LOCUS       NM_001014995            3143 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus endosomal transmembrane epsin interactor 3 (Entrep3),
            transcript variant 1, mRNA.
ACCESSION   NM_001014995 XM_619921
VERSION     NM_001014995.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3143)
  AUTHORS   Zhang,H., Huang,C.J., Tian,Y., Wang,Y.P., Han,Z.G. and Li,X.C.
  TITLE     Ectopic overexpression of COTE1 promotes cellular invasion of
            hepatocellular carcinoma
  JOURNAL   Asian Pac J Cancer Prev 13 (11), 5799-5804 (2012)
   PUBMED   23317259
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161600.6 and BC088990.1.
            
            On Sep 27, 2017 this sequence version replaced NM_001014995.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088990.1, SRR7345562.3138727.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-82                AC161600.6         176935-177016
            83-3141             BC088990.1         1-3059
            3142-3143           AC161600.6         183082-183083
FEATURES             Location/Qualifiers
     source          1..3143
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 39.01 cM"
     gene            1..3143
                     /gene="Entrep3"
                     /gene_synonym="1110013L07Rik; Fam189b"
                     /note="endosomal transmembrane epsin interactor 3"
                     /db_xref="GeneID:68521"
                     /db_xref="MGI:MGI:1915771"
     exon            1..806
                     /gene="Entrep3"
                     /gene_synonym="1110013L07Rik; Fam189b"
                     /inference="alignment:Splign:2.1.0"
     CDS             582..2591
                     /gene="Entrep3"
                     /gene_synonym="1110013L07Rik; Fam189b"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein FAM189B; family with sequence similarity 189,
                     member B; protein ENTREP3"
                     /codon_start=1
                     /product="protein ENTREP3 isoform 1"
                     /protein_id="NP_001014995.1"
                     /db_xref="CCDS:CCDS17492.1"
                     /db_xref="GeneID:68521"
                     /db_xref="MGI:MGI:1915771"
                     /translation="MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLAQVLL
                     GILVITFSMVASSVTTTESIKRSCPSWAGFSLAFSGLVGIVSWKRPFTLVISFFSLLS
                     VLCVMLSMAGSVLSCKNAQLARDFRECSMEGKVCVCCPPIPLHRPCPEWGQELKVALN
                     STCDEARGALKNLLFSVCGLTICAAIICTLSAIVCCVQIFSLDLVHMQLAPERSVSGP
                     LGPLACTSSPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSP
                     VPLYPTDCPPSYEAVMGLRRDSQATLFDPQLHDGSCVCERVASIVDVSMDSGSLVLSA
                     IGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRAGYCLSLDCGLRGPFEDSPL
                     PRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGSR
                     SAAPPPARAPARRFSDSSGSLTPPGHRPPHRTPPPPLLLPRSHSDPGITTSSDIADFR
                     DLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPL
                     PSGPTPAHSLGDLKGSWPGRGLVTRFLQLSRRSPDPTGTGAHGYKQVRRSPWGRPGRE
                     SLHLRSCGDLSSGSSLRRLLSARRLEHGIRPHSLSLNGGSRETGL"
     exon            807..863
                     /gene="Entrep3"
                     /gene_synonym="1110013L07Rik; Fam189b"
                     /inference="alignment:Splign:2.1.0"
     exon            864..974
                     /gene="Entrep3"
                     /gene_synonym="1110013L07Rik; Fam189b"
                     /inference="alignment:Splign:2.1.0"
     exon            975..1094
                     /gene="Entrep3"
                     /gene_synonym="1110013L07Rik; Fam189b"
                     /inference="alignment:Splign:2.1.0"
     exon            1095..1202
                     /gene="Entrep3"
                     /gene_synonym="1110013L07Rik; Fam189b"
                     /inference="alignment:Splign:2.1.0"
     exon            1203..1378
                     /gene="Entrep3"
                     /gene_synonym="1110013L07Rik; Fam189b"
                     /inference="alignment:Splign:2.1.0"
     exon            1379..1478
                     /gene="Entrep3"
                     /gene_synonym="1110013L07Rik; Fam189b"
                     /inference="alignment:Splign:2.1.0"
     exon            1479..1548
                     /gene="Entrep3"
                     /gene_synonym="1110013L07Rik; Fam189b"
                     /inference="alignment:Splign:2.1.0"
     exon            1549..2094
                     /gene="Entrep3"
                     /gene_synonym="1110013L07Rik; Fam189b"
                     /inference="alignment:Splign:2.1.0"
     exon            2095..2163
                     /gene="Entrep3"
                     /gene_synonym="1110013L07Rik; Fam189b"
