LOCUS       NM_007936               6328 bp    mRNA    linear   ROD 04-MAR-2025
DEFINITION  Mus musculus Eph receptor A4 (Epha4), mRNA.
ACCESSION   NM_007936
VERSION     NM_007936.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6328)
  AUTHORS   Scavuzzo,M.A., Szlachcic,W.J., Hill,M.C., Ziojla,N.M., Teaw,J.,
            Carlson,J.C., Tiessen,J., Chmielowiec,J., Martin,J.F. and
            Borowiak,M.
  TITLE     Pancreatic organogenesis mapped through space and time
  JOURNAL   Exp Mol Med 57 (1), 204-220 (2025)
   PUBMED   39779976
REFERENCE   2  (bases 1 to 6328)
  AUTHORS   Pappas,M.P., Kawakami,H., Corcoran,D., Chen,K.Q., Scott,E.P.,
            Wong,J., Gearhart,M.D., Nishinakamura,R., Nakagawa,Y. and
            Kawakami,Y.
  TITLE     Sall4 regulates posterior trunk mesoderm development by promoting
            mesodermal gene expression and repressing neural genes in the
            mesoderm
  JOURNAL   Development 151 (5) (2024)
   PUBMED   38345319
REFERENCE   3  (bases 1 to 6328)
  AUTHORS   Rasool,D., Burban,A., Sharanek,A., Madrigal,A., Hu,J., Yan,K.,
            Qu,D., Voss,A.K., Slack,R.S., Thomas,T., Bonni,A., Picketts,D.J.,
            Soleimani,V.D., Najafabadi,H.S. and Jahani-Asl,A.
  TITLE     PHF6-mediated transcriptional control of NSC via Ephrin receptors
            is impaired in the intellectual disability syndrome BFLS
  JOURNAL   EMBO Rep 25 (3), 1256-1281 (2024)
   PUBMED   38429579
REFERENCE   4  (bases 1 to 6328)
  AUTHORS   Cash,A., de Jager,C., Brickler,T., Soliman,E., Ladner,L.,
            Kaloss,A.M., Zhu,Y., Pridham,K.J., Mills,J., Ju,J., Basso,E.K.G.,
            Chen,M., Johnson,Z., Sotiropoulos,Y., Wang,X., Xie,H., Matson,J.B.,
            Marvin,E.A. and Theus,M.H.
  TITLE     Endothelial deletion of EPH receptor A4 alters single-cell profile
            and Tie2/Akap12 signaling to preserve blood-brain barrier integrity
  JOURNAL   Proc Natl Acad Sci U S A 120 (41), e2204700120 (2023)
   PUBMED   37796990
  REMARK    GeneRIF: Endothelial deletion of EPH receptor A4 alters single-cell
            profile and Tie2/Akap12 signaling to preserve blood-brain barrier
            integrity.
REFERENCE   5  (bases 1 to 6328)
  AUTHORS   Altounian,M., Bellon,A. and Mann,F.
  TITLE     Neuronal miR-17-5p contributes to interhemispheric cortical
            connectivity defects induced by prenatal alcohol exposure
  JOURNAL   Cell Rep 42 (9), 113020 (2023)
   PUBMED   37610874
REFERENCE   6  (bases 1 to 6328)
  AUTHORS   Becker,N., Gilardi-Hebenstreit,P., Seitanidou,T., Wilkinson,D. and
            Charnay,P.
  TITLE     Characterisation of the Sek-1 receptor tyrosine kinase
  JOURNAL   FEBS Lett 368 (2), 353-357 (1995)
   PUBMED   7628636
REFERENCE   7  (bases 1 to 6328)
  AUTHORS   Nieto,M.A., Gilardi-Hebenstreit,P., Charnay,P. and Wilkinson,D.G.
  TITLE     A receptor protein tyrosine kinase implicated in the segmental
            patterning of the hindbrain and mesoderm
  JOURNAL   Development 116 (4), 1137-1150 (1992)
   PUBMED   1295734
REFERENCE   8  (bases 1 to 6328)
  AUTHORS   Gilardi-Hebenstreit,P., Nieto,M.A., Frain,M., Mattei,M.G.,
            Chestier,A., Wilkinson,D.G. and Charnay,P.
