatg agaggttgct
     2101 ctttttcttg aacttttatg attcttacca tgaatgagtt tactacagag tacatgtcta
     2161 gtgcagacag ttcgtgactc atctctacat tagaatggtt cattctaaaa ttcactgtgc
     2221 tggctctcgt acgtgcctgc tgtatagtat aaatcttagt tctggacagc tttacagcac
     2281 aatatttatt ttaaagagaa taaaatgtta ttaagcagtc ttttcatgta attagtggca
     2341 gattattcag ttactttatt ttctccttta tcctttttgc atatatttta tccatatgaa
     2401 tctgaacaag gacaaaaaag tggccatagg gactgagaga atactttaga ggcagagcat
     2461 gtttgaggcc ctcagttcag tctcccacaa caaaaataaa aagttggata ttggggttca
     2521 tgcttttgtt cccagcacta agtagacaga ttcaggggat cagaaagttc aaagatagcc
     2581 tggtctacgc caaggatagc cagttctgca ccaaccaggg caacaaagtt gaaagcctat
     2641 cttaaacagt caaaataaaa ggtggtccag atactcctga aaaccagtat ttctgataaa
     2701 agctatatta agaaagggtt tatgaccagg cctaatggca tggcattaat taattaatta
     2761 attaattaat gtaatgccag cacttgagaa gtagatacta gaagaatcag aagttcaaag
     2821 tctgctacat agtgagtttg aagccagcct gggctgcagg agaccttgtc ttagaaatta
     2881 attaattagt taataattaa ttaatatgtg aactttttta ttctacacca agtacattca
     2941 gcacttttgg gtatcctaca attgatttaa ttaattcaat gcctttattg ctagggcggg
     3001 gggtttagtg gtaaagcagt ctaggacagt ggtttaaaac ctgtgggtaa tggccccttt
     3061 aggggttaaa tgaccttttc atgggggagg ggtgtcacct aagtccatca gaaaacatat
     3121 ttacattatg attcataaca gtagcaaaac tacagttaga agtagcaaca aaaagtttta
     3181 tggttgaggt caccacaaca tgaggagctg tatttaggga tcacagcagt aaggtaagtc
     3241 taggaggtga aagaatctgg ctggagactg gagatgcagc tcattggcag actgcttagc
     3301 aaacacaaga tcctggattc catttccagc acagcacaag aaatgaagaa aagaaaaaag
     3361 taaatgactc aacatagtgt cttaacccca gaacttggaa aacaaagaag tattgccatg
     3421 aatttgagac caatctgatt tgccatacac tgtgaattct aggctaatct agaaagagtg
     3481 aatgagatga gacactttct t
//
