LOCUS       NM_001368800            8337 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus erythrocyte membrane protein band 4.1 like 1
            (Epb41l1), transcript variant 8, mRNA.
ACCESSION   NM_001368800
VERSION     NM_001368800.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8337)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 8337)
  AUTHORS   Wang,D., Zhang,L., Hu,A., Wang,Y., Liu,Y., Yang,J., Du,N., An,X.,
            Wu,C. and Liu,C.
  TITLE     Loss of 4.1N in epithelial ovarian cancer results in EMT and
            matrix-detached cell death resistance
  JOURNAL   Protein Cell 12 (2), 107-127 (2021)
   PUBMED   32448967
  REMARK    GeneRIF: Loss of 4.1N in epithelial ovarian cancer results in EMT
            and matrix-detached cell death resistance.
REFERENCE   3  (bases 1 to 8337)
  AUTHORS   Wang,H., Parra,M., Conboy,J.G., Hillyer,C.D., Mohandas,N. and An,X.
  TITLE     Selective effects of protein 4.1N deficiency on neuroendocrine and
            reproductive systems
  JOURNAL   Sci Rep 10 (1), 16947 (2020)
   PUBMED   33046791
  REMARK    GeneRIF: Selective effects of protein 4.1N deficiency on
            neuroendocrine and reproductive systems.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8337)
  AUTHORS   Zhang,X., Chen,M.H., Wu,X., Kodani,A., Fan,J., Doan,R., Ozawa,M.,
            Ma,J., Yoshida,N., Reiter,J.F., Black,D.L., Kharchenko,P.V.,
            Sharp,P.A. and Walsh,C.A.
  TITLE     Cell-Type-Specific Alternative Splicing Governs Cell Fate in the
            Developing Cerebral Cortex
  JOURNAL   Cell 166 (5), 1147-1162 (2016)
   PUBMED   27565344
REFERENCE   5  (bases 1 to 8337)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   6  (bases 1 to 8337)
  AUTHORS   Fukatsu,K., Bannai,H., Zhang,S., Nakamura,H., Inoue,T. and
            Mikoshiba,K.
  TITLE     Lateral diffusion of inositol 1,4,5-trisphosphate receptor type 1
            is regulated by actin filaments and 4.1N in neuronal dendrites
  JOURNAL   J Biol Chem 279 (47), 48976-48982 (2004)
   PUBMED   15364918
REFERENCE   7  (bases 1 to 8337)
  AUTHORS   Zhang,S., Mizutani,A., Hisatsune,C., Higo,T., Bannai,H.,
            Nakayama,T., Hattori,M. and Mikoshiba,K.
  TITLE     Protein 4.1N is required for translocation of inositol
            1,4,5-trisphosphate receptor type 1 to the basolateral membrane
            domain in polarized Madin-Darby canine kidney cells
  JOURNAL   J Biol Chem 278 (6), 4048-4056 (2003)
   PUBMED   12444087
REFERENCE   8  (bases 1 to 8337)
  AUTHORS   Walensky,L.D., Blackshaw,S., Liao,D., Watkins,C.C., Weier,H.U.,
            Parra,M., Huganir,R.L., Conboy,J.G., Mohandas,N. and Snyder,S.H.
  TITLE     A novel neuron-enriched homolog of the erythrocyte membrane
            cytoskeletal protein 4.1
  JOURNAL   J Neurosci 19 (15), 6457-6467 (1999)
   PUBMED   10414974
REFERENCE   9  (bases 1 to 8337)
  AUTHORS   Peters,L.L., Weier,H.U., Walensky,L.D., Snyder,S.H., Parra,M.,
            Mohandas,N. and Conboy,J.G.
  TITLE     Four paralogous protein 4.1 genes map to distinct chromosomes in
            mouse and human
  JOURNAL   Genomics 54 (2), 348-350 (1998)
   PUBMED   9828140
REFERENCE   10 (bases 1 to 8337)
  AUTHORS   Takeuchi,K., Kawashima,A., Nagafuchi,A. and Tsukita,S.
  TITLE     Structural diversity of band 4.1 superfamily members
  JOURNAL   J Cell Sci 107 (Pt 7), 1921-1928 (1994)
   PUBMED   7983158
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928935.14 and AL929153.11.
