LOCUS       NM_001114174            2565 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus endosomal transmembrane epsin interactor 1 (Entrep1),
            mRNA.
ACCESSION   NM_001114174 XM_355152 XM_912427
VERSION     NM_001114174.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2565)
  AUTHORS   Yang,J., Rajan,S.S., Friedrich,M.J., Lan,G., Zou,X., Ponstingl,H.,
            Garyfallos,D.A., Liu,P., Bradley,A. and Metzakopian,E.
  TITLE     Genome-Scale CRISPRa Screen Identifies Novel Factors for Cellular
            Reprogramming
  JOURNAL   Stem Cell Reports 12 (4), 757-771 (2019)
   PUBMED   30905739
REFERENCE   2  (bases 1 to 2565)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   3  (bases 1 to 2565)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY718707.1, AC140378.2, BE994985.1, DV650276.1, DV649334.1,
            BC099492.1, CK624738.1 and BQ032571.1.
            
            On or before Feb 3, 2008 this sequence version replaced
            XM_912427.3, XM_355152.6.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849382
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-71                BY718707.1         1-71
            72-207              AC140378.2         151448-151583       c
            208-677             BE994985.1         1-470
            678-1071            DV650276.1         77-470
            1072-1631           DV649334.1         167-726
            1632-1944           BC099492.1         756-1068
            1945-2541           CK624738.1         37-633              c
            2542-2565           BQ032571.1         1-24                c
FEATURES             Location/Qualifiers
     source          1..2565
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 19.0 cM"
     gene            1..2565
                     /gene="Entrep1"
                     /gene_synonym="Fam189a2; Gm967"
                     /note="endosomal transmembrane epsin interactor 1"
                     /db_xref="GeneID:381217"
                     /db_xref="MGI:MGI:2685813"
     exon            1..472
                     /gene="Entrep1"
                     /gene_synonym="Fam189a2; Gm967"
                     /inference="alignment:Splign:2.1.0"
     CDS             83..1873
                     /gene="Entrep1"
                     /gene_synonym="Fam189a2; Gm967"
                     /note="protein FAM189A2; family with sequence similarity
                     189, member A2"
                     /codon_start=1
                     /product="endosomal transmembrane epsin interactor 1"
                     /protein_id="NP_001107646.1"
                     /db_xref="CCDS:CCDS50408.1"
                     /db_xref="GeneID:381217"
                     /db_xref="MGI:MGI:2685813"
                     /translation="MSLPVVLPGSCCPVAGLSGGPQAGGPGAATAAAAQEPPLPPLRP
                     RWPRGALQPPARPRCAPAAVLAPPPALASRRPAAPGSALLPARPLLSLGLLQLILGCC
                     MVALSFGALSLSSSPQVKNSCPFWAGSSVILSGIIGLTTWKRPMILLVNLFVLLSVVC
                     ILLNLAGFILGCQGAQFVSSVPRCDLVDLGEGKICFCCEEFQPAKCTDKENALKLFPV
                     QPCSAVHLLLKKVLFALCALNALTTTVCLVAAALRYLQIFASRRPCIDESQMSAEDVE
                     EHGRIPDPDDFVPPVPPPSYFATFYSCTPRMNRRMVGSDVIPLPHIYGARIKGVEVFC
                     PLDPPPPYEAVVSQTDQEQESSFQMPEGPETAASPAEPVCTQITQGGALTNTTGEENT
                     SGSTPILTLVQPPRSRRALPLLRTRSKSDPVLHHSEERATPVLSCEAATQTERRLDLA
                     TVTLRRGARPRASRCRPRSLIDYRSYIDTKLLVARFLEQSSCSMTPDIHELVENIKSV
                     LKSDEGHMEEAITSASFLEQIMAPSQPSTSQAQELSWRRQPGLLHLRSCGDLSTFSLT
                     ARPRAERRPQQRAEAERPHSLIGVIRETVL"
     exon            473..529
                     /gene="Entrep1"
                     /gene_synonym="Fam189a2; Gm967"
                     /inference="alignment:Splign:2.1.0"
     exon            530..640
                     /gene="Entrep1"
                     /gene_synonym="Fam189a2; Gm967"
                     /inference="alignment:Splign:2.1.0"
     exon            641..769
                     /gene="Entrep1"
                     /gene_synonym="Fam189a2; Gm967"
                     /inference="alignment:Splign:2.1.0"
     exon            770..877
                     /gene="Entrep1"
                     /gene_synonym="Fam189a2; Gm967"
                     /inference="alignment:Splign:2.1.0"
     exon            878..1011
                     /gene="Entrep1"
                     /gene_synonym="Fam189a2; Gm967"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..1141
