LOCUS       NM_010153               5999 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus erb-b2 receptor tyrosine kinase 3 (Erbb3), mRNA.
ACCESSION   NM_010153 XM_125954
VERSION     NM_010153.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5999)
  AUTHORS   Amato,C.M., Xu,X. and Yao,H.H.
  TITLE     An extragenital cell population contributes to urethra closure
            during mouse penis development
  JOURNAL   Sci Adv 10 (49), eadp0673 (2024)
   PUBMED   39642224
REFERENCE   2  (bases 1 to 5999)
  AUTHORS   Patel,V.N., Aure,M.H., Choi,S.H., Ball,J.R., Lane,E.D., Wang,Z.,
            Xu,Y., Zheng,C., Liu,X., Martin,D., Pailin,J.Y., Prochazkova,M.,
            Kulkarni,A.B., van Kuppevelt,T.H., Ambudkar,I.S., Liu,J. and
            Hoffman,M.P.
  TITLE     Specific 3-O-sulfated heparan sulfate domains regulate salivary
            gland basement membrane metabolism and epithelial differentiation
  JOURNAL   Nat Commun 15 (1), 7584 (2024)
   PUBMED   39217171
  REMARK    Erratum:[Nat Commun. 2024 Oct 10;15(1):8784. doi:
            10.1038/s41467-024-53230-4.. PMID: 39389981]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5999)
  AUTHORS   Kang,Q., Jia,J., Dean,E.D., Yuan,H., Dai,C., Li,Z., Jiang,F.,
            Zhang,X.K., Powers,A.C., Chen,W. and Li,M.
  TITLE     ErbB3 is required for hyperaminoacidemia-induced pancreatic alpha
            cell hyperplasia
  JOURNAL   J Biol Chem 300 (8), 107499 (2024)
   PUBMED   38944125
  REMARK    GeneRIF: ErbB3 is required for hyperaminoacidemia-induced
            pancreatic alpha cell hyperplasia.
REFERENCE   4  (bases 1 to 5999)
  AUTHORS   Guo,Y., Xiang,P., Sun,X., Liu,W., Zhou,J., Yin,B., Hou,L.,
            Qiang,B., Li,H., Shu,P. and Peng,X.
  TITLE     Docking protein 6 (DOK6) selectively docks the neurotrophic
            signaling transduction to restrain peripheral neuropathy
  JOURNAL   Signal Transduct Target Ther 9 (1), 32 (2024)
   PUBMED   38351062
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5999)
  AUTHORS   Racedo,S.E., Liu,Y., Shi,L., Zheng,D. and Morrow,B.E.
  TITLE     Dgcr8 functions in the secondary heart field for outflow tract and
            right ventricle development in mammals
  JOURNAL   Dev Biol 506, 72-84 (2024)
   PUBMED   38110169
REFERENCE   6  (bases 1 to 5999)
  AUTHORS   Meyer,D. and Birchmeier,C.
  TITLE     Multiple essential functions of neuregulin in development
  JOURNAL   Nature 378 (6555), 386-390 (1995)
   PUBMED   7477375
  REMARK    Erratum:[Nature 1995 Dec 14;378(6558):753]
REFERENCE   7  (bases 1 to 5999)
  AUTHORS   Moscoso,L.M., Chu,G.C., Gautam,M., Noakes,P.G., Merlie,J.P. and
            Sanes,J.R.
  TITLE     Synapse-associated expression of an acetylcholine receptor-inducing
            protein, ARIA/heregulin, and its putative receptors, ErbB2 and
            ErbB3, in developing mammalian muscle
  JOURNAL   Dev Biol 172 (1), 158-169 (1995)
   PUBMED   7589796
REFERENCE   8  (bases 1 to 5999)
  AUTHORS   Copeland,N.G., Gilbert,D.J., Schindler,C., Zhong,Z., Wen,Z.,
            Darnell,J.E. Jr., Mui,A.L., Miyajima,A., Quelle,F.W., Ihle,J.N. et
            al.
  TITLE     Distribution of the mammalian Stat gene family in mouse chromosomes
  JOURNAL   Genomics 29 (1), 225-228 (1995)
   PUBMED   8530075
REFERENCE   9  (bases 1 to 5999)
  AUTHORS   Marikovsky,M., Lavi,S., Pinkas-Kramarski,R., Karunagaran,D.,
            Liu,N., Wen,D. and Yarden,Y.