            
            Transcript Variant: This variant (8) encodes the longest isoform
            (f).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164131,
                              SAMN01164132 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-209               AL928935.14        76807-77015
            210-258             AL928935.14        94301-94349
            259-449             AL929153.11        28546-28736
            450-614             AL929153.11        29599-29763
            615-719             AL929153.11        30502-30606
            720-762             AL929153.11        31128-31170
            763-838             AL929153.11        34229-34304
            839-1057            AL929153.11        38287-38505
            1058-1145           AL929153.11        40408-40495
            1146-1298           AL929153.11        40993-41145
            1299-1396           AL929153.11        43455-43552
            1397-1572           AL929153.11        43774-43949
            1573-1718           AL929153.11        45378-45523
            1719-1754           AL929153.11        46427-46462
            1755-1937           AL929153.11        48670-48852
            1938-3860           AL929153.11        55880-57802
            3861-3971           AL929153.11        58303-58413
            3972-4379           AL929153.11        59523-59930
            4380-4484           AL929153.11        61531-61635
            4485-4565           AL929153.11        64032-64112
            4566-4652           AL929153.11        68423-68509
            4653-4736           AL929153.11        69328-69411
            4737-4817           AL929153.11        71622-71702
            4818-4934           AL929153.11        72009-72125
            4935-8337           AL929153.11        74452-77854
FEATURES             Location/Qualifiers
     source          1..8337
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 77.39 cM"
     gene            1..8337
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /note="erythrocyte membrane protein band 4.1 like 1"
                     /db_xref="GeneID:13821"
                     /db_xref="MGI:MGI:103010"
     exon            1..209
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            210..258
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            259..449
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     CDS             273..4943
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /note="isoform f is encoded by transcript variant 8; band
                     4.1-like protein 1; neuronal protein 4.1; erythrocyte
                     protein band 4.1 like 1"
                     /codon_start=1
                     /product="band 4.1-like protein 1 isoform f"
                     /protein_id="NP_001355729.1"
                     /db_xref="CCDS:CCDS89573.1"
                     /db_xref="GeneID:13821"
                     /db_xref="MGI:MGI:103010"
                     /translation="MTTETGPDSEVKKAQEETPQQPEAAAAVTTPVTPAGHSHPETNS
                     NEKHLTQQDTRPAEQSLDMDDKDYSEADGLSERTTPSKAQKSPQKIAKKFKSAICRVT
                     LLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTYCDADSQKNWLDPSKEIKK
                     QIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSY
                     AVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLEN
                     AKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNF
                     YIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSK
                     FRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGEFSRPASVSENHDAGPD
                     GDKREDDAESGGRRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQA
                     SINELKRTLKEPNSKLIHRDRDWDRERRLPSSPASPSPKGTPEKASEGSEHWVLIERV
                     YTRPEDLGLLTVPATQREESGSSLTEILADGRLSKVDILVDKFKVEVATEETVRAQRT
                     STQQQGKMIASPEGSETMREEDACLRGGPRDATRAAGYTSTDKLKLRNTRVSNGQTES
                     HVELNKGLERPQTWGRLTAAGVGPVQGEVLSPASDKGGLQSFLLDPAQTEARADSSDE
                     TDTSFAERSFCLNYGKKDSEDSLLAPSLGDREEHLDAPPGDGTWLELAGAHTENWEPK
                     SSDPRASAPGSSQNKDEAHMASSAEEAWSPRDRGRPDDLQGSAVCQTLEEGWENTQGL
                     EGELAYPVADVAEDEAPTSIDWMGKTEKKSPPARWKKNPPGGGGGGGGGGGGGGGGGG
                     GGGGRVHLDAQACALLRTIPPCVRKPVRPDQASFLPKEKGAVSTHAVEPETEDREAVT
                     PLPASSGHTEVLAATSLSPVPPRSGESSESRGFIRDQSPVILKYIHLPEESPVHKDPQ
                     GERKAPPVASKKPRVVPEGTEGPALLGLVLPSGKLETSLQDRDQGGSQEDVSKTSVAN
                     KIRIFETHGAEPCRASQGEVRTLPHEPPSEASPGQVEERSKPRDLGFVQLQPPGDLAS
                     PKVTCSSVMPLATQHYGEATPTTSHQERCTDPELVSPDSGCETTLEEATGSKAGDAGG
                     EDKNSFGRLAPSTPGKGGRLRFASPPGLQRAGLREGSEEKVKPPRPRAPESDTGDEDQ
                     DQERDAVFLKDNHLAIERKCSSITVSSTSSLEAEVDFTVIGDYHGGAFEDFSRSLPEL
                     DRDKSDSETEGLVFARDLKGPSSQEDESGGLEDSPDRGACSTPEMPQFESVKAETMTV
                     SSLAIRKKIEPEAMLQSRVSAADSTQVDGGTPMVKDFMTTPPCITTETISTTMENSLK
                     SGKGAAAMIPGPQTVATEIRSLSPIIGKDVLTSTYGATAETLSTSTTTHVTKTVKGGF
                     SETRIEKRIIITGDEDVDQDQALALAIKEAKLQHPDMLVTKAVVYRETDPSPEERDKK
                     PQES"
     exon            450..614
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            615..719
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            720..762
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            763..838
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            839..1057
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1145
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1146..1298
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1396
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1397..1572
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1573..1718
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1719..1754
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1755..1937
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1938..3860
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            3861..3971
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            3972..4379
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            4380..4484
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            4485..4565
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            4566..4652
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            4653..4736
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            4737..4817
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            4818..4934
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            4935..8337
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5927..5932
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /note="hexamer: ATTAAA"
     regulatory      5932..5937
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /note="hexamer: AATAAA"
     polyA_site      5937
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /note="major polyA site"
     polyA_site      5974
                     /gene="Epb41l1"