  TITLE     An Eph-related receptor protein tyrosine kinase gene segmentally
            expressed in the developing mouse hindbrain
  JOURNAL   Oncogene 7 (12), 2499-2506 (1992)
   PUBMED   1281307
  REMARK    Erratum:[Oncogene. 1993 Apr;8(4):1103. PMID: 8455939]
REFERENCE   9  (bases 1 to 6328)
  AUTHORS   Wilks,A.F.
  TITLE     Two putative protein-tyrosine kinases identified by application of
            the polymerase chain reaction
  JOURNAL   Proc Natl Acad Sci U S A 86 (5), 1603-1607 (1989)
   PUBMED   2466296
REFERENCE   10 (bases 1 to 6328)
  AUTHORS   Hanks,S.K., Quinn,A.M. and Hunter,T.
  TITLE     The protein kinase family: conserved features and deduced phylogeny
            of the catalytic domains
  JOURNAL   Science 241 (4861), 42-52 (1988)
   PUBMED   3291115
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            X65138.1, AK147698.1 and AC164875.14.
            
            On Feb 7, 2006 this sequence version replaced NM_007936.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X65138.1, AK147698.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            NMD candidate          :: PMID: 7628636
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6                 X65138.1           1-6
            7-4434              AK147698.1         3-4430
            4435-5505           AK147698.1         4433-5503
            5506-6328           AC164875.14        11639-12461
FEATURES             Location/Qualifiers
     source          1..6328
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 39.55 cM"
     gene            1..6328
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /note="Eph receptor A4"
                     /db_xref="GeneID:13838"
                     /db_xref="MGI:MGI:98277"
     exon            1..148
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     CDS             58..3018
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /EC_number="2.7.10.1"
                     /note="ephrin type-A receptor 4; tyrosine-protein kinase
                     receptor MPK-3; tyrosine-protein kinase receptor SEK-1"
                     /codon_start=1
                     /product="ephrin type-A receptor 4 precursor"
                     /protein_id="NP_031962.2"
                     /db_xref="CCDS:CCDS35627.1"
                     /db_xref="GeneID:13838"
                     /db_xref="MGI:MGI:98277"
                     /translation="MAGIFYFILFSFLFGICDAVTGSRVYPANEVTLLDSRSVQGELG
                     WIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEASQNNWLRTDWITREGAQRVYIEIK
                     FTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRESQFGKIDTIAADESFTQVDIG
                     DRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTI
                     TGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGHEEQNGECQAC
                     KIGYYKALSTDASCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLN
                     LISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNG
                     LKTTRVSITDLLAHTNYTFEIWAVNGVSKYNPSPDQSVSVTVTTNQAAPSSIALVQAK
                     EVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPLTS
                     YVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAA
                     FVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIE
                     KVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNI
                     IHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDM
                     SYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAY
                     RKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQL
                     MLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGSESSRPNTALLDPSSPEFSAVV
                     SVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHMSQDDLARIGITAITHQNKILSSVQAM
                     RTQMQQMHGRMVPV"
     exon            149..216
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     exon            217..880
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     exon            881..1036
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1375
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     exon            1376..1500
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     exon            1501..1660
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     exon            1661..1772
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     exon            1773..1831
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     exon            1832..1945
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     exon            1946..2131
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     exon            2132..2193
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     exon            2194..2403
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     exon            2404..2553
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     exon            2554..2747
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     exon            2748..2903
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     exon            2904..3841
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     exon            3842..6328
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4343..4348
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
                     /note="hexamer: AATATA"
     polyA_site      4367
                     /gene="Epha4"
                     /gene_synonym="2900005C20Rik; Cek8; Hek8; rb; Sek; Sek1;
                     Tyro1"
ORIGIN      
        1 taagcattta ttccactggg atagaagcgg caggagcagc gttggcaccg gcgaaccatg
       61 gctgggattt tctatttcat cctcttttcg tttctctttg gaatttgcga cgctgtcacc
      121 ggttctaggg tataccccgc gaatgaagtt actttattgg attccagatc tgttcaggga
      181 gagcttgggt ggatagcaag ccctctggaa ggagggtggg aggaagtgag cattatggat
      241 gagaaaaata caccgatccg aacctaccag gtgtgcaacg tgatggaagc cagccagaac
      301 aactggctgc gaactgactg gatcacccgc gaaggggcgc agagggtgta cattgaaatt
      361 aagttcactc taagggactg caacagtctt ccgggcgtca tggggacttg caaggagacg
      421 tttaacctct actactatga gtcggacaac gacaaggagc gcttcatcag agagagccag
      481 tttggcaaga tcgacaccat cgcagctgat gagagcttca cgcaggtgga cattggtgac
      541 cgaatcatga aactcaacac tgagatccgg gatgtagggc cactgagcaa gaaagggttt
      601 tacctggctt ttcaggatgt gggtgcttgc atcgccctgg tgtctgtccg tgtgttctac
      661 aagaagtgtc cactcaccgt tcgaaatcta gcccagtttc ctgataccat tactggggct
      721 gatacctctt ccctggtgga agttcgaggc tcctgtgtca acaactcaga agagaaggat
      781 gtgccaaaaa tgtactgtgg ggcagatggt gaatggctgg tacccattgg caactgccta
      841 tgcaacgctg ggcacgagga gcagaatggt gaatgccaag cttgcaaaat tggatattac
      901 aaagctcttt ccacggacgc ctcctgtgcc aagtgtccac cgcacagcta ctctgtctgg
