LOCUS       NM_023119               1831 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus enolase 1, alpha non-neuron (Eno1), transcript variant
            3, mRNA.
ACCESSION   NM_023119 XM_001006583
VERSION     NM_023119.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1831)
  AUTHORS   Chen,L.J., Li,J.Y., Nguyen,P., He,M., Chen,Z.B., Subramaniam,S.,
            Shyy,J.Y. and Chien,S.
  TITLE     Single-cell RNA sequencing unveils unique transcriptomic signatures
            of endothelial cells and role of ENO1 in response to disturbed flow
  JOURNAL   Proc Natl Acad Sci U S A 121 (5), e2318904121 (2024)
   PUBMED   38261622
  REMARK    GeneRIF: Single-cell RNA sequencing unveils unique transcriptomic
            signatures of endothelial cells and role of ENO1 in response to
            disturbed flow.
REFERENCE   2  (bases 1 to 1831)
  AUTHORS   Chung,I.C., Huang,W.C., Huang,Y.T., Chen,M.L., Tsai,A.W., Wu,P.Y.
            and Yuan,T.T.
  TITLE     Unrevealed roles of extracellular enolase-1 (ENO1) in promoting
            glycolysis and pro-cancer activities in multiple myeloma via
            hypoxia-inducible factor 1alpha
  JOURNAL   Oncol Rep 50 (5) (2023)
   PUBMED   37800625
  REMARK    GeneRIF: Unrevealed roles of extracellular enolase-1 (ENO1) in
            promoting glycolysis and pro-cancer activities in multiple myeloma
            via hypoxia-inducible factor 1alpha.
REFERENCE   3  (bases 1 to 1831)
  AUTHORS   Kawakami,H., Chen,K.Q., Zhang,R., Pappas,M.P., Bailey,A.,
            Reisz,J.A., Corcoran,D., Nishinakamura,R., D'Alessandro,A. and
            Kawakami,Y.
  TITLE     Sall4 restricts glycolytic metabolism in limb buds through
            transcriptional regulation of glycolytic enzyme genes
  JOURNAL   Dev Biol 501, 28-38 (2023)
   PUBMED   37301463
REFERENCE   4  (bases 1 to 1831)
  AUTHORS   Huang,C.K., Lv,L., Chen,H., Sun,Y. and Ping,Y.
  TITLE     ENO1 promotes immunosuppression and tumor growth in pancreatic
            cancer
  JOURNAL   Clin Transl Oncol 25 (7), 2250-2264 (2023)
   PUBMED   36820953
  REMARK    GeneRIF: ENO1 promotes immunosuppression and tumor growth in
            pancreatic cancer.
REFERENCE   5  (bases 1 to 1831)
  AUTHORS   Chong,D., Gu,Y., Zhang,T., Xu,Y., Bu,D., Chen,Z., Xu,N., Li,L.,
            Zhu,X., Wang,H., Li,Y., Zheng,F., Wang,D., Li,P., Xu,L., Hu,Z. and
            Li,C.
  TITLE     Neonatal ketone body elevation regulates postnatal heart
            development by promoting cardiomyocyte mitochondrial maturation and
            metabolic reprogramming
  JOURNAL   Cell Discov 8 (1), 106 (2022)
   PUBMED   36220812
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1831)
  AUTHORS   Lucas,M., Goblet,C., Keller,A., Lamande,N., Gros,F., Whalen,R.G.
            and Lazar,M.
  TITLE     Modulation of embryonic and muscle-specific enolase gene products
            in the developing mouse hindlimb
  JOURNAL   Differentiation 51 (1), 1-7 (1992)
   PUBMED   1280607
REFERENCE   7  (bases 1 to 1831)
  AUTHORS   Keller,A., Ott,M.O., Lamande,N., Lucas,M., Gros,F., Buckingham,M.
            and Lazar,M.
  TITLE     Activation of the gene encoding the glycolytic enzyme beta-enolase
            during early myogenesis precedes an increased expression during
            fetal muscle development
  JOURNAL   Mech Dev 38 (1), 41-54 (1992)
   PUBMED   1525038
REFERENCE   8  (bases 1 to 1831)
  AUTHORS   Lalley,P.A., Minna,J.D. and Francke,U.
  TITLE     Conservation of autosomal gene synteny groups in mouse and man
  JOURNAL   Nature 274 (5667), 160-163 (1978)
   PUBMED   662012
REFERENCE   9  (bases 1 to 1831)
  AUTHORS   Lalley,P.A., Francke,U. and Minna,J.D.
  TITLE     Homologous genes for enolase, phosphogluconate dehydrogenase,
            phosphoglucomutase, and adenylate kinase are syntenic on mouse
            chromosome 4 and human chromosome 1p
  JOURNAL   Proc Natl Acad Sci U S A 75 (5), 2382-2386 (1978)
   PUBMED   209463
REFERENCE   10 (bases 1 to 1831)
  AUTHORS   D'Ancona,G.G. and Croce,C.M.
  TITLE     Assignment of the gene for enolase to mouse chromosome 4 using
            somatic cell hybrids
  JOURNAL   Cytogenet Cell Genet 19 (1), 1-6 (1977)
   PUBMED   891258
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BU526382.1 and BC083334.1.
            
            [WARNING] On Apr 15, 2024 this sequence was replaced by
            NM_023119.3.