                     /gene_synonym="4.1N; Epb4.1l1; mKIAA0338; NBL1"
                     /note="major polyA site"
ORIGIN      
        1 gcatttctgc gcagctccgg agcgtcttgg agcctgcctg ggcggccact ggacgaaggg
       61 actcagagac agacagacag acggctcccg gaagccgcgc cgccgccgcc aggttagcag
      121 ggcgcggaga ccgagcaggc tgttgctacg tcccgagctc gcgtgctgga ggacgtgcgt
      181 ggccgaagct acgattcgtg tctttgcggg tgcctggctg aggacgtcct ccccagggag
      241 ccggtgtgcc gaggaggggc gtgctggtca ccatgacaac agagacaggt cccgattctg
      301 aggtgaagaa ggctcaggag gagactccac agcagcccga ggctgccgca gctgtgacca
      361 ccccggtgac ccccgcgggc cacagccacc cagagaccaa ttccaatgag aagcatctga
      421 cccagcagga cacgaggcct gctgaacaga gcctggatat ggacgataag gattacagtg
      481 aggccgatgg cctgtcggag aggaccacgc ccagtaaggc ccagaagtca cctcagaaga
      541 ttgccaagaa gttcaagagt gccatatgcc gcgtcaccct gctcgatgct tctgagtatg
      601 agtgtgaagt ggagaagcac ggccggggcc aggtgctgtt tgacctggtc tgtgagcacc
      661 ttaacctcct ggagaaggac tacttcggtc tgacctactg tgatgctgac agccagaaga
      721 attggctgga cccctccaag gaaatcaaga agcagatccg gagtagcccc tggaactttg
      781 ccttcacagt caagttctac cctcctgacc cagctcagct gacagaagac atcacaaggt
      841 actacctgtg cctgcagctg agggcagaca ttatcacagg ccgcctgcct tgctcctttg
      901 tcacgcatgc ccttctgggc tcctacgctg tgcaggctga actgggtgac tatgatgccg
      961 aggaacacgt gggcaactat gtcagtgagc tccgcttcgc cccaaaccag acccgggagc
     1021 tggaggagag gatcatggag ttgcataaga catacagggg catgaccccg ggcgaggcag
     1081 agatccactt cctggagaac gccaagaagc tctccatgta tggagttgac ctgcatcacg
     1141 ctaaggattc tgagggcatc gatatcatgc taggtgtctg tgccaatggc ctgctcatct
     1201 accgggaccg cctgagaatc aaccgctttg cctggcccaa gattctcaag atctcctaca
     1261 agaggagtaa cttctacatc aagatccggc ctggggagta tgagcagttt gagagcacca
     1321 tcggcttcaa gctccctaac caccgctcag ccaagcggtt gtggaaggtc tgcatcgagc
     1381 accacacgtt cttccggctg gtgtcaccgg agcccccacc caagggcttt ctggtgatgg
     1441 gctccaagtt ccggtacagt gggaggacgc aggcccagac ccgccaagcc agtgccctta
     1501 tcgaccgacc cgcccccttc tttgaacgtt cttccagcaa acgctatacc atgtcccgca
     1561 gccttgatgg agagttctcc cgccctgcct cagtcagtga gaatcacgat gcagggcctg
     1621 acggtgacaa gcgggaagat gacgccgagt cagggggacg ccgatcagag gctgaagaag
     1681 gagaggtcag gacacccacc aagatcaagg agctgaagcc ggagcaggaa accacgccac
     1741 gacacaagca ggagttcctg gacaagccag aggatgtctt gttgaagcac caggccagca
     1801 tcaatgaact caagaggacc ctgaaggagc ccaacagcaa actgatccac cgggatcgag
     1861 actgggatcg ggagcgcagg ctgccctcgt cgcctgcctc cccctccccc aagggcaccc
     1921 cggaaaaagc cagtgagggc tcagagcatt gggtattgat agaaagagtt tacactaggc
     1981 cggaagacct tggcctcctc acagtgcccg ccacacaacg ggaagaaagt ggatcaagcc
     2041 tcaccgagat cctcgctgat gggagactct ccaaggtaga cattctggtg gacaagttca
     2101 aagttgaagt ggccacagaa gaaaccgtga gagcccaaag aacaagtact cagcagcaag
     2161 ggaaaatgat tgcaagtcca gaaggctcag agacaatgag agaggaagat gcgtgcctca
     2221 gggggggtcc tagagatgct actcgggctg caggctacac atcaacagac aagctcaagc
     2281 tcaggaacac ccgagtctca aatggtcaaa cagagagcca cgtagaattg aacaagggtc
     2341 tggagaggcc ccagacctgg ggaagactga cggctgcggg ggttgggcca gtgcagggag
     2401 aggttctttc tcctgcatca gacaaagggg gactccagtc cttcctgttg gatccagcgc
     2461 aaacagaagc cagagctgac tcgagtgacg agactgacac ctccttcgca gagaggagct
     2521 tctgtctgaa ctacggaaag aaagactctg aggactccct tcttgcccca tccttagggg
     2581 acagagaaga gcacctggat gcccctcctg gagatgggac ctggctggag ctggctgggg
     2641 cgcacacaga gaactgggag ccgaagtcct cagacccaag ggcttctgcc ccgggttcca
