LOCUS       NM_009849               1937 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus ectonucleoside triphosphate diphosphohydrolase 2
            (Entpd2), mRNA.
ACCESSION   NM_009849
VERSION     NM_009849.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1937)
  AUTHORS   Ohmoto,M., Jyotaki,M., Yee,K.K. and Matsumoto,I.
  TITLE     A Transcription Factor Etv1/Er81 Is Involved in the Differentiation
            of Sweet, Umami, and Sodium Taste Cells
  JOURNAL   eNeuro 10 (4) (2023)
   PUBMED   37045597
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1937)
  AUTHORS   Golden,E.J., Larson,E.D., Shechtman,L.A., Trahan,G.D., Gaillard,D.,
            Fellin,T.J., Scott,J.K., Jones,K.L. and Barlow,L.A.
  TITLE     Onset of taste bud cell renewal starts at birth and coincides with
            a shift in SHH function
  JOURNAL   Elife 10, e64013 (2021)
   PUBMED   34009125
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1937)
  AUTHORS   Yu,W., Ishan,M., Yao,Y., Stice,S.L. and Liu,H.X.
  TITLE     SOX10-Cre-Labeled Cells Under the Tongue Epithelium Serve as
            Progenitors for Taste Bud Cells That Are Mainly Type III and
            Keratin 8-Low
  JOURNAL   Stem Cells Dev 29 (10), 638-647 (2020)
   PUBMED   32098606
REFERENCE   4  (bases 1 to 1937)
  AUTHORS   Takai,S., Watanabe,Y., Sanematsu,K., Yoshida,R., Margolskee,R.F.,
            Jiang,P., Atsuta,I., Koyano,K., Ninomiya,Y. and Shigemura,N.
  TITLE     Effects of insulin signaling on mouse taste cell proliferation
  JOURNAL   PLoS One 14 (11), e0225190 (2019)
   PUBMED   31714935
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1937)
  AUTHORS   Fan,D., Chettouh,Z., Consalez,G.G. and Brunet,J.F.
  TITLE     Taste bud formation depends on taste nerves
  JOURNAL   Elife 8, e49226 (2019)
   PUBMED   31570121
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1937)
  AUTHORS   Sevigny,J., Sundberg,C., Braun,N., Guckelberger,O., Csizmadia,E.,
            Qawi,I., Imai,M., Zimmermann,H. and Robson,S.C.
  TITLE     Differential catalytic properties and vascular topography of murine
            nucleoside triphosphate diphosphohydrolase 1 (NTPDase1) and
            NTPDase2 have implications for thromboregulation
  JOURNAL   Blood 99 (8), 2801-2809 (2002)
   PUBMED   11929769
  REMARK    GeneRIF: catalytic properties and vascular topography have
            implications for thromboregulation
REFERENCE   7  (bases 1 to 1937)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
REFERENCE   8  (bases 1 to 1937)
  AUTHORS   Gao,L., Dong,L. and Whitlock,J.P. Jr.
  TITLE     A novel response to dioxin. Induction of ecto-ATPase gene
            expression
  JOURNAL   J Biol Chem 273 (25), 15358-15365 (1998)
   PUBMED   9624117
REFERENCE   9  (bases 1 to 1937)
  AUTHORS   Chadwick,B.P. and Frischauf,A.M.
  TITLE     The CD39-like gene family: identification of three new human
            members (CD39L2, CD39L3, and CD39L4), their murine homologues, and
            a member of the gene family from Drosophila melanogaster
  JOURNAL   Genomics 50 (3), 357-367 (1998)
   PUBMED   9676430
REFERENCE   10 (bases 1 to 1937)
  AUTHORS   Chadwick,B.P. and Frischauf,A.M.
  TITLE     Cloning and mapping of a human and mouse gene with homology to
            ecto-ATPase genes
  JOURNAL   Mamm Genome 8 (9), 668-672 (1997)
   PUBMED   9271669
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY237099.1, AL732557.4, AK002553.1 and BY417293.1.