                     /gene="Entrep1"
                     /gene_synonym="Fam189a2; Gm967"
                     /inference="alignment:Splign:2.1.0"
     exon            1142..1220
                     /gene="Entrep1"
                     /gene_synonym="Fam189a2; Gm967"
                     /inference="alignment:Splign:2.1.0"
     exon            1221..1373
                     /gene="Entrep1"
                     /gene_synonym="Fam189a2; Gm967"
                     /inference="alignment:Splign:2.1.0"
     exon            1374..1666
                     /gene="Entrep1"
                     /gene_synonym="Fam189a2; Gm967"
                     /inference="alignment:Splign:2.1.0"
     exon            1667..2548
                     /gene="Entrep1"
                     /gene_synonym="Fam189a2; Gm967"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2520..2525
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Entrep1"
                     /gene_synonym="Fam189a2; Gm967"
                     /note="hexamer: AATAAA"
     polyA_site      2541
                     /gene="Entrep1"
                     /gene_synonym="Fam189a2; Gm967"
                     /note="major polyA site"
ORIGIN      
        1 agtccgtcct gcgcggcgcc ggcgcgggtg cccggtgcgc ggcgccctcc gctcggctgc
       61 gccgcccgcc cgccgcgcgc ccatgtctct gccggtggtg ctcccgggct cctgctgccc
      121 ggtggcgggg ctgtcgggcg gacctcaggc cgggggtcct ggcgccgcca ccgccgccgc
      181 cgctcaggag ccgccgctgc ccccgctgcg gccgcgctgg ccccggggtg ctctgcagcc
      241 tccagcccgg ccccgctgcg cccccgccgc cgtgctggcc ccgccgccgg cgctcgcgtc
      301 ccgccgcccc gccgcgccag gctccgcgct gctgcccgcg cgcccgctgc tgtcgctcgg
      361 gctcctgcag ctgatcctgg gctgctgcat ggtggcgctc agcttcgggg cgctgtcgct
      421 gagcagctcg ccgcaggtga agaactcgtg cccattctgg gctggctcct cggtgatact
      481 ctctggaatc attggattga cgacttggaa aaggcccatg atactgctgg tgaatctctt
      541 tgtgctgctc tctgtggttt gcatcctcct aaatctcgca ggcttcatcc taggctgtca
      601 aggagcccag tttgtgtcca gcgtgcccag gtgtgatctg gtggacttag gtgaaggcaa
      661 gatctgcttc tgttgtgaag aatttcaacc agccaaatgc acagacaaag aaaatgcctt
      721 gaaactcttc ccggtccagc cttgtagtgc tgtgcacctt ctgcttaaga aagtcctgtt
      781 tgccctgtgt gccttgaacg ccttgaccac cacagtgtgt ttggtggctg ctgccctgcg
      841 ctacctccag atctttgcca gcagaaggcc atgtattgat gaatcccaga tgtctgcaga
      901 ggacgtggaa gaacacggtc ggattccaga cccagatgac tttgtgccac cagtgcctcc
      961 tccttcttac tttgccacat tttactcctg cacacctcgg atgaaccgca ggatggttgg
     1021 ttctgatgtc atcccactgc cccatatcta tggagcacgc atcaagggtg tggaagtgtt
     1081 ctgtcctctg gaccccccac ctccatacga agctgtagtg agccagactg accaggagca
     1141 ggagtcttca ttccaaatgc cagaaggacc agaaactgct gcgagcccag cagagccagt
     1201 ttgcacgcag ataactcaag gtggggctct tactaacacg actggtgaag aaaacacatc
     1261 tggatcaact cctattctca ctctggttca gcctccgaga agccggagag ctctccccct
     1321 tctgaggaca agatcaaaga gcgaccctgt gcttcaccat tcggaggaga gagctacccc
     1381 ggtgctcagc tgcgaagctg caacgcagac agaaaggagg ctagatctcg ctacagtgac
     1441 tctgaggaga ggcgcgaggc cacgggcatc aagatgcaga ccccgctctc tgatagatta
     1501 caggtcatac atagacacga agctgctagt ggccaggttc ctggagcagt cctcctgcag
     1561 catgactccg gacattcatg aacttgtaga gaacataaag tctgttctga aatccgatga
     1621 ggggcacatg gaagaagcca tcacgagtgc cagtttccta gagcagataa tggccccgtc
     1681 acagcccagc acatcccagg cccaggagtt gagctggagg agacagcccg gcctgctgca
     1741 cctgcgcagc tgtggagatc taagcacctt ctctctgaca gcaaggccga gagccgagag
     1801 gaggccccag cagcgagcgg aggctgagcg gccacacagc cttattggtg tcattcgaga
     1861 gactgtcctg tgaactgagt gacatggaag gatgtccctc ctcagtgctg tttactgtct
     1921 gggagccagg ggcacccctc cccctccccc cactgggaac ccctcaaccg ggttcctggg
     1981 gtgggcactt attcctgttc tttggctccc tttttttgct gacgagggca ctcaggtgaa
     2041 ctcgggtgaa gtacgttctt cctggccctt ccagtctgtg tgttcctggt tggagaagaa
     2101 ggcagggagg gctcctttgt ctgctgggtc tcacagtatc cccaaggggt gcacactggg
     2161 tgagcagaaa gcaggctccc tagcctttgc ctgcctcacc cctcatggct cttgttgttg
     2221 ccaagttcat tcccttgctg taaggggaga gctgccgggc tatttatagc agcctgccgc
     2281 ctctggctgc tcagtgagag gaattggcag gagacatgat ggttaacacc atgtgactcc
     2341 agtcttccag cctcctttag gttaccctca atcccttcct ctttaggaaa agcagcagac
     2401 cagctaagcg gtgttttgtt ttcttttctt ttgttttgtt tttaaatgaa ggacgttaag
     2461 ggtgagcact atggttgagt ccattccttc atgcttgcaa actagaagac agaacagaga
     2521 ataaagcgct ggcgttggaa agtctggaaa aaaaaaaaaa aaaaa
//
