LOCUS       NM_028905               1106 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus exosomal polycystin 1 interacting protein (Epcip),
            transcript variant 1, mRNA.
ACCESSION   NM_028905 NM_027632
VERSION     NM_028905.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1106)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1106)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1106)
  AUTHORS   Gitton,Y., Dahmane,N., Baik,S., Ruiz i Altaba,A., Neidhardt,L.,
            Scholze,M., Herrmann,B.G., Kahlem,P., Benkahla,A., Schrinner,S.,
            Yildirimman,R., Herwig,R., Lehrach,H. and Yaspo,M.L.
  CONSRTM   HSA21 expression map initiative
  TITLE     A gene expression map of human chromosome 21 orthologues in the
            mouse
  JOURNAL   Nature 420 (6915), 586-590 (2002)
   PUBMED   12466855
REFERENCE   4  (bases 1 to 1106)
  AUTHORS   Reymond,A., Marigo,V., Yaylaoglu,M.B., Leoni,A., Ucla,C.,
            Scamuffa,N., Caccioppoli,C., Dermitzakis,E.T., Lyle,R., Banfi,S.,
            Eichele,G., Antonarakis,S.E. and Ballabio,A.
  TITLE     Human chromosome 21 gene expression atlas in the mouse
  JOURNAL   Nature 420 (6915), 582-586 (2002)
   PUBMED   12466854
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC141885.3.
            
            On Jun 12, 2019 this sequence version replaced NM_028905.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK016554.1, AK043035.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-121               AC141885.3         10984-11104
            122-369             AC141885.3         20058-20305
            370-1106            AC141885.3         23880-24616
FEATURES             Location/Qualifiers
     source          1..1106
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 52.35 cM"
     gene            1..1106
                     /gene="Epcip"
                     /gene_synonym="4931406G06Rik; 4932438H23Rik"
                     /note="exosomal polycystin 1 interacting protein"
                     /db_xref="GeneID:74387"
                     /db_xref="MGI:MGI:1921637"
     exon            1..121
                     /gene="Epcip"
                     /gene_synonym="4931406G06Rik; 4932438H23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            122..369
                     /gene="Epcip"
                     /gene_synonym="4931406G06Rik; 4932438H23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            370..1106
                     /gene="Epcip"
                     /gene_synonym="4931406G06Rik; 4932438H23Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             434..1072
                     /gene="Epcip"
                     /gene_synonym="4931406G06Rik; 4932438H23Rik"
                     /note="uncharacterized protein C21orf62 homolog;
                     polycystin-1-interacting protein 1"
                     /codon_start=1
                     /product="exosomal polycystin-1-interacting protein
                     precursor"
                     /protein_id="NP_083181.2"
                     /db_xref="GeneID:74387"
                     /db_xref="MGI:MGI:1921637"
                     /translation="MTSPSSFCLLLLQALGIVALGHFTKAQNNTLIFTKGNTIRNCSC
                     PVDIRDCDYSLANLICSCKSILPSAMEQTSYHGHLTIWFTDISTLGHVLKFTLVQDLK
                     LSLCGSSTFPTKYLAICGLQRLRIHTKARHPSRGQSLLIHSRREGSSLYKGWQTCMFI
                     SFLDVALFNGDSSLKSYSIDNISSLASDFPDFSYFKTSPMPSNRSYVVTVIY"
ORIGIN      
        1 gcattccacc cggcttgcag attaaagcag ctgtcaagcc agggtgaagg cgcagtggcc
       61 agggaagagc tccaaggtct gcagattgga caggcaaggc cctgccgtgg ggccgcaaaa
      121 tccctctcac cagaatgaat cagaatccta caagaattgc atcgatatct gagagcagta
      181 ccagtggtga cctcatgatc tcctcgtcag ttctgcctgt gaagggtccc accatctcta
      241 acatcaccac actggagcct cagcttctga gacaggaact cttacagatg agccacagac
      301 tagagcacgt ttatgcgcac cacgggagca catgctatca gtgctggcgg agagtttggg
      361 ggtaaggagg tgacctacaa tggactggct catgagggag aaacaggaac acaccagtcc
      421 atgctggaca agaatgacat caccttccag cttctgcctc cttctgctcc aagcgctagg
      481 catcgttgcc cttggccact tcacaaaagc tcagaacaac acactgattt tcacaaaagg
      541 aaataccatt cgcaactgca gctgcccagt agacatcagg gactgtgact acagtttggc
      601 taacttgata tgcagctgta agtctatcct gccttctgcc atggagcaaa ccagctatca
      661 tggccatctg accatctggt tcacagatat atccacattg ggccacgtgc tgaagttcac
      721 tctggtccaa gacttgaagc tttccctatg tggttccagc accttcccca ccaagtacct
      781 ggctatctgt gggctgcaga ggcttcgcat ccatactaag gccaggcatc cctcccgggg
      841 gcagagtttg ctcatccaca gcagaaggga aggcagttcc ttgtacaaag gctggcaaac
      901 atgtatgttc atctcattct tagatgtggc tcttttcaac ggggactcat ctttaaagtc
      961 atacagtatt gacaacattt ctagcctcgc cagtgacttt cctgactttt cttactttaa
     1021 aacgtcccca atgccaagca acagaagcta tgttgtcaca gttatttact agcatcctgt
     1081 gtccctccac caggaactct aaaaaa
//
