LOCUS       NM_021446               1557 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus ergosterol biosynthesis 28 (Erg28), transcript variant
            1, mRNA.
ACCESSION   NM_021446
VERSION     NM_021446.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1557)
  AUTHORS   Easterday,M.C., Dougherty,J.D., Jackson,R.L., Ou,J., Nakano,I.,
            Paucar,A.A., Roobini,B., Dianati,M., Irvin,D.K., Weissman,I.L.,
            Terskikh,A.V., Geschwind,D.H. and Kornblum,H.I.
  TITLE     Neural progenitor genes. Germinal zone expression and analysis of
            genetic overlap in stem cell populations
  JOURNAL   Dev Biol 264 (2), 309-322 (2003)
   PUBMED   14651920
REFERENCE   2  (bases 1 to 1557)
  AUTHORS   Nelson,P.S., Pritchard,C., Abbott,D. and Clegg,N.
  TITLE     The human (PEDB) and mouse (mPEDB) Prostate Expression Databases
  JOURNAL   Nucleic Acids Res 30 (1), 218-220 (2002)
   PUBMED   11752298
REFERENCE   3  (bases 1 to 1557)
  AUTHORS   Ottolenghi,C., Daizadeh,I., Ju,A., Kossida,S., Renault,G.,
            Jacquet,M., Fellous,A., Gilbert,W. and Veitia,R.
  TITLE     The genomic structure of c14orf1 is conserved across eukarya
  JOURNAL   Mamm Genome 11 (9), 786-788 (2000)
   PUBMED   10967139
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC138303.4, AK004480.1 and AI844820.1.
            
            On Feb 15, 2018 this sequence version replaced NM_021446.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC004591.1, AK004480.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-326               AC138303.4         156882-157207
            327-1540            AK004480.1         1-1214
            1541-1557           AI844820.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..1557
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 39.81 cM"
     gene            1..1557
                     /gene="Erg28"
                     /gene_synonym="0610007P14Rik; 1190004E09Rik; ORF11"
                     /note="ergosterol biosynthesis 28"
                     /db_xref="GeneID:58520"
                     /db_xref="MGI:MGI:1915571"
     exon            1..423
                     /gene="Erg28"
                     /gene_synonym="0610007P14Rik; 1190004E09Rik; ORF11"
                     /inference="alignment:Splign:2.1.0"
     exon            424..584
                     /gene="Erg28"
                     /gene_synonym="0610007P14Rik; 1190004E09Rik; ORF11"
                     /inference="alignment:Splign:2.1.0"
     CDS             452..874
                     /gene="Erg28"
                     /gene_synonym="0610007P14Rik; 1190004E09Rik; ORF11"
                     /note="isoform 1 is encoded by transcript variant 1;
                     probable ergosterol biosynthetic protein 28; c14orf1-like
                     protein; ergosterol biosynthetic protein 28 homolog"
                     /codon_start=1
                     /product="ergosterol biosynthetic protein 28 homolog
                     isoform 1"
                     /protein_id="NP_067421.1"
                     /db_xref="CCDS:CCDS26063.1"
                     /db_xref="GeneID:58520"
                     /db_xref="MGI:MGI:1915571"
                     /translation="MSRFLNVLRSWLVMVSIIAMGNTLQSFRDHTFLYEKLYTGKPNL
                     VNGLQARTFGIWTLLSSVIRCLCAIDIHNKTLYHITLWTFLLALGHFLSELFVFGTAA
                     PTVGVLAPLMVASFSILGMLVGLRYLEAEPVSRQKKRN"
     exon            585..675
                     /gene="Erg28"
                     /gene_synonym="0610007P14Rik; 1190004E09Rik; ORF11"
                     /inference="alignment:Splign:2.1.0"
     exon            676..794
                     /gene="Erg28"
                     /gene_synonym="0610007P14Rik; 1190004E09Rik; ORF11"
                     /inference="alignment:Splign:2.1.0"
     exon            795..1541
                     /gene="Erg28"
                     /gene_synonym="0610007P14Rik; 1190004E09Rik; ORF11"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1515..1520
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Erg28"
                     /gene_synonym="0610007P14Rik; 1190004E09Rik; ORF11"
                     /note="hexamer: AATAAA"
     polyA_site      1541
                     /gene="Erg28"
                     /gene_synonym="0610007P14Rik; 1190004E09Rik; ORF11"
                     /note="major polyA site"
ORIGIN      
        1 cgggcgctga cggatggcgt caccacggcg cgctcagaca ccagagccaa cccaggctgt
       61 caccagaagg tttcttggct cctttttctc tctgcgtttt ccccacccct aaaagactga
      121 ctccaaactc agagttccgc cacgctcgac agaagggttt accgcgtgag cggcgtagca
      181 ggaagaggct caggcggcgg caactgctga ttggcagcaa aggagttcac tccctatcgc
      241 ctgctcgaac tgagccagcg tagccaatca gaacgaggac tgacaaaaac aacccaatcc
      301 tggagctggg ctgagggagg gggcgggaac aagtggccca ggtggacttg ggaccggagc
      361 tggcctaggg agagctggtt tgcggatgct gctgatactg ctgcagtagt actggatcgt
      421 caggcagagc gccctctctt ggaggggagt catgagccgc ttcctgaatg tgttacgaag
      481 ctggctggtt atggtgtcca ttatagccat ggggaacaca ctccagagct tccgagacca
      541 cacttttctc tacgagaagc tctacactgg caagccaaac cttgtgaatg gcctccaagc
      601 ccggaccttt gggatctgga cgctgctctc atcagtgatt cgctgcctct gtgccattga
      661 catccacaac aaaacactct atcacatcac actgtggaca ttcctcctcg ccctgggaca
      721 cttcctctca gagttgtttg tatttggaac agcagctccc acagttggtg tgctggcacc
      781 cctgatggta gcaagtttct caatcctggg catgctggtc gggctccggt acctagaggc
      841 agaaccagta tccagacaga agaaaagaaa ttgaggccag ccttgccagc tctgaaacat
      901 cgtcttccac ctccactgtc ttcttcattc accctctatc cttaaaccat ttctgtttgg
      961 ctgcatcctt aactccttca tctaggttca gcatcttaag ctttcgagag ggttttttgt
     1021 tttttgatct taaattttgg tttttggggt ttttttatgt ttttaaattt tttaaggtat
     1081 tcataagaaa aattacttaa catgtatgta taatttagga gtcatttaaa gaaaatactc
     1141 ttgttagtcc ttcaaagtca aggaattctg agaagccccc taatgtgtcc tcccctagct
     1201 ataacccctc tagctccttt tccagtcttt tgcttttctc tgcattcctt gatctgttgt
     1261 ggtgggaaca taactgtgaa gccgcagctg ctgcctgccc agagcagccg cgggcaaggg
     1321 ctgcttcaag gtcctgagca catagactgg gctcctttct attgctgggc ccaggggaca
     1381 ggcagttctt ctgagaagga ctgccctcat gagcaggacc aggctcctct tttatctaca
     1441 ggtggatgaa ggttggaaga gtctgggctg tttttagacc ttttggtcaa ttgtatttgt
     1501 gtaatgcatt ttataataaa tagggaaacc ttctattctg aaaaaaaaaa aaaaaaa
//
