LOCUS       NM_013513               3920 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus erythrocyte membrane protein band 4.2 (Epb42), mRNA.
ACCESSION   NM_013513
VERSION     NM_013513.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3920)
  AUTHORS   Matte,A., Wilson,A.B., Gevi,F., Federti,E., Recchiuti,A., Ferri,G.,
            Brunati,A.M., Pagano,M.A., Russo,R., Leboeuf,C., Janin,A.,
            Timperio,A.M., Iolascon,A., Gremese,E., Dang,L., Mohandas,N.,
            Brugnara,C. and De Franceschi,L.
  TITLE     Mitapivat reprograms the RBC metabolome and improves anemia in a
            mouse model of hereditary spherocytosis
  JOURNAL   JCI Insight 8 (20), e172656 (2023)
   PUBMED   37676741
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3920)
  AUTHORS   Huang,Y.S., Delgadillo,L.F., Cyr,K.H., Kingsley,P.D., An,X.,
            McGrath,K.E., Mohandas,N., Conboy,J.G., Waugh,R.E., Wan,J. and
            Palis,J.
  TITLE     Circulating primitive erythroblasts establish a functional, protein
            4.1R-dependent cytoskeletal network prior to enucleating
  JOURNAL   Sci Rep 7 (1), 5164 (2017)
   PUBMED   28701737
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3920)
  AUTHORS   Huang,H.M., Bauer,D.C., Lelliott,P.M., Greth,A., McMorran,B.J.,
            Foote,S.J. and Burgio,G.
  TITLE     A novel ENU-induced ankyrin-1 mutation impairs parasite invasion
            and increases erythrocyte clearance during malaria infection in
            mice
  JOURNAL   Sci Rep 6, 37197 (2016)
   PUBMED   27848995
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3920)
  AUTHORS   Liu,X., Jiao,Y., Cao,Y., Deng,N., Ma,Y., Hasty,K.A., Kang,A.,
            Chen,H., Stuart,J.M. and Gu,W.
  TITLE     Decreased expression levels of Ifi genes is associated to the
            increased resistance to spontaneous arthritis disease in mice
            deficiency of IL-1RA
  JOURNAL   BMC Immunol 17 (1), 25 (2016)
   PUBMED   27480124
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3920)
  AUTHORS   Baldwin,M.R., Li,X., Hanada,T., Liu,S.C. and Chishti,A.H.
  TITLE     Merozoite surface protein 1 recognition of host glycophorin A
            mediates malaria parasite invasion of red blood cells
  JOURNAL   Blood 125 (17), 2704-2711 (2015)
   PUBMED   25778531
REFERENCE   6  (bases 1 to 3920)
  AUTHORS   White,R.A., Peters,L.L., Adkison,L.R., Korsgren,C., Cohen,C.M. and
            Lux,S.E.
  TITLE     The murine pallid mutation is a platelet storage pool disease
            associated with the protein 4.2 (pallidin) gene
  JOURNAL   Nat Genet 2 (1), 80-83 (1992)
   PUBMED   1284644
REFERENCE   7  (bases 1 to 3920)
  AUTHORS   Korsgren,C. and Cohen,C.M.
  TITLE     Organization of the gene for human erythrocyte membrane protein
            4.2: structural similarities with the gene for the a subunit of
            factor XIII
  JOURNAL   Proc Natl Acad Sci U S A 88 (11), 4840-4844 (1991)
   PUBMED   2052563
REFERENCE   8  (bases 1 to 3920)
  AUTHORS   Sung,L.A., Chien,S., Chang,L.S., Lambert,K., Bliss,S.A.,
            Bouhassira,E.E., Nagel,R.L., Schwartz,R.S. and Rybicki,A.C.
  TITLE     Molecular cloning of human protein 4.2: a major component of the
            erythrocyte membrane
  JOURNAL   Proc Natl Acad Sci U S A 87 (3), 955-959 (1990)
   PUBMED   1689063
REFERENCE   9  (bases 1 to 3920)
  AUTHORS   Korsgren,C., Lawler,J., Lambert,S., Speicher,D. and Cohen,C.M.
  TITLE     Complete amino acid sequence and homologies of human erythrocyte
            membrane protein band 4.2
  JOURNAL   Proc Natl Acad Sci U S A 87 (2), 613-617 (1990)
   PUBMED   2300550
REFERENCE   10 (bases 1 to 3920)
  AUTHORS   Graff,R.J., Martin-Morgan,D. and Kurtz,M.E.