  TITLE     ErbB-3 mediates differential mitogenic effects of NDF/heregulin
            isoforms on mouse keratinocytes
  JOURNAL   Oncogene 10 (7), 1403-1411 (1995)
   PUBMED   7731691
REFERENCE   10 (bases 1 to 5999)
  AUTHORS   Kraus,M.H., Issing,W., Miki,T., Popescu,N.C. and Aaronson,S.A.
  TITLE     Isolation and characterization of ERBB3, a third member of the
            ERBB/epidermal growth factor receptor family: evidence for
            overexpression in a subset of human mammary tumors
  JOURNAL   Proc Natl Acad Sci U S A 86 (23), 9193-9197 (1989)
   PUBMED   2687875
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC106091.1, AC117232.3 and AA119766.1.
            
            On Jun 22, 2018 this sequence version replaced NM_010153.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC106091.1, AY686636.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4876              BC106091.1         18-4893
            4877-5563           AC117232.3         53535-54221         c
            5564-5993           AA119766.1         15-444              c
            5994-5999           AC117232.3         53099-53104         c
FEATURES             Location/Qualifiers
     source          1..5999
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 77.1 cM"
     gene            1..5999
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /note="erb-b2 receptor tyrosine kinase 3"
                     /db_xref="GeneID:13867"
                     /db_xref="MGI:MGI:95411"
     exon            1..216
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..4154
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /EC_number="2.7.10.1"
                     /note="receptor tyrosine-protein kinase erbB-3; v-erb-b2
                     erythroblastic leukemia viral oncogene homolog 3; glial
                     growth factor receptor; c-erbB-3; proto-oncogene-like
                     protein c-ErbB-3; avian erythroblastosis oncogene B 3
                     receptor"
                     /codon_start=1
                     /product="receptor tyrosine-protein kinase erbB-3
                     precursor"
                     /protein_id="NP_034283.1"
                     /db_xref="CCDS:CCDS24283.1"
                     /db_xref="GeneID:13867"
                     /db_xref="MGI:MGI:95411"
                     /translation="MSAIGTLQVLGFLLSLARGSEMGNSQAVCPGTLNGLSVTGDADN
                     QYQTLYKLYEKCEVVMGNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSVLPLPNL
                     RVVRGTQVYDGKFAIFVMLNYNTNSSHALRQLRFTQLTEILLGGVYIEKNDKLCHMDT
                     IDWRDIVRVPDAEIVVKNNGGNCPPCHEVCKGRCWGPGPEDCQILTKTICAPQCNGRC
                     FGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPAPLVYNKLTFQLEPNP
                     HIKYQYGGVCVASCPHNFVVDQTFCVRACPADKMEVDKNGLKMCEPCRGLCPKACEGT
                     GSGSRYQTVDSSNIDGFVNCTKILGNLDFLITGLNGDPWHKIPALDPEKLNVFRTVRE
                     ITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEIS
                     AGRVYISANQQLCYHHSLNWTRLLRGPAEERLDIKYNRPLGECVAEGKVCDPLCSSGG
                     CWGPGPGQCLSCRNYSREGVCVTHCNVLQGEPREFVHEAHCFSCHPECQPMEGTSTCN
                     GSGSDACARCAHFRDGPHCVNSCPHGILGAKGPIYKYPDAQNECRPCHENCTQGCKGP
                     ELQDCLGQAEVLMSKPHLVIAVTVGLTVIFLILGGSFLYWRGRRIQNKRAMRRYLERG
                     ESIEPLDPSEKANKVLARIFKETELRKLKVLGSGVFGTVHKGIWIPEGESIKIPVCIK
                     VIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVR
                     QHRETLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVMLKSPSQVQVADFGVADL
                     LPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVWELMTFGAEPYAGLR
                     LAEIPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPPR
                     YLVIKRASGPGIPPAAEPSALSTKELQDAELEPDLDLDLDVEVEEEGLATTLGSALSL
                     PTGTLTRPRGSQSLLSPSSGYMPMNQSNLGEACLDSAVLGGREQFSRPISLHPIPRGR
                     QTSESSEGHVTGSEAELQERVSMCRSRSRSRSPRPRGDSAYHSQRHSLLTPVTPLSPP
                     GLEEEDGNGYVMPDTHLRGTSSSREGTLSSVGLSSVLGTEEEDEDEEYEYMNRKRRGS
                     PARPPRPGSLEELGYEYMDVGSDLSASLGSTQSCPLHPMAIVPSAGTTPDEDYEYMNR
                     RRGAGGSGGDYAAMGACPAAEQGYEEMRAFQGPGHQAPHVRYARLKTLRSLEATDSAF
                     DNPDYWHSRLFPKANAQRI"
     exon            217..368
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            369..555
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            556..681
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            682..747
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            748..866
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            867..1008
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            1009..1122
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            1123..1243
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1317
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            1318..1408
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..1614
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            1615..1747
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            1748..1838
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            1839..1993
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            1994..2047
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            2048..2183
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            2184..2303
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            2304..2402
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            2403..2588
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            2589..2744
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            2745..2820
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            2821..2967
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            2968..3065
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            3066..3254
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            3255..3326
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            3327..3627
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     exon            3628..5999
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5974..5979
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /note="hexamer: AATAAA"
     polyA_site      5993
                     /gene="Erbb3"
                     /gene_synonym="Erbb-3; Erbb3r; Her3"
                     /note="major polyA site"
ORIGIN      
        1 gcagtttgca acctccgctg ccgccgcggc cacctaatcg ctggctgttc aggtggctgt
       61 cgcctggatg tcctcctaat cttgggggcc ccgggccaga ctcggctggg ctcccttcac
      121 cctccactgt aatcatgagt gcgattggga ctctgcaggt gctgggtttc cttctcagcc
      181 tggcccgggg ttccgagatg ggcaactctc aggcagtatg tcctgggact ctaaacgggc
      241 tgagtgtgac cggcgatgct gacaaccagt accagacact gtacaaactc tatgagaagt
      301 gtgaggtggt catgggtaac ctggagattg tgcttacggg acacaatgct gatctttcct
      361 tcctgcaatg gatccgagaa gtgacaggct atgtactggt ggccatgaat gaattctctg