            
            On Dec 1, 2007 this sequence version replaced NM_009849.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK002553.1, AK172281.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 BY237099.1         2-5
            5-5                 AL732557.4         68651-68651
            6-29                BY237099.1         7-30
            30-1929             AK002553.1         2-1901
            1930-1937           BY417293.1         371-378
FEATURES             Location/Qualifiers
     source          1..1937
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 17.22 cM"
     gene            1..1937
                     /gene="Entpd2"
                     /gene_synonym="Cd39l1; NTPDase2"
                     /note="ectonucleoside triphosphate diphosphohydrolase 2"
                     /db_xref="GeneID:12496"
                     /db_xref="MGI:MGI:1096863"
     exon            1..216
                     /gene="Entpd2"
                     /gene_synonym="Cd39l1; NTPDase2"
                     /inference="alignment:Splign:2.1.0"
     CDS             100..1587
                     /gene="Entpd2"
                     /gene_synonym="Cd39l1; NTPDase2"
                     /EC_number="3.6.1.-"
                     /note="NTPDase 2; ecto-ATPase 2; ecto-ATPDase 2; ecto-ATP
                     diphosphohydrolase 2; CD39 antigen-like 1"
                     /codon_start=1
                     /product="ectonucleoside triphosphate diphosphohydrolase
                     2"
                     /protein_id="NP_033979.2"
                     /db_xref="CCDS:CCDS15770.1"
                     /db_xref="GeneID:12496"
                     /db_xref="MGI:MGI:1096863"
                     /translation="MAGKLVSLVPPLLLAAVGLAGLLLLCVPTQDVREPPALKYGIVL
                     DAGSSHTSMFVYKWPADKENDTGIVGQHSSCDVRGGGISSYANDPSRAGQSLVECLEQ
                     ALRDVPKDRYASTPLYLGATAGMRLLNLTSPEATAKVLEAVTQTLTRYPFDFRGARIL
                     SGQDEGVFGWVTANYLLENFIKYGWVGRWIRPRKGTLGAMDLGGASTQITFETTSPSE
                     DPDNEVHLRLYGQHYRVYTHSFLCYGRDQVLQRLLASALQIHRFHPCWPKGYSTQVLL
                     REVYQSPCTMGQRPQTFNSSATVSLSGTSNAALCRDLVSGLFNISSCPFSQCSFNGVF
                     QPPVAGNFIAFSAFYYTVDFLKTVMGLPVGTLKQLEDATETTCNQTWAELQARVPGQQ
                     TRLPDYCAVAMFIHQLLSRGYRFDERSFRGVVFEKKAADTAVGWALGYMLNLTNLIPA
                     DLPGLRKGTHFSSWVALLLLFTVLILAALVLLLRQVRSAKSPGAL"
     exon            217..334
                     /gene="Entpd2"
                     /gene_synonym="Cd39l1; NTPDase2"
                     /inference="alignment:Splign:2.1.0"
     exon            335..485
                     /gene="Entpd2"
                     /gene_synonym="Cd39l1; NTPDase2"
                     /inference="alignment:Splign:2.1.0"
     exon            486..645
                     /gene="Entpd2"
                     /gene_synonym="Cd39l1; NTPDase2"
                     /inference="alignment:Splign:2.1.0"
     exon            646..873
                     /gene="Entpd2"
                     /gene_synonym="Cd39l1; NTPDase2"
                     /inference="alignment:Splign:2.1.0"
     exon            874..1128
                     /gene="Entpd2"
                     /gene_synonym="Cd39l1; NTPDase2"
                     /inference="alignment:Splign:2.1.0"
     exon            1129..1248