  TITLE     Multiplicity of chromosome 2 histocompatibility genes: new loci,
            H-44 and H-45
  JOURNAL   Immunogenetics 26 (1-2), 111-114 (1987)
   PUBMED   3301647
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BY230962.1, AK133896.1 and
            AK143841.1.
            
            On Aug 20, 2015 this sequence version replaced NM_013513.2.
            
            Summary: The protein encoded by this gene is the key component of a
            macromolecular complex involved in the structure of erythrocytes.
            [provided by RefSeq, Aug 2015].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK143841.1, AK133896.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164140
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-109               BY230962.1         2-110
            110-2130            AK133896.1         2-2022
            2131-3590           AK133896.1         2024-3483
            3591-3920           AK143841.1         3449-3778
FEATURES             Location/Qualifiers
     source          1..3920
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 60.37 cM"
     gene            1..3920
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /note="erythrocyte membrane protein band 4.2"
                     /db_xref="GeneID:13828"
                     /db_xref="MGI:MGI:95402"
     exon            1..294
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            295..480
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            481..714
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            715..833
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            834..938
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1116
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1117..1255
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1256..1359
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..1602
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1603..1902
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1903..2063
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            2064..2197
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            2198..3920
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3573..3578
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /note="hexamer: AATAAA"
     polyA_site      3589
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /note="major polyA site"
ORIGIN      
        1 gacagacaga ggcctgccta ggcctcctgc ctaagcggca tcatgagaga ggaaagggtc
       61 actcccagca gctggcctag gagatagcag cagggaggga gcaggagcca agacacctgc
      121 cagcaggctc acaggaggag tgaggggaat tggcttttca gaggctttaa accaacagaa
      181 gtccaccatc ttcgccagtg tggagataga tctagagaga gaacacagaa gcgacagtgt
      241 gaggtcagca cttcctgggc tgtggattcc agtagcctgc agccatgggg caagctctga
      301 gcatcaagag ctgtgacttc cacgcagcag aaaacaacga ggagcactac accaaggcca
      361 tcagctccca gcaccttact ttgaggaggg gacagtcctt cactatcacc ctgaacttcc
      421 gtgctccaac ccacacattt ctgtctgccc tgaagaaagt ggctctcatt gcacaaacgg
      481 gagagcaacc ttccaagatc aataagaccc aagccatctt cccaatttcc tctcttgggg
      541 accaaaaagg gtggagtgca gcagtggagg aaagagatgc ccaacactgg accgtctctg
      601 tgaccacacc tgtggatgct gtcattggcc actactcact cttgcttcag gtttcaggaa
      661 agaaacaata ccccttgggc caattcacac tgctctttaa tccatggaac agagatgatg
      721 ctgtatttct acagaacgag gctgaacgca cagaatatgt gttgaaccag aacggcttta
      781 tctacctggg cacagctgac tgcattcagg aagagccctg ggactttggt cagtttgaga
      841 aagacgtcat ggacctcagc ctgaagttac tgagtatgga caagcaagtg aaagactgga
      901 accagcctgc acacgtggcc cgagttgtgg gcgccttgtt gcatgccctc aagaagaaga
      961 gtgtcctgcc tatttcacag acccaggctg cccaggaagg tgccttgttg tacaaacgtc