      961 gaaggagcca cgtcctgcac ctgtgaccga ggctttttca gagctgacaa cgatgcagcc
     1021 tccatgccct gcacccgccc accatctgct cccctcaact tgatttctaa tgtcaacgag
     1081 acatcggtga acttggaatg gagcagccct cagaacacag gtggccgtca ggacatttct
     1141 tacaacgtgg tctgcaagaa atgtggagct ggtgatccca gcaagtgccg gccctgtgga
     1201 agtggagtcc actacacacc acagcagaac ggactcaaga cgaccagagt ctccatcact
     1261 gacctcctag cacacaccaa ttacacgttt gagatctggg cagtgaatgg agtgtctaag
     1321 tataacccta gcccggacca gtccgtgtct gtcacagtga caaccaacca agcagcacca
     1381 tcatccattg ctttggtcca ggctaaagaa gttacaagat atagcgtagc tctggcttgg
     1441 ctggaaccag atcgaccaaa tggagtcatc ttagaatatg aagtcaaata ttatgaaaag
     1501 gatcagaatg aacgcagcta tcgcatagtc cggacagctg ccaggaacac agatatcaaa
     1561 ggcctgaacc ctctgacttc ctatgttttt cacgtgcgag ccaggaccgc tgctggctac
     1621 ggagacttca gcgagcccct ggaagtcact actaatacag tgccttcccg catcattggc
     1681 gatggagcca actccactgt cctgctggtc tccgtctctg gcagtgtggt cctcgtggtc
     1741 attctcattg cagcttttgt gatcagccga agacggagta agtacagcaa agcgaaacaa
     1801 gaagcagatg aagagaaaca tttgaatcaa ggtgttagaa cttatgtgga tccctttaca
     1861 tacgaagacc ccaaccaggc agttcgagaa tttgccaaag aaatcgatgc atcctgcatt
     1921 aaaattgaaa aggtcatagg agttggtgaa tttggagagg tctgcagtgg gcgtctcaaa
     1981 gtgcccggca agagagagat ctgtgtggcc atcaagactc tgaaagctgg ctatactgac
     2041 aagcagagga gagacttcct gagtgaggcc agcatcatgg gacagtttga ccacccaaac
     2101 ataatccacc tggaaggcgt tgtcaccaaa tgtaaaccgg taatgatcat aacggagtac
     2161 atggagaacg gctccttgga tgctttcctc aggaagaatg atggccgctt tacagtcatt
     2221 cagctggtgg gcatgctccg gggcattggc tcggggatga agtacttatc tgatatgagc
     2281 tatgtgcatc gagacctggc tgccaggaac atcctggtaa acagcaactt ggtctgcaag
     2341 gtgtctgact ttggcatgtc cagggtgctg gaggatgacc ccgaagcagc ctacactacc
     2401 aggggtggca agattcctat ccggtggact gcgccagaag caattgcgta tcgtaaattt
     2461 acctcagcca gtgatgtctg gagctacgga atcgttatgt gggaagtgat gtcatatgga
     2521 gagagaccgt actgggatat gtccaatcaa gatgtgatca aagccatcga ggaagggtac
     2581 cggctacccc ctccaatgga ctgccccatt gccctccatc agttaatgct ggactgctgg
     2641 cagaaagaga gaagtgacag gcctaaattt gggcagatcg tcaacatgct ggacaaactc
     2701 atccgcaatc ccaacagcct gaagaggaca gggtcggaga gttccagacc aaacacagcc
     2761 ttgttagatc ccagctcccc tgaattctct gctgtagtat cagtgggcga ctggctgcag
     2821 gccatcaaaa tggaccggta taaggacaac ttcacggccg ccgggtacac gacactagaa
     2881 gccgtggttc acatgagcca ggacgacctg gcgagaattg gcatcaccgc catcacgcac
     2941 cagaataaga ttttgagcag cgtccaggcg atgcgaaccc agatgcagca gatgcatggc
     3001 aggatggttc ctgtctgagc cagtaccgaa tagactcaaa actctcgaat agtttacctc
     3061 atccatgcac tttaattgaa gaactgcact ttttttactt tgtcttcgcc ctctgaaatt
     3121 aaaggaaaac aaacaaacaa aaaacaaaaa caaaaatatc tgcagcgttg cttggtgtaa
     3181 gagattgctg aaaccatggg gcttataatg aatgaccttg atcatcagaa ttaaacctgg
     3241 agccagtaat ttctcagaag aactctgtcc atcgctggtg tgtaaaatac atgtacttat
     3301 ataaataaaa ctctgcctct gagtttcgat gctgtatttc ccgtcagagg cttttcaagt
     3361 caccctaatc ctttctctgt ctggaatttc aagggaagga tttcatctgt ggcattaata
     3421 acagtcatca ctccttacca gaaagaagac ctgctgtgcc caggagcact gttaaaggac
     3481 tcaatggtgg ctttcagggc tcggtttata ccacagaaga aaatccaggt gaaagccact
     3541 tggcccattc atgctgcctc ttcaatggcc aggacacctg gtggattttt atgacatagg
     3601 gggggttaga aagaaaagaa aatggatttt taaaacatgc gaactcccaa gacctattaa