      421 tactgccctt acctaacctc cgagtggtcc ggggaaccca ggtctacgat gggaagtttg
      481 ccatctttgt catgttgaac tacaatacca actccagcca tgctctgcgc cagctccggt
      541 tcactcagct tactgagatt ctgttagggg gcgtttacat tgagaagaat gacaaacttt
      601 gccacatgga tacaattgac tggagggaca tcgtgagggt tccagacgct gagatagtgg
      661 tgaagaacaa cggggggaac tgtccaccct gtcacgaagt ctgcaagggg cgatgctggg
      721 ggcctggacc agaagactgc cagatattga ccaagaccat ctgtgcccct cagtgtaacg
      781 gtcgctgctt cgggcccaat cctaaccagt gctgccacga tgaatgtgca ggtggctgct
      841 ctggacccca ggacacagat tgcttcgcct gccgacactt caatgacagt ggtgcctgtg
      901 tgcccaggtg tccagcgccc cttgtgtaca acaagctaac gttccagctt gagcccaacc
      961 cccatatcaa gtatcagtac ggaggagtct gtgttgccag ttgtccccat aactttgtgg
     1021 tggatcagac attttgtgtc agggcttgtc ctgctgacaa gatggaagta gataagaatg
     1081 gactcaagat gtgtgagcct tgcagagggc tgtgcccaaa agcctgtgag gggacgggct
     1141 ctggaagccg ctaccagacc gtggactcta gcaatatcga tgggttcgtg aactgtacca
     1201 agatcctggg caacctggac ttcctcatca ctggcctcaa tggtgacccc tggcacaaga
     1261 tccctgcact ggacccggaa aagctcaatg ttttcaggac agtccgggag attacaggct
     1321 acctaaacat ccagtcctgg ccccctcaca tgcacaactt cagtgttttt tccaacctga
     1381 cgaccatcgg gggcagaagc ctctacaatc ggggcttctc cttgttgatc atgaagaact
     1441 tgaatgtcac gtctctgggc ttccggtccc tgaaggaaat tagtgctggg cgtgtctaca
     1501 taagtgccaa tcagcaactt tgttaccacc actctctgaa ctggaccaga cttctgcggg
     1561 ggcccgcaga ggagagactt gacatcaagt acaaccggcc tctgggagaa tgcgtggcag
     1621 agggcaaagt gtgtgatcca ctgtgctcct ctgggggatg ctggggccca ggccctggtc
     1681 agtgcttgtc ttgtcgaaac tacagccggg aaggtgtctg tgtgactcac tgcaacgttc
     1741 tgcaagggga accccgagag tttgttcatg aggctcattg cttctcctgc catccagaat
     1801 gccagcccat ggagggcacc agcacgtgca atggctcggg ctccgacgct tgtgctcgat
     1861 gcgcccattt tcgtgatggg ccccactgtg tgaacagctg cccccatgga atcctaggtg
     1921 ccaaaggtcc aatctacaaa tatccagatg ctcagaatga gtgccggccc tgccacgaga
     1981 actgcaccca agggtgtaag ggaccagaac tacaagactg tttaggccaa gcagaggtat
     2041 taatgagcaa accacacctg gtcatagcgg tgacagtagg actgactgtg atcttcctga
     2101 ttctgggagg ctcttttctc tattggcgtg gacgcaggat tcagaataaa agggctatga
     2161 gacgctactt ggagcggggt gagagcatcg agcctctgga cccaagcgag aaggcaaaca
     2221 aagtcttggc tagaatcttc aaagagacag agctgaggaa acttaaggtg cttggctctg
     2281 gtgtctttgg aactgtacac aaggggattt ggattcccga gggtgaatcc atcaagattc
     2341 cagtctgcat taaagtcatc gaggacaaga gtgggcggca gagttttcag gctgtgactg
     2401 atcacatgct ggccgtcggc agcctggacc atgcccacat tgtacggctg ctgggactgt
     2461 gcccagggtc atctctgcag cttgtcactc agtacttgcc tctgggctct ctccttgatc
     2521 atgtaagaca gcaccgtgag acactgggac cacagctgct gctcaactgg ggagtacaaa
     2581 ttgccaaggg tatgtattac ctcgaggaac acagcatggt gcatagggac cttgcgctcc
     2641 ggaatgtgat gcttaagtca ccgagtcaag tccaggtggc agattttggt gtggctgact
     2701 tgctgccgcc agatgacaag cagttactac acagtgaggc caagactcca attaaatgga
     2761 tggcccttga gagtatccac tttgggaaat acacacacca gagtgatgtc tggagttacg
     2821 gtgtaaccgt ttgggagttg atgaccttcg gggcagagcc ctacgcaggg ctacgactgg
     2881 ctgaaatacc agacctgctg gagaagggag agcggttagc acagccccag atctgcacca
     2941 ttgacgtcta catggtcatg gtcaagtgtt ggatgattga cgagaatatt cgcccaacct
     3001 ttaaagaact ggccaatgag tttaccagga tggcccggga cccaccaagg tatctggtca
     3061 tcaagagagc gagtgggcct ggaatacctc ctgcagcaga gccatctgct ctgagcacca
     3121 aagagttgca ggatgcagag ctggagccag acctggacct cgacctagac gtggaggtag