     1021 ggggcagcgt gcccatcctg aggcagtggc tcactggcca aggacgagcc gtgtatgaga
     1081 cccaggcgtg ggtgtctgct gctgttgctt gcacagtgct acggtgcctg ggcatcccag
     1141 ctcgagtcgt taccacattt gattcagccc aaggtacagt tgggagcctg ctggtggatg
     1201 agtactacaa tgaggaggga ctccagaatg gagaaggaca gaggggccat atctgggtct
     1261 tccaaacgtc tgtagaatgc tggatgaaca gacctgattt gtcccaaggt tatggtggat
     1321 ggcagattct gcacccaagg gctcctaatg gagctggagt cctgggatcc tgcagtctgg
     1381 tcccagtcag agcagtcaag gagggggaac tgcagctgga ccccgcagta ccagagctct
     1441 ttgcagcagt aaatgcctcg tgtgtggtct ggaagtgctg tgaggatggg aagttggagt
     1501 tgaccaactc caacagaaaa gatgtgggca actgcatcag caccaaggtg gtgggcagtg
     1561 accgctgtga agacatcact cagaactaca agtatcctgc aggatctctt caagaaaagg
     1621 aggtactgga gaaagtccaa aaagaaagac tgaagcttgg gaaagacaac ggcatgtgtc
     1681 ctcccagttg tgagccctgg gatcctctac acatgttctt cgaagcatct agctccatcc
     1741 ctctgagtgg agatggtcag ctctcagtga ccttgattaa ccccacagac gaggagaaga
     1801 aggtgcacct ggtgattggg gcccaggctt tgtactacaa tggagtcctc gctgctggtc
     1861 tctggagcaa gaagcagttg ttcatgctca aacccaacca ggtgatgaga ctatccacca
     1921 acctgtcctt ctcctgtttt gagcaaaccc cacccgagaa cagctttctc cgagtcacgg
     1981 caatggcaag gtactcccac accagcctca gctgctttgc ccaggaaaat atggccattg
     2041 gtaaaccgga tcttatcatc gagatgccaa agagagcagc acagtatcgg cccctcactg
     2101 tctccgttag aatgcacaac tccttagagg cccccatgca gaactgcatc atctccatct
     2161 ttggaagggg actcattcac agagagaaga gatatggatt gggttctctg tggccaggaa
     2221 gcagcctaca tactcagttc cagttcaccc caacacatct ggggctccaa aggctcactg
     2281 tggaagtaga ttgtgacatg ttccagaacc tgaccggcta cagaagtgtc cttgtggtgg
     2341 cccctgaagt ttctgtttaa ctcccaaaca accctcaacc gtctaaaact agacatgctc
     2401 cagaggggaa ttctgcctac caagcaacag accagtggcc aaaaatcagc tagattcaca
     2461 gaaaccaaaa tccatttttt ttccttgttt tttggttatt tggttggttg gttggttggt
     2521 atttttgaga cagggtttct ctatgtagtg ctgttggtcc aggaactcac tctgtagatc
     2581 acactggcct tgaactcaga gatccacctg cctctgcctc ccaagtactg ggattaaagg
     2641 cgtgcgccac cactgcctgg ctccaaaatc catttgtatc aagccaacct aaggcagtca
     2701 gaaacactat ttgtcttaga ctaaactgca taagtgataa aaacaagcct ttgaaaagac
     2761 actcagataa cttctcaaag tataatgaga tgttctgact accttttcag agtacattca
     2821 gatttggggt gttcagatgt ttcataccat tttattgctc gttaacatat ccattaacct
     2881 acaggaatga aagacaacct aatatttaaa tctatttctg atgacataga acaatattga
     2941 ctaaaaatag aattttcaca taatactaaa attacattga ttaattcttt ccctggtggc
     3001 tattgtaaaa gacccaaaga tgagtggata gagctattat aacacattaa cataggacct
     3061 gaaagaatag actaaactta tctatagcta gatcttcatg agtgctggtg ttttcggggg
     3121 actctattca ggtcatacac cacaccccac tgcagcttta ccctgctttc caacatatga
     3181 tcttctagag cagtggttct cagccttcta atgctgaggt ccattagtac agttcctcgt
     3241 attttggtga cccccaacca taaaattatt ttgttgctac ttcataatta taattttgct
     3301 gttgttatga atcataatgt aaatatctga tattcaggat atatgatatg tgaccatcaa
     3361 agggtttcga aatccatggt tgagaactgt tgttctagat gcacacaaca tataatttca
     3421 tagcaatgta gttggaaaca atgtatcaaa ttttttgtct aaattataaa ttcatgcatt
     3481 tttttgcttt ataaaagtgt gttcacattt gagaatacat gttatattaa acaatgacaa
     3541 gatgggtttg tataaagaaa acaaatcttc ttaataaagt ggacaaagct aacaaatgag
     3601 ctgtggtggt ttgactgaga aattccctaa aggctcataa atgaaaactc ttggtcccta
     3661 gttagtggaa ctgattgaga aggattggga ggtgtggctt gttggaggaa gtgtgttgct
     3721 ggtgggtggg ctttgaagtt tcaaaagccc aagccaggcc cagtgtctct cttcctgcag
     3781 cctgtagatt gagatgtaaa actctcagct acttctccgg gcctatgtct gcctgaatgc
     3841 tgccatgctc cttgtcatga tgactaatgg actaaacctc tgaaactgta agcaagcccc
     3901 aattaaatgc tctctcttat
//
