LOCUS       NM_001163695             858 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus exosomal polycystin 1 interacting protein (Epcip),
            transcript variant 2, mRNA.
ACCESSION   NM_001163695
VERSION     NM_001163695.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 858)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 858)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 858)
  AUTHORS   Gitton,Y., Dahmane,N., Baik,S., Ruiz i Altaba,A., Neidhardt,L.,
            Scholze,M., Herrmann,B.G., Kahlem,P., Benkahla,A., Schrinner,S.,
            Yildirimman,R., Herwig,R., Lehrach,H. and Yaspo,M.L.
  CONSRTM   HSA21 expression map initiative
  TITLE     A gene expression map of human chromosome 21 orthologues in the
            mouse
  JOURNAL   Nature 420 (6915), 586-590 (2002)
   PUBMED   12466855
REFERENCE   4  (bases 1 to 858)
  AUTHORS   Reymond,A., Marigo,V., Yaylaoglu,M.B., Leoni,A., Ucla,C.,
            Scamuffa,N., Caccioppoli,C., Dermitzakis,E.T., Lyle,R., Banfi,S.,
            Eichele,G., Antonarakis,S.E. and Ballabio,A.
  TITLE     Human chromosome 21 gene expression atlas in the mouse
  JOURNAL   Nature 420 (6915), 582-586 (2002)
   PUBMED   12466854
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC141885.3.
            
            On Jun 12, 2019 this sequence version replaced NM_001163695.1.
            
            Transcript Variant: This variant (2) lacks an alternate exon in the
            5' UTR, compared to variant 1. Both variants 1 and 2 encode the
            same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK035767.1, BB586926.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-121               AC141885.3         10984-11104
            122-858             AC141885.3         23880-24616
FEATURES             Location/Qualifiers
     source          1..858
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 52.35 cM"
     gene            1..858
                     /gene="Epcip"
                     /gene_synonym="4931406G06Rik; 4932438H23Rik"
                     /note="exosomal polycystin 1 interacting protein"
                     /db_xref="GeneID:74387"
                     /db_xref="MGI:MGI:1921637"
     exon            1..121
                     /gene="Epcip"
                     /gene_synonym="4931406G06Rik; 4932438H23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            122..858
                     /gene="Epcip"
                     /gene_synonym="4931406G06Rik; 4932438H23Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..824
                     /gene="Epcip"
                     /gene_synonym="4931406G06Rik; 4932438H23Rik"
                     /note="uncharacterized protein C21orf62 homolog;
                     polycystin-1-interacting protein 1"
                     /codon_start=1
                     /product="exosomal polycystin-1-interacting protein
                     precursor"
                     /protein_id="NP_001157167.2"
                     /db_xref="GeneID:74387"
                     /db_xref="MGI:MGI:1921637"
                     /translation="MTSPSSFCLLLLQALGIVALGHFTKAQNNTLIFTKGNTIRNCSC
                     PVDIRDCDYSLANLICSCKSILPSAMEQTSYHGHLTIWFTDISTLGHVLKFTLVQDLK
                     LSLCGSSTFPTKYLAICGLQRLRIHTKARHPSRGQSLLIHSRREGSSLYKGWQTCMFI
                     SFLDVALFNGDSSLKSYSIDNISSLASDFPDFSYFKTSPMPSNRSYVVTVIY"
ORIGIN      
        1 gcattccacc cggcttgcag attaaagcag ctgtcaagcc agggtgaagg cgcagtggcc
       61 agggaagagc tccaaggtct gcagattgga caggcaaggc cctgccgtgg ggccgcaaaa
      121 tgtgacctac aatggactgg ctcatgaggg agaaacagga acacaccagt ccatgctgga
      181 caagaatgac atcaccttcc agcttctgcc tccttctgct ccaagcgcta ggcatcgttg
      241 cccttggcca cttcacaaaa gctcagaaca acacactgat tttcacaaaa ggaaatacca
      301 ttcgcaactg cagctgccca gtagacatca gggactgtga ctacagtttg gctaacttga
      361 tatgcagctg taagtctatc ctgccttctg ccatggagca aaccagctat catggccatc
      421 tgaccatctg gttcacagat atatccacat tgggccacgt gctgaagttc actctggtcc
      481 aagacttgaa gctttcccta tgtggttcca gcaccttccc caccaagtac ctggctatct
      541 gtgggctgca gaggcttcgc atccatacta aggccaggca tccctcccgg gggcagagtt
      601 tgctcatcca cagcagaagg gaaggcagtt ccttgtacaa aggctggcaa acatgtatgt
      661 tcatctcatt cttagatgtg gctcttttca acggggactc atctttaaag tcatacagta
      721 ttgacaacat ttctagcctc gccagtgact ttcctgactt ttcttacttt aaaacgtccc
      781 caatgccaag caacagaagc tatgttgtca cagttattta ctagcatcct gtgtccctcc
      841 accaggaact ctaaaaaa
//