     3181 aagaggaggg cctggcgacc acactgggtt ctgccctcag cttgcctaca ggaacgctta
     3241 cccggccacg tgggagccag agtcttttaa gtccttcgtc tggatacatg cccatgaacc
     3301 agagcaacct tggggaggct tgtctggatt ctgcggtttt ggggggtcgc gaacagttct
     3361 cccgtcccat ctctctgcac ccgatcccac gggggcgtca aacgtcagag tcatcagagg
     3421 gccatgtgac gggctctgag gctgaactcc aagagagagt atcaatgtgt aggagccgga
     3481 gccggagccg gagcccacgg ccacgtgggg acagtgccta ccattcgcag cgacacagcc
     3541 tgcttactcc cgtcaccccg ctctccccac cagggttaga ggaagaggat ggcaatggtt
     3601 atgtcatgcc agatacgcac ctcagaggta catcctcttc ccgggaaggc accctttcgt
     3661 cagtaggtct cagttctgtg ctgggtaccg aagaggaaga tgaagatgag gagtatgaat
     3721 acatgaaccg gaagaggagg ggtagcccgg ctcggccccc cagacctggt tccctggaag
     3781 agctgggcta tgagtacatg gatgtgggtt cagacctcag tgcttctctg ggcagtacgc
     3841 agagttgccc actccatccc atggccatcg tgccctctgc tggcacgact ccagatgagg
     3901 actatgaata catgaaccgc aggcgtggtg cgggcggttc cggaggggat tatgcagcta
     3961 tgggggcctg cccagcagct gaacaagggt atgaggaaat gcgagctttc caggggcctg
     4021 gacatcaagc cccccatgtt cgttatgccc gcctcaaaac tctgcgtagt ttagaagcca
     4081 ctgactccgc ctttgacaac cccgattact ggcatagcag gcttttccct aaggctaacg
     4141 cccagagaat ttgacctcgg ttccttgaga ctcttgggga acatttgatg gcagctagtg
     4201 cctctttgag ggtaaccctt cctcacccct ttctctgagg tcccacctcc atttctccaa
     4261 gaatgccatc tagttcttgg agatttgtca acatatcgtc acaaactttt tgcggtacat
     4321 agccggctgt gcactctctt ctcttcccaa gcctaggaaa gagaagtttc cctgtgtctc
     4381 tcccttcctg atcccgttcc tcagggagac tccctggaga tatgaaggat tactctccag
     4441 accctttctc tcaggctctt actcattggg attagactct taaactttgc ctttcttccc
     4501 caatcagact ctaaagaagg ggagatgaaa gagaagagaa aaagtaagac ttttgtttat
     4561 gagactttta atcccagagg aagattgaga agctcaaagc tttgaggagt gaagttagga
     4621 gtaggtacca gtgactacga actgaacatg cactgtgagc caggcatcct catactgaac
     4681 cccacctaca ttgtctcagt tataatcttt ccagttttgt gaggtagaac tgatcctgtt
     4741 tcaccaatat ggaatctgag tgttccaaga tagccaacag gtcccggaat ctttgaatag
     4801 tactgaatcc tgtagggttt tttttttctt ttaatatttt taatattttt ttaatattca
     4861 gtaaacaaaa ctgaattctg tgattagtga cttttccatc ttaactaaga acttattgtt
     4921 ctttttagtt tgaggtgaca cagcagaggt tgtactgatt tttctatttt tctaatttaa
     4981 tggatttgtt attatagaca ttacaacccc cccccccgtg aagtcaagaa tttccacctt
     5041 ttctcaaaca aaaaaccatt tctttgacac atttgaatta atagcaggac ttgccctttg
     5101 ggcccattct taggtaagat gagggtcttt gagcacaagt actatgagat ctgtcagtca
     5161 atctaataac caggcaggta attaagtggc tcaagagcaa ataggttatt cagtgcgggt
     5221 gtaccaggca gagatgattc atctaccaag tggaacagga gaggccggct gtgatttcat
     5281 cgtgctattc agaatgggta ctatgtaaac tgtaaggatt atttatttca ggaacttgtc
     5341 actcagcatg tttcagatga cagttgacca caggttacta aaactgtgga cagcaaaacc
     5401 tcagaaaatg gggaattgag ccttgaagaa gcaaagccac aggtccagga ttcaaaatcc
     5461 tcccaattcc catgcctgtg atttaactat aaagtgtatg tgtgtgtgtg taaagccggg
     5521 cctggcgact ggcctgcaac tgtgtagccc aggatggcct tcaactccac acacagcaat
     5581 cccatcttca cctctcaaag gctgtggcta catgtgtgag cttccagact ccgtttgttg
     5641 gtgcactgaa tcaagcaaat gcagccagcc acgttttcct ccagcaccca ggcctctcat
     5701 ctcaggaagg agtggagatg acacaggaca agtaactaga catttttgtg taagctgcag
     5761 gccatttacg ttgcagatac acactcatta caagccaatt cgcaaaggtt ccaagactcc
     5821 tattttggga gctgttctca accagtagtg ataaacttct ggtgggatag aaagaggatc
     5881 catcttcaaa cctcaagtct tcctggatgg gaactggggg gaatgtcttc ttgtaccatt
     5941 aaagtttttt tgttttgttt ttatacgtgt ctaaataaaa atgtcagagt ttttttgtt
//