     2701 gccagaataa agatgaagcc catatggctt cctcagcaga agaagcctgg tcccccaggg
     2761 accgtggaag acctgatgat ctgcagggat cagctgtctg tcagactctg gaagagggct
     2821 gggaaaacac acaagggctg gaaggagagt tggcctaccc agtggccgat gtagctgaag
     2881 atgaggcccc cacgagtata gattggatgg gaaagactga aaaaaaaagt cctccggcaa
     2941 gatggaagaa gaaccctcct ggaggaggag gaggaggagg aggaggagga ggaggaggag
     3001 gaggaggagg aggaggagga ggaggaaggg tgcacctaga tgctcaggcg tgtgcccttc
     3061 tgaggaccat ccctccctgt gttaggaagc cagtcaggcc agaccaagcc agcttcctgc
     3121 ctaaagagaa gggggcagtt tccactcatg cagtagaacc tgagacagaa gacagggagg
     3181 cagtcacgcc cctgccagcc tcctctggtc acactgaggt cctggcagcc acttctctaa
     3241 gcccagtccc tcctagatca ggggagtctt cggagtccag gggtttcatt agagatcagt
     3301 cccccgtgat tcttaagtat atccatctcc ctgaagagag tccagtgcac aaggacccgc
     3361 aaggtgagcg caaagcacct ccagtggcca gcaagaagcc cagagttgtc cctgaaggaa
     3421 ccgaggggcc tgccctcctg gggttggtgc tcccttcagg aaagctggag acttcactcc
     3481 aggataggga ccaaggaggt tcccaggaag acgttagcaa gacctcagtg gctaacaaaa
     3541 ttcggatatt tgagacccat ggagccgagc cttgcagagc cagtcagggt gaagtgagga
     3601 cccttccaca tgagccgcct tcggaagcgt ccccaggaca ggtggaggag cgcagtaagc
     3661 ctcgggactt gggctttgtc caactccagc ctcctgggga cttggccagc cccaaagtta
     3721 cctgttcttc tgtcatgcct ctggctaccc agcactatgg ggaggccacc ccaactacct
     3781 cccaccagga aagatgcaca gacccagagc tcgtgtcccc tgactcaggc tgtgaaacca
     3841 cgctggagga agctactggg agcaaagccg gagatgcggg cggggaagac aagaactcct
     3901 tcggccgctt agcgccaagc acccctggga agggggggcg tctgagattc gccagccctc
     3961 cgggccttca gagagcaggg ctgagggagg gctcagagga gaaagtcaaa ccaccacgcc
     4021 cacgtgcccc agagagcgac acgggagatg aggaccagga ccaggagagg gacgccgtat
     4081 tcctgaagga caaccacctg gccattgagc gcaagtgctc cagcattacg gtcagctcca
     4141 cgtccagcct ggaggctgag gtggacttca cggttattgg tgactaccat ggcggcgcct
     4201 ttgaagactt ctcccgaagc ctccctgagc ttgatcggga taaaagtgac tctgagacag
     4261 agggcctggt gttcgcccgg gatctcaagg ggccctccag ccaagaggat gaatctgggg
     4321 gcctcgagga cagcccggat cgaggggcct gttccactcc agaaatgccc cagtttgagt
     4381 ctgtgaaagc agaaaccatg accgtcagca gtctggcaat caggaagaag attgagccag
     4441 aggccatgct gcaaagcaga gtctccgctg cagacagcac ccaggttgat gggggtactc
     4501 caatggtgaa agacttcatg acaactcccc cctgcatcac cacagagacc atctcaacca
     4561 ccatggagaa cagtctcaag tccgggaagg gggcagctgc catgatccca ggcccacaga
     4621 cggtggccac ggaaatccgt tctctttcac cgatcatcgg gaaagatgtc ctcaccagca
     4681 cgtacggcgc caccgcggaa accctctcaa cctctaccac cacccatgtc accaaaactg
     4741 tgaagggagg gttttctgag acaaggatcg aaaagcgaat catcattact ggggatgaag
     4801 atgtcgatca agaccaggcc ctggctttgg ccatcaagga agccaaacta cagcatccag
     4861 acatgctggt aaccaaagct gttgtctata gagaaacaga cccatccccg gaggagagag
     4921 acaagaagcc acaggaatcc tgacctctgt gaagagatgc tggcgtgtct ggtccaaccc
     4981 aagccagaga gccattaaga aggggccttc actctggatt ctccgacaat accaacatcc
     5041 cagctgcgac gtactgtcac tgaagagaga ctgggaaggg aaagcatata tatatagata
     5101 tatagagata tagatatata tacaggaaac accgcgtcct tgcaccgctg ctggggctgg
     5161 cggagcagtc agctgatggc cacgaccaac atctgcaaca accttcattt cctttgcaga
     5221 caaatcgaat tggtgggaat tttttttcag gaaaatgtat aacaatcata atctctcact
     5281 ccccaaaccc cttctcctgc aaactaaaaa agcagaccgc catgattgta gacattccct
     5341 tgaaccccag ctgcacagac tccaggatgg acgagcaccc cgtttgttct ccagcctctg
     5401 ttgctccctc taatgcaaag gaagaaagaa attagatcac ggagccaagg aagagaagtc
     5461 acagcagcaa gacacgcacg gttggctatt tgccaagaaa gaatggaagt ctcccccatg