            
            On Oct 30, 2007 this sequence version replaced NM_023119.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083334.1, BC024644.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-68                BU526382.1         4-71
            69-1831             BC083334.1         1-1763
FEATURES             Location/Qualifiers
     source          1..1831
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 81.24 cM"
     gene            1..1831
                     /gene="Eno1"
                     /gene_synonym="Eno-1; MBP-1; NNE"
                     /note="enolase 1, alpha non-neuron"
                     /db_xref="GeneID:13806"
                     /db_xref="MGI:MGI:95393"
     exon            1..144
                     /gene="Eno1"
                     /gene_synonym="Eno-1; MBP-1; NNE"
                     /inference="alignment:Splign:2.1.0"
     exon            145..238
                     /gene="Eno1"
                     /gene_synonym="Eno-1; MBP-1; NNE"
                     /inference="alignment:Splign:2.1.0"
     exon            239..334
                     /gene="Eno1"
                     /gene_synonym="Eno-1; MBP-1; NNE"
                     /inference="alignment:Splign:2.1.0"
     exon            335..393
                     /gene="Eno1"
                     /gene_synonym="Eno-1; MBP-1; NNE"
                     /inference="alignment:Splign:2.1.0"
     exon            394..463
                     /gene="Eno1"
                     /gene_synonym="Eno-1; MBP-1; NNE"
                     /inference="alignment:Splign:2.1.0"
     exon            464..597
                     /gene="Eno1"
                     /gene_synonym="Eno-1; MBP-1; NNE"
                     /inference="alignment:Splign:2.1.0"
     exon            598..820
                     /gene="Eno1"
                     /gene_synonym="Eno-1; MBP-1; NNE"
                     /inference="alignment:Splign:2.1.0"
     exon            821..1018
                     /gene="Eno1"
                     /gene_synonym="Eno-1; MBP-1; NNE"
                     /inference="alignment:Splign:2.1.0"
     exon            1019..1220
                     /gene="Eno1"
                     /gene_synonym="Eno-1; MBP-1; NNE"
                     /inference="alignment:Splign:2.1.0"
     exon            1221..1329
                     /gene="Eno1"
                     /gene_synonym="Eno-1; MBP-1; NNE"
                     /inference="alignment:Splign:2.1.0"
     exon            1330..1388
                     /gene="Eno1"
                     /gene_synonym="Eno-1; MBP-1; NNE"
                     /inference="alignment:Splign:2.1.0"
     exon            1389..1776
                     /gene="Eno1"
                     /gene_synonym="Eno-1; MBP-1; NNE"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggcttaac gagcaggaaa ggaagacaga gtgggaggcg cttagtgctg ctccggtaca
       61 gggtcgcgct cgcgtctgtc cttaaggctc tcctcggtgt ccacggcacc ctctttcctt
      121 gctttgcagc gatcctactg ccagaaattc gccatgtcta ttctcaggat ccacgccaga
      181 gagatctttg actcccgtgg gaatcccact gttgaggtcg atctgtacac cgcaaaaggt
      241 ctcttccgag ctgcggtgcc cagcggtgcg tccactggca tctacgaggc cctagaactc
      301 cgagacaatg ataagacccg cttcatgggg aagggtgtct cacaggctgt tgagcacatc
      361 aataaaacta ttgcgcctgc tctggttagc aagaaagtga atgttgtgga gcaagagaag
      421 attgacaagc tgatgatcga gatggacggc acagagaata aatctaaatt tggtgcaaat
      481 gccatcctgg gagtgtccct ggctgtctgc aaagctggtg ccgtggaaaa gggggtgccc
      541 ctttaccgcc acattgctga cttggccggc aaccctgaag tcatcctgcc tgtcccggct
      601 ttcaatgtga tcaacggtgg ttctcatgct ggcaacaagc tggccatgca agagttcatg
      661 atcctgcctg tgggggcatc cagcttccgg gaagccatgc gcattggagc agaggtttac
      721 cacaacctga agaacgtgat caaggagaag tacgggaagg acgccaccaa tgtgggtgat
      781 gagggtggat tcgcacctaa catcctggag aacaaagaag cactggagct gctcaagact
      841 gcaatcgcaa aggccggcta cactgaccag gttgtcattg gcatggatgt ggctgcctcc
      901 gagttctaca ggtctggcaa gtatgacctg gacttcaagt ctccggatga ccccagcagg
      961 tacatcactc ccgaccagct ggctgatctg tacaagtcct tcgtccagaa ctacccagtg
     1021 gtgtccatcg aagatccctt tgaccaggac gactggggcg cctggcagaa gttcacggct
     1081 agtgcgggca tccaggtggt gggcgatgac ctcacagtga ccaaccctaa gcggattgcc
     1141 aaggctgcga gcgagaagtc ctgcaactgc ctcttgctca aagtgaacca gatcggctct
     1201 gtgaccgaat ccctgcaggc gtgtaagctg gcccaatcca atggctgggg cgtcatggtg
     1261 tcccaccgat ctggggaaac tgaggacact ttcatcgcag acctggtggt ggggctctgc
     1321 actgggcaga tcaagactgg tgccccttgc cgatccgagc gcctggccaa gtacaatcag
     1381 atcctcagaa ttgaggaaga gctgggcagc aaagccaagt ttgctggcag gtccttcagg
     1441 aaccccctgg ccaaataaag catggaccgg agatccctgg agccaccagc tgctaggtcc
     1501 tctatccctg atgtcatccc agcagctcaa ggccagccca gtgcgtgccc ctcccatgtc
     1561 actgcttcct taggcatcca cacctgacca ccagaatccc tgctggagac ccagttttgc
     1621 aatcatgtga ttggtctgaa tcattgtttc tgtcacctga cttcccagct agtgtctgga
     1681 gccctcggaa ctccagtgta atctctaggg tgcccaccat caagatcccc ctccccccag
     1741 tggtttacat gcaaaaataa aagccgcaga agtccaaaaa aaaaaaaaaa aaaaaaaaaa
     1801 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//