                     /inference="alignment:Splign:2.1.0"
     exon            2164..2417
                     /gene="Entrep3"
                     /gene_synonym="1110013L07Rik; Fam189b"
                     /inference="alignment:Splign:2.1.0"
     exon            2418..3143
                     /gene="Entrep3"
                     /gene_synonym="1110013L07Rik; Fam189b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3119..3124
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Entrep3"
                     /gene_synonym="1110013L07Rik; Fam189b"
                     /note="hexamer: AATAAA"
     polyA_site      3141
                     /gene="Entrep3"
                     /gene_synonym="1110013L07Rik; Fam189b"
                     /note="major polyA site"
ORIGIN      
        1 ccacgcacca tccaccatcc cccacctcca caggctgacc tgctgcagct ggaggagcta
       61 aggaagccga gcatggtggg gaggggagcg ggtctgcgac tctggagaca gtttccacgg
      121 cctctcccca ccaggcggcc ctgaatggcc aaacgcacct ctagttcctg catgcagacc
      181 ttccccctct ctgtagactt gtttgcatcc ctctcgcttt tgccctcccc acccttgcct
      241 gggttccgga acgctactct tcagtctggg atcagccctt ctcggcaccc ctcttcatta
      301 aggaaatgca atgaaccggt gccctcgcgt cctcatcgcc tccccgggca cggtacccgt
      361 ttggtggtgg ggagggagcc cctcactgtc ccttcgtgac gcccctcctt tgggcctcct
      421 tccagctggc gtccctgggc gatgccccag aggacctagc caggaggtgg gctttacagc
      481 gagggctgtg gaaaggataa agaaccaggg cttgggtgct tctgagatgc tcacaagtat
      541 caagggggac cgagcgaggt gcgagcaact gggcggcagg catgatgccc tcgcccagtg
      601 actccagtcg ctcgctgacc agccggccca gtacccgggg ccttacccac ctccgcctcc
      661 accgaccctg gctccaggcc ctgctcacgt tggggctggc ccaggtgctc ttgggcatcc
      721 tggtgataac cttcagcatg gtggcctcct ctgtcaccac caccgagagc atcaagaggt
      781 cctgcccatc ttgggctggg ttctcgctgg cgttctccgg gttggttggc attgtgtcct
      841 ggaagcggcc attcactcta gtgatctctt tcttctcctt gctttcggtg ctctgtgtca
      901 tgcttagcat ggctggctct gttctctcct gtaagaatgc tcagctggct cgggacttcc
      961 gagagtgctc catggaaggg aaggtctgtg tatgctgccc acctatcccc ctacacagac
     1021 cttgcccaga atggggccag gagctgaaag ttgccctcaa ctccacctgt gatgaagcca
     1081 gaggggccct caagaacctg ctcttcagtg tctgtggcct taccatttgt gctgcaataa
     1141 tctgtaccct ctctgctatt gtctgctgtg tccagatctt ctccctggat ctggtgcata
     1201 tgcagcttgc ccctgaacgg tcagtctcag gccccctagg gcccctggcg tgtacatcct
     1261 cgcctccagc tcctctccta cacaccatgc tggacttgga ggaatttgtc ccgcctgtgc
     1321 ccccaccacc ctactaccct ccagagtaca cctgcagttc agagacagat gcacaaagca
     1381 tcacgtataa tggctccatg gatagcccag tgcccttgta tcctactgac tgcccccctt
     1441 cttacgaggc cgtcatgggg ctgcgaagag acagccaggc cactctgttt gaccctcagc
     1501 ttcacgatgg ctcctgtgtc tgtgagcggg tggcctccat tgtggacgtg tccatggaca
     1561 gtgggtccct ggtgttgtct gccattggcg acctccccgg gggctctagc ccatcagaag
     1621 actcatgcct gctggaactc cagggctctg tgcgctccgt cgattatgtg ctcttccgct
     1681 ccatccagcg cagccgcgca ggctactgcc ttagcctgga ctgcggcctc cggggtccct
     1741 ttgaagacag tcccttgcca aggcgacccc cacgggctgc ccgctcctat tcctgctcag
     1801 cccctgaagc cccaccccca ctgggtgccc ccacagctgc tcgcagttgc caccggttag
     1861 aaggctggcc gccctgggtg ggaccttgtt tccccgagct gaggcggcgg gtcccccgag
     1921 gaggcagccg ctcagctgca ccccctcctg cccgagcacc agctcgacgc ttcagtgata
     1981 gctcaggttc cctcacccca cccggacacc gacctcctca ccggacacct cctccaccac
     2041 tgctgctgcc caggtctcac agcgaccctg gcattaccac ctccagcgac atcgctgact
     2101 tcagggacct ttataccaaa gtgcttgagg aagaagctgc ctctgtctcc tctgcagaca
     2161 cagggctctg ctctgaagcc tgccttttcc gtctagcccg ctgcccttcc cccaagttgc
     2221 tacgtgctcg ctcagccgag aaacgccgcc cagtgcccac cttccagaag gttcccctgc
     2281 cttcaggtcc tacacctgcc cactctctag gggacctgaa aggaagctgg ccaggccggg
     2341 gcctagtcac tcgtttcctc cagctgtcta ggaggtctcc agaccctaca ggaactggag
     2401 cccatggata taagcaagtg cgcaggagcc catgggggcg accaggtcga gagagcctcc
     2461 accttcgcag ctgtggtgat ttgagctctg gctcctccct aaggcgactc ttgtctgccc
     2521 gcaggctaga gcatggcatc cgcccacaca gcctcagcct caatggaggc agccgggaga
     2581 ctgggctctg atttgggcat gttacactga acagatcaga gcaatgctgg agcccataag
     2641 cattagctgg ttaggaccag cagccttcag cagccctgtg caccactggc tggctcaaaa
     2701 agaaatccgc tctatactct cccaaggtgt tcctttcctg cctgcctttg agggctcctg
     2761 ttgcttgcct ctgcctctct gaagggcaga gcttctgtcc tgtgctgcat gggtgtggga
     2821 ggaaatgccc cctgcttaca gcattgacag aggaaaatta gtaacctccc ccccgcatga
     2881 gagtgcctct ttctgatatt ccagggcact gtatgggggc aaaagcctga gtgtttaaga
     2941 acacggcgat ttgtgccttg ccaagcggtg gtagggcagg caaaaagaga catgaatcta
     3001 ggtggctttt cagctttgcc acctctagct gcatgacctc aggcaagtta tttaacctta
     3061 attgcctgac ctgtaaaaca ttgtgaacat gaatgtttgt aacactgagt aagccttcaa
     3121 taaatttcct tttctccctt ctc
//