     5521 gagaggagga ggaggaggag gaggaggagg aggaggagga ggaggaggag gaggaggagg
     5581 aacgctcagt tgttcctttc tgggtcttga cactgggctg caaaatccct tctctgttct
     5641 tctgcctccc cgcttcaccc ttgacctcta ctcatcctgt cttcatattc tgtctcagct
     5701 cccctctgcc tctctcccaa ccctcctgtt ctgtgtcctg gtcctgctga gggccactgc
     5761 aggtaactct cattggaaga aaaagaaact acaagagcaa acagaagcca tgggaaggga
     5821 agtagacact gtgtgcttcc ggtttctcat gacggaggtg cagcttgtag gagattatat
     5881 gactgtgatt ttaagttatg tatattacat gtaacaggaa acaaatatta aaataaactg
     5941 tgctggtaag tatgcagctg acatttccaa gttataatta cctgactgtg attgatgtat
     6001 cctaaggttc ctagatcttg ccaaactggc ccagctgaga acactggact ctgggtgtgg
     6061 ccagctccca gtagggctga cagattcagt gtagtgaaac tgtgtgtggt gtttgtaact
     6121 gggtgattgg tggggagagt ggagaagccc tccgtgaaga ggtgagggtt ccggccagaa
     6181 gggagcaaca cagatgtcat cccgaatatg ccaggccaaa atgccttctt ccccagcagt
     6241 agctgccagg gcctggtctg tgctcaggac actactgctg aggttctgta ggtcagtcct
     6301 cctacctcca gggggctcgc cttggttttc ggtcctctct ctctctctct ctctctctgt
     6361 ttcctattac cagggtcttt gtttgggttt gtgctcggcc atgtcttgct ctgctcctca
     6421 gcacctcatc acaatgagtt ctttaaaggg aggtggggtc ctagctaagg tggagaacag
     6481 cgactctaac ctggttttct gaaatgccca gccagccttt cccctctgcc tctgtctgtc
     6541 ttgtgaatca tcctcttctt cctgagctaa agtagccacg ataaagaggc catgagcaca
     6601 gggaaggcca caataggccc atgctgcatt tccaaaagcc tcagccatcc ctaaactaga
     6661 gcaggcttga ggaagtgttg ccatccggct ccatctgcat cagaccctgg cttgcaggac
     6721 ctccatcagt cagtatctaa gctcagaaat ggccttgagg tgacaggagc ccttggagaa
     6781 aacgctgcca caggctgcta tttcggcctg gcacatacag gcttcctctg gcttgctctc
     6841 aatgtctctc cctttctgag tgaaagtatc ccacggcagt cccatctcac ttcctgtcct
     6901 gctaaggcac ttcatacatt tagtcaacag atgtttacca gtttcctgct tgtgtcaggc
     6961 tctgttttca aggcagaagg agagggaggg acctgggaag ccactggaca agcctgtctg
     7021 tccctatcca tagctggctc ttttcagtac ccttcttcac gccctccacc tgatgagaca
     7081 gtcccgtgaa atgtctccgg gagagccccg gctggatgtg ttctcttggc ttgcttcttg
     7141 gttactcttg tgatgtacac cttccctact cacaggtgct ggcctgacac agggcaagaa
     7201 gctaggagag cttctgtctc tgtggcagct gagacgagcc aagctcttag ataacagagc
     7261 cagccatatg cccccggtgc aggctggtag gcctgccctg ctccagtggg gcagcacatt
     7321 gtctctgctc caggatcttt ggccattctt gatggagaag ccacagaacc tccctcctgc
     7381 tcctcacggc atgcaagctc ccactgcttc tctgagcccg gagcaggaac ggctctatca
     7441 ccttggaatc aggctcgggc ctcacctact tttgcaggaa ctccccggcc tgaacacaca
     7501 agacatacat acctcagagg gagcctcatt gtacctgctc tgaatgtggg ctacagggca
     7561 aggacgaaat gacccagctt agctcgtggg acattagggt ttggggagat acttactcca
     7621 tggatgttct gaccggttct tactattttt ttttctccca gagaggcagt cagtaccccg
     7681 cccagggagg aggagacctg cacagctaaa atctagggca ccgtctcctc cccctcctcc
     7741 acttcataga gaataaggac gttgtgttgt ctgacttcag cctacttttt ccttttgctt
     7801 tttttgtgtg tctgtctcat catctctgtg gcacctcgct ctccaggggg ccaggtaaca
     7861 gtgagaaaag ccacctagag cagtcagggt tccaggtgag catctcaatg cagctcctaa
     7921 ctcaccgtgt gacactgggc tgtcccattt cacataactc aaaggacagg gcaagcatta
     7981 caccctgagc ctctttccca ttctgtgtct catgcgcctt tgttttcccc acgtttgctt
     8041 tctgtgaatc ttttccacac gagggcagag gaagtgccag gagctgtttc agtttctgaa
     8101 tcctgcaagc acataccaag actggcctga aattgcatga gcaacatcac tctagatatc
     8161 tatttttttt tcaaaagcac cttagcagcc acctgcaatg ctgtcctgtt ccttttctcc
     8221 cagtcccctc tctcctctct cgtccccacg cttccccacc tcagtgctcc gtgctgtatg
     8281 cgtgtgctct ctgttcttgt ataatcaata aaagtgaaat aaatgtgttt gatgctg
//