                     /gene="Entpd2"
                     /gene_synonym="Cd39l1; NTPDase2"
                     /inference="alignment:Splign:2.1.0"
     exon            1249..1383
                     /gene="Entpd2"
                     /gene_synonym="Cd39l1; NTPDase2"
                     /inference="alignment:Splign:2.1.0"
     exon            1384..1937
                     /gene="Entpd2"
                     /gene_synonym="Cd39l1; NTPDase2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1912..1917
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Entpd2"
                     /gene_synonym="Cd39l1; NTPDase2"
                     /note="hexamer: AATAAA"
     polyA_site      1935
                     /gene="Entpd2"
                     /gene_synonym="Cd39l1; NTPDase2"
                     /note="major polyA site"
ORIGIN      
        1 gttacagccc cgccccggag cctaactctg gggccccggc caccgggcct cccgctgcct
       61 gctgtccggg gtccctgctg tgttctcccg cgtgctccca tggctggaaa gttggtgtca
      121 ctggtgccac ccctgctgct ggctgccgtg ggcctcgccg gcctcctgct actgtgcgtc
      181 cctacccaag acgtccggga gccgcccgcc ctcaagtatg gcatcgttct ggatgctggc
      241 tcttcacaca catccatgtt tgtctacaag tggccagcgg acaaggaaaa tgacacaggt
      301 atcgtgggcc agcacagctc ttgcgatgtt cgaggtggtg gcatctccag ctacgcaaat
      361 gacccttcta gggcaggcca gagtctggtt gaatgtcttg aacaggcact tcgggatgtg
      421 cccaaagaca gatatgccag cactccactc tacctgggag ctacagcagg catgcgccta
      481 ctcaacctga ccagcccaga ggccacagcc aaggtgctgg aggcagtgac acagacgctc
      541 acacggtacc cctttgactt ccgtggtgcc cgcatcctct cgggacagga tgaaggggtg
      601 tttggctggg tgactgccaa ctacctgctg gagaacttca tcaagtatgg ctgggtaggc
      661 cggtggatac ggccaaggaa gggaactctg ggggccatgg accttggggg tgcctcaaca
      721 cagatcacct ttgagacaac cagtccatct gaagatccag ataatgaggt ccatttgcgg
      781 ctctatggcc agcattaccg tgtctacacc catagcttcc tctgctatgg ccgggaccag
      841 gttctccaga ggcttctggc cagtgccctc cagatccatc gcttccaccc ctgctggcca
      901 aagggctact ccacccaagt gctgctccgg gaagtctacc agtctccatg cactatgggt
      961 cagcgtcccc agaccttcaa cagcagtgcc actgtcagcc tgtcagggac cagcaacgct
     1021 gccctctgtc gtgacctcgt ctctgggctc ttcaatatct cctcctgtcc cttttcccaa
     1081 tgctccttca atggggtttt ccagcctccc gtggctggga acttcatagc cttttctgct
     1141 ttctactata ctgtagactt cctgaagaca gtgatggggc tgcctgtggg aaccctgaag
     1201 cagctggagg atgccacaga gaccacctgc aaccagacct gggctgagct tcaggcccga
     1261 gtacccggac agcagacccg cctgcctgac tactgcgctg tagccatgtt catacatcag
     1321 ctattgagcc gcggttatcg cttcgacgag cgctctttcc gtggagtggt cttcgaaaag
     1381 aaggcggcag acacggctgt cggctgggcg ctgggctaca tgctgaattt gaccaacctg
     1441 attcccgctg acctcccggg actacgtaag ggcacccact tcagctcctg ggttgctctc
     1501 ctgctgctct tcacagtcct gatcttggcg gctttggtcc tgctcttgcg ccaggtgcgc
     1561 tctgccaagt ccccaggcgc cctctagggg tgcgctggga gcttctccca actcccggct
     1621 atctctcttc ccgagggcat ctctgaccct gaagcagcct ggacggtcct tatctacact
     1681 cacagaaagt ctacatgggc agccctgagt gttctcaatt aatcctccgc tctcttcctg
     1741 ggatgtcagg tctcttagcc tgcgactcag ggtgaggtcc attccgagtg gagcctctgt
     1801 tctgattgat cttcagggcc ctgggtactt tctgtctggg cctttagaaa ggcaagcacc
     1861 agagactaca ggctaggagt cagctccatg cctacttgta aaaaaatttg taataaaaga
     1921 ttttttccta gagcagt
//