     3661 ccctaactgg acaaatgagg tctctttggg gctgaggctg tgccatataa agtcttcttt
     3721 gagaatgcta caaacttctc ataactacct tatggatagt gggctgagac aatcctgaat
     3781 ggagaatttt cacacacaca cacacacacc ccttcaaaga ggcaactccc aaatttacaa
     3841 gggaatagat tctggtatct cagcctcaca gcccttcctg ttgattacat aagcgcttgg
     3901 aagaaaatag aacacaccct ccaccgttcc ttctgaatgt ttttctttgg cttctcttct
     3961 gccggttttt gaggcaaaga cacgacaaaa cacctgcacc tgaacagcag aagaaatgtg
     4021 tcaagtcccc ttcgcccagg aaaacgacat ccagctttgg catctgttct cagctgcact
     4081 gaggaatgtg ctgtctcgag gcaccagctc tgcagagccc ttgctcccaa actccttgtg
     4141 gttttattta tacgtatttc catatttcat tcctgtacgg ccccgctgca tccgtgtggc
     4201 agcaagtgac catatgttac aggttttact atggacgcca ggtcaggcgc caccacgcag
     4261 aacaaagcca gttccgcaag ctgcctccga tacgcaatgc taaagtgaca ttttacccag
     4321 ggtgtgccat tgcagtgata taaatatatt tttttcctag actaaaatat gacctgaata
     4381 tctcttttga tgtgtgtaca tagagtgtgt gtgtgtgtgt gtgtgtgtgt gtgtatgtga
     4441 gtgtgtatgg ggtgtgtgtg tgtgtgtgtg tgtgtgtgtg taacctcatg cttagaactg
     4501 cctgtgaatg ttgtggaatg ctatacctgg agagttctgg tttattacca gttcaaagat
     4561 aaggaaagag tcacatgata tacaagaccc ggagaccatg tccgtcccct tgggaagaca
     4621 gcttggaaac gctacatgtt ctttatctgt aagtgtaatg tgtctgtcac attcatccta
     4681 agaagcagtt ctttggacag atgttttcac cttgatggtg gaatgatttt tagatataag
     4741 cctgactcgc cgatttcaca atggagagag aaggggatgg aatccaattt gtgaccccag
     4801 atggagtata agtcgccttt gtttccctgc ataaatgaac ttgttgaatg cgaacaaata
     4861 tatgcaattc atatactttt ggaagatgaa cttaagatat gtgtgtcagc cttgagatga
     4921 tgtgtctgga gtaatacttt gtgtcccagt gtcacagaaa aatacataca tgccagtggc
     4981 tcttgaggtt aatgtagttg ggatgaaatg gcctctagca attccaggtt ccccaattac
     5041 atgtggaaag ttctggtaat taatatgcag ctaactactt atgcccttga aagtatacca
     5101 gtcttctaga atcggagttc tggtgtatga agattcagta tcgacaggat atgtatacca
     5161 aactccagcc agcatactgc cattttactt aacctgagag gctgccttgc ttattctgag
     5221 ctatggtcac agaaactgtg gccatttata taagctataa catcaaatca gggaattaga
     5281 aaaaaaaaaa acggggaaaa gattctgaac catatattgt tgaataagta aagaaaatca
     5341 ccaataaata tttattgcat tctgacaggg tgtatggcat tgtattctca taactatgcc
     5401 agagtgacaa agttatttca ccccttttga ggggacctta atatattttt aaagggatgt
     5461 gcctatgcat tgatgcctga aaaataggtg taaaaaaaaa aaaaaagatg aacctctgag
     5521 tgcatcatct ttcccagagg tcaggtggga ggaggtcaac ttctgggtct gtgtccagcc
     5581 caggagcaag cgctggcctt gggagctgga aggctaaaat ctagtcaaat ctactaaaca
     5641 gctttgagct gttccctgca ccaaatcaag ccgtttcacc acgtgtctgc aggctctgag
     5701 gtttttattt tttggcgatc ttctaaatga aatgttctgg tgtgttttaa agactagagg
     5761 aaaggttgtg ttcacaacat gattactgtg tgtgttctga gacctcttgt attcatctgt
     5821 gaaggggacg tgtattaatc catacactcc tatagcctcg actatttgtc tgaagacact
     5881 taaattttga ccagtaaagg aaagttctag aagcaatatt ttcactcctt tagcattgtc
     5941 caaataacat caagtattaa taaacgctga agagtgtatt tattttgtat tactccaagt
     6001 ctgttggaat atgcaaggac tgtggttata attagaatgt ataaggcata ttataattta
     6061 gttcattctg aaaaagaagt tagctgaaca tctcttggtt catacatgtt ccaaattttg
     6121 aacaatcttt tgagttagcc atagattttt ctattttgtt tttatttgtc aaggtatttt
     6181 tttcttccct tcatgaactt taggtacaca taacttatgt catttattta tggtctttta
     6241 tacctagttt gtaaagttgt aaaatagcaa actaaatgca aagagtttgc atttgaaagt
     6301 aataaagtag ttgccgtata caaacctg
//
